|
US4515810A
(en)
*
|
1983-10-06 |
1985-05-07 |
American Cyanamid Company |
Composition of matter
|
|
US5962490A
(en)
|
1987-09-25 |
1999-10-05 |
Texas Biotechnology Corporation |
Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
|
US5004651A
(en)
*
|
1989-01-24 |
1991-04-02 |
Abbott Laboratories |
Stabilizing system for solid dosage forms
|
|
AU645070B2
(en)
*
|
1990-04-10 |
1994-01-06 |
Nb International Technologies |
Use of short chain fatty acid containing lipids to maintain gastrointestinal integrity and function in patients DO NOT SEAL - SEE LETTER DATED 22.03.94
|
|
US6342610B2
(en)
|
1993-05-20 |
2002-01-29 |
Texas Biotechnology Corp. |
N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
|
|
AU749167B2
(en)
|
1997-04-28 |
2002-06-20 |
Encysive Pharmaceuticals Inc. |
Sulfonamides for treatment of endothelin-mediated disorders
|
|
US5783705A
(en)
|
1997-04-28 |
1998-07-21 |
Texas Biotechnology Corporation |
Process of preparing alkali metal salys of hydrophobic sulfonamides
|
|
US6362009B1
(en)
|
1997-11-21 |
2002-03-26 |
Merck & Co., Inc. |
Solid phase synthesis of heterocycles
|
|
US7169410B1
(en)
*
|
1998-05-19 |
2007-01-30 |
Sdg, Inc. |
Targeted liposomal drug delivery system
|
|
US6638977B1
(en)
|
1999-11-19 |
2003-10-28 |
Corvas International, Inc. |
Plasminogen activator inhibitor antagonists
|
|
US6677473B1
(en)
|
1999-11-19 |
2004-01-13 |
Corvas International Inc |
Plasminogen activator inhibitor antagonists
|
|
US7897140B2
(en)
|
1999-12-23 |
2011-03-01 |
Health Research, Inc. |
Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
|
|
AUPR868201A0
(en)
*
|
2001-11-05 |
2001-11-29 |
Thorlock International Limited |
Q-factor switching method and apparatus for detecting nuclear quadrupole and nuclear magnetic resonance signals
|
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
|
JP5082033B2
(ja)
|
2001-12-21 |
2012-11-28 |
エグゼリクシス パテント カンパニー エルエルシー |
Lxrのモジュレーター
|
|
EP1465882B1
(en)
*
|
2001-12-21 |
2011-08-24 |
X-Ceptor Therapeutics, Inc. |
Hetrocyclic modulators of nuclear receptors
|
|
US20040001801A1
(en)
*
|
2002-05-23 |
2004-01-01 |
Corvas International, Inc. |
Conjugates activated by cell surface proteases and therapeutic uses thereof
|
|
EP1517684B1
(en)
|
2002-06-27 |
2009-07-22 |
Health Research, Inc. |
Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
|
|
US7053210B2
(en)
|
2002-07-02 |
2006-05-30 |
Health Research, Inc. |
Efficient synthesis of pyropheophorbide a and its derivatives
|
|
EP2177620B1
(en)
|
2003-03-05 |
2014-11-19 |
Halozyme, Inc. |
Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
US20090123367A1
(en)
*
|
2003-03-05 |
2009-05-14 |
Delfmems |
Soluble Glycosaminoglycanases and Methods of Preparing and Using Soluble Glycosaminoglycanases
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
MXPA05012281A
(es)
*
|
2003-05-14 |
2006-05-19 |
Torreypines Therapeutics Inc |
Compuestos y uso de los mismos en la modulacion beta amiloide.
|
|
AU2004251668B2
(en)
*
|
2003-06-03 |
2008-03-20 |
Triad Therapeutics, Inc |
5-membered heterocycle-based p-38 inhibitors
|
|
US7057100B2
(en)
*
|
2003-06-26 |
2006-06-06 |
The J.C. Robinson Seed Co. |
Inbred corn line W23129
|
|
EP1911754B1
(en)
|
2003-08-13 |
2013-10-09 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
US7420000B2
(en)
|
2003-09-10 |
2008-09-02 |
University Of Southern California |
Amino phosphonate and amino bis-phosphonate derivatives
|
|
US20050203184A1
(en)
|
2003-09-10 |
2005-09-15 |
Petasis Nicos A. |
Benzo lipoxin analogues
|
|
US20050065099A1
(en)
|
2003-09-19 |
2005-03-24 |
Gail Walkinshaw |
Treatment of mitochondrial diseases
|
|
US20050148534A1
(en)
*
|
2003-09-22 |
2005-07-07 |
Castellino Angelo J. |
Small molecule compositions and methods for increasing drug efficiency using compositions thereof
|
|
WO2005090370A1
(en)
*
|
2004-02-05 |
2005-09-29 |
The Regents Of The University Of California |
Pharmacologically active agents containing esterified phosphonates and methods for use thereof
|
|
US8519158B2
(en)
|
2004-03-12 |
2013-08-27 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
|
AU2005244999A1
(en)
|
2004-05-20 |
2005-12-01 |
The Scripps Research Institute |
Transthyretin stabilization
|
|
WO2006009876A2
(en)
*
|
2004-06-17 |
2006-01-26 |
Cengent Therapeutics, Inc. |
Trisubstituted nitrogen modulators of tyrosine phosphatases
|
|
EP1786421A2
(en)
*
|
2004-07-09 |
2007-05-23 |
Cengent Therapeutics, Inc. |
Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases
|
|
MX2007000490A
(es)
|
2004-07-12 |
2007-06-11 |
Idun Pharmaceuticals Inc |
Analogos de tetrapeptido.
