|
US4515810A
(en)
*
|
1983-10-06 |
1985-05-07 |
American Cyanamid Company |
Composition of matter
|
|
US5962490A
(en)
|
1987-09-25 |
1999-10-05 |
Texas Biotechnology Corporation |
Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
|
US5004651A
(en)
*
|
1989-01-24 |
1991-04-02 |
Abbott Laboratories |
Stabilizing system for solid dosage forms
|
|
AU645070B2
(en)
*
|
1990-04-10 |
1994-01-06 |
Nb International Technologies |
Use of short chain fatty acid containing lipids to maintain gastrointestinal integrity and function in patients DO NOT SEAL - SEE LETTER DATED 22.03.94
|
|
US6342610B2
(en)
|
1993-05-20 |
2002-01-29 |
Texas Biotechnology Corp. |
N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
|
HU227183B1
(en)
|
1997-04-28 |
2010-09-28 |
Encysive Pharmaceuticals Inc |
Sulfonamide derivatives and pharmaceutical compositions containing them for the treatment of endothelin-mediated disorders
|
|
US5783705A
(en)
|
1997-04-28 |
1998-07-21 |
Texas Biotechnology Corporation |
Process of preparing alkali metal salys of hydrophobic sulfonamides
|
|
US6362009B1
(en)
|
1997-11-21 |
2002-03-26 |
Merck & Co., Inc. |
Solid phase synthesis of heterocycles
|
|
US7169410B1
(en)
*
|
1998-05-19 |
2007-01-30 |
Sdg, Inc. |
Targeted liposomal drug delivery system
|
|
US6638977B1
(en)
|
1999-11-19 |
2003-10-28 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists
|
|
WO2001036351A2
(en)
|
1999-11-19 |
2001-05-25 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists related applications
|
|
US7897140B2
(en)
|
1999-12-23 |
2011-03-01 |
Health Research, Inc. |
Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
|
|
AUPR868201A0
(en)
*
|
2001-11-05 |
2001-11-29 |
Thorlock International Limited |
Q-factor switching method and apparatus for detecting nuclear quadrupole and nuclear magnetic resonance signals
|
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
|
EP1465869B1
(en)
|
2001-12-21 |
2013-05-15 |
Exelixis Patent Company LLC |
Modulators of lxr
|
|
US6696473B2
(en)
*
|
2001-12-21 |
2004-02-24 |
X-Ceptor Therapeutics, Inc. |
Heterocyclic modulators of nuclear receptors
|
|
US20040001801A1
(en)
*
|
2002-05-23 |
2004-01-01 |
Corvas International, Inc. |
Conjugates activated by cell surface proteases and therapeutic uses thereof
|
|
EP1517684B1
(en)
|
2002-06-27 |
2009-07-22 |
Health Research, Inc. |
Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
|
|
WO2004005289A2
(en)
|
2002-07-02 |
2004-01-15 |
Health Research, Inc. |
Efficient synthesis of pyropheophorbide a and its derivatives
|
|
BRPI0408116B1
(pt)
|
2003-03-05 |
2022-09-20 |
Halozyme, Inc |
Polipeptídeos de hialuronidase solúveis conjugados a polímero, composições farmacêuticas compreendendo polipeptídeos ph20 solúveis, seus usos e processo de preparação, e ácidos nucléicos que codificam polipeptídeos de hialuronidase solúveis
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
US20090123367A1
(en)
*
|
2003-03-05 |
2009-05-14 |
Delfmems |
Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
JP4847868B2
(ja)
*
|
2003-05-14 |
2011-12-28 |
ニューロジェネティック ファーマシューティカルズ、 インコーポレイテッド |
化合物、及び、アミロイドベータの調節におけるその使用
|
|
PL1635824T3
(pl)
*
|
2003-06-03 |
2010-01-29 |
Novartis Ag |
5-Członowe heterocykliczne inhibitory P-38
|
|
US7057100B2
(en)
*
|
2003-06-26 |
2006-06-06 |
The J.C. Robinson Seed Co. |
Inbred corn line W23129
|
|
EP1911754B1
(en)
|
2003-08-13 |
2013-10-09 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
US20050203184A1
(en)
*
|
2003-09-10 |
2005-09-15 |
Petasis Nicos A. |
Benzo lipoxin analogues
|
|
US7420000B2
(en)
|
2003-09-10 |
2008-09-02 |
University Of Southern California |
Amino phosphonate and amino bis-phosphonate derivatives
|
|
CA2583084C
(en)
|
2003-09-19 |
2010-12-07 |
Galileo Pharmaceuticals, Inc. |
7,8-bicycloalkyl-chroman derivatives
|
|
US20050148534A1
(en)
*
|
2003-09-22 |
2005-07-07 |
Castellino Angelo J. |
Small molecule compositions and methods for increasing drug efficiency using compositions thereof
|
|
WO2005090370A1
(en)
*
|
2004-02-05 |
2005-09-29 |
The Regents Of The University Of California |
Pharmacologically active agents containing esterified phosphonates and methods for use thereof
|
|
US8519158B2
(en)
*
|
2004-03-12 |
2013-08-27 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
|
WO2005118511A2
(en)
|
2004-05-20 |
2005-12-15 |
The Scripps Research Institute |
Compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
|
|
US20060135773A1
(en)
*
|
2004-06-17 |
2006-06-22 |
Semple Joseph E |
Trisubstituted nitrogen modulators of tyrosine phosphatases
|
|
EP1786421A2
(en)
*
|
2004-07-09 |
2007-05-23 |
Cengent Therapeutics, Inc. |
Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases
|
|
EA200700225A1
(ru)
|
2004-07-12 |
2008-02-28 |
Айдан Фармасьютикалз, Инк. |
Аналоги тетрапептида
|
|
US20060034978A1
(en)
*
|
2004-08-16 |
2006-02-16 |
Grain Processing Corporation |
Aerosol compositions, devices and methods
|
|
WO2006028970A1
(en)
|
2004-09-02 |
2006-03-16 |
Cengent Therapeutics, Inc. |
Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases
|
|
NZ588432A
(en)
|
2004-09-17 |
2012-03-30 |
Whitehead Biomedical Inst |
Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity
|
|
WO2006066074A2
(en)
|
2004-12-16 |
2006-06-22 |
The Regents Of The University Of California |
Lung-targeted drugs
|
|
WO2006068978A2
(en)
|
2004-12-21 |
2006-06-29 |
Takeda Pharmaceutial Company Limited |
Dipeptidyl peptidase inhibitors
|
|
US8222257B2
(en)
|
2005-04-01 |
2012-07-17 |
The Regents Of The University Of California |
Phosphono-pent-2-en-1-yl nucleosides and analogs
|
|
US20090156545A1
(en)
*
|
2005-04-01 |
2009-06-18 |
Hostetler Karl Y |
Substituted Phosphate Esters of Nucleoside Phosphonates
|
|
KR101275660B1
(ko)
|
2005-05-23 |
2013-06-17 |
내츄럴 얼터너티브즈 인터내셔날, 인크. |
베타-알라닌의 지속적 방출을 위한 조성물 및 방법
|
|
CN101137655A
(zh)
*
|
2005-06-17 |
2008-03-05 |
配体药物公司 |
雄激素受体调节剂化合物和方法
|
|
WO2007002109A2
(en)
*
|
2005-06-20 |
2007-01-04 |
The Regents Of The University Of California |
Multidentate pyrone-derived chelators for medicinal imaging and chelation
|
|
US20080058282A1
(en)
|
2005-08-30 |
2008-03-06 |
Fallon Joan M |
Use of lactulose in the treatment of autism
|
|
US8492428B2
(en)
*
|
2005-09-20 |
