MX9802564A - Composiciones de dipeptidos angioestaticas farmaceuticas y metodos para usar las mismas. - Google Patents

Composiciones de dipeptidos angioestaticas farmaceuticas y metodos para usar las mismas.

Info

Publication number
MX9802564A
MX9802564A MX9802564A MX9802564A MX9802564A MX 9802564 A MX9802564 A MX 9802564A MX 9802564 A MX9802564 A MX 9802564A MX 9802564 A MX9802564 A MX 9802564A MX 9802564 A MX9802564 A MX 9802564A
Authority
MX
Mexico
Prior art keywords
methods
pharmaceutical
angiostatic
dipeptide
compositions
Prior art date
Application number
MX9802564A
Other languages
English (en)
Inventor
Lawrence R Green
John W Blasecki
Original Assignee
Cytran Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytran Ltd filed Critical Cytran Ltd
Publication of MX9802564A publication Critical patent/MX9802564A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Se describen método para inhibir la neovascularizacion en un sujeto administrando al sujeto una preparacion farmacéutica de R'-Glu-Trp-R".
MX9802564A 1995-10-03 1998-04-01 Composiciones de dipeptidos angioestaticas farmaceuticas y metodos para usar las mismas. MX9802564A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53870195A 1995-10-03 1995-10-03
US08/614,764 US5902790A (en) 1995-10-03 1996-03-13 Pharmaceutical angiostatic dipeptide compositions and method of use thereof

Publications (1)

Publication Number Publication Date
MX9802564A true MX9802564A (es) 1998-11-30

Family

ID=27065900

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9802564A MX9802564A (es) 1995-10-03 1998-04-01 Composiciones de dipeptidos angioestaticas farmaceuticas y metodos para usar las mismas.

Country Status (23)

Country Link
US (4) US5902790A (es)
EP (1) EP0869808B1 (es)
JP (2) JP3679129B2 (es)
KR (1) KR100483779B1 (es)
CN (1) CN1128636C (es)
AT (1) ATE332702T1 (es)
AU (1) AU714846B2 (es)
BR (1) BR9610838A (es)
CA (1) CA2233457C (es)
CZ (1) CZ298345B6 (es)
DE (1) DE69636343T2 (es)
DK (1) DK0869808T3 (es)
EA (1) EA001146B1 (es)
ES (1) ES2268710T3 (es)
HU (1) HUP9902105A3 (es)
IL (1) IL123889A0 (es)
MX (1) MX9802564A (es)
NO (1) NO326298B1 (es)
NZ (1) NZ319907A (es)
PL (1) PL186123B1 (es)
SK (1) SK283677B6 (es)
TR (1) TR199800653T1 (es)
WO (1) WO1997012625A1 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US6060452A (en) * 1996-03-13 2000-05-09 Cytran, Inc. Analogs of L-Glu-L-Trp having pharmacological activity
AU3467099A (en) * 1998-04-03 1999-10-25 Cytran Ltd. Methods for production of therapeutic cytokines
EP1311269B1 (en) 2000-08-04 2012-02-29 DMI Biosciences, Inc. Method of using diketopiperazines and composition containing them
DE10100052A1 (de) * 2001-01-02 2002-07-11 Inst Medizintechnologie Magdeb Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose
CN100579582C (zh) * 2001-01-02 2010-01-13 Imtm股份有限公司 联合应用酶抑制剂及其药学组合物在制备治疗和预防动脉硬化、预防和治疗根据杰尔－库姆斯分类法分类的ⅰ型过敏反应以及治疗和预防与毛囊和表皮角化过度和角质细胞的过度增殖相关的皮肤疾病的药物中的用途
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
ES2572975T3 (es) 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
WO2005016326A2 (en) * 2003-07-11 2005-02-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
US7973057B2 (en) 2003-09-17 2011-07-05 The United States Of America As Represented By The Department Of Health And Human Services Thalidomide analogs
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
CA2569204A1 (en) 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) * 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
KR20090119897A (ko) * 2007-02-13 2009-11-20 사이클론 파아머슈티컬 인코오퍼레이티드 점막의 질환으로 인한 조직 악화, 상처 또는 손상을 치료 또는 예방하는 방법
CA2579119C (en) * 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
EA201070295A1 (ru) * 2007-08-23 2010-10-29 Сиклоун Фармасьютикалз, Инк. Лечение рака легких
EP2300011A4 (en) 2008-05-27 2012-06-20 Dmi Life Sciences Inc METHODS AND THERAPEUTIC COMPOUNDS
DE102008032828A1 (de) * 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
US8507496B2 (en) 2010-09-07 2013-08-13 Dmi Acquisition Corp. Treatment of diseases
US9925300B2 (en) 2011-10-10 2018-03-27 Ampio Pharmaceuticals, Inc. Implantable medical devices with increased immune tolerance, and methods for making and implanting
EP3721884A1 (en) 2011-10-10 2020-10-14 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease with da-dkp (= aspartyl-alanyl diketopiperazine)
WO2013063413A1 (en) 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds
CN102631464B (zh) * 2012-05-18 2013-07-31 崔新明 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
JP6723222B2 (ja) 2014-08-18 2020-07-15 アンピオ ファーマシューティカルズ，インコーポレイテッド 関節病態の治療
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744239B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
WO2016209969A1 (en) 2015-06-22 2016-12-29 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
WO2019043649A2 (en) * 2017-08-31 2019-03-07 Singapore Health Services Pte Ltd ANGIO -3 FOR THE TREATMENT OF RETINAL ANGIOGENIC DISEASES