|
|
US20060034978A1
(en)
*
|
2004-08-16 |
2006-02-16 |
Grain Processing Corporation |
Aerosol compositions, devices and methods
|
|
WO2006028970A1
(en)
*
|
2004-09-02 |
2006-03-16 |
Cengent Therapeutics, Inc. |
Derivatives of thiazole and thiadiazole inhibitors of tyrosine phosphatases
|
|
CN101060839A
(zh)
|
2004-09-17 |
2007-10-24 |
怀特黑德生物医学研究院 |
抑制α-突触核蛋白毒性的化合物、组合物和方法
|
|
EP1831235B1
(en)
|
2004-12-16 |
2013-02-20 |
The Regents of The University of California |
Lung-targeted drugs
|
|
JP2008524331A
(ja)
|
2004-12-21 |
2008-07-10 |
武田薬品工業株式会社 |
ジペプチジルペプチダーゼ阻害剤
|
|
EP1866319B1
(en)
|
2005-04-01 |
2011-11-23 |
The Regents of The University of California |
Phosphono-pent-2-en-1-yl nucleosides and analogs
|
|
US20090156545A1
(en)
*
|
2005-04-01 |
2009-06-18 |
Hostetler Karl Y |
Substituted Phosphate Esters of Nucleoside Phosphonates
|
|
CN101309688B
(zh)
*
|
2005-05-23 |
2016-06-22 |
自然选择国际公司 |
持续释放β-丙氨酸的组合物和方法
|
|
BRPI0609191B8
(pt)
*
|
2005-06-17 |
2021-05-25 |
Ligand Pharm Inc |
métodos e compostos moduladores de receptor de androgênio
|
|
US20100098640A1
(en)
*
|
2005-06-20 |
2010-04-22 |
Cohen Seth M |
Multidentate Pyrone-Derived Chelators for Medicinal Imaging and Chelation
|
|
US20080058282A1
(en)
|
2005-08-30 |
2008-03-06 |
Fallon Joan M |
Use of lactulose in the treatment of autism
|
|
US8492428B2
(en)
*
|
2005-09-20 |
2013-07-23 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
|
US8119655B2
(en)
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
WO2007076160A2
(en)
*
|
2005-12-28 |
2007-07-05 |
Acidophil Llc |
C-10 carbamates of taxanes
|
|
RU2008136317A
(ru)
*
|
2006-03-13 |
2010-04-20 |
Инсайсив Фармасьютикалз, Инк. (US) |
Способы и композиции для лечения диагностикой сердечной недостаточности
|
|
AU2007225088B2
(en)
|
2006-03-13 |
2012-09-13 |
Kyorin Pharmaceutical Co., Ltd |
Aminoquinolones as GSK-3 inhibitors
|
|
US20080076812A1
(en)
*
|
2006-03-13 |
2008-03-27 |
Jinling Chen |
Formulations of sitaxsentan sodium
|
|
CA2647543A1
(en)
*
|
2006-03-29 |
2007-11-08 |
Foldrx Pharmaceuticals, Inc. |
Inhibition of alpha-synuclein toxicity
|
|
US20080026061A1
(en)
*
|
2006-06-22 |
2008-01-31 |
Reichwein John F |
Crystalline N-(4-chloro-3-methyl-5-isoxazolyl)-2-[2-methyl-4.5-(methylenedioxy)phenylacetyl]-thiophene-3-sulfonamide
|
|
SG170032A1
(en)
|
2006-08-28 |
2011-04-29 |
Kyowa Hakko Kirin Co Ltd |
Antagonistic human light-specific human monoclonal antibodies
|
|
WO2008036379A2
(en)
|
2006-09-21 |
2008-03-27 |
Activx Biosciences, Inc. |
Serine hydrolase inhibitors
|
|
JP2010505961A
(ja)
|
2006-10-09 |
2010-02-25 |
タケダ サン ディエゴ インコーポレイテッド |
キナーゼ阻害剤
|
|
AU2007313961A1
(en)
|
2006-10-09 |
2008-05-08 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
|
US20080103189A1
(en)
|
2006-10-19 |
2008-05-01 |
Auspex Pharmaceuticals, Inc. |
Preparation and utility of substituted indoles
|
|
HRP20130159T1
(hr)
|
2006-10-19 |
2013-03-31 |
Genzyme Corporation |
Roskovitin, namijenjen lijeäśenju izvjesnih cistiäśnih bolesti
|
|
EP2089359A2
(en)
|
2006-10-31 |
2009-08-19 |
Takeda Pharmaceutical Company Limited |
Mapk/erk kinase inhibitors
|
|
US20100137421A1
(en)
*
|
2006-11-08 |
2010-06-03 |
Emmanuel Theodorakis |
Small molecule therapeutics, synthesis of analogues and derivatives and methods of use
|
|
KR20090086115A
(ko)
*
|
2006-12-22 |
2009-08-10 |
엔싸이시브 파마슈티칼즈 인코퍼레이티드 |
C3a 수용체의 조정제 및 이의 사용 방법
|
|
WO2008106167A1
(en)
*
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the treatment of liver diseases
|
|
WO2008106166A2
(en)
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Methods for the treatment of liver diseases using specified matrix metalloproteinase (mmp) inhibitors
|
|
PL2125698T3
(pl)
|
2007-03-15 |
2017-03-31 |
Auspex Pharmaceuticals, Inc. |
Deuterowana wenlafaksyna-d9
|
|
AU2008274941A1
(en)
*
|
2007-07-12 |
2009-01-15 |
Tragara Pharmaceuticals, Inc. |
Methods and compositions for the treatment of cancer, tumors, and tumor-related disorders
|
|
BRPI0816798A2
(pt)
*
|
2007-09-11 |
2016-10-11 |
Activx Biosciences Inc |
composto, composição farmacêutica, métodos para inibir a ação do glicogênio sintase cinase-3, e para tratar, prevenir ou melhorar uma doença, uso de um composto, e, artigo de fabricação
|
|
KR101597841B1
(ko)
|
2007-09-12 |
2016-02-26 |
교린 세이야꾸 가부시키 가이샤 |
Gsk-3 억제제로서의 스피로시클릭 아미노퀴놀론
|
|
EP2205241B1
(en)
|
2007-09-25 |
2014-05-21 |
Takeda Pharmaceutical Company Limited |
Polo-like kinase inhibitors
|
|
US20090264421A1
(en)
*
|
2007-10-05 |
2009-10-22 |
Bible Keith C |
Methods and Compositions for Treating Cancer
|
|
ES2436266T3
(es)
|
2007-11-08 |
2013-12-30 |
Ambit Biosciences Corporation |
Métodos para administrar N-(5-terc-butil-isoxazol-3-il)-N'-{4-[7-(2-morfolin-4-il-etoxi)imidazo[2,1-b][1,3]benzotiazol-2-il]fenil}urea para tratar enfermedades proliferativas
|
|
AU2008327615B2
(en)
*
|
2007-11-21 |
2014-08-21 |
Pharmaxis Ltd. |
Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor
|
|
EP2222636B1
(en)
|
2007-12-21 |
2013-04-10 |
Ligand Pharmaceuticals Inc. |
Selective androgen receptor modulators (sarms) and uses thereof
|
|
US8658163B2
(en)
|
2008-03-13 |
2014-02-25 |
Curemark Llc |
Compositions and use thereof for treating symptoms of preeclampsia
|
|
CN106146484A
(zh)
|
2008-03-17 |
2016-11-23 |
埃姆比特生物科学公司 |
喹唑啉衍生物作为raf激酶调节剂以及它们的方法和用途
|
|
TW200946541A
(en)
*
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
|
US8084025B2
(en)
|
2008-04-18 |
2011-12-27 |
Curemark Llc |
Method for the treatment of the symptoms of drug and alcohol addiction
|
|
MX2010012514A
(es)
*
|
2008-05-20 |
2011-05-30 |
Cerenis Therapeutics S A |
Niacina y un medicamento nsaid para tratamiento combinado.
