BR112019006388A2 - enzimas modificadoras de ácido nucleico guiadas por rna e métodos de uso das mesmas - Google Patents

enzimas modificadoras de ácido nucleico guiadas por rna e métodos de uso das mesmas

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Publication number
BR112019006388A2
BR112019006388A2 BR112019006388A BR112019006388A BR112019006388A2 BR 112019006388 A2 BR112019006388 A2 BR 112019006388A2 BR 112019006388 A BR112019006388 A BR 112019006388A BR 112019006388 A BR112019006388 A BR 112019006388A BR 112019006388 A2 BR112019006388 A2 BR 112019006388A2
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Brazil
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casy
rna
proteins
nucleic acids
acids encoding
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BR112019006388A
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English (en)
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Burstein David
A Doudna Jennifer
F Banfield Jillian
Benjamin Harrington Lucas
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Univ California
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Publication of BR112019006388A2 publication Critical patent/BR112019006388A2/pt

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Abstract

a presente divulgação fornece proteínas casy, ácidos nucleicos que codificam as proteínas casy e células hospedeiras modificadas que compreendem as proteínas casy e/ou os ácidos nucleicos que as codificam. as proteínas casy são úteis em uma variedade de aplicações, que são fornecidas. a presente divulgação fornece rnas guia de casy que se ligam e fornecem especificidade de sequência às proteínas casy, ácidos nucleicos que codificam os rnas guia de casy e células hospedeiras modificadas que compreendem os rnas guia de casy e/ou ácidos nucleicos que as codificam. os rnas guia de casy são úteis em uma variedade de aplicações, que são fornecidas. a presente divulgação fornece métodos de identificação de uma endonuclease guiada por rna crispr.
BR112019006388A 2016-09-30 2017-09-28 enzimas modificadoras de ácido nucleico guiadas por rna e métodos de uso das mesmas BR112019006388A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662402849P 2016-09-30 2016-09-30
PCT/US2017/054047 WO2018064352A1 (en) 2016-09-30 2017-09-28 Rna-guided nucleic acid modifying enzymes and methods of use thereof

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BR112019006388A2 true BR112019006388A2 (pt) 2019-06-25

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US (2) US11371062B2 (pt)
EP (1) EP3532089A4 (pt)
JP (2) JP7306696B2 (pt)
KR (2) KR20190072548A (pt)
CN (1) CN110418647A (pt)
AU (1) AU2017335883B2 (pt)
BR (1) BR112019006388A2 (pt)
CA (1) CA3038982A1 (pt)
EA (1) EA201990860A1 (pt)
GB (1) GB2569734B (pt)
IL (1) IL265599A (pt)
MX (1) MX2019003678A (pt)
SA (1) SA519401442B1 (pt)
WO (1) WO2018064352A1 (pt)

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