2013-07-23 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
|
US8119655B2
(en)
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
WO2007076160A2
(en)
*
|
2005-12-28 |
2007-07-05 |
Acidophil Llc |
C-10 carbamates of taxanes
|
|
DK2383271T3
(da)
|
2006-03-13 |
2013-10-07 |
Kyorin Seiyaku Kk |
Aminoquinoloner som GSK-3-inhibitorer
|
|
CN101404981A
(zh)
*
|
2006-03-13 |
2009-04-08 |
恩希赛弗制药公司 |
治疗舒张性心力衰竭的方法和组合物
|
|
CA2644784A1
(en)
*
|
2006-03-13 |
2007-09-20 |
Jinling Chen |
Formulations of sitaxsentan sodium
|
|
WO2007126841A2
(en)
*
|
2006-03-29 |
2007-11-08 |
Foldrx Pharmaceuticals, Inc. |
Inhibition of alpha-synuclein toxicity
|
|
US20080026061A1
(en)
*
|
2006-06-22 |
2008-01-31 |
Reichwein John F |
Crystalline N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-methyl-4.5-(methylenedioxy)phenylacetyl]-thiophene-3-sulfonamide
|
|
EP2292663B1
(en)
|
2006-08-28 |
2013-10-02 |
Kyowa Hakko Kirin Co., Ltd. |
Antagonistic human light-specific human monoclonal antibodies
|
|
JP5377313B2
(ja)
|
2006-09-21 |
2013-12-25 |
杏林製薬株式会社 |
セリンヒドロラーゼ阻害剤
|
|
JP2010505961A
(ja)
|
2006-10-09 |
2010-02-25 |
タケダ サン ディエゴ インコーポレイテッド |
キナーゼ阻害剤
|
|
EP2079696A2
(en)
|
2006-10-09 |
2009-07-22 |
Takeda San Diego, Inc. |
Kinase inhibitors
|
|
WO2008051502A1
(en)
|
2006-10-19 |
2008-05-02 |
Genzyme Corporation |
Purine derivatives for the treatment of cystic diseases
|
|
DE602007013440D1
(de)
|
2006-10-19 |
2011-05-05 |
Auspex Pharmaceuticals Inc |
Substituierte indole
|
|
WO2008055236A2
(en)
|
2006-10-31 |
2008-05-08 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
|
WO2008057604A2
(en)
*
|
2006-11-08 |
2008-05-15 |
The Regents Of The University Of California |
Small molecule therapeutics, syntheses of analogues and derivatives and methods of use
|
|
JP2010513530A
(ja)
*
|
2006-12-22 |
2010-04-30 |
エンサイシブ・ファーマシューティカルズ・インコーポレイテッド |
C3a受容体の調節剤およびその使用方法
|
|
WO2008106167A1
(en)
*
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the treatment of liver diseases
|
|
EP2144604B1
(en)
|
2007-02-28 |
2011-09-21 |
Conatus Pharmaceuticals, Inc. |
Methods for the treatment of chronic viral hepatitis C using RO 113-0830
|
|
WO2008140859A1
(en)
|
2007-03-15 |
2008-11-20 |
Auspex Pharmaceuticals, Inc. |
Deuterated venlafaxines and 0-desmetylvenlafaxines with serotoninergic and / or norepinephrinergic activity
|
|
CN101801188A
(zh)
*
|
2007-07-12 |
2010-08-11 |
特拉加拉医药品公司 |
治疗癌症、肿瘤和肿瘤相关性疾病的方法和组合物
|
|
WO2009035634A2
(en)
*
|
2007-09-11 |
2009-03-19 |
Activx Biosciences, Inc. |
Cyanoaminoquinolones and tetrazoloaminoquinolones as gsk-3 inhibitors
|
|
EP2203459B1
(en)
|
2007-09-12 |
2016-03-16 |
Kyorin Pharmaceutical Co., Ltd. |
Spirocyclic aminoquinolones as gsk-3 inhibitors
|
|
NZ584760A
(en)
|
2007-09-25 |
2012-03-30 |
Takeda Pharmaceutical |
Polo-like kinase inhibitors
|
|
US20090264421A1
(en)
*
|
2007-10-05 |
2009-10-22 |
Bible Keith C |
Methods and Compositions for Treating Cancer
|
|
AR069244A1
(es)
|
2007-11-08 |
2010-01-06 |
Ambit Biosciences Corp |
Metodos para administrar n-( 5- ter- butil- isoxixasol-3-il) -n'- (4(7-(2- morfolin-4-il- etoxi) imidazo (2,1-b) (1,3) benzotiazol -2-il) fenil) urea para tratar una enfermedad proliferante y composicion farmaceutica
|
|
AU2008327615B2
(en)
*
|
2007-11-21 |
2014-08-21 |
Pharmaxis Ltd. |
Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor
|
|
HRP20130552T1
(en)
|
2007-12-21 |
2013-08-31 |
Ligand Pharmaceuticals, Inc. |
Selective androgen receptor modulators (sarms) and uses thereof
|
|
US8658163B2
(en)
|
2008-03-13 |
2014-02-25 |
Curemark Llc |
Compositions and use thereof for treating symptoms of preeclampsia
|
|
PL2947072T3
(pl)
|
2008-03-17 |
2017-05-31 |
Ambit Biosciences Corporation |
1-(3-(6,7-dimetoksychinazolin-4-yloksy)fenylo)-3-(5-(1,1,1-trifluoro-2-metylopropan-2-ylo)izoksazol-3-ilo)mocznik jako modulator kinazy RAF w leczeniu chorób nowotworowych
|
|
TW200946541A
(en)
*
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
|
US8084025B2
(en)
|
2008-04-18 |
2011-12-27 |
Curemark Llc |
Method for the treatment of the symptoms of drug and alcohol addiction
|
|
CA2724594A1
(en)
*
|
2008-05-20 |
2009-11-26 |
John R. Wetterau |
Niacin and nsaid combination therapy
|
|
WO2010008847A2
(en)
|
2008-06-24 |
2010-01-21 |
Takeda Pharmaceutical Company Limited |
Pi3k/m tor inhibitors
|
|
WO2010002972A1
(en)
|
2008-07-01 |
2010-01-07 |
Curemark, Llc |
Methods and compositions for the treatment of symptoms of neurological and mental health disorders
|
|
KR101694931B1
(ko)
|
2009-01-06 |
2017-01-10 |
큐어론 엘엘씨 |
이. 콜라이에 의한 구강 감염의 치료 또는 예방을 위한 조성물 및 방법
|
|
EP2373791B1
(en)
|
2009-01-06 |
2016-03-30 |
Curelon LLC |
Compositions comprising protease, amylase and lipase for use in the treatment of staphylococcus aureus infections
|
|
WO2010088450A2
(en)
|
2009-01-30 |
2010-08-05 |
Celladon Corporation |
Methods for treating diseases associated with the modulation of serca
|
|
US8568793B2
(en)
|
2009-02-11 |
2013-10-29 |
Hope Medical Enterprises, Inc. |
Sodium nitrite-containing pharmaceutical compositions
|
|
EP2401267B1
(en)
|
2009-02-27 |
2014-01-15 |
Ambit Biosciences Corporation |
Jak kinase modulating quinazoline derivatives and their use in methods
|
|
JP5690286B2
(ja)
|
2009-03-04 |
2015-03-25 |
イデニク プハルマセウティカルス,インコーポレイテッド |
ホスホチオフェン及びホスホチアゾールhcvポリメラーゼ阻害剤
|
|
WO2010105016A1
(en)
|
2009-03-11 |
2010-09-16 |
Ambit Biosciences Corp. |
Combination of an indazolylaminopyrrolotriazine and taxane for cancer treatment
|
|
KR101755725B1
(ko)
|
2009-03-23 |
2017-07-07 |
암비트 바이오사이언시즈 코포레이션 |
병용 요법을 이용한 치료 방법
|
|
EP2411387B1
(en)
|
2009-03-27 |
2015-08-19 |
VetDC, Inc. |
Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
|
WO2010110686A1
(en)
|
2009-03-27 |
2010-09-30 |
Pathway Therapeutics Limited |
Pyrimidinyl and 1,3,5 triazinyl benzimidazoles and their use in cancer therapy
|
|
WO2010111626A2
(en)
|
2009-03-27 |
2010-09-30 |
Takeda Pharmaceutical Company Limited |
Poly (adp-ribose) polymerase (parp) inhibitors
|
|
US9056050B2
(en)
|
2009-04-13 |
2015-06-16 |
Curemark Llc |
Enzyme delivery systems and methods of preparation and use
|
|
JP5847702B2
(ja)
|
2009-04-22 |
2016-01-27 |
アクシキン ファーマシューティカルズ インコーポレーテッド |
2,5−二置換アリールスルホンアミドccr3アンタゴニスト
|
|
NZ595797A
(en)
|
2009-04-22 |
2014-03-28 |
