JP7396783B2 - 移植を改善するためのcrispr/cas関連方法および組成物 - Google Patents
移植を改善するためのcrispr/cas関連方法および組成物 Download PDFInfo
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- JP7396783B2 JP7396783B2 JP2017564333A JP2017564333A JP7396783B2 JP 7396783 B2 JP7396783 B2 JP 7396783B2 JP 2017564333 A JP2017564333 A JP 2017564333A JP 2017564333 A JP2017564333 A JP 2017564333A JP 7396783 B2 JP7396783 B2 JP 7396783B2
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021123707A JP2021192607A (ja) | 2015-06-09 | 2021-07-28 | 移植を改善するためのcrispr/cas関連方法および組成物 |
| JP2023095826A JP2023123561A (ja) | 2015-06-09 | 2023-06-09 | 移植を改善するためのcrispr/cas関連方法および組成物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562173321P | 2015-06-09 | 2015-06-09 | |
| US62/173,321 | 2015-06-09 | ||
| US201662294493P | 2016-02-12 | 2016-02-12 | |
| US62/294,493 | 2016-02-12 | ||
| PCT/US2016/036602 WO2016201047A1 (en) | 2015-06-09 | 2016-06-09 | Crispr/cas-related methods and compositions for improving transplantation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021123707A Division JP2021192607A (ja) | 2015-06-09 | 2021-07-28 | 移植を改善するためのcrispr/cas関連方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018523977A JP2018523977A (ja) | 2018-08-30 |
| JP2018523977A5 JP2018523977A5 (https=) | 2019-07-18 |
| JP7396783B2 true JP7396783B2 (ja) | 2023-12-12 |
Family
ID=56236096
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017564333A Active JP7396783B2 (ja) | 2015-06-09 | 2016-06-09 | 移植を改善するためのcrispr/cas関連方法および組成物 |
| JP2021123707A Withdrawn JP2021192607A (ja) | 2015-06-09 | 2021-07-28 | 移植を改善するためのcrispr/cas関連方法および組成物 |
| JP2023095826A Pending JP2023123561A (ja) | 2015-06-09 | 2023-06-09 | 移植を改善するためのcrispr/cas関連方法および組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021123707A Withdrawn JP2021192607A (ja) | 2015-06-09 | 2021-07-28 | 移植を改善するためのcrispr/cas関連方法および組成物 |
| JP2023095826A Pending JP2023123561A (ja) | 2015-06-09 | 2023-06-09 | 移植を改善するためのcrispr/cas関連方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11911415B2 (https=) |
| EP (1) | EP3307887A1 (https=) |
| JP (3) | JP7396783B2 (https=) |
| KR (1) | KR102796744B1 (https=) |
| CN (2) | CN108026526B (https=) |
| AU (2) | AU2016276702B2 (https=) |
| WO (1) | WO2016201047A1 (https=) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10323236B2 (en) | 2011-07-22 | 2019-06-18 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| US20210137991A1 (en) * | 2013-02-08 | 2021-05-13 | Themba Inc. | Gene editing for autoimmune disorders |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| US10077453B2 (en) | 2014-07-30 | 2018-09-18 | President And Fellows Of Harvard College | CAS9 proteins including ligand-dependent inteins |
| CA2986310A1 (en) | 2015-05-11 | 2016-11-17 | Editas Medicine, Inc. | Optimized crispr/cas9 systems and methods for gene editing in stem cells |
| CN108026526B (zh) | 2015-06-09 | 2023-05-12 | 爱迪塔斯医药公司 | 用于改善移植的crispr/cas相关方法和组合物 |
| IL310721B2 (en) | 2015-10-23 | 2025-11-01 | Harvard College | Nucleobase editors and uses thereof |
| CN110214183A (zh) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| WO2018031683A1 (en) | 2016-08-09 | 2018-02-15 | President And Fellows Of Harvard College | Programmable cas9-recombinase fusion proteins and uses thereof |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| KR102622411B1 (ko) | 2016-10-14 | 2024-01-10 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵염기 에디터의 aav 전달 |
| CN110191955B (zh) | 2016-12-13 | 2024-05-31 | 西雅图儿童医院(Dba西雅图儿童研究所) | 在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法 |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| US12390514B2 (en) | 2017-03-09 | 2025-08-19 | President And Fellows Of Harvard College | Cancer vaccine |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| US11542496B2 (en) | 2017-03-10 | 2023-01-03 | President And Fellows Of Harvard College | Cytosine to guanine base editor |
| KR20240116572A (ko) | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| AU2018246377B2 (en) | 2017-03-31 | 2025-01-30 | Cellectis Sa | Universal anti-CD22 chimeric antigen receptor engineered immune cells |
| LT3615674T (lt) | 2017-04-28 | 2024-09-25 | The Regents Of The University Of Colorado, A Body Corporate | Reumatoidinio artrito gydymo būdai, naudojant nukreipiančios rnr hla geno redagavimą genome |
| US11560566B2 (en) | 2017-05-12 | 2023-01-24 | President And Fellows Of Harvard College | Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation |
| CA3068604A1 (en) * | 2017-06-13 | 2018-12-20 | Fate Therapeutics, Inc. | Compositions and methods for inducing myeloid suppressive cells and use thereof |
| MX2019014578A (es) * | 2017-06-21 | 2020-12-01 | Timothy A Bertram | Celulas renales bioactivas inmunoprivilegiadas para el tratamiento de enfermedad renal. |
| CA3067914A1 (en) | 2017-06-30 | 2019-01-03 | Cellectis | Cellular immunotherapy for repetitive administration |
| SG11201913852RA (en) | 2017-07-07 | 2020-01-30 | Toolgen Inc | Target-specific crispr mutant |
| US11866726B2 (en) | 2017-07-14 | 2024-01-09 | Editas Medicine, Inc. | Systems and methods for targeted integration and genome editing and detection thereof using integrated priming sites |
| CN111801345A (zh) | 2017-07-28 | 2020-10-20 | 哈佛大学的校长及成员们 | 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物 |
| WO2019040655A1 (en) * | 2017-08-22 | 2019-02-28 | The Regents Of The University Of California | LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES |
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| WO2016201047A8 (en) | 2017-01-12 |
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| US20240252543A1 (en) | 2024-08-01 |
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| EP3307887A1 (en) | 2018-04-18 |
| CN116334142A (zh) | 2023-06-27 |
| CA2986262A1 (en) | 2016-12-15 |
| HK1255296A1 (zh) | 2019-08-16 |
| WO2016201047A1 (en) | 2016-12-15 |
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