TR200002686T2 - Iridaceae ve Cimicifuga racemosadan elde edilen ekstrelerin ve tectorigeninin hiçbir uterotropik etkiye sahip olmayan bir estrojen-tipi, organ-seçiçi ilaç olarak kullanımı - Google Patents

Iridaceae ve Cimicifuga racemosadan elde edilen ekstrelerin ve tectorigeninin hiçbir uterotropik etkiye sahip olmayan bir estrojen-tipi, organ-seçiçi ilaç olarak kullanımı

Info

Publication number
TR200002686T2
TR200002686T2 TR2000/02686T TR200002686T TR200002686T2 TR 200002686 T2 TR200002686 T2 TR 200002686T2 TR 2000/02686 T TR2000/02686 T TR 2000/02686T TR 200002686 T TR200002686 T TR 200002686T TR 200002686 T2 TR200002686 T2 TR 200002686T2
Authority
TR
Turkey
Prior art keywords
tectorigen
iridaceae
estrogen
extracts
organ
Prior art date
Application number
TR2000/02686T
Other languages
English (en)
Inventor
Wuttke Wolfgang
Jarry Hubertus
Christoffel Volker
Spengler Barbara
Popp Michael
Original Assignee
Bionorica Arzneimittel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7861630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200002686(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bionorica Arzneimittel Gmbh filed Critical Bionorica Arzneimittel Gmbh
Publication of TR200002686T2 publication Critical patent/TR200002686T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Botany (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Mevcut bulus, Iridaceae ve Cimicifuga racemosadan elde edilen ekstrelerin ve tectorigeninin, kalp damar hastaliklarinin, özellikle ateroskleroz, osteoporoz ve degisim bozukluklarinin, örnegin ates basmalarinin önlenmesi veya hafifletilmesi gibi seçici tedavisi ve/veya önlenmesi için bir estrojen-tipi organ-seçiçi ilaç olarak kullanimi ile ilgilidir. Pratik olarak uterotrofik etkiler gözlenmemektedir.
TR2000/02686T 1998-03-19 1999-03-19 Iridaceae ve Cimicifuga racemosadan elde edilen ekstrelerin ve tectorigeninin hiçbir uterotropik etkiye sahip olmayan bir estrojen-tipi, organ-seçiçi ilaç olarak kullanımı TR200002686T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19812204A DE19812204A1 (de) 1998-03-19 1998-03-19 Verwendung von Extrakten aus Cimicifuga racemosa und Belamcanda sinensis als estrogenartiges organselektives Arzneimittel ohne uterotrope Wirkung

Publications (1)

Publication Number Publication Date
TR200002686T2 true TR200002686T2 (tr) 2000-12-21

Family

ID=7861630

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02686T TR200002686T2 (tr) 1998-03-19 1999-03-19 Iridaceae ve Cimicifuga racemosadan elde edilen ekstrelerin ve tectorigeninin hiçbir uterotropik etkiye sahip olmayan bir estrojen-tipi, organ-seçiçi ilaç olarak kullanımı

Country Status (21)