|
|
WO2010008847A2
(en)
|
2008-06-24 |
2010-01-21 |
Takeda Pharmaceutical Company Limited |
Pi3k/m tor inhibitors
|
|
ES2732453T3
(es)
|
2008-07-01 |
2019-11-22 |
Curemark Llc |
Métodos y composiciones para el tratamiento de síntomas de trastornos neurológicos y de salud mental
|
|
NZ593831A
(en)
|
2009-01-06 |
2013-09-27 |
Curelon Llc |
Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus on surfaces
|
|
KR20170005191A
(ko)
|
2009-01-06 |
2017-01-11 |
큐어론 엘엘씨 |
이. 콜라이에 의한 구강 감염의 치료 또는 예방을 위한 조성물 및 방법
|
|
WO2010088450A2
(en)
|
2009-01-30 |
2010-08-05 |
Celladon Corporation |
Methods for treating diseases associated with the modulation of serca
|
|
US8568793B2
(en)
|
2009-02-11 |
2013-10-29 |
Hope Medical Enterprises, Inc. |
Sodium nitrite-containing pharmaceutical compositions
|
|
JP5746981B2
(ja)
|
2009-02-27 |
2015-07-08 |
アムビト ビオスシエンセス コルポラチオン |
Jakキナーゼ調節キナゾリン誘導体、及びその使用方法
|
|
EP2403860B1
(en)
|
2009-03-04 |
2015-11-04 |
IDENIX Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole as hcv polymerase inhibitors
|
|
CA2754909A1
(en)
|
2009-03-11 |
2010-09-16 |
Ambit Biosciences Corp. |
Combination of an indazolylaminopyrrolotriazine and taxane for cancer treatment
|
|
BRPI1013698A2
(pt)
|
2009-03-23 |
2016-04-26 |
Ambit Biosciences Corp |
métodos para tratamento com o uso de terapia de combinação
|
|
EP2415767B1
(en)
|
2009-03-27 |
2014-09-03 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-ribose) Polymerase (PARP) Inhibitors
|
|
WO2010110686A1
(en)
|
2009-03-27 |
2010-09-30 |
Pathway Therapeutics Limited |
Pyrimidinyl and 1,3,5 triazinyl benzimidazoles and their use in cancer therapy
|
|
EP2411387B1
(en)
|
2009-03-27 |
2015-08-19 |
VetDC, Inc. |
Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
|
US9056050B2
(en)
|
2009-04-13 |
2015-06-16 |
Curemark Llc |
Enzyme delivery systems and methods of preparation and use
|
|
KR20120013403A
(ko)
|
2009-04-22 |
2012-02-14 |
액시킨 파마수티컬스 인코포레이티드 |
2,5-이치환된 아릴설폰아마이드 ccr3 길항제
|
|
US8399456B2
(en)
|
2009-04-22 |
2013-03-19 |
Axikin Pharmaceuticals, Inc. |
2,5-disubstituted arylsulfonamide CCR3 antagonists
|
|
MX2011011141A
(es)
|
2009-04-22 |
2012-02-13 |
Axikin Pharmaceuticals Inc |
Antagonistas ccr3 arisulfonamida.
|
|
SMT202000092T1
(it)
|
2009-05-14 |
2020-05-08 |
Ambit Biosciences Corp |
Formulazione essiccata a spruzzo o liofilizzata di ac220
|
|
TW201105662A
(en)
|
2009-07-07 |
2011-02-16 |
Pathway Therapeutics Ltd |
Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy
|
|
WO2011005841A1
(en)
|
2009-07-08 |
2011-01-13 |
Hope Medical Enterprises, Inc. Dba Hope Pharmaceuticals |
Sodium thiosulfate-containing pharmaceutical compositions
|
|
US8404728B2
(en)
|
2009-07-30 |
2013-03-26 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
|
JP5715625B2
(ja)
|
2009-07-30 |
2015-05-07 |
武田薬品工業株式会社 |
ポリ(adp−リボース)ポリメラーゼ(parp)阻害剤
|
|
US9284307B2
(en)
|
2009-08-05 |
2016-03-15 |
Idenix Pharmaceuticals Llc |
Macrocyclic serine protease inhibitors
|
|
KR20120099378A
(ko)
|
2009-08-14 |
2012-09-10 |
닛뽕 케미파 가부시키가이샤 |
염증 또는 에너지 대사/생산 관련 질환의 치료 또는 예방을 위한 ppar 델타 리간드의 용도
|
|
WO2011041293A1
(en)
|
2009-09-30 |
2011-04-07 |
Takeda Pharmaceutical Company Limited |
Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
|
|
TW201120037A
(en)
|
2009-10-26 |
2011-06-16 |
Sunesis Pharmaceuticals Inc |
Compounds and methods for treatment of cancer
|
|
CA2779736A1
(en)
*
|
2009-11-03 |
2011-05-12 |
Bernard Charles Sherman |
Stable pharmaceutical formulations comprising lubiprostone
|
|
WO2011056764A1
(en)
|
2009-11-05 |
2011-05-12 |
Ambit Biosciences Corp. |
Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles
|
|
US8871460B2
(en)
|
2009-11-09 |
2014-10-28 |
Neurogenetic Pharmaceuticals, Inc. |
Gamma-secretase modulatory compounds, methods for identifying same, and uses therefor
|
|
WO2011069002A1
(en)
|
2009-12-02 |
2011-06-09 |
Alquest Therapeutics, Inc. |
Organoselenium compounds and uses thereof
|
|
RU2554087C2
(ru)
|
2009-12-18 |
2015-06-27 |
Айденикс Фармасьютикалз, Инк. |
5,5-конденсированные ариленовые или гетероариленовые ингибиторы вируса гепатита с
|
|
WO2011079313A1
(en)
*
|
2009-12-23 |
2011-06-30 |
Map Pharmaceuticals, Inc. |
Novel ergoline analogs
|
|
CN103664873B
(zh)
*
|
2009-12-30 |
2016-06-15 |
深圳信立泰药业股份有限公司 |
作为二肽基肽酶iv(dpp-iv)抑制剂的3-(3-氨基哌啶-1-基)-5-氧代-1,2,4-三嗪衍生物
|
|
ES2445917T3
(es)
|
2010-02-03 |
2014-03-06 |
Takeda Pharmaceutical Company Limited |
Inhibidores de quinasa 1 reguladora de la señal de apoptosis
|
|
AU2011223873B2
(en)
|
2010-03-02 |
2015-06-25 |
Axikin Pharmaceuticals, Inc. |
Isotopically enriched arylsulfonamide CCR3 antagonists
|
|
WO2011112689A2
(en)
|
2010-03-11 |
2011-09-15 |
Ambit Biosciences Corp. |
Saltz of an indazolylpyrrolotriazine
|
|
US8741894B2
(en)
|
2010-03-17 |
2014-06-03 |
Axikin Pharmaceuticals, Inc. |
Arylsulfonamide CCR3 antagonists
|
|
MX341050B
(es)
|
2010-04-07 |
2016-08-05 |
Celgene Corp * |
Metodos para tratar infeccion viral respiratoria.
|
|
CA2801003A1
(en)
|
2010-06-01 |
2011-12-08 |
Biotheryx, Inc. |
Methods of treating hematologic malignancies using 6-cyclohexyl-1-hydroxy-4-methyl-2(1h)-pyridone
|
|
WO2011153197A1
(en)
|
2010-06-01 |
2011-12-08 |
Biotheryx, Inc. |
Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating proliferative diseases
|
|
CA2801778C
(en)
|
2010-06-07 |
2018-06-05 |
Novomedix, Llc |
Furanyl compounds and the use thereof
|
|
JP6069661B2
(ja)
|
2010-06-24 |
2017-02-01 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
種々のアミロイドβペプチドアロフォームレベルの調節における組成物及びその使用
|
|
WO2012012370A1
(en)
|
2010-07-19 |
2012-01-26 |
Summa Health System |
Vitamin c and chromium-free vitamin k, and compositions thereof for treating an nfkb-mediated condition or disease
|
|
US20140200270A1
(en)
|
2013-01-11 |
2014-07-17 |
Summa Health System |
Vitamins c and k for treating polycystic diseases
|
|
WO2012030918A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
Adenosine a3 receptor modulating compounds and methods of use thereof
|
|
MX2013002383A
(es)
|
2010-09-01 |
2013-07-05 |
Ambit Biosciences Corp |
Sales bromhidrato de una pirazolilaminoquinazolina.
