JP6952683B2 - 身体試料中の実体を検出する方法および装置 - Google Patents

身体試料中の実体を検出する方法および装置 Download PDF

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JP6952683B2
JP6952683B2 JP2018512961A JP2018512961A JP6952683B2 JP 6952683 B2 JP6952683 B2 JP 6952683B2 JP 2018512961 A JP2018512961 A JP 2018512961A JP 2018512961 A JP2018512961 A JP 2018512961A JP 6952683 B2 JP6952683 B2 JP 6952683B2
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body sample
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JP2018534605A (ja
JP2018534605A5 (enExample
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シュロモ エシェル，ヨチャイ
シュロモ エシェル，ヨチャイ
レズミー，ナタリー
グルック，ダン
ヤフィン，アルノン フーリー
ヤフィン，アルノン フーリー
ヨエル ポラック，ジョセフ
ヨエル ポラック，ジョセフ
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エス．ディー．サイト ダイアグノスティクス リミテッド
エス．ディー．サイト ダイアグノスティクス リミテッド
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/8851—Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
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    • G02B21/365—Control or image processing arrangements for digital or video microscopes
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
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    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
    • G06F18/214—Generating training patterns; Bootstrap methods, e.g. bagging or boosting
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/88—Investigating the presence of flaws or contamination
    • G01N21/8851—Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges
    • G01N2021/8887—Scan or image signal processing specially adapted therefor, e.g. for scan signal adjustment, for detecting different kinds of defects, for compensating for structures, markings, edges based on image processing techniques
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30101—Blood vessel; Artery; Vein; Vascular
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
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  • General Physics & Mathematics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Pathology (AREA)
  • Immunology (AREA)
  • Signal Processing (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Radiology & Medical Imaging (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Evolutionary Computation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Microscoopes, Condenser (AREA)
  • Image Processing (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Image Analysis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
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PCT/IL2016/051025 WO2017046799A1 (en) 2015-09-17 2016-09-15 Methods and apparatus for detecting an entity in a bodily sample

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12189112B2 (en) 2019-12-12 2025-01-07 S.D. Sight Diagnostics Ltd. Artificial generation of color blood smear image
US12196940B2 (en) 2017-11-14 2025-01-14 S.D. Sight Diagnostics Ltd. Sample carrier for microscopy and optical density measurements
US12196664B2 (en) 2016-03-30 2025-01-14 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
US12393010B2 (en) 2013-08-26 2025-08-19 S.D. Sight Diagnostics Ltd. Distinguishing between entities in a blood sample
US12436101B2 (en) 2019-12-12 2025-10-07 S.D. Sight Diagnostics Ltd. Microscopy unit
US12498325B2 (en) 2019-10-22 2025-12-16 S.D. Sight Diagnostics Ltd. Accounting for errors in optical measurements
US12523579B2 (en) 2019-12-12 2026-01-13 S.D. Sight Diagnostics Ltd. Detecting platelets in a blood sample
US12711788B2 (en) 2020-12-10 2026-08-18 S.D. Sight Diagnostics Ltd. Classification models for analyzing a sample

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
CN104169719B (zh) 2011-12-29 2017-03-08 思迪赛特诊断有限公司 用于检测生物样品中病原体的方法和系统
EP3869257B1 (en) 2013-05-23 2024-05-08 S.D. Sight Diagnostics Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for preparing a monolayer of cells, particularly suitable for diagnosis
CN107077732B (zh) 2014-08-27 2020-11-24 思迪赛特诊断有限公司 用于对数字显微镜计算聚焦变化的系统及方法
US10625259B1 (en) 2014-11-26 2020-04-21 Medica Corporation Automated microscopic cell analysis
US12005441B1 (en) 2014-11-26 2024-06-11 Medica Corporation Automated microscopic cell analysis
EP3859425B1 (en) 2015-09-17 2024-04-17 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
US11307196B2 (en) 2016-05-11 2022-04-19 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
AU2017263807B2 (en) 2016-05-11 2023-02-02 S.D. Sight Diagnostics Ltd Performing optical measurements on a sample
US11450121B2 (en) * 2017-06-27 2022-09-20 The Regents Of The University Of California Label-free digital brightfield analysis of nucleic acid amplification
CN110892247B (zh) 2017-08-17 2023-08-25 雅培医护站股份有限公司 用于执行光学和电化学测定的设备、系统和方法
CN110869745B (zh) 2017-08-17 2023-08-11 雅培医护站股份有限公司 用于执行光学测定的设备、系统和方法
WO2019035082A1 (en) 2017-08-17 2019-02-21 Abbott Point Of Care Inc. TECHNIQUES FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS WITH UNIVERSAL CIRCUITS
US11047845B1 (en) 2017-11-15 2021-06-29 Medica Corporation Control material and methods for cell analyzers
US12026900B2 (en) 2017-12-27 2024-07-02 Cllag GmbH International Hyperspectral imaging in a light deficient environment
US11592657B2 (en) 2018-12-18 2023-02-28 Hemotech Cognition, LLC Method and system for identifying objects in a blood sample
JP6898955B2 (ja) * 2019-01-29 2021-07-07 ケーディーアイコンズ株式会社 情報処理装置
US12039796B2 (en) * 2019-02-01 2024-07-16 Sartorius Bioanalytical Instruments, Inc. Method for classifying cells
US11187658B2 (en) 2019-06-20 2021-11-30 Cilag Gmbh International Fluorescence imaging with fixed pattern noise cancellation
US11925328B2 (en) 2019-06-20 2024-03-12 Cilag Gmbh International Noise aware edge enhancement in a pulsed hyperspectral imaging system
US12013496B2 (en) 2019-06-20 2024-06-18 Cilag Gmbh International Noise aware edge enhancement in a pulsed laser mapping imaging system
US11758256B2 (en) 2019-06-20 2023-09-12 Cilag Gmbh International Fluorescence imaging in a light deficient environment
US11398011B2 (en) 2019-06-20 2022-07-26 Cilag Gmbh International Super resolution and color motion artifact correction in a pulsed laser mapping imaging system
US11700995B2 (en) 2019-06-20 2023-07-18 Cilag Gmbh International Speckle removal in a pulsed fluorescence imaging system
US10952619B2 (en) 2019-06-20 2021-03-23 Ethicon Llc Hyperspectral and fluorescence imaging and topology laser mapping with minimal area monolithic image sensor
US11793399B2 (en) 2019-06-20 2023-10-24 Cilag Gmbh International Super resolution and color motion artifact correction in a pulsed hyperspectral imaging system
US11898909B2 (en) 2019-06-20 2024-02-13 Cilag Gmbh International Noise aware edge enhancement in a pulsed fluorescence imaging system
US11432706B2 (en) 2019-06-20 2022-09-06 Cilag Gmbh International Hyperspectral imaging with minimal area monolithic image sensor
US12126887B2 (en) 2019-06-20 2024-10-22 Cilag Gmbh International Hyperspectral and fluorescence imaging with topology laser scanning in a light deficient environment
US11624830B2 (en) 2019-06-20 2023-04-11 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for laser mapping imaging
US11716543B2 (en) 2019-06-20 2023-08-01 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for fluorescence imaging
US11134832B2 (en) 2019-06-20 2021-10-05 Cilag Gmbh International Image rotation in an endoscopic hyperspectral, fluorescence, and laser mapping imaging system
US11389066B2 (en) 2019-06-20 2022-07-19 Cilag Gmbh International Noise aware edge enhancement in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11937784B2 (en) 2019-06-20 2024-03-26 Cilag Gmbh International Fluorescence imaging in a light deficient environment