Country Link
EP (1) EP1064009B2 (tr)
JP (2) JP2002506827A (tr)
KR (1) KR100623333B1 (tr)
CN (2) CN100444867C (tr)
AT (1) ATE225182T1 (tr)
AU (1) AU755900C (tr)
BR (1) BR9908256A (tr)
CA (1) CA2321444C (tr)
CZ (1) CZ292684B6 (tr)
DE (2) DE19812204A1 (tr)
DK (1) DK1064009T4 (tr)
ES (1) ES2184427T5 (tr)
HK (1) HK1035660A1 (tr)
HU (1) HU227694B1 (tr)
MX (1) MXPA00007986A (tr)
PL (1) PL194096B1 (tr)
PT (1) PT1064009E (tr)
RU (2) RU2228188C2 (tr)
SE (1) SE1064009T4 (tr)
TR (1) TR200002686T2 (tr)
WO (1) WO1999047149A1 (tr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000302667A (ja) * 1999-04-23 2000-10-31 Kobe Tennenbutsu Kagaku Kk 豊胸促進剤
JP5106739B2 (ja) * 2000-06-29 2012-12-26 クイック−メッド テクノロジーズ、インク. 化粧品組成物および方法
IL145876A0 (en) 2000-10-17 2002-07-25 Pfizer Prod Inc Methods and kits for improving vascular health
DE10054641A1 (de) * 2000-11-03 2002-05-16 Schaper & Bruemmer Gmbh Verwendung einer Zubereitung von Cimicifuga racemosa
DE10123503A1 (de) * 2001-05-15 2002-11-21 Bionorica Ag Verwendung von Extrakten und Zubereitungen aus Irisgewächsen und Tectorigenin als organselektives Arzneimittel zur Behandlung von sexualhormon-abhängigen Erkrankungen des Urogenitaltraktes
DE10127897B4 (de) * 2001-06-08 2006-04-20 Bionorica Ag Manteltablette mit Pflanzentrockenextrakten
DE10146159A1 (de) * 2001-09-19 2003-04-10 Bionorica Ag Verwendung von Extrakten aus Cimicifuga-Arten als organselektives Arzneimittel zur Behandlung von sexualhormonabhängigen Erkrankungen des Urogenitaltraktes
EP1325681A1 (en) * 2001-12-11 2003-07-09 Société des Produits Nestlé S.A. Composition for promotion of bone growth and maintenance of bone health
DE10206390A1 (de) * 2002-02-15 2003-08-28 Bionorica Ag Verwendung von selektiv den Estrogenrezeptor beta modulierenden phytoestrogenhaltigen Extrakten
JP4605984B2 (ja) * 2002-12-20 2011-01-05 アサヒビール株式会社 ストレス緩和剤
US7902253B2 (en) * 2003-05-15 2011-03-08 Chengdu Dikang Pharmaceutical Institute Isoflavone derivatives of tectorigenin, the preparation thereof and the antiviral medicine containing the same as an effective constituent
EP1591143A1 (en) * 2004-04-26 2005-11-02 Schaper & Brümmer Gmbh & Co. Kg Composition comprising a combination of Calcium, Cimicifugae racemosae rhizoma and vitamin D and its use as a pharmaceutical in conditions or disorders associated with or resulting from calcium deficiency or as a nutritional supplement
EP1588739A1 (en) * 2004-04-23 2005-10-26 Schaper & Brümmer Gmbh & Co. Kg Composition comprising a combination of calcium, Cimicifugae racemosae rhizoma and vitamin D and its use as a pharmaceutical in conditions or disorders associated with or resulting from calcium deficiency or as a nutritional supplement