|
|
US20130317045A1
(en)
|
2010-09-01 |
2013-11-28 |
Ambit Biosciences Corporation |
Thienopyridine and thienopyrimidine compounds and methods of use thereof
|
|
WO2012030910A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
2-cycloquinazoline derivatives and methods of use thereof
|
|
EP2611448A1
(en)
|
2010-09-01 |
2013-07-10 |
Ambit Biosciences Corporation |
7-cyclylquinazoline derivatives and methods of use thereof
|
|
WO2012030914A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Boisciences Corporation |
4-azolylaminoquinazoline derivatives and methods of use thereof
|
|
EP2663553B1
(en)
|
2010-09-01 |
2015-08-26 |
Ambit Biosciences Corporation |
Quinoline and isoquinoline derivatives for use as jak modulators
|
|
EP2611809A1
(en)
|
2010-09-01 |
2013-07-10 |
Ambit Biosciences Corporation |
Azolopyridine and azolopyrimidine compounds and methods of use thereof
|
|
ES2579942T3
(es)
|
2010-09-01 |
2016-08-17 |
Ambit Biosciences Corporation |
Pirazolilaminoquinazolina ópticamente activa y composiciones farmacéuticas y métodos de uso de la misma
|
|
CA2810024A1
(en)
|
2010-09-01 |
2012-03-08 |
Ambit Biosciences Corporation |
Quinazoline compounds and methods of use thereof
|
|
US8859502B2
(en)
|
2010-09-13 |
2014-10-14 |
Celgene Corporation |
Therapy for MLL-rearranged leukemia
|
|
WO2012044641A1
(en)
|
2010-09-29 |
2012-04-05 |
Pathway Therapeutics Inc. |
1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
|
CA2814011A1
(en)
|
2010-10-11 |
2012-04-19 |
Axikin Pharmaceuticals, Inc. |
Salts of arylsulfonamide ccr3 antagonists
|
|
WO2012080050A1
(en)
|
2010-12-14 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Solid forms of a phenoxybenzenesulfonyl compound
|
|
AR085352A1
(es)
|
2011-02-10 |
2013-09-25 |
Idenix Pharmaceuticals Inc |
Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv
|
|
US20140088103A1
(en)
|
2011-03-28 |
2014-03-27 |
Mei Pharma, Inc. |
(fused ring arylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
|
|
EP2691384B1
(en)
|
2011-03-28 |
2016-10-26 |
MEI Pharma, Inc. |
(alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions containing them, and these compounds for use in treating proliferative diseases
|
|
WO2012135175A1
(en)
|
2011-03-28 |
2012-10-04 |
Pathway Therapeutics Inc. |
(alpha-substituted cycloalkylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases
|
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
|
WO2012145651A2
(en)
|
2011-04-21 |
2012-10-26 |
Curemark, Llc |
Compounds for the treatment of neuropsychiatric disorders
|
|
KR20140042868A
(ko)
|
2011-06-23 |
2014-04-07 |
맵 파마슈티컬스, 인코포레이티드 |
신규한 플루오로에르골린 유사체
|
|
WO2013022872A1
(en)
|
2011-08-10 |
2013-02-14 |
Celgene Corporation |
Gene methylation biomarkers and methods of use thereof
|
|
UA124239U
(uk)
|
2011-09-02 |
2018-03-26 |
Общєство С Огранічєной Отвєтствєностью "Новамєдіка" |
Спосіб лікування раку молочної залози
|
|
WO2013037482A1
(en)
|
2011-09-15 |
2013-03-21 |
Phenex Pharmaceuticals Ag |
Farnesoid x receptor agonists for cancer treatment and prevention
|
|
CN104114182A
(zh)
|
2011-09-23 |
2014-10-22 |
细胞基因公司 |
罗米地辛和5-阿扎胞苷在治疗淋巴瘤中的应用
|
|
US20130244950A1
(en)
|
2011-09-26 |
2013-09-19 |
Celgene Corporation |
Combination therapy for chemoresistant cancers
|
|
TW201700103A
(zh)
|
2011-11-01 |
2017-01-01 |
西建公司 |
利用胞嘧啶核苷類似物之口服配方治療癌症的方法
|
|
WO2013085902A1
(en)
|
2011-12-05 |
2013-06-13 |
The University Of Texas M.D. |
Combination therapy methods for treating an inflammatory breast cancer
|
|
AU2012355982A1
(en)
|
2011-12-19 |
2014-07-10 |
Map Pharmaceuticals, Inc. |
Novel iso-ergoline derivatives
|
|
EP2793583A4
(en)
|
2011-12-21 |
2015-08-12 |
Map Pharmaceuticals Inc |
NOVEL NEUROMODULATORY CONNECTIONS
|
|
WO2013130600A1
(en)
|
2012-02-29 |
2013-09-06 |
Ambit Biosciences Corporation |
Solid forms comprising optically active pyrazolylaminoquinazoline, compositions thereof, and uses therewith
|
|
IN2012DE00661A
(enExample)
|
2012-03-07 |
2015-08-21 |
Univ Delhi |
|
|
WO2013138613A1
(en)
|
2012-03-16 |
2013-09-19 |
Axikin Pharmaceuticals, Inc. |
3,5-diaminopyrazole kinase inhibitors
|
|
WO2013148919A1
(en)
|
2012-03-30 |
2013-10-03 |
The Regents Of The University Of Colorado, A Body Corporate |
Treatment of multiple myeloma
|
|
RS57086B1
(sr)
|
2012-05-02 |
2018-06-29 |
Boehringer Ingelheim Int |
Supstituisani 3-haloalilamin inhibitori ssao i njihova primena
|
|
US10350278B2
(en)
|
2012-05-30 |
2019-07-16 |
Curemark, Llc |
Methods of treating Celiac disease
|
|
WO2013187965A1
(en)
|
2012-06-14 |
2013-12-19 |
Mayo Foundation For Medical Education And Research |
Pyrazole derivatives as inhibitors of stat3
|
|
US9012640B2
(en)
|
2012-06-22 |
2015-04-21 |
Map Pharmaceuticals, Inc. |
Cabergoline derivatives
|
|
US8551535B1
(en)
|
2012-08-06 |
2013-10-08 |
Sarah McCann |
Homeopathic remedies and methods for enhancing weight loss
|
|
US9074186B2
(en)
|
2012-08-15 |
2015-07-07 |
Boston Medical Center Corporation |
Production of red blood cells and platelets from stem cells
|
|
AU2013202506B2
(en)
|
2012-09-07 |
2015-06-18 |
Celgene Corporation |
Resistance biomarkers for hdac inhibitors
|
|
CA2881129A1
(en)
|
2012-09-07 |
2014-03-13 |
Axikin Pharmaceuticals, Inc. |
Isotopically enriched arylsulfonamide ccr3 antagonists
|
|
WO2014055647A1
(en)
|
2012-10-03 |
2014-04-10 |
Mei Pharma, Inc. |
(sulfinyl and sulfonyl benzimidazolyl) pyrimidines and triazines, pharmaceutical compositions thereof, and their use for treating proliferative diseases
|
|
US20150272924A1
(en)
|
2012-11-08 |
2015-10-01 |
Summa Health System |
