US2779780A
(en)
|
1955-03-01 |
1957-01-29 |
Du Pont |
1, 4-diamino-2, 3-dicyano-1, 4-bis (substituted mercapto) butadienes and their preparation
|
US4261989A
(en)
|
1979-02-19 |
1981-04-14 |
Kaken Chemical Co. Ltd. |
Geldanamycin derivatives and antitumor drug
|
US4433059A
(en)
|
1981-09-08 |
1984-02-21 |
Ortho Diagnostic Systems Inc. |
Double antibody conjugate
|
US4444878A
(en)
|
1981-12-21 |
1984-04-24 |
Boston Biomedical Research Institute, Inc. |
Bispecific antibody determinants
|
US4851332A
(en)
|
1985-04-01 |
1989-07-25 |
Sloan-Kettering Institute For Cancer Research |
Choriocarcinoma monoclonal antibodies and antibody panels
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
US5114946A
(en)
|
1987-06-12 |
1992-05-19 |
American Cyanamid Company |
Transdermal delivery of pharmaceuticals
|
US4818541A
(en)
|
1987-08-19 |
1989-04-04 |
Schering Corporation |
Transdermal delivery of enantiomers of phenylpropanolamine
|
JPH021556A
(ja)
|
1988-06-09 |
1990-01-05 |
Snow Brand Milk Prod Co Ltd |
ハイブリッド抗体及びその作製方法
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
AU6290090A
(en)
|
1989-08-29 |
1991-04-08 |
University Of Southampton |
Bi-or trispecific (fab)3 or (fab)4 conjugates
|
US5273743A
(en)
|
1990-03-09 |
1993-12-28 |
Hybritech Incorporated |
Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
|
GB9012995D0
(en)
|
1990-06-11 |
1990-08-01 |
Celltech Ltd |
Multivalent antigen-binding proteins
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
US6511663B1
(en)
|
1991-06-11 |
2003-01-28 |
Celltech R&D Limited |
Tri- and tetra-valent monospecific antigen-binding proteins
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
CA2078539C
(en)
|
1991-09-18 |
2005-08-02 |
Kenya Shitara |
Process for producing humanized chimera antibody
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
AU676150B2
(en)
|
1992-01-23 |
1997-03-06 |
Merck Patent Gmbh |
Monomeric and dimeric antibody-fragment fusion proteins
|
AU675929B2
(en)
|
1992-02-06 |
1997-02-27 |
Curis, Inc. |
Biosynthetic binding protein for cancer marker
|
US5646253A
(en)
|
1994-03-08 |
1997-07-08 |
Memorial Sloan-Kettering Cancer Center |
Recombinant human anti-LK26 antibodies
|
ATE165113T1
(de)
|
1992-05-08 |
1998-05-15 |
Creative Biomolecules Inc |
Mehrwertige chimäre proteine anologe und verfahren zu deren anwendungen
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
EP0672068A4
(en)
|
1992-09-25 |
1997-02-26 |
Commw Scient Ind Res Org |
TARGET MOLECULES BINDING POLYPEPTIDES.
|
GB9221657D0
(en)
|
1992-10-15 |
1992-11-25 |
Scotgen Ltd |
Recombinant bispecific antibodies
|
US5262564A
(en)
|
1992-10-30 |
1993-11-16 |
Octamer, Inc. |
Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents
|
CA2126967A1
(en)
|
1992-11-04 |
1994-05-11 |
Anna M. Wu |
Novel antibody construct
|
GB9323648D0
(en)
|
1992-11-23 |
1994-01-05 |
Zeneca Ltd |
Proteins
|
EP0672142B1
(en)
|
1992-12-04 |
2001-02-28 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
US6476198B1
(en)
|
1993-07-13 |
2002-11-05 |
The Scripps Research Institute |
Multispecific and multivalent antigen-binding polypeptide molecules
|
US5635602A
(en)
|
1993-08-13 |
1997-06-03 |
The Regents Of The University Of California |
Design and synthesis of bispecific DNA-antibody conjugates
|
WO1995009917A1
(en)
|
1993-10-07 |
1995-04-13 |
The Regents Of The University Of California |
Genetically engineered bispecific tetravalent antibodies
|
AU7863794A
(en)
|
1993-11-16 |
1995-06-06 |
Pola Chemical Industries Inc. |
Antihuman tyrosinase monoclonal antibody
|
US5635388A
(en)
|
1994-04-04 |
1997-06-03 |
Genentech, Inc. |
Agonist antibodies against the flk2/flt3 receptor and uses thereof
|
EP1630229B1
(en)
|
1994-04-22 |
2013-04-03 |
THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services |
Melanoma antigens
|
US5786464C1
(en)
|
1994-09-19 |
2012-04-24 |
Gen Hospital Corp |
Overexpression of mammalian and viral proteins
|
WO1996013583A2
(en)
|
1994-10-20 |
1996-05-09 |
Morphosys Gesellschaft Für Proteinoptimierung Mbh |
Targeted hetero-association of recombinant proteins to multi-functional complexes
|
ATE186745T1
(de)
|
1995-01-18 |
1999-12-15 |
Roche Diagnostics Gmbh |
Antikörper gegen cd30, die proteolytische spaltung und abgabe des membrangebundenen cd30 antigens verhindern
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
ATE274064T1
(de)
|
1995-05-23 |
2004-09-15 |
Morphosys Ag |
Multimere proteine
|
CN1173878A
(zh)
|
1995-10-16 |
1998-02-18 |
尤尼利弗公司 |
双功能或双价抗体片段类似物
|
US6083502A
(en)
|
1996-01-05 |
2000-07-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Mesothelium antigen and methods and kits for targeting it
|
DE19608769C1
(de)
|
1996-03-07 |
1997-04-10 |
Univ Eberhard Karls |
Antikörper BV10A4H2
|
DE69730209T2
(de)
|
1996-04-04 |
2005-04-14 |
Unilever N.V. |
Multivalentes und multispezifisches Antigenbindungsprotein
|
US6114148C1
(en)
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
US6365712B1
(en)
|
1996-10-25 |
2002-04-02 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Methods and compositions for inhibiting inflammation and angiogenesis comprising a mammalian CD97 α subunit
|
EP0981548A4
(en)
|
1997-04-30 |
2005-11-23 |
Enzon Inc |
SINGLE CHAIN PROTEINS FIXING ANTIGENS CAPABLE OF GLYCOSYLATION, PRODUCTION AND USES THEREOF
|
US20030207346A1
(en)
|
1997-05-02 |
2003-11-06 |
William R. Arathoon |
Method for making multispecific antibodies having heteromultimeric and common components
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
WO1998056906A1
(en)
|
1997-06-11 |
1998-12-17 |
Thoegersen Hans Christian |
Trimerising module
|
CN1203178C
(zh)
|
1997-10-27 |
2005-05-25 |
尤尼利弗公司 |
多价抗原结合蛋白
|
ES2255194T3
(es)
|
1997-12-01 |
2006-06-16 |
The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services |
Anticuerpos, que incluyen moleculas fv, e inmunoconjugados que presentan una afinidad de enlace elevada para la mesotelina y metodos para su utilizacion.
