JP6340005B2 - ３−エピメラーゼ - Google Patents

３−エピメラーゼ Download PDF

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Publication number
JP6340005B2
JP6340005B2 JP2015533696A JP2015533696A JP6340005B2 JP 6340005 B2 JP6340005 B2 JP 6340005B2 JP 2015533696 A JP2015533696 A JP 2015533696A JP 2015533696 A JP2015533696 A JP 2015533696A JP 6340005 B2 JP6340005 B2 JP 6340005B2
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seq
protein
sequence
fructose
allulose
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JP2015530105A (ja
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ライアン デイビッド ウッダイアー
ライアン デイビッド ウッダイアー
リチャード ダブリュ． アーメントラウト
リチャード ダブリュ． アーメントラウト
Original Assignee
テート アンド ライル イングリーディエンツ アメリカズ エルエルシー
テート アンド ライル イングリーディエンツ アメリカズ エルエルシー
テート アンド ライル テクノロジー リミテッド
テート アンド ライル テクノロジー リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/03—Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2015533696A 2012-09-27 2013-09-27 ３−エピメラーゼ Active JP6340005B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261706338P 2012-09-27 2012-09-27
US61/706,338 2012-09-27
GB1220554.8 2012-11-15
GB1220554.8A GB2508586B (en) 2012-09-27 2012-11-15 A protein
PCT/GB2013/052531 WO2014049373A1 (en) 2012-09-27 2013-09-27 3-epimerase

Publications (2)

Publication Number Publication Date
JP2015530105A JP2015530105A (ja) 2015-10-15
JP6340005B2 true JP6340005B2 (ja) 2018-06-06

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JP2015533696A Active JP6340005B2 (ja) 2012-09-27 2013-09-27 ３−エピメラーゼ

Country Status (16)

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US (4) US9725707B2 (enExample)
EP (2) EP2900827B1 (enExample)
JP (1) JP6340005B2 (enExample)
KR (2) KR20150059760A (enExample)
CN (1) CN104903457A (enExample)
AR (1) AR092712A1 (enExample)
AU (2) AU2013322364B2 (enExample)
CA (1) CA2886514C (enExample)
CL (1) CL2015000757A1 (enExample)
GB (2) GB2583417B (enExample)
IL (1) IL237900B (enExample)
IN (1) IN2015DN03196A (enExample)
MX (2) MX380772B (enExample)
PL (1) PL2900827T3 (enExample)
TW (1) TWI675916B (enExample)
WO (1) WO2014049373A1 (enExample)

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GB2583417B (en) 2012-09-27 2021-03-31 Tate & Lyle Ingredients Americas Llc A protein
KR101473918B1 (ko) 2014-05-28 2014-12-17 대상 주식회사 사이코스 에피머화 효소, 이의 제조방법 및 이를 이용한 사이코스의 제조방법
KR101577147B1 (ko) * 2014-10-01 2015-12-11 경상대학교산학협력단 사이코스의 생산 방법
US20180251749A1 (en) * 2015-03-27 2018-09-06 Archer Daniels Midland Company Fructose to Allulose Conversion
DK3298127T3 (da) 2015-05-22 2022-04-25 Archer Daniels Midland Co Anvendelse af epimerase-enzymer til omdannelse af fructose til allulose
KR102087396B1 (ko) 2015-11-16 2020-03-10 주식회사 삼양사 과당-함유 기질로부터 사이코스를 생산하는 방법
KR101785300B1 (ko) * 2015-12-23 2017-11-15 대상 주식회사 미생물 균체 고정화 장치 및 이를 이용한 미생물 균체 고정화 방법
CN106148311B (zh) * 2016-09-12 2019-06-21 上海立足生物科技有限公司 一种d-阿洛酮糖-3-差向异构酶的突变体及其应用
MX2019002902A (es) * 2016-09-14 2019-07-04 Matsutani Kagaku Kogyo Kk Metodo para producir alulosa epimerasa inmovilizada.
BR112019007257A2 (pt) * 2016-10-11 2019-07-02 Braskem Sa micro-organismos e métodos para a coprodução de etileno glicol e isobuteno
WO2018081557A2 (en) 2016-10-28 2018-05-03 Tate & Lyle Ingredients Americas Llc Method for producing allulose crystals
KR102065155B1 (ko) 2016-12-08 2020-02-11 주식회사 삼양사 사이코스의 제조방법
CN119286951A (zh) 2016-12-14 2025-01-10 博努莫斯有限责任公司 D-阿洛酮糖的酶法生产
CN108239632B (zh) * 2016-12-26 2023-05-05 上海立足生物科技有限公司 一种热稳定性得到改善的d-阿洛酮糖-3-差向异构酶的突变体及其应用
WO2018129275A1 (en) * 2017-01-06 2018-07-12 Greenlight Biosciences, Inc. Cell-free production of sugars
KR101981430B1 (ko) * 2017-06-23 2019-05-23 씨제이제일제당 (주) D-사이코스 붕산염 착물로부터 크로마토그래피를 이용한 d-사이코스의 생산 방법 및 d-사이코스를 포함하는 조성물
HUE072278T2 (hu) * 2017-08-31 2025-11-28 Novozymes As D-pszikóz-3-epimeráz aktivitású polipeptidek és ezeket kódoló polinukleotidok
JP6647619B2 (ja) * 2018-01-24 2020-02-14 松谷化学工業株式会社 熱安定性が向上したケトース ３−エピメラーゼ
WO2019166514A1 (en) 2018-02-28 2019-09-06 C-Lecta Gmbh Enzymatic in-situ fortification of food with functional carbohydrates
BR112021002184A2 (pt) 2018-08-08 2021-05-04 Archer Daniels Midland Company ácido nucleico, microrganismo, proteína, matriz sólida, coluna, método de produção de uma proteína e método de produção de alulose
MX2022000381A (es) * 2019-07-17 2022-04-06 Bonumose Inc Composiciones enzimáticas inmovilizadas para la producción de hexosas.
CN110862980B (zh) * 2019-11-29 2021-05-04 浙江工业大学 一种d-阿洛酮糖3-差向异构酶突变体及其应用
JPWO2022075435A1 (enExample) * 2020-10-09 2022-04-14
EP4000419A1 (de) 2020-11-23 2022-05-25 Savanna Ingredients GmbH Trocknung von allulosekristallen
CN114790469B (zh) * 2021-01-26 2024-03-26 中国科学院天津工业生物技术研究所 一种酶促合成阿洛酮糖的方法
CN115960879B (zh) * 2023-01-30 2025-01-21 江南大学 一种d-阿洛酮糖3-差向异构酶突变体文库的高通量筛选方法及获得的突变体
WO2025111274A2 (en) * 2023-11-20 2025-05-30 Novozymes A/S Epimerase variants and polynucleotides encoding same