Axikin Pharmaceuticals Inc |
2,5-disubstituted arylsulfonamide ccr3 antagonists
|
|
AU2010239341B2
(en)
|
2009-04-22 |
2015-07-02 |
Axikin Pharmaceuticals, Inc. |
Arylsulfonamide CCR3 antagonists
|
|
SMT202000092T1
(it)
|
2009-05-14 |
2020-05-08 |
Ambit Biosciences Corp |
Formulazione essiccata a spruzzo o liofilizzata di ac220
|
|
EP2532659A1
(en)
|
2009-07-07 |
2012-12-12 |
Pathway Therapeutics, Inc. |
Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy
|
|
AU2010270605B2
(en)
|
2009-07-08 |
2014-07-31 |
Hope Medical Enterprises, Inc. Dba Hope Pharmaceuticals |
Sodium thiosulfate-containing pharmaceutical compositions
|
|
US8404728B2
(en)
|
2009-07-30 |
2013-03-26 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
|
EP2459561A1
(en)
|
2009-07-30 |
2012-06-06 |
Takeda Pharmaceutical Company Limited |
Poly (adp-ribose) polymerase (parp) inhibitors
|
|
US9284307B2
(en)
|
2009-08-05 |
2016-03-15 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors
|
|
JP2013501812A
(ja)
*
|
2009-08-14 |
2013-01-17 |
セレニス セラピューティクス ホールディング エス.エー. |
炎症またはエネルギー代謝/産生関連疾患の治療または予防のためのPPARδリガンドの使用
|
|
WO2011041293A1
(en)
|
2009-09-30 |
2011-04-07 |
Takeda Pharmaceutical Company Limited |
Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
|
|
TW201120037A
(en)
|
2009-10-26 |
2011-06-16 |
Sunesis Pharmaceuticals Inc |
Compounds and methods for treatment of cancer
|
|
US8940790B2
(en)
*
|
2009-11-03 |
2015-01-27 |
Bernard Charles Sherman |
Stable pharmaceutical formulations comprising lubiprostone
|
|
WO2011056764A1
(en)
|
2009-11-05 |
2011-05-12 |
Ambit Biosciences Corp. |
Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
|
|
US8871460B2
(en)
|
2009-11-09 |
2014-10-28 |
Neurogenetic Pharmaceuticals, Inc. |
Gamma-secretase modulatory compounds, methods for identifying same, and uses therefor
|
|
US20110301235A1
(en)
|
2009-12-02 |
2011-12-08 |
Alquest Therapeutics, Inc. |
Organoselenium compounds and uses thereof
|
|
AR079528A1
(es)
|
2009-12-18 |
2012-02-01 |
Idenix Pharmaceuticals Inc |
Inhibidores de arileno o heteroarileno 5,5-fusionado del virus de la hepatitis c
|
|
SG181896A1
(en)
*
|
2009-12-23 |
2012-07-30 |
Map Pharmaceuticals Inc |
Novel ergoline analogs
|
|
CA2784799C
(en)
|
2009-12-30 |
2014-06-10 |
Shanghai Fochon Pharmaceutical Co Ltd |
Certain dipeptidyl peptidase inhibtors
|
|
US8802695B2
(en)
|
2010-02-03 |
2014-08-12 |
Takeda Pharmaceutical Company Limited |
Apoptosis signal-regulating kinase 1 inhibitors
|
|
ES2542404T3
(es)
|
2010-03-02 |
2015-08-05 |
Axikin Pharmaceuticals, Inc. |
Antagonistas de CCR3 de tipo arilsulfonamida enriquecidos isotópicamente
|
|
WO2011112689A2
(en)
|
2010-03-11 |
2011-09-15 |
Ambit Biosciences Corp. |
Saltz of an indazolylpyrrolotriazine
|
|
AR080770A1
(es)
|
2010-03-17 |
2012-05-09 |
Axikin Pharmaceuticals Inc |
Piperidinsulfonamidas moduladoras de la actividad de receptores xcc3, composiciones farmaceuticas que las contienen y uso de las mismas en el tratamiento de patologias respiratorias,tales como asma, entre otras.
|
|
WO2011127019A2
(en)
|
2010-04-07 |
2011-10-13 |
Celgene Corporation |
Methods for treating respiratory viral infection
|
|
CN103153309A
(zh)
|
2010-06-01 |
2013-06-12 |
拜欧赛里克斯公司 |
使用6-环己基-1-羟基-4-甲基-2(1h)-吡啶酮治疗血液恶性肿瘤的方法
|
|
EP2576513A1
(en)
|
2010-06-01 |
2013-04-10 |
Biotheryx Inc. |
Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating proliferative diseases
|
|
CN103108868B
(zh)
|
2010-06-07 |
2015-11-25 |
诺沃梅迪科斯有限公司 |
呋喃基化合物及其用途
|
|
WO2011163636A2
(en)
|
2010-06-24 |
2011-12-29 |
The Regents Of The University Of California |
Compounds and uses thereof in modulating levels of various amyloid beta peptide alloforms
|
|
WO2012012370A1
(en)
|
2010-07-19 |
2012-01-26 |
Summa Health System |
Vitamin c and chromium-free vitamin k, and compositions thereof for treating an nfkb-mediated condition or disease
|
|
EP2611809A1
(en)
|
2010-09-01 |
2013-07-10 |
Ambit Biosciences Corporation |
Azolopyridine and azolopyrimidine compounds and methods of use thereof
|
|
AU2011296046B2
(en)
|
2010-09-01 |
2015-05-14 |
Ambit Biosciences Corporation |
Hydrobromide salts of a pyrazolylaminoquinazoline
|
|
WO2012030914A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Boisciences Corporation |
4-azolylaminoquinazoline derivatives and methods of use thereof
|
|
EP2611793A1
(en)
|
2010-09-01 |
2013-07-10 |
Ambit Biosciences Corporation |
2-cycloquinazoline derivatives and methods of use thereof
|
|
WO2012030944A2
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
Quinoline and isoquinoline compounds and methods of use thereof
|
|
US20120053176A1
(en)
|
2010-09-01 |
2012-03-01 |
Ambit Biosciences Corp. |
Adenosine a3 receptor modulating compounds and methods of use thereof
|
|
CN103298805A
(zh)
|
2010-09-01 |
2013-09-11 |
埃姆比特生物科学公司 |
喹唑啉化合物及其使用方法
|
|
EP2611448A1
(en)
|
2010-09-01 |
2013-07-10 |
Ambit Biosciences Corporation |
7-cyclylquinazoline derivatives and methods of use thereof
|
|
WO2012030917A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
An optically active pyrazolylaminoquinazoline, and pharmaceutical compositions and methods of use thereof
|
|
WO2012030894A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
Thienopyridine and thienopyrimidine compounds and methods of use thereof
|
|
US8859502B2
(en)
|
2010-09-13 |
2014-10-14 |
Celgene Corporation |
Therapy for MLL-rearranged leukemia
|
|
WO2012044641A1
(en)
|
2010-09-29 |
2012-04-05 |
Pathway Therapeutics Inc. |
1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
|
CA2814011A1
(en)
|
2010-10-11 |
2012-04-19 |
Axikin Pharmaceuticals, Inc. |
Salts of arylsulfonamide ccr3 antagonists
|
|
WO2012080050A1
(en)
|
2010-12-14 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Solid forms of a phenoxybenzenesulfonyl compound
|
|
US9353100B2
(en)
|
2011-02-10 |
2016-05-31 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
|
|
WO2012135166A1
(en)
|
2011-03-28 |
2012-10-04 |
Pathway Therapeutics Inc. |
(fused ring arylamino and heterocyclylamino) pyrimidynyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
|
|
EP2691384B1
(en)
|
2011-03-28 |
2016-10-26 |
MEI Pharma, Inc. |
(alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions containing them, and these compounds for use in treating proliferative diseases