|
ATE283364T1
(de)
|
1998-01-23 |
2004-12-15 |
Vlaams Interuniv Inst Biotech |
Mehrzweck-antikörperderivate
|
CZ121599A3
(cs)
|
1998-04-09 |
1999-10-13 |
Aventis Pharma Deutschland Gmbh |
Jednořetězcová molekula vázající několik antigenů, způsob její přípravy a léčivo obsahující tuto molekulu
|
DE19819846B4
(de)
|
1998-05-05 |
2016-11-24 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Multivalente Antikörper-Konstrukte
|
GB9812545D0
(en)
|
1998-06-10 |
1998-08-05 |
Celltech Therapeutics Ltd |
Biological products
|
US6803448B1
(en)
|
1998-07-22 |
2004-10-12 |
Vanderbilt University |
GBS toxin receptor
|
ES2207278T3
(es)
|
1998-07-28 |
2004-05-16 |
Micromet Ag |
Heterominicuerpos.
|
US6333396B1
(en)
|
1998-10-20 |
2001-12-25 |
Enzon, Inc. |
Method for targeted delivery of nucleic acids
|
EP1143957A3
(en)
|
1998-12-16 |
2002-02-27 |
Warner-Lambert Company |
Treatment of arthritis with mek inhibitors
|
US6528481B1
(en)
|
1999-02-16 |
2003-03-04 |
The Burnam Institute |
NG2/HM proteoglycan-binding peptides that home to angiogenic vasculature and related methods
|
US7527787B2
(en)
|
2005-10-19 |
2009-05-05 |
Ibc Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
US7534866B2
(en)
|
2005-10-19 |
2009-05-19 |
Ibc Pharmaceuticals, Inc. |
Methods and compositions for generating bioactive assemblies of increased complexity and uses
|
HU230583B1
(hu)
|
1999-08-17 |
2017-02-28 |
Biogen Idec Ma Inc. |
BAFF-receptor (BCMA) alkalmazásai immunszabályozó szerként
|
DE60038252T2
(de)
|
1999-09-30 |
2009-03-19 |
Kyowa Hakko Kogyo Co., Ltd. |
Menschlicher Antikörper gegen Gangliosid GD3 für die Transplantationskomplentarität bestimmende Region und Derivate des Antikörpers gegen das Gangliosid GD3
|
AU2048901A
(en)
|
1999-11-29 |
2001-06-04 |
Trustees Of Columbia University In The City Of New York, The |
Isolation of five novel genes coding for new Fc receptors-type melanoma involved in the pathogenesis of lymphoma/melanoma
|
AU784634B2
(en)
|
1999-11-30 |
2006-05-18 |
Mayo Foundation For Medical Education And Research |
B7-H1, a novel immunoregulatory molecule
|
GB0000313D0
(en)
|
2000-01-10 |
2000-03-01 |
Astrazeneca Uk Ltd |
Formulation
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
CA2895884C
(en)
|
2000-03-06 |
2019-04-23 |
University Of Kentucky Research Foundation |
A compound that selectively binds to cd123 and use thereof to kill hematologic cancer progenitor cells
|
AU4761601A
(en)
|
2000-04-11 |
2001-10-23 |
Genentech Inc |
Multivalent antibodies and uses therefor
|
WO2001090192A2
(en)
|
2000-05-24 |
2001-11-29 |
Imclone Systems Incorporated |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
AU2001270609A1
(en)
|
2000-06-30 |
2002-01-14 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Heterodimeric fusion proteins
|
EA005818B1
(ru)
|
2000-07-19 |
2005-06-30 |
Уорнер-Ламберт Компани |
Сложные эфиры фениламинобензгидроксамовых кислот
|
CN1461344A
(zh)
|
2000-07-25 |
2003-12-10 |
免疫医疗公司 |
多价靶结合蛋白
|
GB0020685D0
(en)
|
2000-08-22 |
2000-10-11 |
Novartis Ag |
Organic compounds
|
CN1308447C
(zh)
|
2000-10-20 |
2007-04-04 |
中外制药株式会社 |
低分子化的激动剂抗体
|
US7090843B1
(en)
|
2000-11-28 |
2006-08-15 |
Seattle Genetics, Inc. |
Recombinant anti-CD30 antibodies and uses thereof
|
US6995162B2
(en)
|
2001-01-12 |
2006-02-07 |
Amgen Inc. |
Substituted alkylamine derivatives and methods of use
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
WO2002072635A2
(en)
|
2001-03-13 |
2002-09-19 |
University College London |
Specific binding members
|
CN1294148C
(zh)
|
2001-04-11 |
2007-01-10 |
中国科学院遗传与发育生物学研究所 |
环状单链三特异抗体
|
US6770622B2
(en)
|
2001-06-08 |
2004-08-03 |
Gary A. Jarvis |
N-terminally truncated galectin-3 for use in treating cancer
|
DK1399484T3
(da)
|
2001-06-28 |
2010-11-08 |
Domantis Ltd |
Dobbelt-specifik ligand og anvendelse af denne
|
US6833441B2
(en)
|
2001-08-01 |
2004-12-21 |
Abmaxis, Inc. |
Compositions and methods for generating chimeric heteromultimers
|
CN103224562B
(zh)
|
2001-08-23 |
2017-09-08 |
Rsr有限公司 |
促甲状腺素受体的表位区域和针对该区域的抗体
|
ES2276735T3
(es)
|
2001-09-14 |
2007-07-01 |
Affimed Therapeutics Ag |
Anticuerpos fv multimericos de cadena sencilla en tandem.
|
JP4716350B2
(ja)
|
2001-12-04 |
2011-07-06 |
ダナ−ファーバー キャンサー インスティテュート インク. |
潜伏期膜タンパク質に対する抗体およびそれらの使用
|
US20030211078A1
(en)
|
2001-12-07 |
2003-11-13 |
Heavner George A. |
Pseudo-antibody constructs
|
EA008379B1
(ru)
|
2002-02-01 |
2007-04-27 |
Ариад Джин Терапьютикс, Инк. |
Фосфорсодержащие соединения и их применения
|
AU2003209446B2
(en)
|
2002-03-01 |
2008-09-25 |
Immunomedics, Inc. |
Bispecific antibody point mutations for enhancing rate of clearance
|
RU2334744C2
(ru)
|
2002-03-08 |
2008-09-27 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Макроциклические соединения, которые могут быть использованы в качестве фармацевтических препаратов
|
KR100984613B1
(ko)
|
2002-03-13 |
2010-09-30 |
어레이 바이오파마 인크. |
Mek 억제제로서의 n3 알킬화 벤즈이미다졸 유도체
|
JP4386741B2
(ja)
|
2002-04-15 |
2009-12-16 |
中外製薬株式会社 |
scDbライブラリーの作成方法
|
TWI275390B
(en)
|
2002-04-30 |
2007-03-11 |
Wyeth Corp |
Process for the preparation of 7-substituted-3- quinolinecarbonitriles
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
EP3287144A1
(en)
|
2002-07-03 |
2018-02-28 |
ONO Pharmaceutical Co., Ltd. |
Immunopotentiating compositions
|
GB0215823D0
(en)
|
2002-07-09 |
2002-08-14 |
Astrazeneca Ab |
Quinazoline derivatives
|
ES2318167T3
(es)
|
2002-07-15 |
2009-05-01 |
The Trustees Of Princeton University |
Compuestos de union a iap.