Vitamin c, vitamin k, a polyphenol, and combinations thereof for wound healing
|
|
AU2013202507B9
(en)
|
2012-11-14 |
2015-08-13 |
Celgene Corporation |
Inhibition of drug resistant cancer cells
|
|
WO2014085633A1
(en)
|
2012-11-30 |
2014-06-05 |
Novomedix, Llc |
Substituted biaryl sulfonamides and the use thereof
|
|
EP2934143A4
(en)
|
2012-12-21 |
2016-06-15 |
Map Pharmaceuticals Inc |
NOVEL DERIVATIVES OF METHYSERGIDE
|
|
US9169214B2
(en)
|
2012-12-21 |
2015-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
|
|
WO2014130908A1
(en)
|
2013-02-22 |
2014-08-28 |
University Of Southern California |
Methods for treatment of ophthalmic diseases and disorders
|
|
EP2968296B1
(en)
|
2013-03-12 |
2020-09-02 |
The Regents of the University of California |
Gamma-secretase modulators
|
|
EP3935944A1
(en)
|
2013-03-15 |
2022-01-12 |
University Of Southern California, USC Stevens |
Compounds for the treatment of musculoskeletal diseases
|
|
TWI642677B
(zh)
|
2013-03-15 |
2018-12-01 |
美國加利福尼亞大學董事會 |
非環狀核苷膦酸二酯
|
|
US9968627B2
(en)
|
2013-03-26 |
2018-05-15 |
Celgene Corporation |
Solid forms comprising 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one and a coformer, compositions and methods of use thereof
|
|
EP3003390B1
(en)
|
2013-06-06 |
2021-07-07 |
Pierre Fabre Médicament |
Anti-c10orf54 antibodies and uses thereof
|
|
EP2815749A1
(en)
|
2013-06-20 |
2014-12-24 |
IP Gesellschaft für Management mbH |
Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
|
|
NZ631142A
(en)
|
2013-09-18 |
2016-03-31 |
Axikin Pharmaceuticals Inc |
Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors
|
|
EP3046924A1
(en)
|
2013-09-20 |
2016-07-27 |
IDENIX Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
|
WO2015051336A1
(en)
|
2013-10-03 |
2015-04-09 |
David Wise |
Compositions and methods for treating pelvic pain and other conditions
|
|
CN104725359B
(zh)
|
2013-12-20 |
2017-05-03 |
广东东阳光药业有限公司 |
取代的哌嗪化合物及其使用方法和用途
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
|
AU2015231215B2
(en)
|
2014-03-20 |
2019-07-18 |
Capella Therapeutics, Inc. |
Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer
|
|
ES2891734T3
(es)
|
2014-03-20 |
2022-01-31 |
Capella Therapeutics Inc |
Derivados de bencimidazol como inhibidores de tirosina quinasa ERBB para el tratamiento del cáncer
|
|
US9399637B2
(en)
|
2014-03-28 |
2016-07-26 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
|
US20170100448A1
(en)
|
2014-05-12 |
2017-04-13 |
Conatus Pharmaceuticals, Inc. |
Treatment of the complications of chronic liver disease with caspase inhibitors
|
|
WO2015195634A1
(en)
|
2014-06-17 |
2015-12-23 |
Celgne Corporation |
Methods for treating epstein-barr virus (ebv) associated cancers using oral formulations of 5-azacytidine
|
|
WO2015195786A2
(en)
|
2014-06-17 |
2015-12-23 |
Celgene Corporation |
Methods for treating cancers using oral formulations of cytidine analogs
|
|
US9527815B2
(en)
|
2014-06-18 |
2016-12-27 |
Biotheryx, Inc. |
Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating inflammatory, neurodegenerative, or immune-mediated diseases
|
|
US9499514B2
(en)
|
2014-07-11 |
2016-11-22 |
Celgene Corporation |
Antiproliferative compounds and methods of use thereof
|
|
WO2016025129A1
(en)
|
2014-08-14 |
2016-02-18 |
Alhamadsheh Mamoun M |
Conjugation of pharmaceutically active agents with transthyretin ligands through adjustable linkers to increase serum half-life
|
|
BR112017005111B1
(pt)
|
2014-09-15 |
2023-02-14 |
The Regents Of The University Of California |
Compostos análogos de nucleotídeo acíclico, composição farmacêutica contendo tais compostos, e usos da composição no tratamento de uma infecção por papilomavírus
|
|
US20170354639A1
(en)
|
2014-10-24 |
2017-12-14 |
Biogen Ma Inc. |
Diterpenoid derivatives and methods of use thereof
|
|
AU2015338946B2
(en)
|
2014-10-31 |
2020-06-11 |
The General Hospital Corporation |
Potent gamma-secretase modulators
|
|
TN2017000246A1
(en)
|
2014-12-11 |
2018-10-19 |
Pf Medicament |
Anti-c10orf54 antibodies and uses thereof
|
|
MX373817B
(es)
|
2014-12-23 |
2020-03-23 |
Axikin Pharmaceuticals Inc |
Inhibidores de 3,5-diaminopirazol quinasa.
|
|
BR112017015487A2
(pt)
|
2015-01-20 |
2018-01-30 |
Xoc Pharmaceuticals Inc |
Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
|
|
CA2974113A1
(en)
|
2015-01-20 |
2016-07-28 |
Xoc Pharmaceuticals, Inc. |
Isoergoline compounds and uses thereof
|
|
EP4137157A1
(en)
|
2015-03-03 |
2023-02-22 |
Kymab Limited |
Antibodies, uses and methods
|
|
CA2980297A1
(en)
|
2015-03-20 |
2016-09-29 |
Syndax Pharmaceuticals, Inc. |
Combination of hdac inhibitor and anti-pd-1 antibody for treatment of cancer
|
|
WO2016176617A2
(en)
|
2015-04-29 |
2016-11-03 |
New York University |
Method for treating high-grade gliomas
|
|
CN107921032B
(zh)
|
2015-06-23 |
2021-09-24 |
纽罗克里生物科学有限公司 |
用于治疗神经学疾病或病症的vmat2抑制剂
|
|
KR102246710B1
(ko)
|
2015-08-17 |
2021-04-30 |
쿠라 온콜로지, 인크. |
파르네실전달효소 억제제를 이용하여 암환자를 치료하는 방법
|
|
KR102631377B1
(ko)
|
2015-09-02 |
2024-01-29 |
신닥스 파마슈티컬스, 인크. |
조합 요법을 위한 환자의 선별
|
|
EP3347097B1
(en)
|
2015-09-11 |
2021-02-24 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora
|
|
EP3875462A1
(en)
|
2015-09-15 |
2021-09-08 |
The Regents of The University of California |
Nucleotide analogs
|
|
WO2017050803A1
(en)
|
2015-09-25 |
2017-03-30 |
Universität Duisburg-Essen |
Agents inhibiting kallikrein-8 for use in the prevention or treatment of alzheimer's disease
|
|
MX381258B
(es)
|
2015-10-30 |
2025-03-12 |
Neurocrine Biosciences Inc |
Sales de valbenazina y polimorfos de las mismas.
