JP5713377B2 - 薬物標的としての天然アンチセンスおよび非コードrna転写物 - Google Patents

薬物標的としての天然アンチセンスおよび非コードrna転写物 Download PDF

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JP5713377B2
JP5713377B2 JP2008548851A JP2008548851A JP5713377B2 JP 5713377 B2 JP5713377 B2 JP 5713377B2 JP 2008548851 A JP2008548851 A JP 2008548851A JP 2008548851 A JP2008548851 A JP 2008548851A JP 5713377 B2 JP5713377 B2 JP 5713377B2
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nucleic acid
antisense
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rna
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ウォールステッド,クラース
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ザ スクリプス リサーチ インスティテュート
ザ スクリプス リサーチ インスティテュート
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JP2008548851A 2005-12-28 2006-12-28 薬物標的としての天然アンチセンスおよび非コードrna転写物 Active JP5713377B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75446305P 2005-12-28 2005-12-28
US60/754,463 2005-12-28
PCT/US2006/062672 WO2007087113A2 (en) 2005-12-28 2006-12-28 Natural antisense and non-coding rna transcripts as drug targets

Related Child Applications (1)

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JP2014169713A Division JP6163467B2 (ja) 2005-12-28 2014-08-22 薬物標的としての天然アンチセンスおよび非コードrna転写物

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JP2009521934A JP2009521934A (ja) 2009-06-11
JP2009521934A5 JP2009521934A5 (https=) 2011-04-28
JP5713377B2 true JP5713377B2 (ja) 2015-05-07

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JP2008548851A Active JP5713377B2 (ja) 2005-12-28 2006-12-28 薬物標的としての天然アンチセンスおよび非コードrna転写物
JP2014169713A Active JP6163467B2 (ja) 2005-12-28 2014-08-22 薬物標的としての天然アンチセンスおよび非コードrna転写物
JP2016085628A Active JP6422463B2 (ja) 2005-12-28 2016-04-21 薬物標的としての天然アンチセンスおよび非コードrna転写物

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JP2014169713A Active JP6163467B2 (ja) 2005-12-28 2014-08-22 薬物標的としての天然アンチセンスおよび非コードrna転写物
JP2016085628A Active JP6422463B2 (ja) 2005-12-28 2016-04-21 薬物標的としての天然アンチセンスおよび非コードrna転写物

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US (3) US8288354B2 (https=)
EP (1) EP1976567B1 (https=)
JP (3) JP5713377B2 (https=)
CN (2) CN101437933B (https=)
WO (1) WO2007087113A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016175920A (ja) * 2005-12-28 2016-10-06 ザ スクリプス リサーチ インスティテュート 薬物標的としての天然アンチセンスおよび非コードrna転写物

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EP2290073A3 (en) 2004-05-28 2011-08-31 Asuragen, Inc. Methods and compositions involving microRNA
EP2302055B1 (en) 2004-11-12 2014-08-27 Asuragen, Inc. Methods and compositions involving miRNA and miRNA inhibitor molecules
KR20090023464A (ko) * 2006-06-08 2009-03-04 가부시키가이샤 아미노 압 가가쿠 유전자 산물의 생산량을 제어하는 방법 및 생산량 제어제
WO2009036332A1 (en) 2007-09-14 2009-03-19 Asuragen, Inc. Micrornas differentially expressed in cervical cancer and uses thereof
AU2008308499A1 (en) * 2007-10-04 2009-04-09 Board Of Regents, The University Of Texas System Modulating gene expression with agRNA and gapmers targeting antisense transcripts
WO2009137807A2 (en) 2008-05-08 2009-11-12 Asuragen, Inc. Compositions and methods related to mirna modulation of neovascularization or angiogenesis
CN102239260B (zh) * 2008-10-03 2017-04-12 库尔纳公司 通过抑制针对载脂蛋白‑a1的天然反义转录物治疗载脂蛋白‑a1相关疾病
US20110237649A1 (en) * 2008-12-04 2011-09-29 Opko Curna, Llc Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirtuin 1
US20110294870A1 (en) * 2008-12-04 2011-12-01 Opko Curna, Llc Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene
ES2629630T3 (es) * 2008-12-04 2017-08-11 Curna, Inc. Tratamiento de enfermedades relacionadas con eritropoyetina (EPO) mediante inhibición del transcrito antisentido natural a EPO
ES2600781T3 (es) 2008-12-04 2017-02-10 Curna, Inc. Tratamiento para enfermedades relacionadas con el factor de crecimiento del endotelio vascular (vegf) mediante la inhibición de transcritos antisentido naturales de vegf
CN102439149B (zh) * 2009-02-12 2018-01-02 库尔纳公司 通过抑制针对胶质细胞衍生神经营养因子(gdnf)的天然反义转录物来治疗gdnf相关的疾病
ES2762610T3 (es) 2009-02-12 2020-05-25 Curna Inc Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF
CN102482677B (zh) * 2009-03-16 2017-10-17 库尔纳公司 通过抑制nrf2的天然反义转录物治疗核因子(红细胞衍生2)‑样2(nrf2)相关疾病
WO2010107740A2 (en) 2009-03-17 2010-09-23 Curna, Inc. Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
ES2609655T3 (es) 2009-05-06 2017-04-21 Curna, Inc. Tratamiento de enfermedades relacionadas con tristetraprolina (TTP) mediante inhibición de transcrito antisentido natural para TTP
CN103223177B (zh) * 2009-05-06 2016-08-10 库尔纳公司 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病
JP5931720B2 (ja) * 2009-05-08 2016-06-08 クルナ・インコーポレーテッド Dmdファミリーに対する天然アンチセンス転写物の抑制によるジストロフィンファミリー関連疾患の治療
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