|
AU2003291002A1
(en)
|
2002-11-15 |
2004-06-15 |
Chiron Corporation |
Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasis
|
DE50306067D1
(de)
|
2002-11-26 |
2007-02-01 |
Brahms Ag |
Nachweis von tsh-rezeptor-autoantikörpern mit affinitätsgereinigten antikörpern
|
JP4511943B2
(ja)
|
2002-12-23 |
2010-07-28 |
ワイス エルエルシー |
Pd−1に対する抗体およびその使用
|
AU2003292625B2
(en)
|
2002-12-26 |
2008-07-24 |
Eisai R & D Management Co., Ltd. |
Selective estrogen receptor modulators
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
GB0305702D0
(en)
|
2003-03-12 |
2003-04-16 |
Univ Birmingham |
Bispecific antibodies
|
WO2004087758A2
(en)
|
2003-03-26 |
2004-10-14 |
Neopharm, Inc. |
Il 13 receptor alpha 2 antibody and methods of use
|
US20050003403A1
(en)
|
2003-04-22 |
2005-01-06 |
Rossi Edmund A. |
Polyvalent protein complex
|
CU23403A1
(es)
|
2003-04-23 |
2009-08-04 |
Centro Inmunologia Molecular |
Anticuerpos recombinantes y fragmentos que reconocen el gangliósido n-glicolil gm3 y su uso para diagnóstico y tratamiento de tumores
|
AU2004252171B2
(en)
|
2003-06-27 |
2011-04-21 |
Biogen Ma Inc. |
Modified binding molecules comprising connecting peptides
|
CA2530605A1
(en)
|
2003-06-27 |
2005-05-26 |
Diadexus, Inc. |
Pro104 antibody compositions and methods of use
|
EP1638510B1
(en)
|
2003-07-01 |
2015-09-02 |
Immunomedics, Inc. |
Multivalent carriers of bi-specific antibodies
|
US7696322B2
(en)
|
2003-07-28 |
2010-04-13 |
Catalent Pharma Solutions, Inc. |
Fusion antibodies
|
AU2004263514A1
(en)
|
2003-08-05 |
2005-02-17 |
Morphotek, Inc. |
A variant cell surface molecule associated with cancer
|
US7399865B2
(en)
|
2003-09-15 |
2008-07-15 |
Wyeth |
Protein tyrosine kinase enzyme inhibitors
|
JPWO2005035577A1
(ja)
|
2003-10-08 |
2007-11-22 |
協和醗酵工業株式会社 |
ガングリオシドgd3に特異的に結合する抗体組成物
|
AU2004279742A1
(en)
|
2003-10-08 |
2005-04-21 |
Kyowa Hakko Kirin Co., Ltd. |
Fused protein composition
|
US7435596B2
(en)
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
US20050136051A1
(en)
|
2003-12-22 |
2005-06-23 |
Bernard Scallon |
Methods for generating multimeric molecules
|
GB0329825D0
(en)
|
2003-12-23 |
2004-01-28 |
Celltech R&D Ltd |
Biological products
|
US20050266425A1
(en)
|
2003-12-31 |
2005-12-01 |
Vaccinex, Inc. |
Methods for producing and identifying multispecific antibodies
|
MXPA06007856A
(es)
|
2004-01-07 |
2007-03-23 |
Chiron Corp |
Anticuerpo monoclonal especifico de factor de estimulacion de colonias de macrofagos (m-csf) y usos del mismo.
|
CA2553874A1
(en)
|
2004-01-16 |
2005-08-04 |
The Regents Of The University Of Michigan |
Conformationally constrained smac mimetics and the uses thereof
|
EP1715882A4
(en)
|
2004-01-16 |
2009-04-08 |
Univ Michigan |
SMAC-PEPTIDOMIMETIKA AND ITS USES
|
US8383575B2
(en)
|
2004-01-30 |
2013-02-26 |
Paul Scherrer Institut |
(DI)barnase-barstar complexes
|
MXPA06008700A
(es)
|
2004-02-06 |
2007-01-19 |
Morphosys Ag |
Anticuerpos anti-cd38 humanos y usos para los mismos.
