HUP9902105A2 - Angiosztatikus dipeptideket tartalmazó gyógyászati készítmények és ezek alkalmazása - Google Patents

Angiosztatikus dipeptideket tartalmazó gyógyászati készítmények és ezek alkalmazása

Info

Publication number
HUP9902105A2
HUP9902105A2 HU9902105A HUP9902105A HUP9902105A2 HU P9902105 A2 HUP9902105 A2 HU P9902105A2 HU 9902105 A HU9902105 A HU 9902105A HU P9902105 A HUP9902105 A HU P9902105A HU P9902105 A2 HUP9902105 A2 HU P9902105A2
Authority
HU
Hungary
Prior art keywords
angiostatic
pharmaceutical
methods
dipeptide
compositions
Prior art date
Application number
HU9902105A
Other languages
English (en)
Inventor
John W. Blasecki
Lawrence R. Green
Original Assignee
Cytran, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytran, Ltd. filed Critical Cytran, Ltd.
Publication of HUP9902105A2 publication Critical patent/HUP9902105A2/hu
Publication of HUP9902105A3 publication Critical patent/HUP9902105A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A találmány tárgya R'-Glű-Trp-R'' dipeptid alkalmazása gyógyászatikészítmény előállítására a páciens új érképződését magában főglalópatőlógiás állapőt kezelésére. ŕ
HU9902105A 1995-10-03 1996-10-02 Pharmaceutical angiostatic dipeptide compositions and methods of use thereof HUP9902105A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53870195A 1995-10-03 1995-10-03
US08/614,764 US5902790A (en) 1995-10-03 1996-03-13 Pharmaceutical angiostatic dipeptide compositions and method of use thereof

Publications (2)

Publication Number Publication Date
HUP9902105A2 true HUP9902105A2 (hu) 1999-09-28
HUP9902105A3 HUP9902105A3 (en) 2001-02-28

Family

ID=27065900

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9902105A HUP9902105A3 (en) 1995-10-03 1996-10-02 Pharmaceutical angiostatic dipeptide compositions and methods of use thereof

Country Status (23)

Country Link
US (4) US5902790A (hu)
EP (1) EP0869808B1 (hu)
JP (2) JP3679129B2 (hu)
KR (1) KR100483779B1 (hu)
CN (1) CN1128636C (hu)
AT (1) ATE332702T1 (hu)
AU (1) AU714846B2 (hu)
BR (1) BR9610838A (hu)
CA (1) CA2233457C (hu)
CZ (1) CZ298345B6 (hu)
DE (1) DE69636343T2 (hu)
DK (1) DK0869808T3 (hu)
EA (1) EA001146B1 (hu)
ES (1) ES2268710T3 (hu)
HU (1) HUP9902105A3 (hu)
IL (1) IL123889A0 (hu)
MX (1) MX9802564A (hu)
NO (1) NO326298B1 (hu)
NZ (1) NZ319907A (hu)
PL (1) PL186123B1 (hu)
SK (1) SK283677B6 (hu)
TR (1) TR199800653T1 (hu)
WO (1) WO1997012625A1 (hu)

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US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US6060452A (en) * 1996-03-13 2000-05-09 Cytran, Inc. Analogs of L-Glu-L-Trp having pharmacological activity
WO1999051720A2 (en) * 1998-04-03 1999-10-14 Cytran Ltd. Methods for production of therapeutic cytokines
JP5048201B2 (ja) 2000-08-04 2012-10-17 ディーエムアイ バイオサイエンシズ インコーポレイテッド ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物
AU2002233288B9 (en) * 2001-01-02 2007-08-09 Imtm Gmbh Combined use of Enzyme Inhibitors and Pharmaceutical Preparations thereof for the Treatment and Prophylaxis of Arteriosclerosis, for the Treatment and Prevention of Allergic Reactions of Type I According to the Gell and Coombs Classification, and for the Treatment and Prevention of Dermatological Diseases Associated with FO
DE10100052A1 (de) * 2001-01-02 2002-07-11 Inst Medizintechnologie Magdeb Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
EP2517721A3 (en) 2003-05-15 2013-04-10 DMI Biosciences, Inc. Treatment of T-cell mediated diseases
WO2005016326A2 (en) * 2003-07-11 2005-02-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
CN1867331B (zh) 2003-09-17 2010-05-26 美国政府健康及人类服务部 作为TNF-α调节剂的沙利度胺类似物
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
CA2569204A1 (en) * 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) * 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
AU2008216799A1 (en) * 2007-02-13 2008-08-21 Sciclone Pharmaceuticals, Inc. Method of treating or preventing tissue deterioration, injury or damage due to disease of mucosa
CA2579119C (en) * 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
MX2010002046A (es) * 2007-08-23 2010-05-03 Sciclone Pharmaceuticals Inc Tratamiento de cancer de pulmon.
US8217047B2 (en) 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
DE102008032828A1 (de) * 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
EP2613786A4 (en) 2010-09-07 2013-10-23 Dmi Acquisition Corp TREATMENT OF DISEASES
EP3721884A1 (en) 2011-10-10 2020-10-14 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease with da-dkp (= aspartyl-alanyl diketopiperazine)
MX2014003856A (es) 2011-10-10 2015-01-16 Ampio Pharmaceuticals Inc Dispositivos medicos implantables con tolerancia inmune incrementada y metodos para hacerlos e implantarlos.
EP2771007B1 (en) 2011-10-28 2018-04-04 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds
CN102631464B (zh) * 2012-05-18 2013-07-31 崔新明 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
KR20170045274A (ko) 2014-08-18 2017-04-26 앰피오 파마슈티컬스 인코퍼레이티드 관절 징후의 치료
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9375478B1 (en) 2015-01-30 2016-06-28 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
WO2016209969A1 (en) 2015-06-22 2016-12-29 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
AU2018326835A1 (en) * 2017-08-31 2020-03-26 National University Of Singapore Angio-3 for treatment of retinal angiogenic diseases