US7887851B2 (en) 2004-06-07 2011-02-15 Kao Corporation Aromatase activator
CN100381435C (zh) * 2005-03-24 2008-04-16 深圳海王药业有限公司 射干总黄酮提取物及其制备方法和其在药物制备中的应用
EP1745796A1 (de) 2005-07-19 2007-01-24 Bionorica Research GmbH Kombinationspräparat insbesondere zur Therapie des Prostatakarzinoms
CN101057854B (zh) * 2006-05-31 2010-05-12 南京大学 升麻环菠萝蜜烷型三萜类化合物在抗骨质疏松及更年期综合症的用途
DE102007044916A1 (de) 2007-09-19 2009-04-23 Bionorica Ag Kosmetische oder dermatologische Zusammensetzung zur topischen Verwendung
KR100928013B1 (ko) * 2008-01-25 2009-11-24 이화여자대학교 산학협력단 범부채 추출물을 이용한 돌피의 생장 촉진방법 및 이방법을 적용한 중금속 오염 토양의 정화방법
CN101797265A (zh) * 2010-04-09 2010-08-11 中国人民解放军第二军医大学 射干总异黄酮或异黄酮类化合物在制备防治妇女病的药物或食品中的应用
EP2545932A1 (de) 2011-07-12 2013-01-16 Bionorica Se Ausgewählte Cimicifuga-Fraktionen zur Behandlung von Osteoporose
WO2013007807A1 (de) 2011-07-12 2013-01-17 Bionorica Se Ausgewählte cimicifuga-fraktionen zur behandlung von osteoporose
EP2620155A1 (de) 2012-01-30 2013-07-31 Bionorica SE Arzneimittel enthaltend Cimicifuga zur Anwendung bei der Behandlung von Sarkopenie und Herzmuskelschwäche
CN102525907B (zh) * 2012-02-22 2013-06-05 四川省中医药科学院 鸢尾苷元磺酸钠注射液
CN102631363A (zh) * 2012-04-11 2012-08-15 李超生 鸢尾苷在制备防治骨质疏松症的药物中的应用
CN104394874A (zh) * 2012-06-22 2015-03-04 国鼎生物科技股份有限公司 用于治疗动脉硬化性血管病的方法和组合物
AU2013285492B2 (en) 2012-07-03 2015-11-12 Max Zeller Soehne Ag Novel pharmacological use of Cimicifuga extract
JP2014091706A (ja) * 2012-11-02 2014-05-19 Kao Corp Glp−1分泌促進剤
KR101965849B1 (ko) * 2017-03-07 2019-04-04 주식회사 엘지생활건강 텍토리게닌 7-0-자일로실글루코시드를 포함하는 여성 갱년기 증상 완화용 조성물
KR101964841B1 (ko) * 2017-03-07 2019-08-07 주식회사 엘지생활건강 여성 갱년기 증상 개선용 조성물
TWI761372B (zh) * 2017-09-22 2022-04-21 日商東洋新藥股份有限公司 組合物
EP3906040A1 (en) 2018-12-31 2021-11-10 Max Zeller Söhne AG Combination of cimicifuga and petasites extracts for anticancer therapy and prophylaxis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6330417A (ja) * 1986-07-23 1988-02-09 Tsumura Juntendo Inc 抗アレルギ−剤
DE69601765T2 (de) * 1995-09-07 1999-07-08 Oreal Extrakt von Iridaceen und Zusammensetzungen, die ihn enthalten
CA2235481A1 (en) * 1995-10-23 1997-05-01 Sean M. Kerwin Compositions and methods for treating bone deficit conditions
JPH09301884A (ja) * 1996-05-15 1997-11-25 Ichimaru Pharcos Co Ltd ヒオウギ抽出物及びα−ヒドロキシ酸を含有するテストステロン5α−リダクターゼ阻害剤とその応用
JPH107580A (ja) * 1996-06-15 1998-01-13 Michio Yoshida コラゲナ−ゼ阻害剤
JP3665848B2 (ja) * 1996-09-18 2005-06-29 木村 幸代 ヒメヒオウギズイセン球根抽出液の発酵飲料及びその製造方法
DE19652183C1 (de) * 1996-12-14 1998-02-12 Schaper & Bruemmer Gmbh Verwendung eines Extraktes aus Cimicifuga racemosa