|
|
WO2017079566A1
(en)
|
2015-11-05 |
2017-05-11 |
Conatus Pharmaceuticals, Inc. |
Caspase inhibitors for use in the treatment of liver cancer
|
|
US10112924B2
(en)
|
2015-12-02 |
2018-10-30 |
Astraea Therapeutics, Inc. |
Piperdinyl nociceptin receptor compounds
|
|
CN108883103A
(zh)
|
2015-12-02 |
2018-11-23 |
阿斯特来亚治疗有限责任公司 |
哌啶基痛敏肽受体化合物
|
|
CN121045173A
(zh)
|
2015-12-23 |
2025-12-02 |
纽罗克里生物科学有限公司 |
制备3-异丁基-9,10-二甲氧基-六氢-1H-吡啶并[2,1-a]异喹啉-2-基2-氨基-3-甲基丁酸酯的盐的方法
|
|
EP3397251A1
(en)
|
2015-12-31 |
2018-11-07 |
Conatus Pharmaceuticals, Inc. |
Methods of using caspase inhibitors in treatment of liver disease
|
|
WO2017120422A1
(en)
|
2016-01-08 |
2017-07-13 |
Celgene Corporation |
Antiproliferative compounds, and their pharmaceutical compositions and uses
|
|
WO2017151836A1
(en)
|
2016-03-04 |
2017-09-08 |
East Carolina University |
J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders
|
|
WO2017156191A1
(en)
|
2016-03-08 |
2017-09-14 |
Los Gatos Pharmaceuticals, Inc. |
Composite nanoparticles and uses thereof
|
|
JP2019513151A
(ja)
|
2016-03-08 |
2019-05-23 |
ロス ガトス ファーマスーティカルズ, インク.Los Gatos Pharmaceuticals, Inc. |
カンプトテシン誘導体及びその使用
|
|
AU2017250086A1
(en)
|
2016-04-11 |
2018-09-20 |
Clexio Biosciences Ltd. |
Deuterated ketamine derivatives
|
|
WO2017180794A1
(en)
|
2016-04-13 |
2017-10-19 |
Skyline Antiinfectives, Inc. |
Deuterated o-sulfated beta-lactam hydroxamic acids and deuterated n-sulfated beta-lactams
|
|
WO2017184968A1
(en)
|
2016-04-22 |
2017-10-26 |
Kura Oncology, Inc. |
Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors
|
|
WO2017194789A1
(en)
|
2016-05-13 |
2017-11-16 |
Institut Pasteur |
Inhibition of beta-2 nicotinic acetylcholine receptors to treat alzheimer's disease pathology
|
|
TWI753910B
(zh)
|
2016-05-16 |
2022-02-01 |
美商拜歐斯瑞克斯公司 |
吡啶硫酮、其醫藥組合物及其治療增生性、炎性、神經退化性或免疫介導疾病之治療用途
|
|
WO2018013689A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, method of preparation and use thereof
|
|
WO2018013693A1
(en)
|
2016-07-13 |
2018-01-18 |
Celgene Corporation |
Solid dispersions and cocrystals comprising 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione compositions and methods of use thereof
|
|
WO2018035281A1
(en)
|
2016-08-17 |
2018-02-22 |
North Carolina State University |
Northern-southern route to synthesis of bacteriochlorins
|
|
MA46285A
(fr)
|
2016-09-19 |
2019-07-31 |
Mei Pharma Inc |
Polythérapie
|
|
EP3838275A1
(en)
|
2016-11-03 |
2021-06-23 |
Kura Oncology, Inc. |
Farnesyltransferase inhibitors for use in methods of treating cancer
|
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
CA3042055A1
(en)
|
2016-11-09 |
2018-05-17 |
Novomedix, Llc |
Nitrite salts of 1,1-dimethylbiguanide, pharmaceutical compositions, and methods of use
|
|
WO2018089692A1
(en)
|
2016-11-09 |
2018-05-17 |
Phloronol, Inc. |
Eckol derivatives, methods of synthesis and uses thereof
|
|
US10836774B2
(en)
|
2016-11-30 |
2020-11-17 |
North Carolina State University |
Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds
|
|
JP7105774B2
(ja)
|
2016-12-01 |
2022-07-25 |
イグナイタ インコーポレイテッド |
がん治療のための方法
|
|
TW202515564A
(zh)
|
2016-12-02 |
2025-04-16 |
美商紐羅克里生物科學有限公司 |
戊苯那嗪(valbenazine)於治療精神分裂症或情感性精神分裂症之用途
|
|
US20200093808A1
(en)
|
2017-01-27 |
2020-03-26 |
Neurocrine Biosciences, Inc. |
Methods for the Administration of Certain VMAT2 Inhibitors
|
|
WO2018141063A1
(en)
|
2017-02-02 |
2018-08-09 |
Mcmaster University |
Bicarbonate as a potentiator for antimicrobial agents
|
|
CN110381940B
(zh)
|
2017-02-17 |
2023-07-21 |
文涵治疗有限公司 |
Ag-10的制备方法、其中间体及其盐
|
|
TWI693074B
(zh)
|
2017-02-21 |
2020-05-11 |
美商庫拉腫瘤技術股份有限公司 |
以法呢基轉移酶(farnesyltransferase)抑制劑治療癌症之方法
|
|
US10137121B2
(en)
|
2017-02-21 |
2018-11-27 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
WO2018164996A1
(en)
|
2017-03-06 |
2018-09-13 |
Neurocrine Biosciences, Inc. |
Dosing regimen for valbenazine
|
|
BR112019020464A2
(pt)
|
2017-03-30 |
2020-04-28 |
Xw Laboratories Inc. |
compostos derivados de heteroarila bicíclica, composição farmacêutica compreendendo os ditos compostos, adesivo transdérmico compreendendo a dita composição e uso terapêutico dos compostos e composição
|
|
US12226464B2
(en)
|
2017-04-10 |
2025-02-18 |
Curemark, Llc |
Compositions for treating addiction
|
|
JP6963164B2
(ja)
|
2017-04-24 |
2021-11-05 |
チンワー ユニバーシティー |
アポトーシス誘導及び抗感染治療における自己誘導物質関連経路の応用
|
|
WO2018200605A1
(en)
|
2017-04-26 |
2018-11-01 |
Neurocrine Biosciences, Inc. |
Use of valbenazine for treating levodopa-induced dyskinesia
|
|
JOP20190219A1
(ar)
|
2017-05-09 |
2019-09-22 |
Cardix Therapeutics LLC |
تركيبات صيدلانية وطرق لعلاج أمراض القلب والأوعية الدموية
|
|
US10085999B1
(en)
|
2017-05-10 |
2018-10-02 |
Arixa Pharmaceuticals, Inc. |
Beta-lactamase inhibitors and uses thereof
|
|
CA3064274A1
(en)
|
2017-06-01 |
2018-12-06 |
Xoc Pharmaceuticals, Inc. |
Ergoline derivatives for use in medicine
|
|
EP3645029B1
(en)
|
2017-06-26 |
2023-01-18 |
Institut Pasteur |
Treatments to eliminate hiv reservoirs and reduce viral load
|
|
KR20200051601A
(ko)
|
2017-08-07 |
2020-05-13 |
쿠라 온콜로지, 인크. |
파르네실전달효소 억제제를 이용하여 암을 치료하는 방법
|
|
US10806730B2
(en)
|
2017-08-07 |
2020-10-20 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
EP3668837B1
(en)
|
2017-08-17 |
2022-07-06 |
XWPharma Ltd. |
Preparation and uses of reactive oxygen species scavenger derivatives
|
|
EP4265257A1
(en)
|
2017-09-01 |
2023-10-25 |
East Carolina University |
Combination of a j-series prostaglandin-ethanolamide and a checkpoint inhibitor for use in treating cancer
|
|
EP3988561B1
(en)
|
2017-09-04 |
2023-06-07 |
XWPharma Ltd. |
Preparation and use of reactive oxygen species scavenger
|
|
EP3684333B1
(en)
|
2017-09-21 |
2025-03-05 |
Neurocrine Biosciences, Inc. |
High dosage valbenazine formulation and compositions, methods, and kits related thereto
|
|
CN111356461A
(zh)
|
2017-10-04 |
2020-06-30 |
加利福尼亚大学董事会 |
免疫调节性低聚糖
|
|
MY198713A
(en)
|
2017-10-10 |
2023-09-19 |
Neurocrine Biosciences Inc |
Methods for the administration of certain vmat2 inhibitors
|
|
KR20250070134A
(ko)
|
2017-10-10 |
2025-05-20 |
뉴로크린 바이오사이언시즈 인코퍼레이티드 |
특정 vmat2 억제제의 투여 방법
|
|
WO2019099353A1
(en)
|
2017-11-15 |
2019-05-23 |
California State University Northridge |
Compositions and methods for the treatment and prevention of cancer
|
|
JP7254076B2
(ja)
|
2017-11-19 |
2023-04-07 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッド |
置換ヘテロアリール化合物及び使用方法
|
|
WO2019113269A1
(en)
|
2017-12-08 |
2019-06-13 |
Kura Oncology, Inc. |
Methods of treating cancer patients with farnesyltransferase inhibitors
|
|
US20210052529A1
(en)
|
2018-01-10 |
2021-02-25 |
Cura Therapeutics, Llc |
Pharmaceutical compositions comprising dicarboxylic acids and their therapeutic applications
|
|
US11701334B2
(en)
|
2018-01-10 |
2023-07-18 |
Cura Therapeutics, Llc |
Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications
|
|
MX2020007479A
(es)
|
2018-01-10 |
2020-11-24 |
Xwpharma Ltd |
Profármacos de ketamina, composiciones y usos de los mismos.