US11944273B2 (en) 2019-06-20 2024-04-02 Cilag Gmbh International Fluorescence videostroboscopy of vocal cords
US11671691B2 (en) 2019-06-20 2023-06-06 Cilag Gmbh International Image rotation in an endoscopic laser mapping imaging system
US11931009B2 (en) 2019-06-20 2024-03-19 Cilag Gmbh International Offset illumination of a scene using multiple emitters in a hyperspectral imaging system
US11516387B2 (en) 2019-06-20 2022-11-29 Cilag Gmbh International Image synchronization without input clock and data transmission clock in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11903563B2 (en) 2019-06-20 2024-02-20 Cilag Gmbh International Offset illumination of a scene using multiple emitters in a fluorescence imaging system
US11012599B2 (en) 2019-06-20 2021-05-18 Ethicon Llc Hyperspectral imaging in a light deficient environment
US11674848B2 (en) 2019-06-20 2023-06-13 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for hyperspectral imaging
US12440085B2 (en) 2019-06-20 2025-10-14 Cilag Gmbh International Image synchronization without input clock and data transmission clock in a pulsed laser mapping imaging system
US10841504B1 (en) 2019-06-20 2020-11-17 Ethicon Llc Fluorescence imaging with minimal area monolithic image sensor
US11141052B2 (en) 2019-06-20 2021-10-12 Cilag Gmbh International Image rotation in an endoscopic fluorescence imaging system
US11633089B2 (en) 2019-06-20 2023-04-25 Cilag Gmbh International Fluorescence imaging with minimal area monolithic image sensor
US20200397245A1 (en) 2019-06-20 2020-12-24 Ethicon Llc Minimizing image sensor input/output in a pulsed fluorescence imaging system
US11213194B2 (en) 2019-06-20 2022-01-04 Cilag Gmbh International Optical fiber waveguide in an endoscopic system for hyperspectral, fluorescence, and laser mapping imaging
US11471055B2 (en) 2019-06-20 2022-10-18 Cilag Gmbh International Noise aware edge enhancement in a pulsed fluorescence imaging system
US11412920B2 (en) 2019-06-20 2022-08-16 Cilag Gmbh International Speckle removal in a pulsed fluorescence imaging system
US11337596B2 (en) 2019-06-20 2022-05-24 Cilag Gmbh International Controlling integral energy of a laser pulse in a fluorescence imaging system
US11533417B2 (en) 2019-06-20 2022-12-20 Cilag Gmbh International Laser scanning and tool tracking imaging in a light deficient environment
US11412152B2 (en) 2019-06-20 2022-08-09 Cilag Gmbh International Speckle removal in a pulsed hyperspectral imaging system
US11516388B2 (en) 2019-06-20 2022-11-29 Cilag Gmbh International Pulsed illumination in a fluorescence imaging system
US20200397239A1 (en) 2019-06-20 2020-12-24 Ethicon Llc Offset illumination of a scene using multiple emitters in a fluorescence imaging system
US12007550B2 (en) 2019-06-20 2024-06-11 Cilag Gmbh International Driving light emissions according to a jitter specification in a spectral imaging system
US11360028B2 (en) 2019-06-20 2022-06-14 Cilag Gmbh International Super resolution and color motion artifact correction in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11540696B2 (en) 2019-06-20 2023-01-03 Cilag Gmbh International Noise aware edge enhancement in a pulsed fluorescence imaging system
US11457154B2 (en) 2019-06-20 2022-09-27 Cilag Gmbh International Speckle removal in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US11622094B2 (en) 2019-06-20 2023-04-04 Cilag Gmbh International Wide dynamic range using a monochrome image sensor for fluorescence imaging
US11237270B2 (en) 2019-06-20 2022-02-01 Cilag Gmbh International Hyperspectral, fluorescence, and laser mapping imaging with fixed pattern noise cancellation
US11550057B2 (en) 2019-06-20 2023-01-10 Cilag Gmbh International Offset illumination of a scene using multiple emitters in a fluorescence imaging system
WO2021081424A1 (en) 2019-10-25 2021-04-29 University Of Utah Research Foundation Micro-balance biosensors to detect whole viruses
EP3817005A1 (en) * 2019-11-01 2021-05-05 Koninklijke Philips N.V. System for infection diagnosis
EP3826024A1 (en) * 2019-11-19 2021-05-26 Koninklijke Philips N.V. Apparatus for diagnostic image acquisition determination
MX2022007125A (es) 2019-12-12 2022-07-11 S D Sight Diagnostics Ltd Modelos de clasificacion para analizar una muestra.
EP4073491A1 (en) * 2019-12-12 2022-10-19 S.D. Sight Diagnostics Ltd. Off-focus microscopic images of a sample
CN112469984B (zh) * 2019-12-31 2024-04-09 深圳迈瑞生物医疗电子股份有限公司 一种图像分析装置及其成像方法
CN111272659A (zh) * 2020-03-10 2020-06-12 华东师范大学 一种全自动结核杆菌显微扫描分析仪
JP7649506B2 (ja) 2020-03-30 2025-03-21 学校法人順天堂 疾患鑑別支援方法、疾患鑑別支援装置、及び疾患鑑別支援コンピュータプログラム
GB202006144D0 (en) * 2020-04-27 2020-06-10 Univ Oxford Innovation Ltd Method of diagnosing a biological entity, and diagnostic device
JP7506524B2 (ja) * 2020-05-20 2024-06-26 株式会社エビデント 顕微鏡システム、制御方法、プログラム
WO2022009104A2 (en) 2020-07-07 2022-01-13 S.D. Sight Diagnostics Ltd Focusing a microscope using fluorescent images
CN113933134B (zh) * 2020-07-14 2026-06-12 深圳迈瑞生物医疗电子股份有限公司 一种用于样本染色的染色方法以及相关设备
US11599984B2 (en) 2021-04-29 2023-03-07 Syscom, Inc. Methods and apparatus for detecting defects for poultry piece grading
EP4469204A1 (en) 2022-01-25 2024-12-04 S.D. Sight Diagnostics Ltd. Sample carrier for use with a bodily sample
GB202218615D0 (en) 2022-12-12 2023-01-25 S D Sight Diagnostics Ltd System and method for analyzing bodily samples
US20240337627A1 (en) * 2023-04-07 2024-10-10 Onto Innovation Inc. System and method for fast microscopy
JP2026520403A (ja) 2023-05-18 2026-06-23 エス．ディー．サイト ダイアグノスティックス リミテッド 生体サンプルの顕微鏡分析のための装置及び方法
US12693514B2 (en) 2023-11-08 2026-07-28 Idexx Laboratories, Inc. Methods and systems for verifying biological analysis devices

Family Cites Families (403)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3203768A (en) 1961-08-01 1965-08-31 Westinghouse Electric Corp Apparatus of zone refining and controlling solute segregation in solidifying melts by electromagnetic means
US3603156A (en) 1970-02-04 1971-09-07 Gradko Glass Lab Inc Disposable dilution system
US3676076A (en) 1970-09-24 1972-07-11 Gradko Glass Lab Inc Disposable container
GB1324323A (en) 1971-02-05 1973-07-25 Image Analysing Computers Ltd Automatic focusing of an optical image
US3967056A (en) 1973-02-26 1976-06-29 Minolta Camera Kabushiki Kaisha Automatic focusing apparatus
US3916205A (en) 1973-05-31 1975-10-28 Block Engineering Differential counting of leukocytes and other cells
JPS5916667B2 (ja) 1975-02-28 1984-04-17 トウアイヨウデンシ カブシキガイシヤ 自動血液分析装置
US4076419A (en) 1976-07-12 1978-02-28 Kleker Richard G Method and apparatus for hematology
US4097845A (en) * 1976-11-01 1978-06-27 Rush-Presbyterian-St. Luke's Medical Center Method of and an apparatus for automatic classification of red blood cells
US4209548A (en) 1976-11-01 1980-06-24 Rush-Presbyterian-St. Luke's Medical Center Method for the preparation of blood samples for automated analysis
US4199748A (en) 1976-11-01 1980-04-22 Rush-Presbyterian-St. Luke's Medical Center Automated method and apparatus for classification of cells with application to the diagnosis of anemia
DE2910875C2 (de) 1979-03-20 1985-11-14 Kernforschungszentrum Karlsruhe Gmbh, 7500 Karlsruhe Verfahren zur automatischen Scharfeinstellung
US4453266A (en) 1980-04-21 1984-06-05 Rush-Presbyterian-St. Luke's Medical Center Method and apparatus for measuring mean cell volume of red blood cells
ES8307122A1 (es) 1981-08-27 1983-06-16 Becton Dickinson Co "perfeccionamientos introducidos en un aparato para introducir reactivos en recipientes de recogida de muestras".