Also Published As

Publication number Publication date
CN100581541C (zh) 2010-01-20
ES2184427T5 (es) 2008-12-16
AU755900C (en) 2005-04-21
WO1999047149A1 (de) 1999-09-23
CZ20002810A3 (cs) 2000-12-13
DE19812204A1 (de) 1999-11-04
HU227694B1 (en) 2011-12-28
CZ292684B6 (cs) 2003-11-12
AU755900B2 (en) 2003-01-02
CA2321444A1 (en) 1999-09-23
KR20010040829A (ko) 2001-05-15
EP1064009A1 (de) 2001-01-03
EP1064009B1 (de) 2002-10-02
EP1064009B2 (de) 2008-07-30
SE1064009T4 (sv) 2008-09-23
ATE225182T1 (de) 2002-10-15
PL342486A1 (en) 2001-06-04
RU2003137324A (ru) 2005-06-10
EP1064009B9 (de) 2003-02-05
CA2321444C (en) 2012-10-02
SE1064009T5 (sv) 2003-04-15
DK1064009T4 (da) 2008-08-25
ES2184427T3 (es) 2003-04-01
CN1293575A (zh) 2001-05-02
DK1064009T3 (da) 2002-11-04
HUP0200921A2 (hu) 2002-12-28
RU2263505C2 (ru) 2005-11-10
RU2228188C2 (ru) 2004-05-10
AU3146699A (en) 1999-10-11
CN1509712A (zh) 2004-07-07
HK1035660A1 (en) 2001-12-07
HUP0200921A3 (en) 2004-05-28
CN100444867C (zh) 2008-12-24
PT1064009E (pt) 2003-02-28
BR9908256A (pt) 2000-12-12
SE1064009T3 (sv) 2003-01-21
MXPA00007986A (es) 2002-08-06
KR100623333B1 (ko) 2006-12-05
JP2002506827A (ja) 2002-03-05
DE59902932D1 (de) 2002-11-07
PL194096B1 (pl) 2007-04-30
JP2010132699A (ja) 2010-06-17

Similar Documents

Publication Publication Date Title
TR200002686T2 (tr) Iridaceae ve Cimicifuga racemosadan elde edilen ekstrelerin ve tectorigeninin hiçbir uterotropik etkiye sahip olmayan bir estrojen-tipi, organ-seçiçi ilaç olarak kullanımı
NO950879L (no) 3-fenylpyrrolidin-derivater
FI962246A0 (fi) Apoptoosia inhiboivat koostumukset, koostumusten puhdistusmenetelmät ja niiden käyttö
NO20063553L (no) Kjemobeskyttende midler fra korsblomstfro og spirer
DK1079824T3 (da) Triterpen-sammensætninger og fremgangsmåder til anvendelse deraf
DK0835120T3 (da) Farmaceutiske sammensætninger indeholdende aktive ingredienser på basis af urter, fremgangsmåde til fremstilling af sammens
WO2002047706A3 (en) Selective cox-2 inhibition from plant extracts
WO2005112965A3 (en) Botanical anti-inflammatory compositions and methods
ATE305230T1 (de) Verbessertes hartdragierverfahren
NO20006430D0 (no) Neurobeskyttende sammensetning for forhindring og/eller behandling av nerve- og atferdsforandringer på grunn av angsttilstander eller depresjoner
MX2010003726A (es) Composiciones herbarias y metodos de tratamiento de trastornos hepaticos.
NO975858D0 (no) Anvendelse av et ekstrakt av Cimicifuga racemosa
BR9910941A (pt) Extratos de hypericum perforatum e formulações contendo os mesmos
DE69310739T2 (de) Biozide zusammensetzung die senfsamenextrakt enthält
IL144199A0 (en) Novel bretylium compositions and kits, and their use in preventing and treating cardiovascular conditions
ES2034888A1 (es) Procedimiento de obtencion de la fraccion acida total de los extractos lipidicos de los frutos del sabal serrulata.
ATE359083T1 (de) Zwiebelextrakte
WO2003072053A3 (en) Compounds for treatment of copper overload
DK1107776T3 (da) Tørekstrakt af hennaplante, fremgangsmåde til fremstilling heraf og anvendelse heraf
ATE328480T1 (de) Fungizide wirkstoffkombinationen
ATE317384T1 (de) Lta4 hydrolase-hemmer
WO2020084347A3 (en) Combination of a kinase inhibitor and an immunotherapeutic agent, compositions and methods comprising the same
MD1496G2 (ro) Procedeu de uscare a seminţelor de bostan
FR2802773B1 (fr) Utilisation de dechets ou d'extraits de bois en tant qu'insecticide
TH1801001476A (th) วิธีการของการเตรียมสารสกัดจากต้นแอมโบรเซีย