|
|
BR112020016064A2
(pt)
|
2018-02-08 |
2020-12-08 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Compostos de heteroarila, composições farmacêuticas dos mesmos e seu uso terapêutico
|
|
JP2021518381A
(ja)
|
2018-03-23 |
2021-08-02 |
エイドス セラピューティクス,インコーポレイティド |
Ag10を使用するttrアミロイドーシスの治療方法
|
|
JP7427655B2
(ja)
|
2018-04-27 |
2024-02-05 |
スプルース バイオサイエンシーズ,インク. |
精巣副腎残存腫瘍および卵巣副腎残存腫瘍を処置するための方法
|
|
KR20250115460A
(ko)
|
2018-05-07 |
2025-07-30 |
신닥스 파마슈티컬스, 인크. |
병용 요법을 위한 환자의 선정
|
|
WO2019232724A1
(en)
|
2018-06-06 |
2019-12-12 |
Xw Laboratories, Inc. |
Compounds as nuclear transport modulators and uses thereof
|
|
JOP20200298A1
(ar)
|
2018-06-14 |
2020-11-22 |
Neurocrine Biosciences Inc |
مركبات مثبطة لـ vmat2 وتركيبات وطرق تتعلق بها
|
|
EP3814327A1
(en)
|
2018-06-29 |
2021-05-05 |
Histogen, Inc. |
(s)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating cardiovascular diseases
|
|
WO2020016459A1
(en)
|
2018-07-20 |
2020-01-23 |
Pierre Fabre Medicament |
Receptor for vista
|
|
WO2020019247A1
(en)
|
2018-07-26 |
2020-01-30 |
Xw Laboratories, Inc. |
Compounds as neurokinin-1 receptor antagonists and uses thereof
|
|
EP3829640A4
(en)
|
2018-08-01 |
2022-05-25 |
McMaster University |
Methods for inhibiting microbe growth
|
|
MX2021001017A
(es)
|
2018-08-15 |
2021-04-19 |
Neurocrine Biosciences Inc |
Metodos para la administracion de ciertos inhibidores de transportador vesicular de monoamina de proteinas transportadoras-2 (vmat2).
|
|
TWI834708B
(zh)
|
2018-08-17 |
2024-03-11 |
美商文涵治療有限公司 |
Ag10之調配物
|
|
ES2947089T3
(es)
|
2018-09-30 |
2023-08-01 |
Xwpharma Ltd |
Compuestos como antagonistas del receptor histamínico 3 neuronal y usos de los mismos
|
|
WO2020092720A2
(en)
|
2018-11-01 |
2020-05-07 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
WO2020132071A1
(en)
|
2018-12-19 |
2020-06-25 |
Shy Therapeutics. Llc |
Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and f1brotic disease
|
|
WO2020128033A1
(en)
|
2018-12-20 |
2020-06-25 |
Institut Pasteur |
Cellular metabolism of hiv-1 reservoir seeding in cd4+ t cells
|
|
WO2020132437A1
(en)
|
2018-12-21 |
2020-06-25 |
Kura Oncology, Inc. |
Therapies for squamous cell carcinomas
|
|
EP3921038A1
(en)
|
2019-02-06 |
2021-12-15 |
Dice Alpha, Inc. |
Il-17a modulators and uses thereof
|
|
WO2020180663A1
(en)
|
2019-03-01 |
2020-09-10 |
Kura Oncology, Inc. |
Methods of treating cancer with farnesyltransferase inhibitors
|
|
WO2020181165A1
(en)
|
2019-03-07 |
2020-09-10 |
Conatus Pharmaceuticals Inc. |
Caspase inhibitors and methods of use thereof
|
|
TW202108170A
(zh)
|
2019-03-15 |
2021-03-01 |
美商庫拉腫瘤技術股份有限公司 |
以法呢基轉移酶(farnesyltransferase)抑制劑治療癌症患者之方法
|
|
SG11202110472WA
(en)
|
2019-03-29 |
2021-10-28 |
Kura Oncology Inc |
Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors
|
|
TW202102218A
(zh)
|
2019-04-01 |
2021-01-16 |
美商庫拉腫瘤技術股份有限公司 |
以法呢基(farnesyl)轉移酶抑制劑治療癌症的方法
|
|
MX2021012690A
(es)
|
2019-04-19 |
2022-01-31 |
Ligand Pharm Inc |
Formas cristalinas y metodos para producir formas cristalinas de un compuesto.
|
|
WO2020223583A1
(en)
|
2019-05-02 |
2020-11-05 |
Kura Oncology, Inc. |
Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors
|
|
CA3138403A1
(en)
|
2019-05-20 |
2020-11-26 |
Christopher J. MACNEVIN |
Narrow emission dyes, compositions comprising same, and methods for making and using same
|
|
CN114222802B
(zh)
|
2019-05-20 |
2025-07-11 |
尼尔瓦纳科学股份有限公司 |
窄发射染料、包含其的组合物以及制备和使用其的方法
|
|
BR112021024330A2
(pt)
|
2019-06-03 |
2022-01-11 |
Biotheryx Inc |
Sais cristalinos não higroscópicos de um composto de pirazol, e composições farmacêuticas e uso dos mesmos
|
|
CA3146159A1
(en)
|
2019-07-11 |
2021-01-14 |
Cura Therapeutics, Llc |
Phenyl compounds and pharmaceutical compositions thereof, and their therapeutic applications
|
|
EP3997068A1
(en)
|
2019-07-11 |
2022-05-18 |
Cura Therapeutics, LLC |
Sulfone compounds and pharmaceutical compositions thereof, and their therapeutic applications for the treatment of neurodegenerative diseases
|
|
WO2021021563A1
(en)
|
2019-07-26 |
2021-02-04 |
Espervita Therapeutics, Inc. |
Functionalized long-chain hydrocarbon mono- and di-carboxylic acids useful for the prevention or treatment of disease
|
|
US10940141B1
(en)
|
2019-08-23 |
2021-03-09 |
Neurocrine Biosciences, Inc. |
Methods for the administration of certain VMAT2 inhibitors
|
|
EP4031534A1
(en)
|
2019-09-16 |
2022-07-27 |
Dice Alpha, Inc. |
Il-17a modulators and uses thereof
|
|
US20230008367A1
(en)
|
2019-09-26 |
2023-01-12 |
Abionyx Pharma Sa |
Compounds useful for treating liver diseases
|
|
CA3128410A1
(en)
|
2019-10-11 |
2021-04-15 |
Waterstone Pharmaceuticals (Wuhan) Co., Ltd. |
Ws-635 uses thereof in medicine
|
|
WO2021092240A1
(en)
|
2019-11-05 |
2021-05-14 |
Dermira, Inc. |
Mrgprx2 antagonists for the treatment of inflammatory disorders
|
|
WO2021092264A1
(en)
|
2019-11-05 |
2021-05-14 |
Dermira, Inc. |
MrgprX2 ANTAGONISTS AND USES THEREOF
|
|
CN120698981A
(zh)
|
2019-11-05 |
2025-09-26 |
德米拉公司 |
MrgprX2拮抗剂及其用途
|
|
TW202136238A
(zh)
|
2020-01-06 |
2021-10-01 |
大陸商廣東東陽光藥業有限公司 |
RORγt抑制劑及其製備方法和用途
|
|
TW202136237A
(zh)
|
2020-01-06 |
2021-10-01 |
大陸商廣東東陽光藥業有限公司 |