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997516A (en) * 1974-07-04 1976-12-14 Takeda Chemical Industries, Ltd. Method for protecting guanidino group and restoring the same
US4191753A (en) * 1978-11-06 1980-03-04 University Of Miami Anti-hypertensive peptide analogs
US5728680A (en) * 1987-12-30 1998-03-17 Cytoven J.V. Methods for normalizing numbers of lymphocytes
WO1989006134A1 (en) * 1987-12-30 1989-07-13 Vsesojuzny Kardiologichesky Nauchny Tsentr Akademi Pharmaceutical preparation for treating immunodeficiency conditions
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
SU1642398A1 (ru) * 1988-12-21 1991-04-15 Ростовский медицинский институт Способ лечени синуитов у детей
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
RU1827255C (ru) * 1990-10-22 1993-07-15 Киевский государственный институт усовершенствования врачей Способ лечени туберкулеза легких
JP3068656B2 (ja) * 1991-03-07 2000-07-24 アピ株式会社 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物
AU668088B2 (en) * 1991-04-01 1996-04-26 Cytran Ltd. Pharmaceutical dipeptide compositions and methods of use thereof
RU2014063C1 (ru) * 1991-04-23 1994-06-15 Сочинский научно-исследовательский институт курортологии и физиотерапии Способ лечения подострых воспалительных заболеваний гениталий
DE69230500D1 (de) * 1991-10-28 2000-02-03 Cytran Ltd Pharmazeutische Dipeptid Zusammensetzungen und Verwendungsmethoden.
WO1995003067A1 (en) * 1993-07-21 1995-02-02 Khavinson Vladimir Khatskelevi Pharmaceutical with immunomodulating activity
WO1995008565A1 (en) * 1993-09-24 1995-03-30 The University Of Southern California Use of angiotensin ii analogs in tissue repair

