SK283677B6 - Použitie dipeptidu R'-Glu-Trp-R'' na liečenie neovaskularizácie - Google Patents

Použitie dipeptidu R'-Glu-Trp-R'' na liečenie neovaskularizácie Download PDF

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Publication number
SK283677B6
SK283677B6 SK423-98A SK42398A SK283677B6 SK 283677 B6 SK283677 B6 SK 283677B6 SK 42398 A SK42398 A SK 42398A SK 283677 B6 SK283677 B6 SK 283677B6
Authority
SK
Slovakia
Prior art keywords
glu
trp
dipeptide
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
SK423-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK42398A3 (en
Inventor
Lawrence R. Green
John W. Blasecki
Original Assignee
Cytran, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytran, Ltd. filed Critical Cytran, Ltd.
Publication of SK42398A3 publication Critical patent/SK42398A3/sk
Publication of SK283677B6 publication Critical patent/SK283677B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
SK423-98A 1995-10-03 1996-10-02 Použitie dipeptidu R'-Glu-Trp-R'' na liečenie neovaskularizácie SK283677B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53870195A 1995-10-03 1995-10-03
US08/614,764 US5902790A (en) 1995-10-03 1996-03-13 Pharmaceutical angiostatic dipeptide compositions and method of use thereof
PCT/US1996/015856 WO1997012625A1 (en) 1995-10-03 1996-10-02 Pharmaceutical angiostatic dipeptide compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
SK42398A3 SK42398A3 (en) 1998-10-07
SK283677B6 true SK283677B6 (sk) 2003-11-04

Family

ID=27065900

Family Applications (1)

Application Number Title Priority Date Filing Date
SK423-98A SK283677B6 (sk) 1995-10-03 1996-10-02 Použitie dipeptidu R'-Glu-Trp-R'' na liečenie neovaskularizácie

Country Status (23)

Country Link
US (4) US5902790A (hu)
EP (1) EP0869808B1 (hu)
JP (2) JP3679129B2 (hu)
KR (1) KR100483779B1 (hu)
CN (1) CN1128636C (hu)
AT (1) ATE332702T1 (hu)
AU (1) AU714846B2 (hu)
BR (1) BR9610838A (hu)
CA (1) CA2233457C (hu)
CZ (1) CZ298345B6 (hu)
DE (1) DE69636343T2 (hu)
DK (1) DK0869808T3 (hu)
EA (1) EA001146B1 (hu)
ES (1) ES2268710T3 (hu)
HU (1) HUP9902105A3 (hu)
IL (1) IL123889A0 (hu)
MX (1) MX9802564A (hu)
NO (1) NO326298B1 (hu)
NZ (1) NZ319907A (hu)
PL (1) PL186123B1 (hu)
SK (1) SK283677B6 (hu)
TR (1) TR199800653T1 (hu)
WO (1) WO1997012625A1 (hu)

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US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
US6060452A (en) * 1996-03-13 2000-05-09 Cytran, Inc. Analogs of L-Glu-L-Trp having pharmacological activity
WO1999051720A2 (en) * 1998-04-03 1999-10-14 Cytran Ltd. Methods for production of therapeutic cytokines
CA2774959C (en) 2000-08-04 2016-05-31 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
DE10100052A1 (de) * 2001-01-02 2002-07-11 Inst Medizintechnologie Magdeb Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose
AU2002233288B9 (en) * 2001-01-02 2007-08-09 Imtm Gmbh Combined use of Enzyme Inhibitors and Pharmaceutical Preparations thereof for the Treatment and Prophylaxis of Arteriosclerosis, for the Treatment and Prevention of Allergic Reactions of Type I According to the Gell and Coombs Classification, and for the Treatment and Prevention of Dermatological Diseases Associated with FO
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
CA2523467C (en) 2003-05-15 2021-10-26 Dmi Biosciences, Inc. Treatment of t-cell mediated diseases
WO2005016326A2 (en) * 2003-07-11 2005-02-24 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
WO2005028436A2 (en) 2003-09-17 2005-03-31 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Thalidomide analogs as tnf-alpha modulators
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
CA2569204A1 (en) * 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) * 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
EP2120986A4 (en) * 2007-02-13 2010-04-07 Sciclone Pharmaceuticals Inc METHOD FOR THE TREATMENT OR PREVENTION OF TISSUE WEAR, INJURY OR DAMAGE CAUSED BY SLEWER DISEASES
CA2579119C (en) 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
US20110189305A1 (en) * 2007-08-23 2011-08-04 Tuthill Cynthia W Treatment of lung cancer
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
DE102008032828A1 (de) * 2008-07-02 2010-01-07 Technische Universität Dresden Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel
WO2012033792A2 (en) 2010-09-07 2012-03-15 Dmi Acquisition Corp. Treatment of diseases
AU2012323305B2 (en) 2011-10-10 2017-07-27 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
MY172699A (en) 2011-10-10 2019-12-10 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
AU2012328605B9 (en) 2011-10-28 2017-08-03 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds
CN102631464B (zh) * 2012-05-18 2013-07-31 崔新明 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
US9956217B2 (en) 2014-08-18 2018-05-01 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9375478B1 (en) 2015-01-30 2016-06-28 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
WO2016209969A1 (en) 2015-06-22 2016-12-29 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
EP3675889A4 (en) 2017-08-31 2021-05-12 Singapore Health Services PTE Ltd ANGIO -3 FOR THE TREATMENT OF ANGIOGENIC RETINAL DISEASES
CN116874557A (zh) * 2023-08-01 2023-10-13 首都医科大学 2-Trp-AA-四氢咔啉-3-羧酸类化合物及其PAF抑制剂的应用