|
US7345081B2
(en)
|
2004-03-23 |
2008-03-18 |
Genentech, Inc. |
Azabicyclo-octane inhibitors of IAP
|
ME02125B
(me)
|
2004-04-07 |
2013-04-30 |
Novartis Ag |
Inhibitori protein apoptoze (iap)
|
AU2005249490B2
(en)
|
2004-06-01 |
2010-07-29 |
Genentech, Inc. |
Antibody drug conjugates and methods
|
DK2298768T3
(da)
|
2004-06-11 |
2013-01-02 |
Japan Tobacco Inc |
5-Amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2H-pyrido[2,3-d]pyrimidinderivater og beslægtede forbindelser til behandling af cancer
|
CN101035802A
(zh)
|
2004-07-02 |
2007-09-12 |
健泰科生物技术公司 |
Iap抑制剂
|
WO2006010118A2
(en)
|
2004-07-09 |
2006-01-26 |
The Regents Of The University Of Michigan |
Conformationally constrained smac mimetics and the uses thereof
|
AU2005271831A1
(en)
|
2004-07-12 |
2006-02-16 |
Idun Pharmaceuticals, Inc. |
Tetrapeptide analogs
|
JP5230865B2
(ja)
|
2004-07-15 |
2013-07-10 |
テトラロジック ファーマシューティカルズ コーポレーション |
Iap結合性化合物
|
EP1786918A4
(en)
|
2004-07-17 |
2009-02-11 |
Imclone Systems Inc |
NEW BISPECIFIC ANTIBODY TETRAVALENT
|
WO2006028936A2
(en)
|
2004-09-02 |
2006-03-16 |
Genentech, Inc. |
Heteromultimeric molecules
|
US7999077B2
(en)
|
2004-09-30 |
2011-08-16 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
IRTA2 antibodies and methods of use
|
PT1802291E
(pt)
|
2004-10-04 |
2012-03-12 |
Univ Minnesota |
Miméticos conformacionais de péptidos à base de calixareno, métodos de utilização e métodos de preparação
|
ZA200704910B
(en)
|
2004-12-20 |
2008-09-25 |
Genentech Inc |
Pyrrolidine inhibitors of IAP
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
CA2594318A1
(en)
|
2005-01-12 |
2006-07-20 |
Medarex, Inc. |
Irta-2 antibodies and their uses
|
SI1850873T1
(sl)
|
2005-02-08 |
2019-05-31 |
Genzyme Corporation |
Protitelesa proti TGFBETA
|
ES2386367T3
(es)
|
2005-03-10 |
2012-08-17 |
Morphotek, Inc. |
Anticuerpos anti-mesotelina
|
JP5238936B2
(ja)
|
2005-03-25 |
2013-07-17 |
ジーアイティーアール,インク. |
Gitr結合分子およびその使用
|
AU2006232287B2
(en)
|
2005-03-31 |
2011-10-06 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for producing polypeptides by regulating polypeptide association
|
EP1874824A4
(en)
|
2005-04-06 |
2009-12-30 |
Ibc Pharmaceuticals Inc |
METHODS OF GENERATING STABLE COMPOUND RELATED COMPLEXES OF HOMODIMERS, HOMOTRATEERS OR DIMER SIZES AND USES THEREOF
|
AU2006236439B2
(en)
|
2005-04-15 |
2012-05-03 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
KR101339628B1
(ko)
|
2005-05-09 |
2013-12-09 |
메다렉스, 인코포레이티드 |
예정 사멸 인자 1(pd-1)에 대한 인간 모노클로날 항체, 및 항-pd-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
|
US20060263367A1
(en)
|
2005-05-23 |
2006-11-23 |
Fey Georg H |
Bispecific antibody devoid of Fc region and method of treatment using same
|
EP1726650A1
(en)
|
2005-05-27 |
2006-11-29 |
Universitätsklinikum Freiburg |
Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
|
US20060286103A1
(en)
|
2005-06-15 |
2006-12-21 |
Parag Kolhe |
Stable antibody formulation
|
DK1907424T3
(en)
|
2005-07-01 |
2015-11-09 |
Squibb & Sons Llc |
HUMAN MONOCLONAL ANTIBODIES TO PROGRAMMED death ligand 1 (PD-L1)
|
WO2007004415A1
(ja)
|
2005-07-01 |
2007-01-11 |
Murata Manufacturing Co., Ltd. |
多層セラミック基板およびその製造方法ならびに多層セラミック基板作製用複合グリーンシート
|
CN101213474B
(zh)
|
2005-07-04 |
2012-06-13 |
株式会社尼康美景 |
距离测量设备
|
EP1912636B1
(en)
|
2005-07-21 |
2014-06-25 |
Ardea Biosciences, Inc. |
N-(arylamino)-sulfonamide inhibitors of mek
|
SG2014010029A
(en)
|
2005-08-19 |
2014-08-28 |
Abbott Lab |
Dual variable domain immunoglobin and uses thereof
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
EP1757622B1
(en)
|
2005-08-26 |
2009-12-23 |
PLS Design GmbH |
Bivalent IgY antibody constructs for diagnostic and therapeutic applications
|
WO2007044887A2
(en)
|
2005-10-11 |
2007-04-19 |
Transtarget, Inc. |
Method for producing a population of homogenous tetravalent bispecific antibodies
|
WO2007062466A1
(en)
|
2005-11-29 |
2007-06-07 |
The University Of Sydney |
Demibodies: dimerisation-activated therapeutic agents
|
AU2006321554B2
(en)
|
2005-12-08 |
2012-08-02 |
E. R. Squibb & Sons, L.L.C. |
Human monoclonal antibodies to Fucosyl-GM1 and methods for using anti-Fucosyl-GM1
|
EP1806365A1
(en)
|
2006-01-05 |
2007-07-11 |
Boehringer Ingelheim International GmbH |
Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them
|
WO2007084342A2
(en)
|
2006-01-13 |
2007-07-26 |
The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health |
Codon optimi zed il- 15 and il- 15r-alpha genes for expression in mammalian cells
|
AU2007215013A1
(en)
|
2006-02-15 |
2007-08-23 |
Imclone Systems Incorporated |
Functional antibodies
|
GEP20135917B
(en)
|
2006-03-17 |
2013-09-10 |
Biogen Idec Inc |
Stabilized polypeptide compositions
|
ATE509033T1
(de)
|
2006-03-20 |
2011-05-15 |
Univ California |
Manipulierte anti-prostatastammzellenantigen (psca)-antikörper für krebs-targeting
|
US8946391B2
(en)
|
2006-03-24 |
2015-02-03 |
The Regents Of The University Of California |
Construction of a multivalent scFv through alkyne-azide 1,3-dipolar cycloaddition
|
CA2646965C
(en)
|
2006-03-24 |
2016-06-21 |
Jonathan H. Davis |
Engineered heterodimeric protein domains
|
ES2482145T3
(es)
|
2006-03-29 |
2014-08-01 |
King's College London |
Anticuerpos agonistas contra TSHR
|
ES2654040T3
(es)
|
2006-03-31 |
2018-02-12 |
Chugai Seiyaku Kabushiki Kaisha |
Método de modificación de anticuerpos para la purificación de anticuerpos biespecíficos
|
RS56600B1
(sr)
|
2006-04-19 |
2018-02-28 |
Novartis Ag |
6-o-supstituisana jedinjenja benzoksazola i benzotiazola i postupci inhibicije csf-1r signalinga
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之c-kit抗體
|
WO2007131092A2
(en)
|
2006-05-03 |
2007-11-15 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Chimeric t cell receptors and related materials and methods of use
|
WO2008011216A2
(en)
|
2006-05-16 |
2008-01-24 |
Pro-Pharmaceuticals, Inc. |
Galactose-pronged polysaccharides in a formulation for antifibrotic therapies
|
EP2799449A1
(en)
|
2006-05-25 |
2014-11-05 |
Bayer Intellectual Property GmbH |
Dimeric molecular complexes
|
US20070274985A1
(en)
|
2006-05-26 |
2007-11-29 |
Stefan Dubel |
Antibody
|
CN105837690A
(zh)
|
2006-06-12 |
2016-08-10 |
新兴产品开发西雅图有限公司 |
具有效应功能的单链多价结合蛋白
|
CA2661042C
(en)
|
2006-08-18 |
2012-12-11 |
Armagen Technologies, Inc. |
Agents for blood-brain barrier delivery
|
MX2009001878A
(es)
|
2006-08-21 |
2009-03-03 |
Genentech Inc |
Compuestos de aza-benzofuranilo y metodos de uso.
