MX2019003678A - Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas. - Google Patents

Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas.

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Publication number
MX2019003678A
MX2019003678A MX2019003678A MX2019003678A MX2019003678A MX 2019003678 A MX2019003678 A MX 2019003678A MX 2019003678 A MX2019003678 A MX 2019003678A MX 2019003678 A MX2019003678 A MX 2019003678A MX 2019003678 A MX2019003678 A MX 2019003678A
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MX
Mexico
Prior art keywords
casy
proteins
nucleic acids
acids encoding
rna
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MX2019003678A
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English (en)
Inventor
Jennifer A Doudna
Jillian F Banfield
David Burstein
Lucas Benjamin Harrington
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Univ California
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Publication date
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Publication of MX2019003678A publication Critical patent/MX2019003678A/es

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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C07K2319/00—Fusion polypeptide
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

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Abstract

La presente descripción proporciona proteínas CasY, ácidos nucleicos que codifican las proteínas CasY y células hospedadoras modificadas que comprenden las proteínas CasY y/o ácidos nucleicos que las codifican. Las proteínas CasY son útiles en una variedad de aplicaciones que se proporcionan. La presente descripción proporciona ARN guías de CasY que se unen a y proporcionan especificidad de secuencia a las proteínas CasY, ácidos nucleicos que codifican los ARN guías de CasY y células hospedadoras modificadas que comprenden los ARN guías de CasY y/o ácidos nucleicos que los codifican. Los ARN guías de CasY son útiles en una variedad de aplicaciones que se proporcionan. La presente descripción proporciona métodos para identificar una endonucleasa guiada por ARN de CRISPR.
MX2019003678A 2016-09-30 2017-09-28 Enzimas modificadoras de ácido nucleico guiadas por arn y métodos de uso de estas. MX2019003678A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662402849P 2016-09-30 2016-09-30
PCT/US2017/054047 WO2018064352A1 (en) 2016-09-30 2017-09-28 Rna-guided nucleic acid modifying enzymes and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2019003678A true MX2019003678A (es) 2020-08-13

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US (2) US11371062B2 (es)
EP (1) EP3532089A4 (es)
JP (2) JP7306696B2 (es)
KR (2) KR20230169449A (es)
CN (1) CN110418647A (es)
AU (1) AU2017335883B2 (es)
BR (1) BR112019006388A2 (es)
CA (1) CA3038982A1 (es)
EA (1) EA201990860A1 (es)
GB (1) GB2569734B (es)
IL (1) IL265599A (es)
MX (1) MX2019003678A (es)
WO (1) WO2018064352A1 (es)

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GB2569734B (en) 2022-09-07
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