|
|
CA2831590A1
(en)
|
2011-03-28 |
2012-10-04 |
Mei Pharma, Inc. |
(alpha-substituted cycloalkylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
DK3305317T3
(da)
|
2011-04-21 |
2020-07-20 |
Curemark Llc |
Forbindelser til behandling af neuropsykiatriske forstyrrelser
|
|
CA2838991A1
(en)
|
2011-06-23 |
2012-12-27 |
Map Pharmaceuticals, Inc. |
Novel fluoroergoline analogs
|
|
WO2013022872A1
(en)
|
2011-08-10 |
2013-02-14 |
Celgene Corporation |
Gene methylation biomarkers and methods of use thereof
|
|
US10226472B2
(en)
|
2011-09-02 |
2019-03-12 |
Syndax Pharmaceuticals, Inc. |
Methods for the treatment of breast cancer
|
|
WO2013037482A1
(en)
|
2011-09-15 |
2013-03-21 |
Phenex Pharmaceuticals Ag |
Farnesoid x receptor agonists for cancer treatment and prevention
|
|
CN104114182A
(zh)
|
2011-09-23 |
2014-10-22 |
细胞基因公司 |
罗米地辛和5-阿扎胞苷在治疗淋巴瘤中的应用
|
|
CA2849903A1
(en)
|
2011-09-26 |
2013-04-04 |
Celgene Corporation |
Combination therapy for chemoresistant cancers
|
|
JP6162709B2
(ja)
|
2011-11-01 |
2017-07-12 |
セルジーン コーポレイション |
シチジンアナログの経口製剤を使用して癌を治療する方法
|
|
WO2013085902A1
(en)
|
2011-12-05 |
2013-06-13 |
The University Of Texas M.D. |
Combination therapy methods for treating an inflammatory breast cancer
|
|
EP2793580A4
(en)
|
2011-12-19 |
2015-05-20 |
Map Pharmaceuticals Inc |
NEW DERIVATIVES OF ISO-ERGOLINE
|
|
SG10201506202RA
(en)
|
2011-12-21 |
2015-09-29 |
Map Pharmaceuticals Inc |
Novel neuromodulatory compounds
|
|
US9611253B2
(en)
|
2012-02-29 |
2017-04-04 |
Ambit Biosciences Corporation |
Solid forms comprising optically active pyrazolylaminoquinazoline, compositions thereof, and uses therewith
|
|
PT2822936T
(pt)
|
2012-03-07 |
2021-12-02 |
Univ Of Delhi |
Derivados da aminoquinolina e suas utilizações
|
|
EP2852586A1
(en)
|
2012-03-16 |
2015-04-01 |
Axikin Pharmaceuticals, Inc. |
3,5-diaminopyrazole kinase inhibitors
|
|
WO2013148919A1
(en)
|
2012-03-30 |
2013-10-03 |
The Regents Of The University Of Colorado, A Body Corporate |
Treatment of multiple myeloma
|
|
HRP20180953T1
(hr)
|
2012-05-02 |
2018-07-27 |
Boehringer Ingelheim International Gmbh |
Supstituirani 3-haloalilaminski inhibitori za ssao i njihove uporabe
|
|
US10350278B2
(en)
|
2012-05-30 |
2019-07-16 |
Curemark, Llc |
Methods of treating Celiac disease
|
|
EP2861562B1
(en)
|
2012-06-14 |
2018-05-09 |
Mayo Foundation For Medical Education And Research |
Pyrazole derivatives as inhibitors of stat3
|
|
US9012640B2
(en)
|
2012-06-22 |
2015-04-21 |
Map Pharmaceuticals, Inc. |
Cabergoline derivatives
|
|
US8551535B1
(en)
|
2012-08-06 |
2013-10-08 |
Sarah McCann |
Homeopathic remedies and methods for enhancing weight loss
|
|
US9074186B2
(en)
|
2012-08-15 |
2015-07-07 |
Boston Medical Center Corporation |
Production of red blood cells and platelets from stem cells
|
|
BR112015004959A2
(pt)
|
2012-09-07 |
2017-07-04 |
Axikin Pharmaceuticals Inc |
composto isotopicamente enriquecido, composição farmacêutica, método para tratar, prevenir ou amenizar um ou mais sintomas de uma doença, distúrbio ou condição mediada por ccr3, relacionada a eosinófilos, relacionada a basófilos, relacionada a mastócitos ou relacionada a mastócitos em um sujeito, método para tratar, prevenir ou amenizar um ou mais sintomas de uma doença inflamatória em um sujeito e método para modular a atividade de ccr3.
|
|
AU2013202506B2
(en)
|
2012-09-07 |
2015-06-18 |
Celgene Corporation |
Resistance biomarkers for hdac inhibitors
|
|
WO2014055647A1
(en)
|
2012-10-03 |
2014-04-10 |
Mei Pharma, Inc. |
(sulfinyl and sulfonyl benzimidazolyl) pyrimidines and triazines, pharmaceutical compositions thereof, and their use for treating proliferative diseases
|
|
CA2890177A1
(en)
|
2012-11-08 |
2014-05-15 |
Summa Health System |
Vitamin c, vitamin k, a polyphenol, and combinations thereof for wound healing
|
|
AU2013202507B9
(en)
|
2012-11-14 |
2015-08-13 |
Celgene Corporation |
Inhibition of drug resistant cancer cells
|
|
EP2925718B1
(en)
|
2012-11-30 |
2018-08-01 |
Novomedix, LLC |
Substituted biaryl sulfonamides and the use thereof
|
|
CA2895829A1
(en)
|
2012-12-21 |
2014-06-26 |
Map Pharmaceuticals, Inc. |
Novel methysergide derivatives
|
|
US9169214B2
(en)
|
2012-12-21 |
2015-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
|
|
WO2014110305A1
(en)
|
2013-01-11 |
2014-07-17 |
Mayo Foundation For Medical Education And Research |
Vitamins c and k for treating polycystic diseases
|
|
EP2958561B1
(en)
|
2013-02-22 |
2019-12-11 |
University Of Southern California |
Lipoxin analogs for use in the treatment of ophthalmic diseases and disorders
|
|
EP2968296B1
(en)
|
2013-03-12 |
2020-09-02 |
The Regents of the University of California |
Gamma-secretase modulators
|
|
ES2834430T3
(es)
|
2013-03-15 |
2021-06-17 |
Univ Southern California |
Procedimientos, compuestos y composiciones para el tratamiento de enfermedades relacionadas con la angiotensina
|
|
SG10201800188SA
(en)
|
2013-03-15 |
2018-02-27 |
Univ California |
Acyclic nucleoside phosphonate diesters
|
|
WO2014160698A1
(en)
|
2013-03-26 |
2014-10-02 |
Celgene Corporation |
SOLID FORMS COMPRISING 4-AMINO-I-β-D-RIBOFURANOSYL-1,3,5-TRIAZIN-2(1H)-ONE AND A COFORMER, COMPOSITIONS AND METHODS OF USE THEREOF
|
|
ES2891755T3
(es)
|
2013-06-06 |
2022-01-31 |
Pf Medicament |
Anticuerpos anti-C10orf54 y utilizaciones de los mismos
|
|
EP2815749A1
(en)
|
2013-06-20 |
2014-12-24 |
IP Gesellschaft für Management mbH |
Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
|
|
NZ631142A
(en)
|
2013-09-18 |
2016-03-31 |
Axikin Pharmaceuticals Inc |
Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
|
|
WO2015042375A1
(en)
|
2013-09-20 |
2015-03-26 |
Idenix Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015051336A1
(en)
|
2013-10-03 |
2015-04-09 |
David Wise |
Compositions and methods for treating pelvic pain and other conditions
|
|
EP3083589B1
(en)
|
2013-12-20 |
2019-12-18 |
Sunshine Lake Pharma Co., Ltd. |
Substituted piperazine compounds and methods of use thereof
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
MX377384B
(es)
|
2014-03-20 |
2025-03-10 |
Capella Therapeutics Inc |
Derivados de bencimidazol como inhibidores de tirosina cinasa erbb para el tratamiento del cáncer.