US4454235A (en) 1982-06-01 1984-06-12 Miles Laboratories, Inc. Capillary tube holder for liquid transfer in immunoassay
US4494479A (en) 1982-10-14 1985-01-22 Coulter Electronics, Inc. Slide preparation apparatus
JPS60501339A (ja) 1983-01-10 1985-08-22 ジエン−プロ−ブ　インコ−ポレィテッド 生物を検出、同定又は定量する方法およびキット
US4580895A (en) 1983-10-28 1986-04-08 Dynatech Laboratories, Incorporated Sample-scanning photometer
JPS60162955A (ja) * 1984-02-03 1985-08-24 Hitachi Ltd 血球自動分析装置
DE3574408D1 (en) 1984-05-15 1989-12-28 Lawrence Kass Single dye replacement for romanowsky plural dye variable compositions in human biopsy specimen constituent identifications
US4700298A (en) 1984-09-14 1987-10-13 Branko Palcic Dynamic microscope image processing scanner
JPS61198204A (ja) 1985-02-28 1986-09-02 Disco Abrasive Sys Ltd 顕微鏡のオ−トフオ−カス方法
US5164598A (en) 1985-08-05 1992-11-17 Biotrack Capillary flow device
US4761381A (en) 1985-09-18 1988-08-02 Miles Inc. Volume metering capillary gap device for applying a liquid sample onto a reactive surface
DE3707487A1 (de) 1986-05-16 1987-11-26 Reichert Optische Werke Ag Verfahren zur autofokussierung von mikroskopen und mikroskope mit einer autofokussierung
JPH0774856B2 (ja) 1986-10-16 1995-08-09 オリンパス光学工業株式会社 自動焦点調節方法
US4774192A (en) 1987-01-28 1988-09-27 Technimed Corporation A dry reagent delivery system with membrane having porosity gradient
US4849340A (en) 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US4849430A (en) 1988-03-09 1989-07-18 Monsanto Company Method of inhibiting virus
US6262798B1 (en) 1992-09-29 2001-07-17 Board Of Regents, The University Of Texas System Method and apparatus for direct spectrophotometric measurements in unaltered whole blood
US5001067A (en) 1989-09-18 1991-03-19 Nova Biomedical Corporation Determining the concentration of water soluble species in biological fluid
US5064282A (en) 1989-09-26 1991-11-12 Artel, Inc. Photometric apparatus and method for measuring hemoglobin
US5229265A (en) 1990-03-13 1993-07-20 Litron Laboratories Process for analyzing clastogenic agents
EP0479231B1 (en) 1990-10-01 1996-03-27 Canon Kabushiki Kaisha Apparatus and method for measuring specimen
JP2927979B2 (ja) * 1991-02-22 1999-07-28 シスメックス株式会社 フローサイトメトリーによる赤芽球の分類方法
BR9305952A (pt) * 1992-02-24 1997-10-21 Coulter Corp Produto de controle de hematologia processo para utilizar o mesmo e processo para fabricação de análogos de leucócito
US5331958A (en) 1992-03-31 1994-07-26 University Of Manitoba Spectrophotometric blood analysis
US5430542A (en) 1992-04-10 1995-07-04 Avox Systems, Inc. Disposable optical cuvette
US5342790A (en) 1992-10-30 1994-08-30 Becton Dickinson And Company Apparatus for indirect fluorescent assay of blood samples
DE69424079T2 (de) 1993-02-22 2000-09-07 Sysmex Corp., Kobe Ein Reagenz zum Nachweis von malariainfizierten Zellen und ein Nachweis-Verfahren für malariainfizierte Zellen unter Verwendung desselben
US5483055A (en) 1994-01-18 1996-01-09 Thompson; Timothy V. Method and apparatus for performing an automatic focus operation for a microscope
JP5161052B2 (ja) 2008-12-04 2013-03-13 オリンパス株式会社 顕微鏡システム、標本観察方法およびプログラム
US6074789A (en) 1994-03-08 2000-06-13 Philips Electronics N.A. Corp. Method for producing phosphor screens, and color cathode ray tubes incorporating same
US5590660A (en) 1994-03-28 1997-01-07 Xillix Technologies Corp. Apparatus and method for imaging diseased tissue using integrated autofluorescence
US5782770A (en) 1994-05-12 1998-07-21 Science Applications International Corporation Hyperspectral imaging methods and apparatus for non-invasive diagnosis of tissue for cancer
JPH07325247A (ja) 1994-05-31 1995-12-12 Nikon Corp 自動合焦装置
DK0769159T3 (da) 1994-07-01 1999-09-27 Jeffrey H Price Autofokuseringssystem til scanningmikroskopi
US5932872A (en) 1994-07-01 1999-08-03 Jeffrey H. Price Autofocus system for scanning microscopy having a volume image formation
US5566249A (en) * 1994-09-20 1996-10-15 Neopath, Inc. Apparatus for detecting bubbles in coverslip adhesive
US5978497A (en) 1994-09-20 1999-11-02 Neopath, Inc. Apparatus for the identification of free-lying cells
WO1996012981A1 (en) 1994-10-21 1996-05-02 Kla Instruments Corporation Autofocusing apparatus and method for high resolution microscope system
AU4131796A (en) 1994-10-27 1996-05-23 Entremed, Inc Identification of infection with flow cytometry
EP0713087B1 (en) 1994-11-17 1999-04-14 Chemunex Apparatus and process for rapid and ultrasensitive detection and counting of microorganisms by fluorescence
SE504193C2 (sv) 1995-04-21 1996-12-02 Hemocue Ab Kapillär mikrokyvett
JPH08313340A (ja) 1995-05-23 1996-11-29 Eresu Trading Kk 紫外線測定シート及び紫外線測定機能付き日焼け装置
US5625706A (en) * 1995-05-31 1997-04-29 Neopath, Inc. Method and apparatus for continously monitoring and forecasting slide and specimen preparation for a biological specimen population
US5671288A (en) * 1995-05-31 1997-09-23 Neopath, Inc. Method and apparatus for assessing slide and specimen preparation quality
US5985595A (en) 1995-06-07 1999-11-16 The University Of Connecticut Early detection of Borrelia infection
JP3640712B2 (ja) 1995-08-11 2005-04-20 衛 石澤 血小板検査方法及び血小板検査用採血管
US5670240A (en) 1995-11-09 1997-09-23 Flex Products, Inc. Embossed substrate and photoreceptor device incorporating the same and method
US6005964A (en) 1996-01-24 1999-12-21 The Board Of Trustees Of The University Of Illinois Automatic machine vision microscope slide inspection system and method
KR0165522B1 (ko) 1996-05-23 1999-03-20 김광호 혈증성분 무혈진단을 위한 최적지점 검색장치및 이를 이용한 무혈진단기
GB9620934D0 (en) 1996-10-08 1996-11-27 Molecular Drives Limited Multi-well containers
WO1998050777A1 (en) 1997-05-05 1998-11-12 Chemometec A/S A method and a system for determination of particles in a liquid sample
US6074879A (en) 1997-06-23 2000-06-13 Bayer Corporation Synthetic polymer particles for use as standards and calibrators in flow cytometry
JPH1173903A (ja) 1997-08-28 1999-03-16 Jeol Ltd 走査電子顕微鏡のオートフォーカス方法
GB2329014A (en) 1997-09-05 1999-03-10 Colin Campbell Automated identification of tubercle bacilli
US6064474A (en) 1998-02-06 2000-05-16 Optical Sensors, Inc. Optical measurement of blood hematocrit incorporating a self-calibration algorithm
US20020028471A1 (en) 1998-02-20 2002-03-07 Oberhardt Bruce J. Cell analysis methods and apparatus
US6723290B1 (en) 1998-03-07 2004-04-20 Levine Robert A Container for holding biologic fluid for analysis
US5948686A (en) 1998-03-07 1999-09-07 Robert A. Leuine Method for performing blood cell counts
US6929953B1 (en) 1998-03-07 2005-08-16 Robert A. Levine Apparatus for analyzing biologic fluids
US6235536B1 (en) 1998-03-07 2001-05-22 Robert A. Levine Analysis of quiescent anticoagulated whole blood samples
US6350613B1 (en) 1998-03-07 2002-02-26 Belton Dickinson & Co. Determination of white blood cell differential and reticulocyte counts
US6027695A (en) 1998-04-01 2000-02-22 Dupont Pharmaceuticals Company Apparatus for holding small volumes of liquids
KR20010083041A (ko) 1998-06-02 2001-08-31 추후 파수 도메인 반사측정과 배경 진폭 감소 및 보상을 사용한공초점 간섭 마이크로스코피용 방법 및 장치
US6101104A (en) 1998-06-04 2000-08-08 Hughes Electronics Corporation Predictive threshold synchronous rectifier control
IT1304854B1 (it) 1998-07-29 2001-04-05 Paolo Fazii Metodo di differenziazione cromatica dei microrganismi in fluorescenza
US6132685A (en) 1998-08-10 2000-10-17 Caliper Technologies Corporation High throughput microfluidic systems and methods
US6320979B1 (en) 1998-10-06 2001-11-20 Canon Kabushiki Kaisha Depth of field enhancement
US6496260B1 (en) 1998-12-23 2002-12-17 Molecular Devices Corp. Vertical-beam photometer for determination of light absorption pathlength
JP2000199845A (ja) 1999-01-05 2000-07-18 Ricoh Co Ltd 自動合焦装置及び自動合焦方法