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US4191753A (en) * 1978-11-06 1980-03-04 University Of Miami Anti-hypertensive peptide analogs
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GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
SU1642398A1 (ru) * 1988-12-21 1991-04-15 Ростовский медицинский институт Способ лечени синуитов у детей
US5770576A (en) * 1989-08-30 1998-06-23 Cytran, Inc. Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
US5902790A (en) * 1995-10-03 1999-05-11 Cytran, Inc. Pharmaceutical angiostatic dipeptide compositions and method of use thereof
RU1827255C (ru) * 1990-10-22 1993-07-15 Киевский государственный институт усовершенствования врачей Способ лечени туберкулеза легких
JP3068656B2 (ja) * 1991-03-07 2000-07-24 アピ株式会社 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物
AU668088B2 (en) * 1991-04-01 1996-04-26 Cytran Ltd. Pharmaceutical dipeptide compositions and methods of use thereof
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AU2905092A (en) * 1991-10-28 1993-06-07 Cytoven Pharmaceutical dipeptide compositions and methods of use thereof
AU7392294A (en) * 1993-07-21 1995-02-20 Vladimir Khatskelevich Khavinson Pharmaceutical with immunomodulating activity
DE69435301D1 (de) * 1993-09-24 2010-08-26 Univ Southern California Verwendung von Angiotensin-II-Analogen zur Gewebewiederherstellung

Also Published As

Publication number Publication date
DK0869808T3 (da) 2006-11-13
CZ91398A3 (cs) 1998-11-11
AU714846B2 (en) 2000-01-13
KR19990063958A (ko) 1999-07-26
DE69636343D1 (de) 2006-08-24
US20060094665A1 (en) 2006-05-04
JPH11504943A (ja) 1999-05-11
CZ298345B6 (cs) 2007-09-05
EA199800357A1 (ru) 1998-10-29
SK42398A3 (en) 1998-10-07
US5902790A (en) 1999-05-11
KR100483779B1 (ko) 2007-03-02
JP2005194287A (ja) 2005-07-21
DE69636343T2 (de) 2007-07-19
CA2233457A1 (en) 1997-04-10
HUP9902105A2 (hu) 1999-09-28
EP0869808B1 (en) 2006-07-12
PL186123B1 (pl) 2003-10-31
ES2268710T3 (es) 2007-03-16
EP0869808A1 (en) 1998-10-14
NO981436D0 (no) 1998-03-30
JP3679129B2 (ja) 2005-08-03
NO326298B1 (no) 2008-11-03
MX9802564A (es) 1998-11-30
CA2233457C (en) 2004-08-03
AU7254096A (en) 1997-04-28
US6911431B1 (en) 2005-06-28
US6096713A (en) 2000-08-01
EA001146B1 (ru) 2000-10-30
PL326149A1 (en) 1998-08-31
TR199800653T1 (xx) 1998-06-22
BR9610838A (pt) 1999-12-21
IL123889A0 (en) 1998-10-30
HUP9902105A3 (en) 2001-02-28
NO981436L (no) 1998-05-19
NZ319907A (en) 2000-09-29
CN1128636C (zh) 2003-11-26
ATE332702T1 (de) 2006-08-15
CN1198673A (zh) 1998-11-11
WO1997012625A1 (en) 1997-04-10

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Legal Events

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20101002