|
|
KR102409739B1
(ko)
|
2014-03-20 |
2022-06-17 |
카펠라 테라퓨틱스, 인크. |
암 치료용의 erbb 티로신 키나제 억제제로서의 벤즈이미다졸 유도체
|
|
US9399637B2
(en)
|
2014-03-28 |
2016-07-26 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
|
EP3444011A1
(en)
|
2014-05-12 |
2019-02-20 |
Conatus Pharmaceuticals, Inc. |
Treatment of the complications of chronic liver disease with emricasan
|
|
WO2015195786A2
(en)
|
2014-06-17 |
2015-12-23 |
Celgene Corporation |
Methods for treating cancers using oral formulations of cytidine analogs
|
|
WO2015195634A1
(en)
|
2014-06-17 |
2015-12-23 |
Celgne Corporation |
Methods for treating epstein-barr virus (ebv) associated cancers using oral formulations of 5-azacytidine
|
|
WO2015195474A1
(en)
|
2014-06-18 |
2015-12-23 |
Biotheryx, Inc. |
Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating inflammatory, neurodegenerative, or immune-mediated diseases
|
|
US9499514B2
(en)
|
2014-07-11 |
2016-11-22 |
Celgene Corporation |
Antiproliferative compounds and methods of use thereof
|
|
WO2016025129A1
(en)
|
2014-08-14 |
2016-02-18 |
Alhamadsheh Mamoun M |
Conjugation of pharmaceutically active agents with transthyretin ligands through adjustable linkers to increase serum half-life
|
|
CN112898345A
(zh)
|
2014-09-15 |
2021-06-04 |
加利福尼亚大学董事会 |
核苷酸类似物
|
|
US20170354639A1
(en)
|
2014-10-24 |
2017-12-14 |
Biogen Ma Inc. |
Diterpenoid derivatives and methods of use thereof
|
|
US10472346B2
(en)
|
2014-10-31 |
2019-11-12 |
The General Hospital Corporation |
Potent gamma-secretase modulators
|
|
BR112017012344B1
(pt)
|
2014-12-11 |
2024-02-06 |
Pierre Fabre Medicament |
Anticorpo anti-c10orf54 ou fragmento de ligação ao antígeno do mesmo, conjugado anticorpo-fármaco, composição farmacêutica, kit, seus usos, polinucleotídeo, vetor de expressão e métodos de produção do anticorpo ou fragmento de ligação ao antígeno e de detecção c10orf54 em uma amostra
|
|
MY191736A
(en)
|
2014-12-23 |
2022-07-13 |
Axikin Pharmaceuticals Inc |
3,5-diaminopyrazole kinase inhibitors
|
|
CN113149982A
(zh)
|
2015-01-20 |
2021-07-23 |
Xoc制药股份有限公司 |
麦角灵化合物及其用途
|
|
EP3247357A4
(en)
|
2015-01-20 |
2018-07-11 |
Xoc Pharmaceuticals, Inc |
Isoergoline compounds and uses thereof
|
|
HUE061070T2
(hu)
|
2015-03-03 |
2023-05-28 |
Kymab Ltd |
Ellenanyagok, alkalmazások és eljárások
|
|
ES2986548T3
(es)
|
2015-03-20 |
2024-11-11 |
Syndax Pharmaceuticals Inc |
Combinación de inhibidor de HDAC y anticuerpo anti-PD-1 para el tratamiento del cáncer, en donde la combinación no comprende 5-azacitidina
|
|
US20180156807A1
(en)
|
2015-04-29 |
2018-06-07 |
New York University |
Method for treating high-grade gliomas
|
|
WO2016210180A2
(en)
|
2015-06-23 |
2016-12-29 |
Neurocrine Biosciences, Inc. |
Vmat2 inhibitors for treating neurological diseases or disorders
|
|
SMT201900452T1
(it)
|
2015-08-17 |
2019-11-13 |
Kura Oncology Inc |
Metodi di trattamento di pazienti di cancro con inibitori di farnesil trasferasi
|
|
MX2018002640A
(es)
|
2015-09-02 |
2018-06-20 |
Syndax Pharmaceuticals Inc |
Seleccion de pacientes para la terapia de combinacion.
|
|
EP3347097B1
(en)
|
2015-09-11 |
2021-02-24 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora
|
|
US10377782B2
(en)
|
2015-09-15 |
2019-08-13 |
The Regents Of The University Of California |
Nucleotide analogs
|
|
WO2017050803A1
(en)
|
2015-09-25 |
2017-03-30 |
Universität Duisburg-Essen |
Agents inhibiting kallikrein-8 for use in the prevention or treatment of alzheimer's disease
|
|
TN2018000121A1
(en)
|
2015-10-30 |
2019-10-04 |
Neurocrine Biosciences Inc |
Valbenazine salts and polymorphs thereof
|
|
WO2017079566A1
(en)
|
2015-11-05 |
2017-05-11 |
Conatus Pharmaceuticals, Inc. |
Caspase inhibitors for use in the treatment of liver cancer
|
|
US10112924B2
(en)
|
2015-12-02 |
2018-10-30 |
Astraea Therapeutics, Inc. |
Piperdinyl nociceptin receptor compounds
|
|
CN108883103A
(zh)
|
2015-12-02 |
2018-11-23 |
阿斯特来亚治疗有限责任公司 |
哌啶基痛敏肽受体化合物
|
|
LT3394057T
(lt)
|
2015-12-23 |
2022-06-27 |
Neurocrine Biosciences, Inc. |
Sintezės būdas, skirtas pagaminti (s)-(2r,3r,11br)-3-izobutil-9,10-dimetoksi-2,3,4,6,7,11b-heksahidro-1h-pirido[2,1-a]izochinolin-2-ilo 2-amino-3-metilbutanoato di(4-metilbenzensulfonatą)
|
|
US20190022043A1
(en)
|
2015-12-31 |
2019-01-24 |
Conatus Pharmaceuticals Inc. |
Methods of using caspase inhibitors in treatment of liver disease
|
|
BR112018013761A2
(pt)
|
2016-01-08 |
2018-12-11 |
Celgene Corp |
compostos antiproliferativos e suas composições farmacêuticas e usos
|
|
US10960013B2
(en)
|
2016-03-04 |
2021-03-30 |
East Carolina University |
J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders
|
|
WO2017156191A1
(en)
|
2016-03-08 |
2017-09-14 |
Los Gatos Pharmaceuticals, Inc. |
Composite nanoparticles and uses thereof