RORγt抑制劑及其製備方法和用途
|
|
US11529331B2
(en)
|
2020-05-29 |
2022-12-20 |
Boulder Bioscience Llc |
Methods for improved endovascular thrombectomy using 3,3′-diindolylmethane
|
|
WO2021257828A1
(en)
|
2020-06-18 |
2021-12-23 |
Shy Therapeutics, Llc |
Substituted thienopyrimidines that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
|
|
EP4171541A1
(en)
|
2020-06-24 |
2023-05-03 |
NeuroBo Pharmaceuticals, Inc. |
Gemcabene for treatment of cytokine storms and viral-induced inflammation
|
|
US20230312551A1
(en)
|
2020-06-30 |
2023-10-05 |
Sunshine Lake Pharma Co., Ltd. |
Salt of 2-(substituted pyrimidinyl) thiazole carboxamide compound, and composition and use thereof
|
|
EP4149471A4
(en)
|
2020-06-30 |
2024-07-10 |
Prosetta Biosciences, Inc. |
ISOQUINOLINE DERIVATIVES, PROCESSES FOR THE SYNTHESIS AND USES THEREOF
|
|
US20240317681A1
(en)
|
2020-07-07 |
2024-09-26 |
Sunshine Lake Pharma Co., Ltd. |
Pyrrolidine amide derivative salt and use thereof
|
|
US11541009B2
(en)
|
2020-09-10 |
2023-01-03 |
Curemark, Llc |
Methods of prophylaxis of coronavirus infection and treatment of coronaviruses
|
|
WO2022061348A1
(en)
|
2020-09-16 |
2022-03-24 |
Biotheryx, Inc. |
Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
WO2022087335A1
(en)
|
2020-10-23 |
2022-04-28 |
Biotheryx, Inc. |
Kras protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
TW202237580A
(zh)
|
2020-12-14 |
2022-10-01 |
美商拜歐斯瑞克斯公司 |
Pde4降解劑、醫藥組合物及治療應用
|
|
IL303118A
(en)
|
2020-12-16 |
2023-07-01 |
Impact Biomedicines Inc |
Dosing of fedratinib
|
|
US20240124483A1
(en)
|
2021-01-27 |
2024-04-18 |
Shy Therapeutics, Llc |
Methods for the Treatment of Fibrotic Disease
|
|
WO2022165000A1
(en)
|
2021-01-27 |
2022-08-04 |
Shy Therapeutics, Llc |
Methods for the treatment of fibrotic disease
|
|
WO2022189856A1
(en)
|
2021-03-08 |
2022-09-15 |
Abionyx Pharma Sa |
Compounds useful for treating liver diseases
|
|
EP4304716A1
(en)
|
2021-03-10 |
2024-01-17 |
Dice Molecules Sv, Inc. |
Alpha v beta 6 and alpha v beta 1 integrin inhibitors and uses thereof
|
|
EP4326721A1
(en)
|
2021-04-22 |
2024-02-28 |
Protego Biopharma, Inc. |
Spirocyclic imidazolidinones and imidazolidinediones for treatment of light chain amyloidosis
|
|
WO2022251533A1
(en)
|
2021-05-27 |
2022-12-01 |
Protego Biopharma, Inc. |
Heteroaryl diamide ire1/xbp1s activators
|
|
AU2022292649A1
(en)
|
2021-06-16 |
2024-01-04 |
Biotheryx, Inc. |
Sos1 protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
WO2022266249A1
(en)
|
2021-06-16 |
2022-12-22 |
Biotheryx, Inc. |
Kras protein degraders, pharmaceutical compositions thereof, and their therapeutic applications
|
|
US20240358722A1
(en)
|
2021-09-14 |
2024-10-31 |
Impact Biomedicines, Inc. |
Methods of administering fedratinib
|
|
WO2023069770A1
(en)
|
2021-10-22 |
2023-04-27 |
Prosetta Biosciences, Inc. |
Novel host-targeted pan-respiratory antiviral small molecule therapeutics
|
|
WO2023102378A1
(en)
|
2021-11-30 |
2023-06-08 |
Kura Oncology, Inc. |
Macrocyclic compounds having farnesyltransferase inhibitory activity
|
|
US11932665B2
(en)
|
2022-01-03 |
2024-03-19 |
Lilac Therapeutics, Inc. |
Cyclic thiol prodrugs
|
|
WO2023129576A2
(en)
|
2022-01-03 |
2023-07-06 |
Lilac Therapeutics, Inc. |
Acyclic thiol prodrugs
|
|
CN118922189A
(zh)
|
2022-03-02 |
2024-11-08 |
线粒体能量有限公司 |
衍生自烟酸和核糖的新型前药
|
|
GB2619907A
(en)
|
2022-04-01 |
2023-12-27 |
Kanna Health Ltd |
Novel crystalline salt forms of mesembrine
|
|
US12187699B2
(en)
|
2022-04-14 |
2025-01-07 |
Bristol-Myers Squibb Company |
GSPT1 compounds and methods of use of the novel compounds
|
|
CN120092003A
(zh)
|
2022-05-10 |
2025-06-03 |
拜欧斯瑞克斯公司 |
Cdk蛋白降解剂、药物组合物和治疗应用
|
|
KR20250052378A
(ko)
|
2022-07-21 |
2025-04-18 |
안티바 바이오사이언시즈, 인크. |
Hpv 감염 및 hpv-유도 신생물의 치료를 위한 조성물 및 투여 형태
|
|
EP4584259A1
(en)
|
2022-09-09 |
2025-07-16 |
Innovo Therapeutics, Inc. |
Ck1alpha and dual ck1alpha / gspt1 degrading compounds
|
|
EP4593826A1
(en)
|
2022-09-30 |
2025-08-06 |
Boulder Bioscience LLC |
Compositions comprising 3,3'-diindolylmethane for treating non-hemorrhagic closed head injury
|
|
EP4608839A1
(en)
|
2022-10-26 |
2025-09-03 |
Protego Biopharma, Inc. |
Spirocycle containing bicyclic heteroaryl compounds
|
|
US20240174672A1
(en)
|
2022-10-26 |
2024-05-30 |
Protego Biopharma, Inc. |
Spirocycle Containing Pyridone Compounds
|
|
EP4608834A1
(en)
|
2022-10-26 |
2025-09-03 |
Protego Biopharma, Inc. |
Spirocycle containing pyridine compounds
|
|
EP4626865A1
(en)
|
2022-11-30 |
2025-10-08 |
Protego Biopharma, Inc. |
Cyclic pyrazole diamide ire1/xbp1s activators
|
|
WO2024118801A1
(en)
|
2022-11-30 |
2024-06-06 |
Protego Biopharma, Inc. |
Linear heteroaryl diamide ire1/xbp1s activators
|
|
WO2025063888A1
(en)
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|
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|
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|
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|
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|
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|
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|
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