JP6043285B2 - 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 - Google Patents
低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 Download PDFInfo
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37006410P | 2010-08-02 | 2010-08-02 | |
| US61/370,064 | 2010-08-02 | ||
| PCT/US2011/046178 WO2012018754A2 (en) | 2010-08-02 | 2011-08-02 | RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016191103A Division JP2017060472A (ja) | 2010-08-02 | 2016-09-29 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
Publications (3)
| Publication Number | Publication Date |
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| JP2013535212A JP2013535212A (ja) | 2013-09-12 |
| JP2013535212A5 JP2013535212A5 (enExample) | 2014-09-04 |
| JP6043285B2 true JP6043285B2 (ja) | 2016-12-14 |
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| JP2013523255A Active JP6043285B2 (ja) | 2010-08-02 | 2011-08-02 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2016191103A Withdrawn JP2017060472A (ja) | 2010-08-02 | 2016-09-29 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2018187896A Withdrawn JP2019013238A (ja) | 2010-08-02 | 2018-10-03 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2020135811A Active JP7065914B2 (ja) | 2010-08-02 | 2020-08-11 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2022072500A Active JP7408717B2 (ja) | 2010-08-02 | 2022-04-26 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2023214692A Active JP7720384B2 (ja) | 2010-08-02 | 2023-12-20 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
Family Applications After (5)
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| JP2016191103A Withdrawn JP2017060472A (ja) | 2010-08-02 | 2016-09-29 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2018187896A Withdrawn JP2019013238A (ja) | 2010-08-02 | 2018-10-03 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2020135811A Active JP7065914B2 (ja) | 2010-08-02 | 2020-08-11 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2022072500A Active JP7408717B2 (ja) | 2010-08-02 | 2022-04-26 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
| JP2023214692A Active JP7720384B2 (ja) | 2010-08-02 | 2023-12-20 | 低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害 |
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| US (8) | US8518907B2 (enExample) |
| EP (2) | EP3330377A1 (enExample) |
| JP (6) | JP6043285B2 (enExample) |
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| AU (5) | AU2011285909B2 (enExample) |
| CA (1) | CA2805265A1 (enExample) |
| WO (1) | WO2012018754A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016121129A (ja) * | 2010-09-20 | 2016-07-07 | メルク・シャープ・エンド・ドーム・コーポレイション | オリゴヌクレオチドの送達のための新規な低分子量カチオン性脂質 |
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| EP2591105B1 (en) | 2010-07-06 | 2017-05-31 | Dicerna Pharmaceuticals, Inc. | Methods and compositions for the specific inhibition of beta-catenin by double-stranded rna |
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| EP2802658A2 (en) * | 2012-01-09 | 2014-11-19 | Novartis AG | Rnai agents to treat beta-catenin related diseases |
| WO2013154128A1 (ja) * | 2012-04-11 | 2013-10-17 | 塩野義製薬株式会社 | 新規動脈硬化症治療用医薬組成物及び動脈硬化症治療薬のスクリーニング方法 |
| EP3358013B1 (en) | 2012-05-02 | 2020-06-24 | Sirna Therapeutics, Inc. | Short interfering nucleic acid (sina) compositions |
| US20150291956A1 (en) * | 2012-10-25 | 2015-10-15 | Phaserx, Inc. | Rna targeted to beta catenin |
| WO2014093746A2 (en) | 2012-12-14 | 2014-06-19 | Dicerna Pharmaceuticals, Inc. | Methods and compositions for the specific inhibition of ckap5 by double-stranded rna |
| CA2928568A1 (en) | 2013-07-26 | 2015-01-29 | Update Pharma Inc. | Combinatorial methods to improve the therapeutic benefit of bisantrene |
| US20160194625A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
| WO2015034925A1 (en) | 2013-09-03 | 2015-03-12 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| EP3169693B1 (en) | 2014-07-16 | 2022-03-09 | ModernaTX, Inc. | Chimeric polynucleotides |
| CN112410338A (zh) * | 2014-11-14 | 2021-02-26 | 沃雅戈治疗公司 | 调节性多核苷酸 |
| EP3265179A4 (en) * | 2015-03-04 | 2018-07-18 | The University of Chicago | Beta-catenin inhibitors in cancer immunotherapy |
| WO2017099238A1 (ja) * | 2015-12-10 | 2017-06-15 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
| AU2017232496B2 (en) * | 2016-03-16 | 2022-11-24 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for the treatment of a beta-catenin-associated disease or disorder |
| MA45469A (fr) * | 2016-04-01 | 2019-02-06 | Avidity Biosciences Llc | Acides nucléiques de bêta-caténine et leurs utilisations |
| US11458106B2 (en) | 2016-05-09 | 2022-10-04 | Astrazeneca Ab | Lipid nanoparticles comprising lipophilic anti-inflammatory agents and methods of use thereof |
| SG11201809699XA (en) | 2016-05-18 | 2018-12-28 | Voyager Therapeutics Inc | Modulatory polynucleotides |
| CN107365771B (zh) * | 2016-08-18 | 2020-11-10 | 广州市锐博生物科技有限公司 | 用于抑制CTNNB1靶基因mRNA表达的寡核酸分子及其成套组合物 |
| KR20190128692A (ko) | 2017-03-28 | 2019-11-18 | 다이서나 파마수이티컬, 인크. | 면역요법을 강화시키기 위한 베타-카테닌 발현의 감소 |
| AU2018350983A1 (en) * | 2017-10-18 | 2020-04-09 | Dicerna Pharmaceuticals, Inc. | Beta catenin nucleic acid inhibitor molecule |
| JP2021509669A (ja) | 2018-01-05 | 2021-04-01 | ディセルナ ファーマシューティカルズ インコーポレイテッド | 免疫療法を強化するためのベータ−カテニン及びidoの発現の低減 |
| CN108549763B (zh) * | 2018-04-09 | 2021-06-01 | 电子科技大学 | 一种用于离子推进器数值模拟的电荷交换碰撞mcc方法 |
| US12109310B2 (en) | 2018-06-28 | 2024-10-08 | Hadi Valadi | Exosome extracellular vesicles and methods of use |
| US11149271B2 (en) * | 2018-09-04 | 2021-10-19 | Macau University Of Science And Technology | Method and pharmaceutical composition for treating cancer |
| UY38617A (es) | 2019-03-18 | 2020-10-30 | Sound Agriculture Company | Control epigenético programable de la expresión genética en plantas |
| EP4129282A4 (en) * | 2020-03-31 | 2024-05-01 | Natural Medicine Institute Of Zhejiang Yangshengtang Co., Ltd. | PHARMACEUTICAL ASSOCIATION AND ITS USE |
| KR20230005933A (ko) | 2020-05-01 | 2023-01-10 | 아이오니스 파마수티컬즈, 인코포레이티드 | Atxn1을 조정하는 화합물 및 방법 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2016121129A (ja) * | 2010-09-20 | 2016-07-07 | メルク・シャープ・エンド・ドーム・コーポレイション | オリゴヌクレオチドの送達のための新規な低分子量カチオン性脂質 |
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