|
|
EP3426352A4
(en)
|
2016-03-08 |
2019-11-13 |
Los Gatos Pharmaceuticals, Inc. |
CAMPTOTHECIN DERIVATIVES AND USES THEREOF
|
|
EP3442940A1
(en)
|
2016-04-11 |
2019-02-20 |
Clexio Biosciences Ltd. |
Deuterated ketamine derivatives
|
|
US10047077B2
(en)
|
2016-04-13 |
2018-08-14 |
Skyline Antiinfectives, Inc. |
Deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams
|
|
WO2017184968A1
(en)
|
2016-04-22 |
2017-10-26 |
Kura Oncology, Inc. |
Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors
|
|
DK3454904T3
(da)
|
2016-05-13 |
2023-02-06 |
Pasteur Institut |
Inhibering af beta-2-nikotiniske acetylcholinreceptorer til at behandle patologi ved Alzheimers sygdom
|
|
TWI753910B
(zh)
|
2016-05-16 |
2022-02-01 |
美商拜歐斯瑞克斯公司 |
吡啶硫酮、其醫藥組合物及其治療增生性、炎性、神經退化性或免疫介導疾病之治療用途
|
|
WO2018013689A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, method of preparation and use thereof
|
|
WO2018013693A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and cocrystals comprising 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione compositions and methods of use thereof
|
|
US10919904B2
(en)
|
2016-08-17 |
2021-02-16 |
North Carolina State University |
Northern-southern route to synthesis of bacteriochlorins
|
|
US20190201409A1
(en)
|
2016-09-19 |
2019-07-04 |
Mei Pharma, Inc. |
Combination therapy
|
|
HUE053927T2
(hu)
|
2016-11-03 |
2021-07-28 |
Kura Oncology Inc |
Farneziltranszferáz inhibitorok rák kezelésében történõ alkalmazásra
|
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
US10106521B2
(en)
|
2016-11-09 |
2018-10-23 |
Phloronol, Inc. |
Eckol derivatives, methods of synthesis and uses thereof
|
|
US10988442B2
(en)
|
2016-11-09 |
2021-04-27 |
Novomedix, Llc |
Nitrite salts of 1,1-dimethylbiguanide, pharmaceutical compositions, and methods of use
|
|
US10836774B2
(en)
|
2016-11-30 |
2020-11-17 |
North Carolina State University |
Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds
|
|
US10799503B2
(en)
|
2016-12-01 |
2020-10-13 |
Ignyta, Inc. |
Methods for the treatment of cancer
|
|
TW202515564A
(zh)
|
2016-12-02 |
2025-04-16 |
美商紐羅克里生物科學有限公司 |
戊苯那嗪(valbenazine)於治療精神分裂症或情感性精神分裂症之用途
|
|
WO2018140092A1
(en)
|
2017-01-27 |
2018-08-02 |
Obrien Christopher F |
Methods for the administration of certain vmat2 inhibitors
|
|
CN110381960A
(zh)
|
2017-02-02 |
2019-10-25 |
麦克马斯特大学 |
作为抗微生物剂的增强剂的碳酸氢盐
|
|
MX2021015220A
(es)
|
2017-02-17 |
2022-12-01 |
Eidos Therapeutics Inc |
Procesos para preparar ácido 3-(3-(3,5-dimetil-1h-pirazol-4-il)pro poxi)-4- 5-fluorobenzoico (ag-10), sus compuestos intermedios, y sales del mismo.
|
|
US10137121B2
(en)
|
2017-02-21 |
2018-11-27 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
CN114796218A
(zh)
|
2017-02-21 |
2022-07-29 |
库拉肿瘤学公司 |
使用法尼基转移酶抑制剂治疗癌症的方法
|
|
WO2018164996A1
(en)
|
2017-03-06 |
2018-09-13 |
Neurocrine Biosciences, Inc. |
Dosing regimen for valbenazine
|
|
CN110709386B
(zh)
|
2017-03-30 |
2022-06-07 |
凯瑞康宁生物工程(武汉)有限公司 |
双环杂芳基衍生物及其制备与用途
|
|
EP3609528A4
(en)
|
2017-04-10 |
2020-12-23 |
Curemark, LLC |
COMPOSITIONS FOR THE TREATMENT OF ADDICTION
|
|
WO2018195727A1
(en)
|
2017-04-24 |
2018-11-01 |
Tsinghua University |
Use of autoinducer-related pathway in inducing apoptosis and anti-infective therapy
|
|
WO2018200605A1
(en)
|
2017-04-26 |
2018-11-01 |
Neurocrine Biosciences, Inc. |
Use of valbenazine for treating levodopa-induced dyskinesia
|
|
JOP20190219A1
(ar)
|
2017-05-09 |
2019-09-22 |
Cardix Therapeutics LLC |
تركيبات صيدلانية وطرق لعلاج أمراض القلب والأوعية الدموية
|
|
US10085999B1
(en)
|
2017-05-10 |
2018-10-02 |
Arixa Pharmaceuticals, Inc. |
Beta-lactamase inhibitors and uses thereof
|
|
BR112019025420A2
(pt)
|
2017-06-01 |
2020-06-16 |
Xoc Pharmaceuticals, Inc. |
Compostos policíclicos e usos destes
|
|
JP2020525459A
(ja)
|
2017-06-26 |
2020-08-27 |
アンスティテュ・パストゥール |
Hivリザーバーを排除し、ウイルス負荷を低減する処置
|
|
US10806730B2
(en)
|
2017-08-07 |
2020-10-20 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
AU2018313738B2
(en)
|
2017-08-07 |
2024-07-04 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
JP7069295B2
(ja)
|
2017-08-17 |
2022-05-17 |
エックスダブリューファルマ リミテッド |
活性酸素種スカベンジャー誘導体の調製および使用
|
|
US11571401B2
(en)
|
2017-09-01 |
2023-02-07 |
East Carolina University |
Compounds, compositions, kits, and methods for activating immune cells and/or an immune system response
|
|
EP3988561B1
(en)
|
2017-09-04 |
2023-06-07 |
XWPharma Ltd. |
Preparation and use of reactive oxygen species scavenger
|
|
US20200276184A1
(en)
|
2017-09-21 |
2020-09-03 |
Neurocrine Biosciences, Inc. |
High Dosage Valbenazine Formulation and Compositions, Methods, and Kits Related Thereto
|
|
MX2020004133A
(es)
|
2017-10-04 |
2020-08-13 |
Univ California |
Oligosacaridos inmunomoduladores.