|
US8877780B2
(en)
|
2006-08-30 |
2014-11-04 |
Celgene Corporation |
5-substituted isoindoline compounds
|
DK2059533T3
(da)
|
2006-08-30 |
2013-02-25 |
Genentech Inc |
Multispecifikke antistoffer
|
EP2083868A2
(en)
|
2006-10-04 |
2009-08-05 |
Københavns Universitet |
Generation of a cancer-specific immune response toward muc1 and cancer specific muc1 antibodies
|
FR2906808B1
(fr)
|
2006-10-10 |
2012-10-05 |
Univ Nantes |
Utilisation d'anticorps monoclonaux specifiques de la forme o-acetylee du ganglioside gd2 dans le traitement de certains cancers
|
DK3284825T3
(da)
|
2006-11-02 |
2021-05-25 |
Biomolecular Holdings Llc |
Fremgangsmåder til at fremstille hybride polypeptider med bevægelige dele
|
ME01507B
(me)
|
2006-11-22 |
2014-04-20 |
Incyte Holdings Corp |
Imidazotriazini i imidazopirimidini kao inhibitori kinaze
|
MX2009005358A
(es)
|
2006-11-23 |
2009-06-05 |
Novartis Ag |
Derivados de 5-sulfanilmetil-pirazolo[1,5-a]pirimidin-7-ol como antagonistas de cxcr2.
|
MX2009005174A
(es)
|
2006-11-23 |
2009-05-25 |
Novartis Ag |
Derivados de 5-sulfanilmetil-[1,2,4]triazol[1,5-a]pirimidin-7-ol como antagonistas de cxcr2.
|
KR20090086080A
(ko)
|
2006-11-23 |
2009-08-10 |
노파르티스 아게 |
피리미딘 및 그의 cxcr2 수용체 길항제로서의 용도
|
WO2008101234A2
(en)
|
2007-02-16 |
2008-08-21 |
Sloan-Kettering Institute For Cancer Research |
Anti ganglioside gd3 antibodies and uses thereof
|
US7635753B2
(en)
|
2007-02-19 |
2009-12-22 |
Wisconsin Alumni Research Foundation |
Prostate cancer and melanoma antigens
|
CA2682093A1
(en)
|
2007-03-29 |
2008-10-09 |
Technion Research & Development Foundation Ltd. |
Antibodies, methods and kits for diagnosing and treating melanoma
|
ES2667863T3
(es)
|
2007-03-29 |
2018-05-14 |
Genmab A/S |
Anticuerpos biespecíficos y métodos de producción de los mismos
|
WO2008127735A1
(en)
|
2007-04-13 |
2008-10-23 |
Stemline Therapeutics, Inc. |
Il3ralpha antibody conjugates and uses thereof
|
CA2682605A1
(en)
|
2007-04-18 |
2008-10-30 |
Zymogenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
CN101687787A
(zh)
|
2007-04-30 |
2010-03-31 |
健泰科生物技术公司 |
Iap的抑制剂
|
US9244059B2
(en)
|
2007-04-30 |
2016-01-26 |
Immutep Parc Club Orsay |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
AU2008253720B2
(en)
|
2007-05-11 |
2014-01-16 |
Altor Bioscience Corporation |
Fusion molecules and IL-15 variants
|
JP2010190572A
(ja)
|
2007-06-01 |
2010-09-02 |
Sapporo Medical Univ |
IL13Ra2に対する抗体およびこれを含む診断・治療薬
|
BRPI0812913B8
(pt)
|
2007-06-18 |
2021-05-25 |
Merck Sharp & Dohme |
anticorpos monoclonais ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotideo, método para produzir os referidos anticorpos ou fragmentos de anticorpos, composição que os compreende e uso dos mesmos
|
AU2008282863A1
(en)
|
2007-07-31 |
2009-02-05 |
Merck Sharp & Dohme Corp. |
IGF-1R specific antibodies useful in the detection and diagnosis of cellular proliferative disorders
|
EP2069401A4
(en)
|
2007-07-31 |
2011-02-23 |
Medimmune Llc |
MULTISPECIENT EPITOP BINDING PROTEINS AND THEIR USE
|
EP2532676B1
(en)
|
2007-08-15 |
2017-03-22 |
Bayer Pharma Aktiengesellschaft |
Protease-regulated antibody
|
US8247397B2
(en)
|
2007-09-12 |
2012-08-21 |
Genentech, Inc. |
Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use
|
CN101951946B
(zh)
|
2007-10-01 |
2014-12-10 |
百时美施贵宝公司 |
结合间皮素的人抗体及其应用
|
EP2044949A1
(en)
|
2007-10-05 |
2009-04-08 |
Immutep |
Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
|
EP2214675B1
(en)
|
2007-10-25 |
2013-11-20 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
CA2706529C
(en)
|
2007-11-26 |
2016-10-25 |
Bayer Schering Pharma Aktiengesellschaft |
Anti-mesothelin antibodies and uses therefor
|
US20110053865A1
(en)
|
2007-11-27 |
2011-03-03 |
Ablynx N.V. |
Amino acid sequences directed against heterodimeric cytokines and/or their receptors and polypeptides comprising the same
|
MX2010005927A
(es)
|
2007-11-30 |
2010-06-15 |
Glaxo Group Ltd |
Construcciones de union de antigenos.