US6330348B1 (en) * 1999-01-21 2001-12-11 Resolution Sciences Corporation Method and apparatus for measurement of microtome performance
US8406498B2 (en) 1999-01-25 2013-03-26 Amnis Corporation Blood and cell analysis using an imaging flow cytometer
US6344340B1 (en) 1999-03-01 2002-02-05 Novus International, Inc. Viability assay for sporocyst-forming protozoa
US6582964B1 (en) 1999-05-12 2003-06-24 Cme Telemetrix Inc. Method and apparatus for rapid measurement of HbA1c
US7034883B1 (en) 1999-08-10 2006-04-25 Cellavision Ab Automatic focusing
US6949384B2 (en) 2001-12-21 2005-09-27 Spectromedical Inc. Method for monitoring degradation of Hb-based blood substitutes
US6611777B2 (en) 1999-11-23 2003-08-26 James Samsoondar Method for calibrating spectrophotometric apparatus
US6711516B2 (en) 1999-11-23 2004-03-23 Spectromedical Inc. Method for calibrating spectrophotometric apparatus
ATE386815T1 (de) 2000-01-06 2008-03-15 Caliper Life Sciences Inc Methoden und syteme zur überwachung intrazellulärer bindereaktionen
JP3516918B2 (ja) 2000-01-19 2004-04-05 株式会社日立国際電気 半導体装置の製造方法及び半導体製造装置
US6836559B2 (en) 2000-03-09 2004-12-28 The Regents Of The University Of California Automated video-microscopic imaging and data acquisition system for colloid deposition measurements
WO2001078005A2 (en) 2000-04-11 2001-10-18 Cornell Research Foundation, Inc. System and method for three-dimensional image rendering and analysis
US7668362B2 (en) 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US6799119B1 (en) 2000-05-15 2004-09-28 Colorado School Of Mines Method for detection of biological related materials using biomarkers
US6554788B1 (en) 2000-06-02 2003-04-29 Cobe Cardiovascular, Inc. Hematocrit sampling system
US7630063B2 (en) 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
WO2001092859A1 (en) 2000-06-02 2001-12-06 Medicometrics Aps Method and system for classifying a biological sample
US6632681B1 (en) 2000-07-24 2003-10-14 Ey Laboratories Reagent delivery device and method of use
US6819408B1 (en) 2000-09-27 2004-11-16 Becton, Dickinson And Company Method for obtaining a monolayer of desired particles in a liquid sample
US6448024B1 (en) 2000-10-03 2002-09-10 Roche Diagnostics Corporation Method, reagent, cartridge, and device for determining fibrinogen
US20100261159A1 (en) 2000-10-10 2010-10-14 Robert Hess Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
AU2002212914A1 (en) 2000-11-07 2002-05-21 Cellavision Ab Autofocusing
US7027628B1 (en) 2000-11-14 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Automated microscopic image acquisition, compositing, and display
US7155049B2 (en) 2001-01-11 2006-12-26 Trestle Acquisition Corp. System for creating microscopic digital montage images
CA2434283A1 (en) 2001-01-12 2002-07-25 General Hospital Corporation System and method for enabling simultaneous calibration and imaging of a medium
DK1366289T3 (da) 2001-01-30 2007-08-13 Outland Technologies Inc Fortrængningsapparat, fremgnagsmåde og apparat til frembringelse af en minimal kontakttætning
JP4937457B2 (ja) 2001-03-01 2012-05-23 オリンパス株式会社 顕微鏡制御装置、顕微鏡制御システム、顕微鏡の制御方法、プログラム、及び記録媒体
US6898451B2 (en) 2001-03-21 2005-05-24 Minformed, L.L.C. Non-invasive blood analyte measuring system and method utilizing optical absorption
US6519355B2 (en) 2001-03-28 2003-02-11 Alan C. Nelson Optical projection imaging system and method for automatically detecting cells having nuclear and cytoplasmic densitometric features associated with disease
EP1381229B1 (en) 2001-03-30 2008-12-10 National Institute of Advanced Industrial Science and Technology Real-time omnifocus microscope camera
US6884983B2 (en) 2002-06-10 2005-04-26 Palantyr Research, Llc Imaging system for examining biological material
US7105795B2 (en) 2001-07-06 2006-09-12 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
US7132636B1 (en) 2001-07-06 2006-11-07 Palantyr Research, Llc Imaging system and methodology employing reciprocal space optical design
US7151246B2 (en) 2001-07-06 2006-12-19 Palantyr Research, Llc Imaging system and methodology
US7288751B2 (en) 2001-07-06 2007-10-30 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
US7863552B2 (en) 2001-07-06 2011-01-04 Palantyr Research Llc Digital images and related methodologies
US7248716B2 (en) 2001-07-06 2007-07-24 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
US7385168B2 (en) 2001-07-06 2008-06-10 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design
US6664528B1 (en) 2001-07-06 2003-12-16 Palantyr Research, Llc Imaging system and methodology employing reciprocal space optical design
US7439478B2 (en) 2001-07-06 2008-10-21 Palantyr Research, Llc Imaging system, methodology, and applications employing reciprocal space optical design having at least one pixel being scaled to about a size of a diffraction-limited spot defined by a microscopic optical system
US6872930B2 (en) 2003-03-31 2005-03-29 Palantyr Research, Llc Imaging system and methodology employing reciprocal space optical design
US7338168B2 (en) 2001-07-06 2008-03-04 Palantyr Research, Llc Particle analyzing system and methodology
JP4751535B2 (ja) 2001-07-26 2011-08-17 シスメックス株式会社 分画方法とそれを用いた血液分析装置
ATE437216T1 (de) 2001-09-06 2009-08-15 Genomic Profiling Systems Inc Schnellnachweis replizierender zellen
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
SE0104443D0 (sv) 2001-12-28 2001-12-28 Hemocue Ab Analysis method and cuvette therefor
US7713474B2 (en) 2002-01-15 2010-05-11 Siemens Healthcare Diagnostics Inc. Liquid permeable composition in dry reagent devices
US7133547B2 (en) 2002-01-24 2006-11-07 Tripath Imaging, Inc. Method for quantitative video-microscopy and associated system and computer software program product
CA2471018A1 (en) 2002-01-28 2003-08-07 Burstein Technologies, Inc. Methods and apparatus for logical triggering of an optical bio-disc
JP5132867B2 (ja) 2002-02-22 2013-01-30 オリンパス アメリカ インコーポレイテツド 仮想顕微鏡スライドを形成し使用する方法および装置、ならびにプログラム
US20030161514A1 (en) 2002-02-28 2003-08-28 Curry Bo U. Bi-directional scanner control system
DE10246777A1 (de) 2002-03-21 2003-10-02 Endress & Hauser Wetzer Gmbh Vorrichtung zur Identifizierung eines Probennehmerbehälters
DE10217404A1 (de) 2002-04-18 2003-11-06 Leica Microsystems Autofokusverfahren für ein Mikroskop und System zum Einstellen des Fokus für ein Mikroskop
US6658143B2 (en) 2002-04-29 2003-12-02 Amersham Biosciences Corp. Ray-based image analysis for biological specimens
WO2003093469A2 (en) 2002-05-01 2003-11-13 Chromos Molecular Systems, Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US7272252B2 (en) 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
MXPA05000063A (es) 2002-07-01 2005-04-08 Kenneth S Warren Inst Inc Citocinas recombinantes protectoras de tejido y acidos nucleicos que las codifican para la proteccion, restauracion y mejora de celulas, tejidos y organos respondedores.
JP2004061942A (ja) 2002-07-30 2004-02-26 Nikon Corp 顕微鏡システム
US7838296B2 (en) 2002-08-28 2010-11-23 Separation Technology, Inc. Methods and apparatus for ultrasonic determination of red blood cell indices
US7177767B2 (en) 2002-10-18 2007-02-13 Abaxis, Inc. Systems and methods for the detection of short and long samples
JP3904505B2 (ja) 2002-10-22 2007-04-11 独立行政法人科学技術振興機構 マラリア感染診断剤及びマラリア原虫染色剤
DE10254685A1 (de) 2002-11-22 2004-06-03 Roche Diagnostics Gmbh Messeinrichtung zur optischen Untersuchung eines Testelements
US7490085B2 (en) 2002-12-18 2009-02-10 Ge Medical Systems Global Technology Company, Llc Computer-assisted data processing system and method incorporating automated learning
US20040132171A1 (en) 2003-01-06 2004-07-08 Peter Rule Wearable device for measuring analyte concentration
WO2004069409A2 (en) 2003-01-31 2004-08-19 Discovery Partners International Automated sample analysis system and method