|
|
EA202090932A1
(ru)
|
2017-10-10 |
2021-05-20 |
Нейрокрин Байосайенсиз, Инк |
Способы введения некоторых vmat2-ингибиторов
|
|
KR20250070134A
(ko)
|
2017-10-10 |
2025-05-20 |
뉴로크린 바이오사이언시즈 인코퍼레이티드 |
특정 vmat2 억제제의 투여 방법
|
|
US20190216751A1
(en)
|
2017-11-15 |
2019-07-18 |
California State University Northridge |
Compositions and Methods for the Treatment and Prevention of Cancer
|
|
EP3710006A4
(en)
|
2017-11-19 |
2021-09-01 |
Sunshine Lake Pharma Co., Ltd. |
SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR METHODS OF USE
|
|
WO2019113269A1
(en)
|
2017-12-08 |
2019-06-13 |
Kura Oncology, Inc. |
Methods of treating cancer patients with farnesyltransferase inhibitors
|
|
US11701334B2
(en)
|
2018-01-10 |
2023-07-18 |
Cura Therapeutics, Llc |
Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications
|
|
TW201929847A
(zh)
|
2018-01-10 |
2019-08-01 |
美商克拉治療有限責任公司 |
包含二羧酸之醫藥組合物及其治療應用
|
|
SG11202006575TA
(en)
|
2018-01-10 |
2020-08-28 |
Xw Lab Inc |
Prodrugs of ketamine, compositions and uses thereof
|
|
CN111971280A
(zh)
|
2018-02-08 |
2020-11-20 |
耶路撒冷希伯来大学伊萨姆研究发展公司 |
杂芳基化合物、其药物组合物和其治疗用途
|
|
CA3094711A1
(en)
|
2018-03-23 |
2019-09-26 |
Eidos Therapeutics, Inc. |
Methods of treating ttr amyloidosis using ag10
|
|
BR112020024062A2
(pt)
|
2018-04-27 |
2021-02-09 |
Spruce Biosciences, Inc. |
métodos para o tratamento de tumores de restos adrenais de testículo e de ovário
|
|
WO2019217484A1
(en)
|
2018-05-07 |
2019-11-14 |
Syndax Pharmaceuticals, Inc. |
Selection of patients for combination therapy
|
|
WO2019232724A1
(en)
|
2018-06-06 |
2019-12-12 |
Xw Laboratories, Inc. |
Compounds as nuclear transport modulators and uses thereof
|
|
AU2019287524A1
(en)
|
2018-06-14 |
2020-12-24 |
Neurocrine Biosciences, Inc. |
VMAT2 inhibitor compounds, compositions, and methods relating thereto
|
|
WO2020006341A1
(en)
|
2018-06-29 |
2020-01-02 |
Conatus Pharmaceuticals, Inc. |
(s)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating cardiovascular diseases
|
|
CA3106418A1
(en)
|
2018-07-20 |
2020-01-23 |
Pierre Fabre Medicament |
Receptor for vista
|
|
WO2020019247A1
(en)
|
2018-07-26 |
2020-01-30 |
Xw Laboratories, Inc. |
Compounds as neurokinin-1 receptor antagonists and uses thereof
|
|
WO2020024060A1
(en)
|
2018-08-01 |
2020-02-06 |
Mcmaster University |
Methods for inhibiting microbe growth
|
|
JP2021528481A
(ja)
|
2018-08-15 |
2021-10-21 |
ニューロクライン バイオサイエンシーズ,インコーポレイテッド |
特定のvmat2阻害剤を投与するための方法
|
|
WO2020037189A1
(en)
|
2018-08-17 |
2020-02-20 |
Eidos Therapeutics, Inc. |
Formulations of ag10
|
|
CN114042070A
(zh)
|
2018-09-30 |
2022-02-15 |
凯瑞康宁生物工程(武汉)有限公司 |
作为神经元组胺受体-3拮抗剂的化合物及其用途
|
|
JP2022506463A
(ja)
|
2018-11-01 |
2022-01-17 |
クラ オンコロジー, インコーポレイテッド |
ファルネシルトランスフェラーゼ阻害剤でがんを治療する方法
|
|
EP3898609A1
(en)
|
2018-12-19 |
2021-10-27 |
Shy Therapeutics LLC |
Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
|
|
WO2020128033A1
(en)
|
2018-12-20 |
2020-06-25 |
Institut Pasteur |
Cellular metabolism of hiv-1 reservoir seeding in cd4+ t cells
|
|
AU2019403379A1
(en)
|
2018-12-21 |
2021-07-15 |
Kura Oncology, Inc. |
Therapies for squamous cell carcinomas
|
|
TWI839461B
(zh)
|
2019-02-06 |
2024-04-21 |
美商戴斯阿爾法股份有限公司 |
Il-17a調節物及其用途
|
|
US20220142983A1
(en)
|
2019-03-01 |
2022-05-12 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
ES2988904T3
(es)
|
2019-03-07 |
2024-11-22 |
Nobo Medicine Inc |
Inhibidores de caspasa y métodos de utilización de los mismos
|
|
US20220143006A1
(en)
|
2019-03-15 |
2022-05-12 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
SG11202110472WA
(en)
|
2019-03-29 |
2021-10-28 |
Kura Oncology Inc |
Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors
|
|
WO2020205387A1
(en)
|
2019-04-01 |
2020-10-08 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
AU2020257397A1
(en)
|
2019-04-19 |
2021-12-16 |
Ligand Pharmaceuticals Inc. |
Crystalline forms and methods of producing crystalline forms of a compound
|
|
US20220305001A1
(en)
|
2019-05-02 |
2022-09-29 |
Kura Oncology, Inc. |
Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors
|
|
EP4636054A3
(en)
|
2019-05-20 |
2025-12-31 |
NIRvana Sciences Inc. |
Narrow-emitting dyes, compositions comprising them, and processes for their manufacture and use
|
|
CN114222803B
(zh)
|
2019-05-20 |
2025-01-07 |
尼尔瓦纳科学股份有限公司 |
窄发射染料、包含其的组合物以及制备和使用其的方法
|
|
CN114423752B
(zh)
|
2019-06-03 |
2025-06-24 |
耶路撒冷希伯来大学伊萨姆研究发展公司 |
吡唑化合物的非吸湿性结晶盐和其药物组合物与用途
|
|
CA3146157A1
(en)
|
2019-07-11 |
2021-01-14 |
Cura Therapeutics, Llc |
Sulfone compounds and pharmaceutical compositions thereof, and their therapeutic applications for the treatment of neurodegenerative diseases
|
|
AU2020310190A1
(en)
|
2019-07-11 |
2022-02-24 |
Cura Therapeutics, Llc |
Phenyl compounds and pharmaceutical compositions thereof, and their therapeutic applications
|
|
EP4464688A1
(en)
|
2019-07-26 |
2024-11-20 |
Espervita Therapeutics, Inc. |
Functionalized long-chain hydrocarbon mono- and di-carboxylic acids useful for the prevention or treatment of disease
|
|
US10940141B1
(en)
|
2019-08-23 |
2021-03-09 |
Neurocrine Biosciences, Inc. |
Methods for the administration of certain VMAT2 inhibitors
|
|
CA3154608A1
(en)
|
2019-09-16 |
2021-03-25 |
Dice Alpha, Inc. |
Il-17a modulators and uses thereof
|
|
US20230008367A1
(en)
|
2019-09-26 |
2023-01-12 |
Abionyx Pharma Sa |
Compounds useful for treating liver diseases
|
|
US12226446B2
(en)
|
2019-10-11 |
2025-02-18 |
Waterstone Pharmaceuticals(Wuhan) Co., Ltd. |
WS-635 uses thereof in medicine
|
|
AU2020380926A1
(en)
|
2019-11-05 |
2022-05-26 |
Dermira, Inc. |
MrgprX2 antagonists and uses thereof
|
|
CN120698981A
(zh)
|
2019-11-05 |
2025-09-26 |
德米拉公司 |
MrgprX2拮抗剂及其用途
|
|
CN114845709B
(zh)
|
2019-11-05 |
2024-10-01 |
德米拉公司 |
用于治疗炎性病症的mrgprx2拮抗剂
|
|
TW202136237A
(zh)
|
2020-01-06 |
2021-10-01 |
大陸商廣東東陽光藥業有限公司 |
RORγt抑制劑及其製備方法和用途
|
|
TW202136238A
(zh)
|
2020-01-06 |
2021-10-01 |
大陸商廣東東陽光藥業有限公司 |
RORγt抑制劑及其製備方法和用途
|
|
WO2021242970A1
(en)