Also Published As

Publication number Publication date
EP0869808A1 (en) 1998-10-14
WO1997012625A1 (en) 1997-04-10
KR100483779B1 (ko) 2007-03-02
ATE332702T1 (de) 2006-08-15
US6096713A (en) 2000-08-01
KR19990063958A (ko) 1999-07-26
SK42398A3 (en) 1998-10-07
US5902790A (en) 1999-05-11
SK283677B6 (sk) 2003-11-04
CZ298345B6 (cs) 2007-09-05
CN1128636C (zh) 2003-11-26
AU7254096A (en) 1997-04-28
CA2233457C (en) 2004-08-03
US6911431B1 (en) 2005-06-28
NZ319907A (en) 2000-09-29
CN1198673A (zh) 1998-11-11
DK0869808T3 (da) 2006-11-13
NO981436D0 (no) 1998-03-30
JP3679129B2 (ja) 2005-08-03
BR9610838A (pt) 1999-12-21
JP2005194287A (ja) 2005-07-21
ES2268710T3 (es) 2007-03-16
EA001146B1 (ru) 2000-10-30
AU714846B2 (en) 2000-01-13
EA199800357A1 (ru) 1998-10-29
JPH11504943A (ja) 1999-05-11
CZ91398A3 (cs) 1998-11-11
PL186123B1 (pl) 2003-10-31
CA2233457A1 (en) 1997-04-10
DE69636343D1 (de) 2006-08-24
PL326149A1 (en) 1998-08-31
HUP9902105A3 (en) 2001-02-28
DE69636343T2 (de) 2007-07-19
TR199800653T1 (xx) 1998-06-22
HUP9902105A2 (hu) 1999-09-28
NO326298B1 (no) 2008-11-03
US20060094665A1 (en) 2006-05-04
IL123889A0 (en) 1998-10-30
NO981436L (no) 1998-05-19
EP0869808B1 (en) 2006-07-12

Similar Documents

Publication Publication Date Title
IL123889A0 (en) Pharmaceutical angiostatic dipeptide compositions and methods of use thereof
MY115662A (en) Novel compounds with analgesic effect
MX9700081A (es) Composiciones farmaceuticas de tacrina.
IL76932A (en) Synergistic pharmaceutical analgesic compositions containing dihydrocodeine and ibuprofen
HUP9900605A3 (en) Lipopolyamines as transfection agents, preparation and use thereof and pharmaceutical compositions containing them
MY119403A (en) Novel compounds with analgesic effect.
MY132705A (en) Novel compounds with analgesic effect
CA2264852A1 (en) Use of methylphenidate or a pharmaceutically acceptable salt thereof
IL103303A (en) Pharmaceutical compositions containing ibuprofen and codeine for relief of chronic pain
GEP20022783B (en) Method of Preventing and Delaying Onset of Alzheimer's Disease and Composition Therefor
IL129762A0 (en) Novel macromolecules methods for their preparation pharmaceutical compositions thereof and their use as anti-influenza agents
EP0783299A4 (en) COMPOUNDS AND COMPOSITIONS FOR THE ADMINISTRATION OF ACTIVE SUBSTANCES
IL118637A0 (en) Oral pharmaceutical compositions of S(+)-ibuprofen
RO116342B1 (ro) Compoziţie farmaceutică lichidă, orală
BG103657A (en) New modifications of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminebenzene and methods for their prepration
NZ318282A (en) Pharmaceutical formulation containing amoxycillin and clavulanate in a weight ratio of 12:1 and 20:1
EP0441192A3 (en) Retroisosteric dipeptides, their preparation and use as renin inhibitors in pharmaceutical compositions
ZA967880B (en) Compositions and methods for inhibition of the patho-physiologic actions in mammals in tumor necrosis facto-alpha
CA2202397A1 (en) Compositions comprising carbonate/bicarbonate buffered dichloroacetic acid and methods for treatment of metabolic and cardiovascular disorders
GB9424766D0 (en) Pharmaceutical composition
HUP9904027A3 (en) Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenerative diseases
NZ332655A (en) Pharmaceutical compositions containing diclofenac and alkali metal bicarbonates
EP0441191A3 (en) Retroisosteric dipeptides, their preparation and use as renin inhibitors in pharmaceutical compositions
AU3937693A (en) Methods and compositions for oral delivery of therapeutic agents
GR1002576B (el) Φαρμακευτικες συνθεσεις και μια μεθοδος παρασκευης τους.