JP3869810B2 (ja) 2003-02-24 2007-01-17 株式会社堀場製作所 マイクロ血球カウンタ
US6955872B2 (en) 2003-03-20 2005-10-18 Coulter International Corp. Dye compositions which provide enhanced differential fluorescence and light scatter characteristics
US7346205B2 (en) 2003-03-27 2008-03-18 Bartron Medical Imaging, Llc System and method for rapidly identifying pathogens, bacteria and abnormal cells
US7369696B2 (en) 2003-04-02 2008-05-06 Ge Healthcare Uk Limited Classification of cells into subpopulations using cell classifying data
US7706862B2 (en) 2003-04-17 2010-04-27 Research Foundation Of The City University Of New York Detecting human cancer through spectral optical imaging using key water absorption wavelengths
US7329537B2 (en) 2003-04-17 2008-02-12 Nexcelom Bioscience, Llc Micro-pattern embedded plastic optical film device for cell-based assays
US7324694B2 (en) 2003-05-23 2008-01-29 International Remote Imaging Systems, Inc. Fluid sample analysis using class weights
DE10324248A1 (de) 2003-05-28 2005-01-05 Bayerische Motoren Werke Ag Kunststoffträger und Verfahren zu seiner Herstellung
US20040241677A1 (en) 2003-05-29 2004-12-02 Lin Jeffrey S Techniques for automated diagnosis of cell-borne anomalies with digital optical microscope
CA2529016A1 (en) 2003-06-12 2004-12-23 Accupath Diagnostic Laboratories, Inc. Method and system for the analysis of high density cells samples
EP1649038B1 (en) 2003-06-26 2014-07-02 Litron Laboratories Ltd. Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates
ES2661168T3 (es) 2003-07-12 2018-03-27 Accelerate Diagnostics, Inc. Biodetección sensible y rápida
KR100573621B1 (ko) 2003-07-18 2006-04-25 주식회사 디지탈바이오테크놀러지 세포 개체수 계수용 장치 및 그 제조방법
US7411680B2 (en) 2003-07-19 2008-08-12 Digital Bio Technology Device for counting micro particles
SE0302114D0 (sv) 2003-07-21 2003-07-21 Cellavision Ab Sätt att urskilja en objektkontur
WO2005010495A2 (en) 2003-07-22 2005-02-03 Trestle Corporation System and method for generating digital images of a microscope slide
WO2005017025A2 (en) 2003-08-15 2005-02-24 The President And Fellows Of Harvard College Study of polymer molecules and conformations with a nanopore
US7998435B2 (en) 2003-09-19 2011-08-16 Life Technologies Corporation High density plate filler
US20060233671A1 (en) 2003-09-19 2006-10-19 Beard Nigel P High density plate filler
WO2005050479A1 (ja) 2003-11-21 2005-06-02 National University Corporation Kochi University 類似パターン検索装置、類似パターン検索方法、類似パターン検索プログラム、および分画分離装置
US7030351B2 (en) 2003-11-24 2006-04-18 Mitutoyo Corporation Systems and methods for rapidly automatically focusing a machine vision inspection system
DE602005016527D1 (de) 2004-02-09 2009-10-22 Rapid Pathogen Screening Inc Verfahren zur schnelldiagnose von zielen in menschlichen körperflüssigkeiten
WO2005076050A1 (en) 2004-02-09 2005-08-18 Philips Intellectual Property & Standards Gmbh Fluorescence microscope arrangement
US9176121B2 (en) 2004-02-13 2015-11-03 Roche Diagnostics Hematology, Inc. Identification of blood elements using inverted microscopy
JP4417143B2 (ja) 2004-03-11 2010-02-17 シスメックス株式会社 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体
WO2005089945A1 (en) 2004-03-12 2005-09-29 Biotrove, Inc. Nanoliter array loading
US7925070B2 (en) 2004-03-30 2011-04-12 Sysmex Corporation Method for displaying virtual slide and terminal device for displaying virtual slide
US20060051778A1 (en) 2004-03-31 2006-03-09 Kallick Charles A Diagnosis of systemic lupus erythematosus
WO2005100539A2 (en) 2004-04-07 2005-10-27 Levine, Robert, A. Disposable chamber for analyzing biologic fluids
WO2005121863A1 (en) 2004-06-11 2005-12-22 Nicholas Etienne Ross Automated diagnosis of malaria and other infections
ATE479918T1 (de) 2004-06-17 2010-09-15 Koninkl Philips Electronics Nv Autofocus-mechanismus für ein spektroskopisches system
GB0414201D0 (en) 2004-06-24 2004-07-28 Fujifilm Electronic Imaging Method and apparatus for forming a multiple focus stack image
US20060002817A1 (en) 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
US8582924B2 (en) 2004-06-30 2013-11-12 Carl Zeiss Microimaging Gmbh Data structure of an image storage and retrieval system
US7456377B2 (en) 2004-08-31 2008-11-25 Carl Zeiss Microimaging Ais, Inc. System and method for creating magnified images of a microscope slide
US20060063185A1 (en) 2004-09-09 2006-03-23 Edouard Vannier Methods for detection of pathogens in red blood cells
US20060095241A1 (en) 2004-10-29 2006-05-04 Microsoft Corporation Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails
WO2006040387A1 (en) 2004-10-11 2006-04-20 Thermo Fisher Scientific Oy Method for automatically detecting factors that disturb analysis by a photometer
US8045782B2 (en) 2004-12-07 2011-10-25 Ge Healthcare Niagara, Inc. Method of, and apparatus and computer software for, implementing image analysis protocols
EP1875203B1 (en) 2004-12-13 2011-05-04 Bayer HealthCare LLC Transmission spectroscopy system for use in the determination of analytes in body fluid
JP4840940B2 (ja) 2004-12-13 2011-12-21 バイエル・ヘルスケア・エルエルシー 自蔵型検査センサ
US20090258347A1 (en) 2004-12-14 2009-10-15 University Of The Witwatersrand Method for diagnosing and monitoring cellular reservoirs of disease
US20070103678A1 (en) 2005-02-14 2007-05-10 Sterling Bernhard B Analyte detection system with interferent identification and correction
US20060223052A1 (en) 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Technique for detecting microorganisms
PL1866637T3 (pl) 2005-04-01 2016-07-29 Polymer Technology Systems Inc Składnik do badania płynu ustrojowego do detekcji analitu
US7580120B2 (en) 2005-04-07 2009-08-25 Sysmex Corporation Blood analyzer, sample analyzer, and flow cytometer
JP2006301270A (ja) 2005-04-20 2006-11-02 Hitachi Kokusai Electric Inc オートフォーカス装置及びオートフォーカス方法
JP4667944B2 (ja) 2005-04-20 2011-04-13 シスメックス株式会社 画像作成装置
FR2884920B1 (fr) 2005-04-21 2007-08-10 Horiba Abx Sa Sa Dispositif et procede d'analyse multiparametrique d'elements microscopiques
CN101171346B (zh) 2005-05-06 2011-11-09 三星电子股份有限公司 数字生物盘、数字生物盘驱动器装置及其应用化验方法
AT501944B1 (de) 2005-06-15 2007-06-15 Tissuegnostics Gmbh Verfahren zum segmentieren von leukozyten
US7417213B2 (en) 2005-06-22 2008-08-26 Tripath Imaging, Inc. Apparatus and method for rapid microscopic image focusing having a movable objective
US7993585B2 (en) 2005-07-14 2011-08-09 Battelle Memorial Institute Biological and chemical monitoring
US20070031056A1 (en) 2005-08-02 2007-02-08 Perz Cynthia B System for and method of focusing in automated microscope systems
JP2007040814A (ja) 2005-08-03 2007-02-15 Matsushita Electric Ind Co Ltd 吸光度測定用センサ及び吸光度測定方法
US7776553B2 (en) 2005-09-16 2010-08-17 Presidents And Fellows Of Harvard College Screening assays and methods
US7609369B2 (en) 2005-09-24 2009-10-27 Beckman Coulter, Inc. Methods of detection of iron deficiency and hemochromatosis
US7796797B2 (en) 2005-09-28 2010-09-14 Sysmex Corporation Apparatus for obtaining an image of a blood cell and method for obtaining an image of a blood cell
US7599893B2 (en) 2005-10-13 2009-10-06 Aureon Laboratories, Inc. Methods and systems for feature selection in machine learning based on feature contribution and model fitness
GB2431537B (en) 2005-10-20 2011-05-04 Amersham Biosciences Uk Ltd Method of processing an image
US7344890B2 (en) 2005-11-09 2008-03-18 Beckman Coulter, Inc. Method for discriminating platelets from red blood cells
US7933435B2 (en) 2005-11-21 2011-04-26 Vala Sciences, Inc. System, method, and kit for processing a magnified image of biological material to identify components of a biological object
US20100068747A1 (en) 2005-12-01 2010-03-18 Evotec Technologies Gmbh Generic Assay for Monitoring Endocytosis
JP4925364B2 (ja) 2006-01-20 2012-04-25 ベックマン コールター， インコーポレイテッド 鉄欠乏を検出する方法
SE529536C2 (sv) 2006-01-25 2007-09-04 Hemocue Ab Metod för säkerställande av en provbehållares kvalitet
GB2435925A (en) 2006-03-09 2007-09-12 Cytokinetics Inc Cellular predictive models for toxicities
SE530244C2 (sv) 2006-05-05 2008-04-08 Hemocue Ab Förfarande och system för kvantitativ hemoglobinbestämning
CN101438147B (zh) 2006-05-31 2011-09-28 奥林巴斯株式会社 生物试样摄像方法及生物试样摄像装置
CN101501785A (zh) 2006-06-02 2009-08-05 维克托·B·克利 针对米到亚纳米长度范围内的高速测量、分析和成像的系统及方法
JP5040191B2 (ja) 2006-06-29 2012-10-03 富士通株式会社 マイクロインジェクション装置及び自動焦点調整方法
AT503862B1 (de) 2006-07-05 2010-11-15 Arc Austrian Res Centers Gmbh Pathogen-identifizierung anhand eines 16s oder 18s-rrna mikroarray
DE102006031177A1 (de) 2006-07-06 2008-01-10 Carl Zeiss Microimaging Gmbh Verfahren und Vorrichtung zur Erzeugung eines Bildes einer dünnen Schicht eines Objekts
SE530750C2 (sv) 2006-07-19 2008-09-02 Hemocue Ab En mätapparat, en metod och ett datorprogram
US8067245B2 (en) 2006-07-24 2011-11-29 Medica Corporation Automated microscope for blood cell analysis
US7542137B2 (en) 2006-07-24 2009-06-02 University Of Ottawa Pathogen detection using coherent anti-stokes Raman scattering microscopy
US8428331B2 (en) 2006-08-07 2013-04-23 Northeastern University Phase subtraction cell counting method
EP2076587A4 (en) 2006-09-11 2009-12-09 Univ Florida ISOLATION, EXPANSION AND USE OF TUMOR STAMMING CELLS
WO2008063135A1 (en) 2006-11-24 2008-05-29 Agency For Science, Technology And Research Apparatus for processing a sample in a liquid droplet and method of using the same
KR100844350B1 (ko) 2007-01-09 2008-07-07 주식회사 디지탈바이오테크놀러지 부유 혼합 미세입자 중 특정 미세입자를 광학적인 방법으로계수하기 위한 미세채널 칩 및 이를 이용한 미세입자 계수방법
EP2104920B1 (en) 2007-01-11 2015-03-04 Intellectual Property MVM B.V. The measurement of functional microcirculatory geometry and velocity distributions using automated image analysis
US7738094B2 (en) 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
EP2115424B1 (en) 2007-02-02 2018-10-24 Canadian Blood Services Method of detecting bacterial contamination using dynamic light scattering
EP2109856B1 (en) 2007-02-05 2019-01-16 Siemens Healthcare Diagnostics Inc. System and method for cell analysis in microscopy
GB0704035D0 (en) 2007-03-02 2007-04-11 Smiths Detection Watford Ltd Sample preparation apparatus
JP5105945B2 (ja) 2007-04-19 2012-12-26 キヤノン株式会社 雲台装置及びその制御方法
DE102007021387A1 (de) 2007-05-04 2008-11-06 Eads Deutschland Gmbh Detektionsvorrichtung zur Detektion von biologischen Mikropartikeln wie Bakterien, Viren, Sporen, Pollen oder biologische Toxine, sowie Detektionsverfahren
US20080305514A1 (en) 2007-06-06 2008-12-11 Alcon Research, Ltd. Method for detecting microbes
KR100900511B1 (ko) 2007-07-23 2009-06-03 주식회사 디지탈바이오테크놀러지 유체분석용 칩
WO2009018473A1 (en) 2007-07-31 2009-02-05 Micronics, Inc. Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays
CA2604317C (en) * 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
US7936913B2 (en) 2007-08-07 2011-05-03 Nextslide Imaging Llc Network image review in clinical hematology
US20090040325A1 (en) * 2007-08-09 2009-02-12 Beecher Jr Thomas C Methods for remote imaging and systems thereof
US8878923B2 (en) 2007-08-23 2014-11-04 General Electric Company System and method for enhanced predictive autofocusing
CN101387599B (zh) 2007-09-13 2011-01-26 深圳迈瑞生物医疗电子股份有限公司 一种区分粒子群落的方法及粒子分析仪
EP2193154A1 (en) 2007-09-21 2010-06-09 Dow Global Technologies Inc. Prepolymers and polymers for elastomers
WO2009041918A1 (en) 2007-09-26 2009-04-02 Agency For Science, Technology And Research A method and system for generating an entirely well-focused image of a large three-dimensional scene
CN104297506B (zh) 2007-10-02 2017-05-03 赛拉诺斯股份有限公司 模块化现场护理装置及其应用
JP2009109198A (ja) 2007-10-26 2009-05-21 Arkray Inc 分析装置
KR101009447B1 (ko) 2007-11-12 2011-01-19 바디텍메드 주식회사 체액 샘플링, 전처리 및 투입장치 및 방법
US8125512B2 (en) 2007-11-16 2012-02-28 Samsung Electronics Co., Ltd. System and method for moving object selection in a handheld image capture device
WO2009088930A2 (en) 2008-01-02 2009-07-16 The Regents Of The University Of California High numerical aperture telemicroscopy apparatus
US20090185734A1 (en) 2008-01-18 2009-07-23 Hemocue Ab Apparatus and method for analysis of particles in a liquid sample
JP4558047B2 (ja) 2008-01-23 2010-10-06 オリンパス株式会社 顕微鏡システム、画像生成方法、及びプログラム
JP5365011B2 (ja) * 2008-01-29 2013-12-11 日本電気株式会社 病理診断支援装置、病理診断支援方法、およびプログラム
EP2255338A2 (en) 2008-03-12 2010-12-01 Koninklijke Philips Electronics N.V. Correction of spot area in measuring brightness of sample in biosensing device
ES2588223T3 (es) 2008-03-21 2016-10-31 Abbott Point Of Care, Inc. Procedimiento para el análisis de células individuales o partículas en la sangre usando fluorescencia y absorción de un colorante
ES2560098T3 (es) 2008-03-21 2016-02-17 Abbott Point Of Care, Inc. Método y aparato para detectar y contar plaquetas individualmente y en agregados
CN102016578B (zh) 2008-03-21 2014-10-01 艾博特健康公司 利用红细胞内含有的血红蛋白的本征色素沉着来确定血样的血细胞比容的方法及设备
EP2265945B1 (en) 2008-03-21 2012-11-07 Abbott Point Of Care, Inc. Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
JP2009233927A (ja) 2008-03-26 2009-10-15 Toshiba Tec Corp インクジェットヘッドの製造方法
US8628729B2 (en) 2008-03-27 2014-01-14 President And Fellows Of Harvard College Three-dimensional microfluidic devices
US8883491B2 (en) 2008-04-09 2014-11-11 Nexcelom Bioscience Llc Systems and methods for counting cells and biomolecules
JP2012515931A (ja) 2008-04-25 2012-07-12 ウィンケルマン、ジェイムズ 全血球数及び白血球百分率を決定するシステム及び方法
US8379944B2 (en) 2008-04-29 2013-02-19 Siemens Healthcare Diagnostics Inc. Identification, classification and counting of targets of interest in multispectral image data
EP2293062B1 (en) * 2008-05-09 2015-01-28 Sysmex Corporation Blood analyzer, blood analysis method, hemolytic agent and staining agent
EP2280278A4 (en) * 2008-05-09 2015-04-08 Sysmex Corp Blood analyzer, blood analysis method and hemolysis
JP2009268432A (ja) 2008-05-09 2009-11-19 Canon Inc 標的核酸の測定方法
CA2724973C (en) 2008-05-20 2015-08-11 University Health Network Device and method for fluorescence-based imaging and monitoring
WO2009157385A1 (ja) 2008-06-27 2009-12-30 古河電気工業株式会社 細胞の識別およびソーティング方法およびその装置
DE102008030874A1 (de) 2008-06-30 2010-01-07 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zum Ermitteln einer Kontur und eines Mittelpunktes eines Objekts
KR20100007809A (ko) 2008-07-14 2010-01-22 삼성전자주식회사 미세유동장치, 이를 이용한 시료분석방법 및 희석비율측정방법
US8385971B2 (en) 2008-08-19 2013-02-26 Digimarc Corporation Methods and systems for content processing
WO2010025302A2 (en) 2008-08-27 2010-03-04 Life Technologies Corporation Apparatus for and method of processing biological samples
CN102165489B (zh) 2008-09-16 2015-11-25 赫斯托克斯公司 生物标志物表达的可再现量化
US8280134B2 (en) 2008-09-22 2012-10-02 Cambridge Research & Instrumentation, Inc. Multi-spectral imaging including at least one common stain
CN102224410B (zh) 2008-09-24 2017-02-08 施特劳斯控股公司 用于测试分析物的成像分析仪
JP5380973B2 (ja) 2008-09-25 2014-01-08 株式会社ニコン 画像処理装置及び画像処理プログラム
WO2010044870A1 (en) 2008-10-14 2010-04-22 The Burnham Institute For Medical Research Automated scanning cytometry using chromatic aberration for multiplanar image acquisition
US8842900B2 (en) 2008-10-28 2014-09-23 Sysmex Corporation Specimen processing system and blood cell image classifying apparatus
US8192995B2 (en) 2008-11-13 2012-06-05 Beckman Coulter, Inc. Method of correction of particle interference to hemoglobin measurement
CN101403650B (zh) 2008-11-21 2010-06-23 北京理工大学 差动共焦组合超长焦距测量方法与装置
JP2012510069A (ja) 2008-11-27 2012-04-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 無染色生物試料の多色画像の生成