|
PE20131210A1
(es)
|
2007-12-19 |
2013-10-31 |
Genentech Inc |
Derivados de 5-anilinoimidazopiridina como inhibidores de mek
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
US8242247B2
(en)
|
2007-12-21 |
2012-08-14 |
Hoffmann-La Roche Inc. |
Bivalent, bispecific antibodies
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
US8227577B2
(en)
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
WO2009089004A1
(en)
|
2008-01-07 |
2009-07-16 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
RU2531758C2
(ru)
|
2008-02-11 |
2014-10-27 |
Куретек Лтд. |
Моноклональные антитела для лечения опухолей
|
WO2009106539A1
(en)
|
2008-02-26 |
2009-09-03 |
Novartis Ag |
Heterocyclic compounds as inhibitors of cxcr2
|
US8168757B2
(en)
|
2008-03-12 |
2012-05-01 |
Merck Sharp & Dohme Corp. |
PD-1 binding proteins
|
AR071891A1
(es)
|
2008-05-30 |
2010-07-21 |
Imclone Llc |
Anticuerpos humanos anti-flt3 (receptor tirosina cinasa 3 tipo fms humano)
|
US8168784B2
(en)
|
2008-06-20 |
2012-05-01 |
Abbott Laboratories |
Processes to make apoptosis promoters
|
GB0906579D0
(en)
|
2009-04-16 |
2009-05-20 |
Vernalis R&D Ltd |
Pharmaceuticals, compositions and methods of making and using the same
|
UA103198C2
(en)
|
2008-08-04 |
2013-09-25 |
Новартис Аг |
Squaramide derivatives as cxcr2 antagonists
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
EP2331547B1
(en)
|
2008-08-22 |
2014-07-30 |
Novartis AG |
Pyrrolopyrimidine compounds as cdk inhibitors
|
EA023148B1
(ru)
|
2008-08-25 |
2016-04-29 |
Эмплиммьюн, Инк. |
Композиции на основе антагонистов pd-1 и их применение
|
CA2735006A1
(en)
|
2008-08-25 |
2010-03-11 |
Amplimmune, Inc. |
Pd-1 antagonists and methods of use thereof
|
JP2012501670A
(ja)
|
2008-09-12 |
2012-01-26 |
アイシス・イノベーション・リミテッド |
Pd−1特異抗体およびその使用
|
AU2009293007B2
(en)
|
2008-09-19 |
2015-10-08 |
University Of Pittsburgh-Of The Commonwealth System Of Higher Education |
Monoclonal antibodies for cspg4 for the diagnosis and treatment of basal breast carcinoma
|
ES2592216T3
(es)
|
2008-09-26 |
2016-11-28 |
Dana-Farber Cancer Institute, Inc. |
Anticuerpos anti-PD-1, PD-L1 y PD-L2 humanos y sus usos
|
WO2010063802A1
(en)
|
2008-12-05 |
2010-06-10 |
Novartis Ag |
3, 4-di-substituted cyclobutene- 1, 2 -diones as cxcr2 receptor antagonists
|
CN114835812A
(zh)
|
2008-12-09 |
2022-08-02 |
霍夫曼-拉罗奇有限公司 |
抗-pd-l1抗体及它们用于增强t细胞功能的用途
|
EP2210891A1
(en)
|
2009-01-26 |
2010-07-28 |
Domain Therapeutics |
New adenosine receptor ligands and uses thereof
|
JP5844159B2
(ja)
|
2009-02-09 |
2016-01-13 |
ユニヴェルシテ デクス−マルセイユUniversite D’Aix−Marseille |
Pd−1抗体およびpd−l1抗体ならびにその使用
|
US9133197B2
(en)
|
2009-03-20 |
2015-09-15 |
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. |
Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments
|
RU2587621C2
(ru)
|
2009-04-01 |
2016-06-20 |
Дженентек, Инк. |
АНТИТЕЛА К FcRH5, ИХ ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
TW201039846A
(en)
|
2009-04-01 |
2010-11-16 |
Genentech Inc |
Anti-FcRH5 antibodies and immunoconjugates and methods of use
|
US9067986B2
(en)
|
2009-04-27 |
2015-06-30 |
Oncomed Pharmaceuticals, Inc. |
Method for making heteromultimeric molecules
|
EP2426148B1
(en)
|
2009-04-27 |
2015-08-05 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-il-3ra antibody for use in treatment of blood tumor
|
TWI445708B
(zh)
|
2009-09-02 |
2014-07-21 |
Irm Llc |
作為tlr活性調節劑之化合物及組合物
|
PT3023438T
(pt)
|
2009-09-03 |
2020-05-08 |
Merck Sharp & Dohme |
Anticorpos anti-gitr
|
HUE049647T2
(hu)
|
2009-11-24 |
2020-09-28 |
Medimmune Ltd |
Targetált kötõdõ ágensek B7-H1 ellen
|
JP2013512251A
(ja)
|
2009-11-24 |
2013-04-11 |
アンプリミューン、インコーポレーテッド |
Pd−l1/pd−l2の同時阻害
|
AU2010325969B2
(en)
|
2009-12-02 |
2016-10-20 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
WO2011076922A1
(en)
|
2009-12-23 |
2011-06-30 |
Synimmune Gmbh |
Anti-flt3 antibodies and methods of using the same
|
BR112012019540B1
(pt)
|
2010-02-05 |
2021-09-28 |
Heptares Therapeutics Limited |
Composto, uso de um composto, formulação farmacêutica, e, processo para a preparação de um composto
|
MX340437B
(es)
|
2010-02-24 |
2016-07-08 |
Immunogen Inc |
Anticuerpos e inmunoconjugados del receptor 1 de folato y usos de los mismos.
|
EP2545078A1
(en)
|
2010-03-11 |
2013-01-16 |
UCB Pharma, S.A. |
Pd-1 antibody
|
ES2365960B1
(es)
|
2010-03-31 |
2012-06-04 |
Palobiofarma, S.L |
Nuevos antagonistas de los receptores de adenosina.
|
MX353144B
(es)
|
2010-04-20 |
2017-12-20 |
Genmab As |
Proteinas que contienen fc de anticuerpos heterodimericos y metodos para produccion de las mismas.
|
DK2580210T5
(en)
|
2010-06-10 |
2017-06-19 |
Seragon Pharmaceuticals Inc |
ESTROGEN RECEPTOR MODULATORS AND APPLICATIONS THEREOF
|
CA2814155C
(en)
|
2010-06-11 |
2019-10-22 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-tim-3 antibody
|
WO2011159847A2
(en)
|
2010-06-15 |
2011-12-22 |
The Regents Of The University Of California |
Receptor tyrosine kinase-like orphan receptor 1 (ror1) single chain fv antibody fragment conjugates and methods of use thereof
|
US8853423B2
(en)
|
2010-06-17 |
2014-10-07 |
Seragon Pharmaceuticals, Inc. |
Indane estrogen receptor modulators and uses thereof
|
CA2802344C
(en)
|
2010-06-18 |
2023-06-13 |
The Brigham And Women's Hospital, Inc. |
Bi-specific antibodies against tim-3 and pd-1 for immunotherapy in chronic immune conditions
|
EP2582722A4
(en)
|
2010-06-19 |
2013-12-18 |
Sloan Kettering Inst Cancer |
ANTIBODIES AGAINST GD2
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
EP2614143B1
(en)
|
2010-09-08 |
2018-11-07 |
Baylor College Of Medicine |
Immunotherapy of non-small lung cancer using genetically engineered gd2-specific t cells
|
GB2483736B
(en)
|
2010-09-16 |
2012-08-29 |
Aragon Pharmaceuticals Inc |
Estrogen receptor modulators and uses thereof
|
JP5933573B2
(ja)
|
2010-11-08 |
2016-06-15 |
ノバルティス アーゲー |
Cxcr2結合ポリペプチド
|
PT3214091T
(pt)
|
2010-12-09 |
2019-01-11 |
Univ Pennsylvania |
Utilização de células t modificadas por recetor de antigénio quimérico para tratar o cancro
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
ES2651510T3
(es)
|
2011-04-01 |
2018-01-26 |
Memorial Sloan-Kettering Cancer Center |
Anticuerpos similares a receptores de células T específicos para un péptido de WT1 presentado por HLA-A2
|
RU2625034C2
(ru)
|
2011-04-20 |
2017-07-11 |
МЕДИММЬЮН, ЭлЭлСи |
Антитела и другие молекулы, которые связывают в7-н1 и pd-1
|
AR086044A1
(es)
|
2011-05-12 |
2013-11-13 |
Imclone Llc |
Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos
|
MX351069B
(es)
|
2011-05-27 |
2017-09-29 |
Glaxo Group Ltd |
Proteinas de union abcma (cd269/tnfrsf17).