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JP3333969B2 (ja) * 1992-10-08 2002-10-15 株式会社林原生物化学研究所 Ｄ−ケトヘキソース・３−エピメラーゼとその製造方法並びに用途
KR100744479B1 (ko) 2005-06-01 2007-08-01 씨제이 주식회사 사이코스 에피머화 효소에 의한 사이코스의 생산 방법
GB0512150D0 (en) 2005-06-15 2005-07-20 Scottish Crop Res Inst Production of L-ascorbic acid
WO2007058086A1 (ja) 2005-11-15 2007-05-24 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo ケトース３－エピメラーゼとその製造方法並びに用途
US8940350B2 (en) 2005-11-23 2015-01-27 The Coca-Cola Company Cereal compositions comprising high-potency sweeteners
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KR20150015030A (ko) * 2007-05-18 2015-02-09 마쓰다니가가꾸고오교가부시끼가이샤 슈크로오스성 감미질을 가지는 신규 감미료, 그 제조법 및 용도
CN100577793C (zh) 2007-12-12 2010-01-06 江南大学 微生物转化d-果糖制备d-阿洛酮糖的菌种和方法
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KR20110035805A (ko) 2009-09-30 2011-04-06 씨제이제일제당 (주) 사이코스-에피머화 효소의 고정화 및 이를 이용한 사이코스의 제조방법
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CN102373230A (zh) * 2010-08-27 2012-03-14 天津工业生物技术研究所 某种梭菌d-塔格糖3-差向异构酶的核苷酸序列及其应用
US9057062B2 (en) 2011-07-06 2015-06-16 Matsutani Chemical Industry Co., Ltd. Enzyme produced by Arthrobacter globiformis
CN103131721B (zh) 2011-11-25 2014-10-29 中国科学院天津工业生物技术研究所 瘤胃菌d-塔格糖3-差向异构酶的核苷酸序列及其应用
US20130316416A1 (en) * 2012-02-23 2013-11-28 Massachusetts Institute Of Technology Engineering microbes and metabolic pathways for the production of ethylene glycol
WO2014025235A1 (ko) 2012-08-10 2014-02-13 주식회사 삼양제넥스 사이코스 에피머화 효소 및 이를 이용한 사이코스로 전환용 조성물
GB2583417B (en) * 2012-09-27 2021-03-31 Tate & Lyle Ingredients Americas Llc A protein
GB201309076D0 (en) 2013-03-15 2013-07-03 Tate & Lyle Ingredients Improved sweetener
GB201309077D0 (en) 2013-03-15 2013-07-03 Tate & Lyle Ingredients Improved sweetener
GB201309079D0 (en) 2013-03-15 2013-07-03 Tate & Lyle Ingredients Improved sweetner

Also Published As

Publication number Publication date
IL237900B (en) 2020-11-30
GB2583417B (en) 2021-03-31
KR20200028039A (ko) 2020-03-13
US11859224B2 (en) 2024-01-02
GB2508586B (en) 2020-09-02
US20190218541A1 (en) 2019-07-18
AU2013322364B2 (en) 2017-01-12
EP3336194B1 (en) 2024-01-10
EP3336194A1 (en) 2018-06-20
US9725707B2 (en) 2017-08-08
GB202007535D0 (en) 2020-07-01
GB2583417A (en) 2020-10-28
US20170306316A1 (en) 2017-10-26
IL237900A0 (en) 2015-05-31
MX380772B (es) 2025-03-12
EP2900827A1 (en) 2015-08-05
US10294469B2 (en) 2019-05-21
CL2015000757A1 (es) 2015-12-18
US20210198648A1 (en) 2021-07-01
MX2020010399A (es) 2020-10-22
TW201418466A (zh) 2014-05-16
WO2014049373A1 (en) 2014-04-03
AU2013322364A1 (en) 2015-05-07
CN104903457A (zh) 2015-09-09
GB2508586A (en) 2014-06-11
JP2015530105A (ja) 2015-10-15
PL2900827T3 (pl) 2018-10-31
CA2886514C (en) 2021-04-13
IN2015DN03196A (enExample) 2015-10-02
KR20150059760A (ko) 2015-06-02
EP2900827B1 (en) 2018-04-25
GB201220554D0 (en) 2013-01-02
US20150210996A1 (en) 2015-07-30
CA2886514A1 (en) 2014-04-03
AU2017201896A1 (en) 2017-04-06
TWI675916B (zh) 2019-11-01
AR092712A1 (es) 2015-04-29
MX2015004060A (es) 2016-02-22

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