US20100157086A1 (en) 2008-12-15 2010-06-24 Illumina, Inc Dynamic autofocus method and system for assay imager
GB0900526D0 (en) 2009-01-14 2009-02-11 Perkinelmer Ltd Fluorescence microscopy methods and apparatus
JP5426181B2 (ja) 2009-01-21 2014-02-26 シスメックス株式会社 検体処理システム、細胞画像分類装置、及び検体処理方法
EP2216095A1 (en) 2009-01-27 2010-08-11 Koninklijke Philips Electronics N.V. Microfluidic device for full blood count
JP2011095225A (ja) * 2009-11-02 2011-05-12 Olympus Corp 画像処理装置、画像処理方法および顕微鏡システム
US9778188B2 (en) 2009-03-11 2017-10-03 Industrial Technology Research Institute Apparatus and method for detection and discrimination molecular object
CN103251375B (zh) 2009-04-01 2016-09-28 眼泪科学公司 用于成像和测量泪液膜层一个或多个厚度的仪器
US9470609B2 (en) 2009-04-09 2016-10-18 Koninklijke Philips N. V. Preparation of thin layers of a fluid containing cells for analysis
AU2010241731B2 (en) 2009-04-27 2015-08-06 Roche Diagnostics Hematology, Inc. Systems and methods for analyzing body fluids
JP5424712B2 (ja) 2009-05-21 2014-02-26 キヤノン株式会社 画像処理装置及びその制御方法とプログラム
US20100300563A1 (en) 2009-05-27 2010-12-02 John Ramunas Modular device and method for moving fluids to and from a sample delivery element
WO2010137543A1 (ja) 2009-05-27 2010-12-02 株式会社日立ハイテクノロジーズ 核酸分析用デバイス、核酸分析装置、及び核酸分析方法
US8891851B2 (en) 2009-07-15 2014-11-18 Glenn F. Spaulding Home healthcare management system and hardware
US8481303B2 (en) 2009-10-12 2013-07-09 Corning Incorporated Microfluidic device for cell culture
US8320655B2 (en) 2009-10-16 2012-11-27 General Electric Company Process and system for analyzing the expression of biomarkers in cells
CA2842723C (en) 2009-10-19 2016-02-16 Ventana Medical Systems, Inc. Imaging system and techniques
WO2011056658A1 (en) 2009-10-27 2011-05-12 Duke University Multi-photon microscopy via air interface objective lens
JP5394887B2 (ja) 2009-10-29 2014-01-22 オリンパス株式会社 顕微鏡装置および顕微鏡観察方法
CN102053051A (zh) 2009-10-30 2011-05-11 西门子公司 一种体液分析系统和用于体液分析的图像处理设备、方法
US20120058504A1 (en) 2009-10-30 2012-03-08 Simon Fraser University Methods and apparatus for dielectrophoretic shuttling and measurement of single cells or other particles in microfluidic chips
US9072772B2 (en) 2009-11-05 2015-07-07 University of Pittsburgh—of the Commonwealth System of Higher Education Methods of treating disorders associated with protein aggregation
US9119573B2 (en) 2009-12-10 2015-09-01 Siemens Aktiengesellschaft Stent marker detection using a learning based classifier in medical imaging
US8748186B2 (en) 2009-12-22 2014-06-10 Abbott Laboratories Method for performing a blood count and determining the morphology of a blood smear
WO2011076413A1 (en) 2009-12-22 2011-06-30 Universität Heidelberg Means and methods for detecting plasmodia and for screening or diagnosing drug resistance or altered drug responsiveness of plasmodia
US8237786B2 (en) 2009-12-23 2012-08-07 Applied Precision, Inc. System and method for dense-stochastic-sampling imaging
ES2438841T3 (es) 2009-12-31 2014-01-20 Abbott Point Of Care, Inc. Método y aparato para determinar el volumen celular medio de los glóbulos rojos en la sangre
US8906308B2 (en) 2010-01-15 2014-12-09 Abbott Laboratories Method for determining volume and hemoglobin content of individual red blood cells
US8928876B2 (en) 2010-01-20 2015-01-06 Nexcelom Bioscience Llc Cell counting and sample chamber and methods of fabrication
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
JP5490568B2 (ja) 2010-02-26 2014-05-14 オリンパス株式会社 顕微鏡システム、標本観察方法およびプログラム
US9199233B2 (en) 2010-03-31 2015-12-01 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge with deflecting top panel
SG174650A1 (en) 2010-03-31 2011-10-28 Agency Science Tech & Res A method of monitoring parasite development in blood
US8396269B2 (en) 2010-04-08 2013-03-12 Digital Pathco LLC Image quality assessment including comparison of overlapped margins
US8040517B1 (en) 2010-04-30 2011-10-18 General Electric Company Arc flash detection system and method
WO2011143075A2 (en) 2010-05-08 2011-11-17 Veridex, Llc A simple and affordable method for immuophenotyping using a microfluidic chip sample preparation with image cytometry
JP5864559B2 (ja) * 2010-06-04 2016-02-17 ライカ バイオシステムズ イメージング インコーポレイテッドＡｐｅｒｉｏ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． デジタル化された顕微鏡スライドのスライド品質を判断するシステム及び方法
US9028388B2 (en) 2010-06-07 2015-05-12 Terumo Bct, Inc. Multi-unit blood processor with volume prediction
WO2012000102A1 (en) 2010-06-30 2012-01-05 The Governors Of The University Of Alberta Apparatus and method for microscope-based label-free microflutdic cytometry
WO2012006565A2 (en) 2010-07-08 2012-01-12 Life Technologies Corporation Systems and methods for assigning attributes to a plurality of samples
US20150032671A9 (en) 2010-07-23 2015-01-29 General Electric Company Systems and methods for selecting and analyzing particles in a biological tissue
US10139613B2 (en) 2010-08-20 2018-11-27 Sakura Finetek U.S.A., Inc. Digital microscope and method of sensing an image of a tissue sample
EP2613151B1 (en) 2010-09-02 2016-06-29 Tohoku University Method for determining cancer onset or cancer onset risk
US8933927B2 (en) 2010-09-02 2015-01-13 Samsung Electronics Co., Ltd. Display system with image conversion mechanism and method of operation thereof
US8891850B2 (en) 2010-09-16 2014-11-18 The University Of Kansas System and methods for digital evaluation of cellblock preparations
US8351676B2 (en) 2010-10-12 2013-01-08 Sony Corporation Digital image analysis using multi-step analysis
US8542274B2 (en) 2010-10-18 2013-09-24 Olympus America Inc. Wide field microscopic imaging system and method
USD655421S1 (en) 2010-11-03 2012-03-06 Life Technologies Corporation Cell counter
WO2012075263A1 (en) 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Assay devices with integrated sample dilution and dilution verification and methods of using same
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
JP5331828B2 (ja) 2011-01-14 2013-10-30 株式会社日立ハイテクノロジーズ 荷電粒子線装置
EP2686828A1 (en) 2011-03-14 2014-01-22 The University Of Warwick Histology analysis
US8982206B2 (en) 2011-04-07 2015-03-17 Uwm Research Foundation, Inc. High speed microscope with narrow detector and pixel binning
US9064301B2 (en) 2011-04-14 2015-06-23 Abbott Point Of Care, Inc. Method and apparatus for compressing imaging data of whole blood sample analyses
ES2961409T3 (es) 2011-04-15 2024-03-11 Roche Diagnostics Hematology Inc Sistema y procedimiento para determinar un volumen plaquetario para una muestra de sangre, programa informático y medio legible por ordenador
WO2012171182A1 (en) 2011-06-14 2012-12-20 Hangzhou Everlong Biotechnics, Co., Ltd. Target-directed, magnetically enhanced system for detoxification of patients
TWI493505B (zh) 2011-06-20 2015-07-21 晨星半導體股份有限公司 影像處理方法以及影像處理裝置
US10426356B2 (en) 2011-07-09 2019-10-01 Gauss Surgical, Inc. Method for estimating a quantity of a blood component in a fluid receiver and corresponding error
US9652655B2 (en) 2011-07-09 2017-05-16 Gauss Surgical, Inc. System and method for estimating extracorporeal blood volume in a physical sample
KR20160103175A (ko) * 2011-07-19 2016-08-31 오비지오 이미징 시스템스 엔.브이. 세포 샘플에서의 암 세포들의 검출 및/또는 분류를 위한 방법 및 시스템
CA2842699A1 (en) * 2011-07-22 2013-01-31 Roche Diagnostics Hematology, Inc. Identifying and measuring reticulocytes
JP5959814B2 (ja) 2011-08-08 2016-08-02 ソニー株式会社 血液分析装置および血液分析方法
WO2013037119A1 (zh) * 2011-09-16 2013-03-21 长沙高新技术产业开发区爱威科技实业有限公司 红细胞形态学分析装置及其方法
EP2758765B1 (en) 2011-09-22 2020-08-12 FOCE Technology International B.V. Optical platelet counter method
US9046473B2 (en) 2011-09-28 2015-06-02 Abbott Point Of Care, Inc. Method and apparatus for detecting the presence of intraerythrocytic parasites
WO2013056379A1 (en) 2011-10-19 2013-04-25 Biovotion Ag System for noninvasive optical measurements of physiological properties in tissue
TWI431264B (zh) 2011-10-20 2014-03-21 Lite On It Corp 光學偵測裝置及光學量測系統
US8885912B2 (en) 2011-11-03 2014-11-11 General Electric Company Generate percentage of positive cells for biomarkers by normalizing and autothresholding the image intensity produced by immunohistochemistry technique
US9028778B2 (en) * 2011-12-28 2015-05-12 Abbott Laboratories Accelerated Wright-Giemsa and May-Grünwald staining methods
CN104169719B (zh) 2011-12-29 2017-03-08 思迪赛特诊断有限公司 用于检测生物样品中病原体的方法和系统
CN104080534B (zh) 2011-12-30 2017-05-24 艾博特健康公司 用于使生物流体样品快速成像的方法
EP2798352B1 (en) 2011-12-30 2015-11-25 Abbott Point Of Care, Inc. Method and apparatus for automated platelet identification within a whole blood sample from microscopy images
WO2013158506A2 (en) 2012-04-17 2013-10-24 Ehrenkranz Joel R L Device for performing a blood, cell, and/or pathogen count and methods for use thereof
US20150072880A1 (en) 2012-05-09 2015-03-12 David A. Calderwood Rapid detection of analytes in liquid samples
FR2991457B1 (fr) 2012-06-01 2014-07-18 Commissariat Energie Atomique Procede et systeme de caracterisation de la vitesse de deplacement de particules contenues dans un liquide, telles que des particules sanguines
US8873827B2 (en) 2012-06-29 2014-10-28 General Electric Company Determination of spatial proximity between features of interest in biological tissue
US8992750B1 (en) 2012-07-02 2015-03-31 Roche Diagnostics Operations, Inc. Biosensor and methods for manufacturing
US8744165B2 (en) 2012-07-19 2014-06-03 Sony Corporation Method and apparatus for stain separation in digital pathology images
JP5333635B1 (ja) 2012-08-23 2013-11-06 富士ゼロックス株式会社 画像処理装置、プログラム及び画像処理システム
JP5464244B2 (ja) 2012-08-24 2014-04-09 富士ゼロックス株式会社 画像処理装置、プログラム及び画像処理システム
EP2731051A1 (en) 2012-11-07 2014-05-14 bioMérieux Bio-imaging method
US9400414B2 (en) 2012-11-19 2016-07-26 Raytheon Company Methods and apparatus for imaging without retro-reflection using a tilted image plane and structured relay optic
EP2927311B1 (en) 2012-11-28 2019-11-20 Japan Science And Technology Agency Cell observation device, cell observation method and program thereof
EP2929345A4 (en) 2012-12-06 2015-11-18 Abbott Point Of Care Inc ILLUSTRATION OF BIOLOGICAL FLUIDS BY MEANS OF A PREFERRED DISTRIBUTION
US10502666B2 (en) 2013-02-06 2019-12-10 Alentic Microscience Inc. Sample processing improvements for quantitative microscopy
JP6581965B2 (ja) 2013-03-13 2019-09-25 タホ インスティチュート フォー ルーラル ヘルス リサーチ， エルエルシー 携帯用血液計数モニタ
WO2014159620A1 (en) 2013-03-14 2014-10-02 Samuels Mark A Encoded calibration device and systems and methods thereof
SG11201506786VA (en) 2013-03-15 2015-09-29 Richard Harry Turner A system and methods for the in vitro detection of particles and soluble chemical entities in body fluids
US9064304B2 (en) * 2013-03-18 2015-06-23 General Electric Company Image quality assessment of microscopy images
EP3869257B1 (en) 2013-05-23 2024-05-08 S.D. Sight Diagnostics Ltd. Method and system for imaging a cell sample
IL227276A0 (en) 2013-07-01 2014-03-06 Parasight Ltd A method and system for preparing a monolayer of cells, particularly suitable for diagnosis
JP2015021938A (ja) * 2013-07-23 2015-02-02 シスメックス株式会社 検体分析装置、疾患監視システムおよび検体分析装置のデータ管理方法
DE102013216362A1 (de) * 2013-08-19 2015-02-19 Siemens Healthcare Diagnostics Products Gmbh Analyseverfahren zur Klassifikationsunterstützung
US10831013B2 (en) 2013-08-26 2020-11-10 S.D. Sight Diagnostics Ltd. Digital microscopy systems, methods and computer program products
GB201318084D0 (en) 2013-10-11 2013-11-27 Isis Innovation Malaria vaccination
WO2015089632A1 (en) 2013-12-17 2015-06-25 Alentic Microscience Inc. Dosimeters including lensless imaging systems
JP6194791B2 (ja) 2013-12-27 2017-09-13 富士ゼロックス株式会社 画像処理装置及びプログラム
WO2015189264A1 (en) 2014-06-10 2015-12-17 Ventana Medical Systems, Inc. Predicting breast cancer recurrence directly from image features computed from digitized immunohistopathology tissue slides
CN107077732B (zh) 2014-08-27 2020-11-24 思迪赛特诊断有限公司 用于对数字显微镜计算聚焦变化的系统及方法
JP6352750B2 (ja) 2014-09-26 2018-07-04 シスメックス株式会社 血液分析装置および血液分析方法
KR20170066498A (ko) 2014-09-29 2017-06-14 칩케어 코포레이션 카트리지 및 유체 칩을 포함하는 세포의 광학적 검출을 위한 장치 및 그 방법
FR3028318B1 (fr) 2014-11-12 2025-10-03 Phuong Lan Tran Procede et dispositif de tri selectif, specifique et simultane de cellules rares cibles dans un echantillon biologique
US11478789B2 (en) 2014-11-26 2022-10-25 Medica Corporation Automated microscopic cell analysis
US20170328924A1 (en) 2014-11-26 2017-11-16 Ronald Jones Automated microscopic cell analysis
WO2018009920A1 (en) 2016-07-08 2018-01-11 Medica Corporation Automated microscopic cell analysis
US10061972B2 (en) 2015-05-28 2018-08-28 Tokitae Llc Image analysis systems and related methods
EP3865832B1 (en) 2015-06-19 2023-12-13 Andrew Alliance S.A Methods for measurement of liquid volumes
JP6461739B2 (ja) 2015-07-28 2019-01-30 富士フイルム株式会社 画像処理装置及び内視鏡システム並びに画像処理装置の作動方法
DE102015113557B4 (de) 2015-08-17 2019-05-02 Gerresheimer Regensburg Gmbh Probenvorrichtung mit Referenzmarkierung
EP3859425B1 (en) 2015-09-17 2024-04-17 S.D. Sight Diagnostics Ltd. Methods and apparatus for detecting an entity in a bodily sample
JP6559555B2 (ja) 2015-12-02 2019-08-14 株式会社日立エルジーデータストレージ 光計測方法および装置
US10416087B2 (en) * 2016-01-01 2019-09-17 Kla-Tencor Corporation Systems and methods for defect detection using image reconstruction
US11733150B2 (en) 2016-03-30 2023-08-22 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
US11307196B2 (en) 2016-05-11 2022-04-19 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
AU2017263807B2 (en) 2016-05-11 2023-02-02 S.D. Sight Diagnostics Ltd Performing optical measurements on a sample
US10281386B2 (en) 2016-05-11 2019-05-07 Bonraybio Co., Ltd. Automated testing apparatus
CA3045333A1 (en) 2016-12-01 2018-06-07 Berkeley Lights, Inc. Automated detection and repositioning of micro-objects in microfluidic devices
CN111183350A (zh) 2017-08-17 2020-05-19 雅培医护站股份有限公司 用于对血细胞成像的单次使用测试设备
JP6505792B2 (ja) 2017-08-29 2019-04-24 富士フイルム株式会社 内視鏡用光源装置及び内視鏡システム
EP3710810B1 (en) 2017-11-14 2023-09-06 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
WO2019102277A1 (en) 2017-11-23 2019-05-31 Sigtuple Technologies Private Limited Method and system for determining hematological parameters in a peripheral blood smear
WO2019198094A1 (en) 2018-04-09 2019-10-17 Sigtuple Technologies Private Limited Method and system for estimating total count of blood cells in a blood smear
JP7678424B2 (ja) 2018-05-10 2025-05-16 学校法人順天堂 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法
KR102931515B1 (ko) 2019-10-22 2026-02-27 에스.디. 사이트 다이그노틱스 엘티디 광학 측정들에서의 오류들의 고려

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12393010B2 (en) 2013-08-26 2025-08-19 S.D. Sight Diagnostics Ltd. Distinguishing between entities in a blood sample
US12196664B2 (en) 2016-03-30 2025-01-14 S.D. Sight Diagnostics Ltd. Distinguishing between blood sample components
US12196940B2 (en) 2017-11-14 2025-01-14 S.D. Sight Diagnostics Ltd. Sample carrier for microscopy and optical density measurements
US12498325B2 (en) 2019-10-22 2025-12-16 S.D. Sight Diagnostics Ltd. Accounting for errors in optical measurements
US12189112B2 (en) 2019-12-12 2025-01-07 S.D. Sight Diagnostics Ltd. Artificial generation of color blood smear image
US12436101B2 (en) 2019-12-12 2025-10-07 S.D. Sight Diagnostics Ltd. Microscopy unit
US12523579B2 (en) 2019-12-12 2026-01-13 S.D. Sight Diagnostics Ltd. Detecting platelets in a blood sample
US12711788B2 (en) 2020-12-10 2026-08-18 S.D. Sight Diagnostics Ltd. Classification models for analyzing a sample

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