|
DK2714735T3
(da)
|
2011-06-03 |
2021-10-18 |
Xoma Technology Ltd |
Antistoffer, der er specifikke for TGF-beta
|
EP2537933A1
(en)
|
2011-06-24 |
2012-12-26 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
An IL-15 and IL-15Ralpha sushi domain based immunocytokines
|
WO2013006490A2
(en)
|
2011-07-01 |
2013-01-10 |
Cellerant Therapeutics, Inc. |
Antibodies that specifically bind to tim3
|
KR20190133790A
(ko)
|
2011-08-01 |
2019-12-03 |
제넨테크, 인크. |
Pd-1 축 결합 길항제 및 mek 억제제를 사용하는 암 치료 방법
|
HUE035751T2
(hu)
|
2011-09-02 |
2018-08-28 |
Novartis Ag |
Gyulladásgátló szubsztituált ciklobuténdion vegyület kolinsó
|
EA201490636A1
(ru)
|
2011-09-16 |
2014-08-29 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Сконструированные с помощью рнк t-клетки для лечения злокачественных новообразований
|
WO2013040371A2
(en)
|
2011-09-16 |
2013-03-21 |
Baylor College Of Medicine |
Targeting the tumor microenvironment using manipulated nkt cells
|
ITMO20110270A1
(it)
|
2011-10-25 |
2013-04-26 |
Sara Caldrer |
Una cellula effettrice modificata per il trattamento di neoplasie esprimenti il disialonganglioside gd2
|
RS59166B1
(sr)
|
2011-10-27 |
2019-10-31 |
Genmab As |
Proizvodnja heterodimernih proteina
|
WO2013063419A2
(en)
|
2011-10-28 |
2013-05-02 |
The Trustees Of The University Of Pennsylvania |
A fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
US10391126B2
(en)
|
2011-11-18 |
2019-08-27 |
Board Of Regents, The University Of Texas System |
CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA
|
SG11201402603WA
(en)
|
2011-11-28 |
2014-06-27 |
Merck Patent Gmbh |
Anti-pd-l1 antibodies and uses thereof
|
US9439768B2
(en)
|
2011-12-08 |
2016-09-13 |
Imds Llc |
Glenoid vault fixation
|
JO3357B1
(ar)
|
2012-01-26 |
2019-03-13 |
Novartis Ag |
مركبات إيميدازوبيروليدينون
|
EP2814846B1
(en)
|
2012-02-13 |
2020-01-08 |
Seattle Children's Hospital d/b/a Seattle Children's Research Institute |
Bispecific chimeric antigen receptors and therapeutic uses thereof
|
JP2015513399A
(ja)
|
2012-02-22 |
2015-05-14 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
癌の治療のために有用なt細胞の存続的集団を作製するための組成物および方法
|
US9359447B2
(en)
|
2012-03-23 |
2016-06-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
EP2844300B1
(en)
|
2012-05-01 |
2018-10-17 |
Genentech, Inc. |
Anti-pmel17 antibodies and immunoconjugates
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
EP4053162A1
(en)
|
2012-05-18 |
2022-09-07 |
Aptevo Research and Development LLC |
Bispecific scfv immunofusion (bif) binding to cd123 and cd3
|
WO2013179174A1
(en)
|
2012-05-29 |
2013-12-05 |
Koninklijke Philips N.V. |
Lighting arrangement
|
KR102284247B1
(ko)
|
2012-05-31 |
2021-08-03 |
소렌토 쎄라퓨틱스, 인코포레이티드 |
Pd-l1에 결합하는 항원 결합 단백질
|
WO2013192294A1
(en)
|
2012-06-20 |
2013-12-27 |
Boston 3T Biotechnologies, Inc. |
Cellular therapies for treating and preventing cancers and other immune system disorders
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
EP2890715B1
(en)
|
2012-08-03 |
2020-12-16 |
Dana-Farber Cancer Institute, Inc. |
Single agent anti-pd-l1 and pd-l2 dual binding antibodies and methods of use
|
PT2884999T
(pt)
|
2012-08-20 |
2021-01-05 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Método e composições para imunoterapêutica celular
|
DK2900061T3
(da)
|
2012-09-17 |
2020-03-02 |
Galectin Therapeutics Inc |
Fremgangsmåde til forstærkning af specifikke immunterapier ved cancerbehandling
|
CA3139031A1
(en)
|
2012-10-04 |
2014-04-10 |
Dana-Farber Cancer Institute, Inc. |
Human monoclonal anti-pd-l1 antibodies and methods of use
|
AU2013334610B2
(en)
|
2012-10-24 |
2018-09-13 |
Novartis Ag |
IL-15R alpha forms, cells expressing IL-15R alpha forms, and therapeutic uses of IL-15R alpha and IL-15/IL-15R alpha complexes
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
US9963513B2
(en)
|
2013-02-05 |
2018-05-08 |
Engmab Sàrl |
Method for the selection of antibodies against BCMA
|
RS57106B1
(sr)
|
2013-02-19 |
2018-06-29 |
Novartis Ag |
Derivati benzotiofena i njihove kompozicije kao selektivni degraderi estrogenskog receptora
|
US9573988B2
(en)
|
2013-02-20 |
2017-02-21 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
|
WO2014130657A1
(en)
|
2013-02-20 |
2014-08-28 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
|
WO2014138805A1
(en)
|
2013-03-14 |
2014-09-18 |
Csl Limited |
Anti il-3r alpha agents and uses thereof
|
WO2014138819A1
(en)
|
2013-03-14 |
2014-09-18 |
Csl Limited |
Agents that neutralize il-3 signaling and uses thereof
|
PL2970464T3
(pl)
|
2013-03-15 |
2020-10-05 |
Glaxosmithkline Intellectual Property Development Limited |
Wiążące białka anty-lag-3
|
AR095374A1
(es)
|
2013-03-15 |
2015-10-14 |
Amgen Res (Munich) Gmbh |
Moléculas de unión para bcma y cd3
|
US9657105B2
(en)
|
2013-03-15 |
2017-05-23 |
City Of Hope |
CD123-specific chimeric antigen receptor redirected T cells and methods of their use
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
CA2908668C
(en)
|
2013-04-03 |
2023-03-14 |
Memorial Sloan-Kettering Cancer Center |
Effective generation of tumor-targeted t cells derived from pluripotent stem cells
|
CA2910278C
(en)
|
2013-05-02 |
2021-09-28 |
Anaptysbio, Inc. |
Antibodies directed against programmed death-1 (pd-1)
|
EP3004169B1
(en)
|
2013-05-31 |
2023-03-22 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind pd-1
|
WO2014209804A1
(en)
|
2013-06-24 |
2014-12-31 |
Biomed Valley Discoveries, Inc. |
Bispecific antibodies
|
TWI725931B
(zh)
|
2013-06-24 |
2021-05-01 |
美商建南德克公司 |
抗fcrh5抗體
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
ES2927567T3
(es)
|
2013-09-13 |
2022-11-08 |
Beigene Switzerland Gmbh |
Anticuerpos anti-PD1 y su uso como productos terapéuticos y de diagnóstico
|
EP3060581A4
(en)
|
2013-10-25 |
2017-06-07 |
Dana-Farber Cancer Institute, Inc. |
Anti-pd-l1 monoclonal antibodies and fragments thereof
|
WO2015081158A1
(en)
|
2013-11-26 |
2015-06-04 |
Bristol-Myers Squibb Company |
Method of treating hiv by disrupting pd-1/pd-l1 signaling
|
JP6502959B2
(ja)
|
2013-12-12 |
2019-04-17 |
上海恒瑞医薬有限公司 |
Pd−1抗体、その抗原結合性断片及びそれらの医学的使用
|
CN116478927A
(zh)
|
2013-12-19 |
2023-07-25 |
诺华股份有限公司 |
人间皮素嵌合抗原受体及其用途
|
HRP20220214T1
(hr)
|
2014-01-15 |
2022-04-29 |
Kadmon Corporation, Llc |
Imunomodulacijska sredstva
|
US20170015758A1
(en)
|
2014-01-21 |
2017-01-19 |
Medimmune, Llc |
Compositions And Methods For Modulating And Redirecting Immune Responses
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
PL3556775T3
(pl)
|
2014-01-28 |
2022-01-31 |
Bristol-Myers Squibb Company |
Przeciwciała anty-lag-3 w leczeniu nowotworów hematologicznych
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
BR112016020953A2
(pt)
|
2014-03-13 |
2018-01-23 |
Hoffmann La Roche |
composto, kit, composição farmacêutica, uso de composto, método de tratamento e invenção
|
TWI697500B
(zh)
|
2014-03-14 |
2020-07-01 |
瑞士商諾華公司 |
針對lag-3之抗體分子及其用途
|
JP2017513818A
(ja)
|
2014-03-15 |
2017-06-01 |
ノバルティス アーゲー |
キメラ抗原受容体を使用する癌の処置
|
EA201692458A1
(ru)
|
2014-05-28 |
2017-06-30 |
Агенус Инк. |
Анти-gitr антитела и способы их применения
|
US9885721B2
(en)
|
2014-05-29 |
2018-02-06 |
Spring Bioscience Corporation |
PD-L1 antibodies and uses thereof
|
KR102204937B1
(ko)
|
2014-06-06 |
2021-01-18 |
브리스톨-마이어스 스큅 컴퍼니 |
글루코코르티코이드-유도 종양 괴사 인자 수용체 (gitr)에 대한 항체 및 그의 용도
|
WO2015195163A1
(en)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
TWI726608B
(zh)
|
2014-07-03 |
2021-05-01 |
英屬開曼群島商百濟神州有限公司 |
抗pd-l1抗體及其作為治療及診斷之用途
|
CN106687483B
(zh)
|
2014-07-21 |
2020-12-04 |
诺华股份有限公司 |
使用人源化抗-bcma嵌合抗原受体治疗癌症
|
MX2017001013A
(es)
|
2014-07-21 |
2018-02-21 |
Novartis Ag |
Tratamiento de cáncer usando un receptor quimérico de antígeno cll-1.
|
BR112017001242A2
(pt)
|
2014-07-21 |
2017-12-05 |
Novartis Ag |
tratamento de câncer usando um receptor antigênico quimérico a cd33
|
ES2878449T3
(es)
|
2014-07-24 |
2021-11-18 |
2Seventy Bio Inc |
Receptores antigénicos quiméricos de BCMA
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
CA2958553A1
(en)
|
2014-08-19 |
2016-02-25 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
EP3201232A1
(en)
|
2014-10-03 |
2017-08-09 |
Dana-Farber Cancer Institute, Inc. |
Glucocorticoid-induced tumor necrosis factor receptor (gitr) antibodies and methods of use thereof
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
US9988452B2
(en)
|
2014-10-14 |
2018-06-05 |
Novartis Ag |
Antibody molecules to PD-L1 and uses thereof
|
AU2015341801B2
(en)
|
2014-11-06 |
2021-05-06 |
F. Hoffmann-La Roche Ag |
Anti-TIM3 antibodies and methods of use
|
WO2016075176A1
(en)
|
2014-11-11 |
2016-05-19 |
Medimmune Limited |
Therapeutic combinations comprising anti-cd73 antibodies and a2a receptor inhibitor and uses thereof
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
WO2016111947A2
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
EP3265486A4
(en)
|
2015-03-06 |
2018-11-14 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind tim3
|
MA41867A
(fr)
|
2015-04-01 |
2018-02-06 |
Anaptysbio Inc |
Anticorps dirigés contre l'immunoglobuline de cellule t et protéine 3 de mucine (tim-3)
|
MX2017015260A
(es)
|
2015-06-03 |
2018-02-19 |
Squibb Bristol Myers Co |
Anticuerpos anti receptor de factor de necrosis tumoral inducible por glucocorticoide (gitr) para diagnostico del cancer.
|
EP3325512B1
(en)
|
2015-07-23 |
2023-09-06 |
Inhibrx, Inc. |
Multivalent and multispecific gitr-binding fusion proteins
|
WO2017025918A1
(en)
|
2015-08-11 |
2017-02-16 |
Novartis Ag |
5-bromo-2,6-di-(lh-pyrazol-l-yl)pyrimidin-4-amine for use in the treatment of cancer
|
EP3334758A1
(en)
|
2015-08-12 |
2018-06-20 |
Medimmune Limited |
Gitrl fusion proteins and uses thereof
|
GEP20207182B
(en)
|
2015-08-13 |
2020-11-25 |
Merck Sharp & Dohme |
Cyclic di-nucleotide compounds as sting agonists
|
EP3526202A4
(en)
|
2016-10-11 |
2020-04-29 |
Arvinas, Inc. |
COMPOUNDS AND METHODS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR
|
WO2018102725A1
(en)
|
2016-12-01 |
2018-06-07 |
Arvinas, Inc. |
Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders
|
JP7266526B6
(ja)
*
|
2017-01-26 |
2024-02-15 |
アルビナス・オペレーションズ・インコーポレイテッド |
エストロゲン受容体タンパク質分解性の調節因子およびその関連方法
|
TWI793151B
(zh)
*
|
2017-08-23 |
2023-02-21 |
瑞士商諾華公司 |
3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
|
JP2021501570A
(ja)
*
|
2017-10-18 |
2021-01-21 |
ノバルティス アーゲー |
選択的タンパク質分解のための組成物及び方法
|