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US3997516A (en) * 1974-07-04 1976-12-14 Takeda Chemical Industries, Ltd. Method for protecting guanidino group and restoring the same
US4191753A (en) * 1978-11-06 1980-03-04 University Of Miami Anti-hypertensive peptide analogs
DE3873327D1 (de) * 1987-12-30 1992-09-03 Vsesojuznyj Kardiologitsches Arzneimittelzubereitung zur behandlung des immunmangels.
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GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
SU1642398A1 (ru) * 1988-12-21 1991-04-15 Ростовский медицинский институт Способ лечени синуитов у детей
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
RU1827255C (ru) * 1990-10-22 1993-07-15 Киевский государственный институт усовершенствования врачей Способ лечени туберкулеза легких
JP3068656B2 (ja) * 1991-03-07 2000-07-24 アピ株式会社 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物
WO1992017191A1 (en) * 1991-04-01 1992-10-15 Cytoven Pharmaceutical dipeptide compositions and methods of use thereof
RU2014063C1 (ru) * 1991-04-23 1994-06-15 Сочинский научно-исследовательский институт курортологии и физиотерапии Способ лечения подострых воспалительных заболеваний гениталий
ATE188219T1 (de) * 1991-10-28 2000-01-15 Cytran Ltd Pharmazeutische dipeptid zusammensetzungen und verwendungsmethoden.
WO1995003067A1 (en) * 1993-07-21 1995-02-02 Khavinson Vladimir Khatskelevi Pharmaceutical with immunomodulating activity
CA2172494A1 (en) * 1993-09-24 1995-03-30 Kathleen Elizabeth Rodgers Use of angiotensin ii analogs in tissue repair

Also Published As

Publication number Publication date
EP0869808A1 (en) 1998-10-14
SK42398A3 (en) 1998-10-07
DK0869808T3 (da) 2006-11-13
SK283677B6 (sk) 2003-11-04
WO1997012625A1 (en) 1997-04-10
CA2233457C (en) 2004-08-03
CZ298345B6 (cs) 2007-09-05
CN1128636C (zh) 2003-11-26
US6096713A (en) 2000-08-01
NO981436L (no) 1998-05-19
US20060094665A1 (en) 2006-05-04
KR19990063958A (ko) 1999-07-26
DE69636343D1 (de) 2006-08-24
CZ91398A3 (cs) 1998-11-11
PL186123B1 (pl) 2003-10-31
US6911431B1 (en) 2005-06-28
PL326149A1 (en) 1998-08-31
JPH11504943A (ja) 1999-05-11
ES2268710T3 (es) 2007-03-16
JP2005194287A (ja) 2005-07-21
DE69636343T2 (de) 2007-07-19
AU7254096A (en) 1997-04-28
BR9610838A (pt) 1999-12-21
JP3679129B2 (ja) 2005-08-03
CA2233457A1 (en) 1997-04-10
NO981436D0 (no) 1998-03-30
NO326298B1 (no) 2008-11-03
AU714846B2 (en) 2000-01-13
IL123889A0 (en) 1998-10-30
EA199800357A1 (ru) 1998-10-29
EP0869808B1 (en) 2006-07-12
EA001146B1 (ru) 2000-10-30
NZ319907A (en) 2000-09-29
US5902790A (en) 1999-05-11
ATE332702T1 (de) 2006-08-15
HUP9902105A3 (en) 2001-02-28
CN1198673A (zh) 1998-11-11
KR100483779B1 (ko) 2007-03-02
MX9802564A (es) 1998-11-30
TR199800653T1 (xx) 1998-06-22

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees