KR100483779B1 - 지혈성디펩티드를포함하는약학조성물 - Google Patents
지혈성디펩티드를포함하는약학조성물 Download PDFInfo
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- KR100483779B1 KR100483779B1 KR1019980702431A KR19980702431A KR100483779B1 KR 100483779 B1 KR100483779 B1 KR 100483779B1 KR 1019980702431 A KR1019980702431 A KR 1019980702431A KR 19980702431 A KR19980702431 A KR 19980702431A KR 100483779 B1 KR100483779 B1 KR 100483779B1
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- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53870195A | 1995-10-03 | 1995-10-03 | |
| US8/538701 | 1995-10-03 | ||
| US08/538701 | 1995-10-03 | ||
| US08/614,764 | 1996-03-13 | ||
| US8/614,764 | 1996-03-13 | ||
| US8/614764 | 1996-03-13 | ||
| US08/614,764 US5902790A (en) | 1995-10-03 | 1996-03-13 | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| PCT/US1996/015856 WO1997012625A1 (en) | 1995-10-03 | 1996-10-02 | Pharmaceutical angiostatic dipeptide compositions and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR19990063958A KR19990063958A (ko) | 1999-07-26 |
| KR100483779B1 true KR100483779B1 (ko) | 2007-03-02 |
Family
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Family Applications (1)
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| KR1019980702431A KR100483779B1 (ko) | 1995-10-03 | 1996-10-02 | 지혈성디펩티드를포함하는약학조성물 |
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| EP (1) | EP0869808B1 (de) |
| JP (2) | JP3679129B2 (de) |
| KR (1) | KR100483779B1 (de) |
| CN (1) | CN1128636C (de) |
| AT (1) | ATE332702T1 (de) |
| AU (1) | AU714846B2 (de) |
| BR (1) | BR9610838A (de) |
| CA (1) | CA2233457C (de) |
| CZ (1) | CZ298345B6 (de) |
| DE (1) | DE69636343T2 (de) |
| DK (1) | DK0869808T3 (de) |
| EA (1) | EA001146B1 (de) |
| ES (1) | ES2268710T3 (de) |
| HU (1) | HUP9902105A3 (de) |
| IL (1) | IL123889A0 (de) |
| MX (1) | MX9802564A (de) |
| NO (1) | NO326298B1 (de) |
| NZ (1) | NZ319907A (de) |
| PL (1) | PL186123B1 (de) |
| SK (1) | SK283677B6 (de) |
| TR (1) | TR199800653T1 (de) |
| WO (1) | WO1997012625A1 (de) |
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| US5902790A (en) * | 1995-10-03 | 1999-05-11 | Cytran, Inc. | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| US6060452A (en) * | 1996-03-13 | 2000-05-09 | Cytran, Inc. | Analogs of L-Glu-L-Trp having pharmacological activity |
| AU3467099A (en) * | 1998-04-03 | 1999-10-25 | Cytran Ltd. | Methods for production of therapeutic cytokines |
| ES2381775T3 (es) | 2000-08-04 | 2012-05-31 | Dmi Biosciences, Inc. | Procedimiento del uso de dicetopiperazinas y composición que las contiene |
| CA2627862C (en) * | 2001-01-02 | 2009-12-22 | Imtm Gmbh | Use of inhibitors of dipeptidyl peptidase iv (dp iv) in combination with inhibitors of alanyl-aminopeptidase (apn) |
| DE10100052A1 (de) * | 2001-01-02 | 2002-07-11 | Inst Medizintechnologie Magdeb | Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose |
| US20030087830A1 (en) * | 2001-06-12 | 2003-05-08 | Eric Dupont | Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof |
| AU2004241101B2 (en) | 2003-05-15 | 2010-05-13 | Ampio Pharmaceuticals, Inc. | Treatment of T-cell mediated diseases |
| WO2005016326A2 (en) * | 2003-07-11 | 2005-02-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| BRPI0414497A (pt) | 2003-09-17 | 2006-11-14 | Us Gov Health & Human Serv | análogos de talidomida |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| EP1848541A4 (de) * | 2005-02-07 | 2013-01-16 | Pharmalight Inc | Verfahren und vorrichtung zur ophthalmischen verabreichung von pharmazeutischen wirksstoffen |
| CA2569204A1 (en) * | 2006-11-28 | 2008-05-28 | Apotex Technologies Inc. | Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan |
| CA2571645A1 (en) * | 2006-12-19 | 2008-06-19 | Apotex Technologies Inc. | Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture |
| CN101657210A (zh) * | 2007-02-13 | 2010-02-24 | 希克龙制药公司 | 粘膜疾病引起的组织退化、损伤或损害的治疗或预防方法 |
| CA2579119C (en) | 2007-02-16 | 2013-03-05 | Apotex Technologies Inc. | Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan |
| EA201070295A1 (ru) * | 2007-08-23 | 2010-10-29 | Сиклоун Фармасьютикалз, Инк. | Лечение рака легких |
| US8217047B2 (en) | 2008-05-27 | 2012-07-10 | Dmi Acquisition Corp. | Therapeutic methods and compounds |
| DE102008032828A1 (de) * | 2008-07-02 | 2010-01-07 | Technische Universität Dresden | Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel |
| WO2012033792A2 (en) | 2010-09-07 | 2012-03-15 | Dmi Acquisition Corp. | Treatment of diseases |
| WO2013055734A1 (en) | 2011-10-10 | 2013-04-18 | Ampio Pharmaceuticals, Inc. | Treatment of degenerative joint disease |
| JP2014530063A (ja) | 2011-10-10 | 2014-11-17 | アンピオ ファーマシューティカルズ，インコーポレイテッド | 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法 |
| AU2012328605B9 (en) | 2011-10-28 | 2017-08-03 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
| CN102631464B (zh) * | 2012-05-18 | 2013-07-31 | 崔新明 | 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法 |
| SG11201506267XA (en) | 2013-03-15 | 2015-09-29 | Ampio Pharmaceuticals Inc | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| CA2958080A1 (en) | 2014-08-18 | 2016-02-25 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744239B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| EP3310375A4 (de) | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen |
| SG11202001595SA (en) * | 2017-08-31 | 2020-03-30 | Singapore Health Serv Pte Ltd | Angio-3 for treatment of retinal angiogenic diseases |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992017191A1 (en) * | 1991-04-01 | 1992-10-15 | Cytoven | Pharmaceutical dipeptide compositions and methods of use thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH611878A5 (de) * | 1974-07-04 | 1979-06-29 | Takeda Chemical Industries Ltd | |
| US4191753A (en) * | 1978-11-06 | 1980-03-04 | University Of Miami | Anti-hypertensive peptide analogs |
| EP0346501B1 (de) * | 1987-12-30 | 1992-07-29 | Vsesojuzny Kardiologichesky Nauchny Tsentr Akademii Meditsinskikh Nauk Sssr | Arzneimittelzubereitung zur behandlung des immunmangels |
| US5728680A (en) * | 1987-12-30 | 1998-03-17 | Cytoven J.V. | Methods for normalizing numbers of lymphocytes |
| GR1000608B (el) * | 1988-07-21 | 1992-08-31 | Erba Carlo Spa | Μεθοδος για την παρασκευη ανταγωνιστων bombesin. |
| SU1642398A1 (ru) * | 1988-12-21 | 1991-04-15 | Ростовский медицинский институт | Способ лечени синуитов у детей |
| US5770576A (en) * | 1989-08-30 | 1998-06-23 | Cytran, Inc. | Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity |
| US5902790A (en) * | 1995-10-03 | 1999-05-11 | Cytran, Inc. | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| RU1827255C (ru) * | 1990-10-22 | 1993-07-15 | Киевский государственный институт усовершенствования врачей | Способ лечени туберкулеза легких |
| JP3068656B2 (ja) * | 1991-03-07 | 2000-07-24 | アピ株式会社 | 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物 |
| RU2014063C1 (ru) * | 1991-04-23 | 1994-06-15 | Сочинский научно-исследовательский институт курортологии и физиотерапии | Способ лечения подострых воспалительных заболеваний гениталий |
| WO1993008815A1 (en) * | 1991-10-28 | 1993-05-13 | Cytoven | Pharmaceutical dipeptide compositions and methods of use thereof |
| AU7392294A (en) * | 1993-07-21 | 1995-02-20 | Vladimir Khatskelevich Khavinson | Pharmaceutical with immunomodulating activity |
| JPH09503205A (ja) * | 1993-09-24 | 1997-03-31 | ザ ユニバーシティ オブ サザーン カリフォルニア | 組織修復におけるアンギオテンシン▲ｉｉ▼類似体の使用 |
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1996
- 1996-03-13 US US08/614,764 patent/US5902790A/en not_active Expired - Lifetime
- 1996-10-02 AT AT96934021T patent/ATE332702T1/de not_active IP Right Cessation
- 1996-10-02 WO PCT/US1996/015856 patent/WO1997012625A1/en active IP Right Grant
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- 1996-10-02 CN CN96197430A patent/CN1128636C/zh not_active Expired - Lifetime
- 1996-10-02 DK DK96934021T patent/DK0869808T3/da active
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- 1996-10-02 EA EA199800357A patent/EA001146B1/ru not_active IP Right Cessation
- 1996-10-02 IL IL12388996A patent/IL123889A0/xx unknown
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- 1996-10-02 BR BR9610838-0A patent/BR9610838A/pt not_active Application Discontinuation
- 1996-10-02 TR TR1998/00653T patent/TR199800653T1/xx unknown
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- 1996-10-02 CA CA002233457A patent/CA2233457C/en not_active Expired - Lifetime
- 1996-10-02 EP EP96934021A patent/EP0869808B1/de not_active Expired - Lifetime
- 1996-10-02 ES ES96934021T patent/ES2268710T3/es not_active Expired - Lifetime
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1998
- 1998-03-30 NO NO19981436A patent/NO326298B1/no not_active IP Right Cessation
- 1998-04-01 MX MX9802564A patent/MX9802564A/es unknown
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1999
- 1999-03-01 US US09/260,190 patent/US6096713A/en not_active Expired - Lifetime
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2000
- 2000-02-17 US US09/506,430 patent/US6911431B1/en not_active Expired - Fee Related
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2005
- 2005-03-15 JP JP2005074079A patent/JP2005194287A/ja not_active Withdrawn
- 2005-05-16 US US11/129,367 patent/US20060094665A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992017191A1 (en) * | 1991-04-01 | 1992-10-15 | Cytoven | Pharmaceutical dipeptide compositions and methods of use thereof |
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