|
2020-05-29 |
2021-12-02 |
Boulder Bioscience Llc |
Methods for improved endovascular thrombectomy using 3,3'-diindolylmethane
|
|
WO2021257828A1
(en)
|
2020-06-18 |
2021-12-23 |
Shy Therapeutics, Llc |
Substituted thienopyrimidines that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
|
|
EP4171541A1
(en)
|
2020-06-24 |
2023-05-03 |
NeuroBo Pharmaceuticals, Inc. |
Gemcabene for treatment of cytokine storms and viral-induced inflammation
|
|
EP4149471A4
(en)
|
2020-06-30 |
2024-07-10 |
Prosetta Biosciences, Inc. |
ISOQUINOLINE DERIVATIVES, PROCESSES FOR THE SYNTHESIS AND USES THEREOF
|
|
CN113861185B
(zh)
|
2020-06-30 |
2023-04-07 |
广东东阳光药业有限公司 |
2-(取代的嘧啶基)噻唑甲酰胺化合物的盐及其组合物和用途
|
|
EP4180420A4
(en)
|
2020-07-07 |
2024-07-03 |
Sunshine Lake Pharma Co., Ltd. |
PYRROLIDINE AMIDE DERIVATIVE SALT ITS USE
|
|
US11541009B2
(en)
|
2020-09-10 |
2023-01-03 |
Curemark, Llc |
Methods of prophylaxis of coronavirus infection and treatment of coronaviruses
|
|
WO2022061348A1
(en)
|
2020-09-16 |
2022-03-24 |
Biotheryx, Inc. |
Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
TW202231269A
(zh)
|
2020-10-23 |
2022-08-16 |
美商拜歐斯瑞克斯公司 |
Kras蛋白降解劑、其醫藥組合物及其治療應用
|
|
KR20230157936A
(ko)
|
2020-12-14 |
2023-11-17 |
바이오테릭스, 인코포레이티드 |
Pde4 분해인자, 약제학적 조성물, 및 치료학적 적용
|
|
EP4262770A1
(en)
|
2020-12-16 |
2023-10-25 |
Impact Biomedicines, Inc. |
Dosing of fedratinib
|
|
WO2022165000A1
(en)
|
2021-01-27 |
2022-08-04 |
Shy Therapeutics, Llc |
Methods for the treatment of fibrotic disease
|
|
WO2022164997A1
(en)
|
2021-01-27 |
2022-08-04 |
Shy Therapeutics, Llc |
Methods for the treatment of fibrotic disease
|
|
WO2022189856A1
(en)
|
2021-03-08 |
2022-09-15 |
Abionyx Pharma Sa |
Compounds useful for treating liver diseases
|
|
IL305752A
(en)
|
2021-03-10 |
2023-11-01 |
Dice Molecules Sv Inc |
INTEGRIN INHIBITORS OF ALPHA V BETA 6 AND ALPHA V BETA 1 AND THEIR USES
|
|
CA3214087A1
(en)
|
2021-04-09 |
2022-10-13 |
Faming Zhang |
Ws635 uses thereof in medicine
|
|
EP4326721A1
(en)
|
2021-04-22 |
2024-02-28 |
Protego Biopharma, Inc. |
Spirocyclic imidazolidinones and imidazolidinediones for treatment of light chain amyloidosis
|
|
WO2022251533A1
(en)
|
2021-05-27 |
2022-12-01 |
Protego Biopharma, Inc. |
Heteroaryl diamide ire1/xbp1s activators
|
|
WO2022266249A1
(en)
|
2021-06-16 |
2022-12-22 |
Biotheryx, Inc. |
Kras protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
AU2022292649A1
(en)
|
2021-06-16 |
2024-01-04 |
Biotheryx, Inc. |
Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
US20240358722A1
(en)
|
2021-09-14 |
2024-10-31 |
Impact Biomedicines, Inc. |
Methods of administering fedratinib
|
|
WO2023069770A1
(en)
|
2021-10-22 |
2023-04-27 |
Prosetta Biosciences, Inc. |
Novel host-targeted pan-respiratory antiviral small molecule therapeutics
|
|
WO2023102378A1
(en)
|
2021-11-30 |
2023-06-08 |
Kura Oncology, Inc. |
Macrocyclic compounds having farnesyltransferase inhibitory activity
|
|
US11932665B2
(en)
|
2022-01-03 |
2024-03-19 |
Lilac Therapeutics, Inc. |
Cyclic thiol prodrugs
|
|
EP4433040A4
(en)
|
2022-01-03 |
2025-11-12 |
Lilac Therapeutics Inc |
ACYCLIC THIOL PRODRUGS
|
|
WO2023168329A2
(en)
|
2022-03-02 |
2023-09-07 |
Mitopower, Inc. |
Novel prodrugs derived from nicotinic acid and ribose
|
|
GB2619907A
(en)
|
2022-04-01 |
2023-12-27 |
Kanna Health Ltd |
Novel crystalline salt forms of mesembrine
|
|
US12187699B2
(en)
|
2022-04-14 |
2025-01-07 |
Bristol-Myers Squibb Company |
GSPT1 compounds and methods of use of the novel compounds
|
|
AU2023268542A1
(en)
|
2022-05-10 |
2024-11-14 |
Biotheryx, Inc. |
Cdk protein degraders, pharmaceutical compositions, and therapeutic applications
|
|
IL318465A
(en)
|
2022-07-21 |
2025-03-01 |
Antiva Biosciences Inc |
Compositions and dosage forms for the treatment of HPV infection and HPV-induced neoplasia
|
|
EP4584259A1
(en)
|
2022-09-09 |
2025-07-16 |
Innovo Therapeutics, Inc. |
Ck1alpha and dual ck1alpha / gspt1 degrading compounds
|
|
US12171745B2
(en)
|
2022-09-30 |
2024-12-24 |
Boulder Bioscience Llc |
Compositions and methods for treating non-hemorrhagic closed head injury
|
|
EP4608839A1
(en)
|
2022-10-26 |
2025-09-03 |
Protego Biopharma, Inc. |
Spirocycle containing bicyclic heteroaryl compounds
|
|
EP4608834A1
(en)
|
2022-10-26 |
2025-09-03 |
Protego Biopharma, Inc. |
Spirocycle containing pyridine compounds
|
|
EP4608838A1
(en)
|
2022-10-26 |
2025-09-03 |
Protego Biopharma, Inc. |
Spirocycle containing pyridone compounds
|
|
EP4626864A1
(en)
|
2022-11-30 |
2025-10-08 |
Protego Biopharma, Inc. |
Linear heteroaryl diamide ire1/xbp1s activators
|
|
WO2024118810A1
(en)
|
2022-11-30 |
2024-06-06 |
Protego Biopharma, Inc. |
Cyclic pyrazole diamide ire1/xbp1s activators
|
|
WO2025063888A1
(en)
|
2023-09-19 |
2025-03-27 |
Kancure Pte. Ltd. |
Survivin-targeted compounds
|
|
WO2025072423A1
(en)
|
2023-09-27 |
2025-04-03 |
Isosterix, Inc. |
Myst inhibitors
|
|
WO2025072489A2
(en)
|
2023-09-27 |
2025-04-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Analogues of n-lactoyl-phenylalanine, methods of synthesis, and methods of use
|
|
WO2025085416A1
(en)
|
2023-10-16 |
2025-04-24 |
Bristol-Myers Squibb Company |
Gspt1 compounds and methods of use of the compounds
|
|
GB2636969A
(en)
|
2023-11-24 |
2025-07-09 |
Ontrack Therapeutics Ltd |
Novel crystalline salt forms
|
|
WO2025147691A1
(en)
|
2024-01-04 |
2025-07-10 |
Innovo Therapeutics, Inc. |
Compositions and methods for degrading aryl hydrocarbon receptor nuclear translocator protein
|
|
WO2025179161A1
(en)
|
2024-02-21 |
2025-08-28 |
Innovo Therapeutics, Inc. |
Protein degrading compounds
|
|
WO2025201633A1
(en)
|
2024-03-26 |
2025-10-02 |
Chen Gefei |
An agent for reducing amyloid formation
|
|
WO2025231261A1
(en)
|
2024-05-01 |
2025-11-06 |
Protego Biopharma, Inc. |
Bicyclic and heterocyclic amide compounds
|
|
WO2025255341A1
(en)
|
2024-06-05 |
2025-12-11 |
Protego Biopharma, Inc. |
Tetrahydrofuranyl ire1/xbp1s activators
|