JP5679997B2 - １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 - Google Patents

１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 Download PDF

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JP5679997B2
JP5679997B2 JP2011548664A JP2011548664A JP5679997B2 JP 5679997 B2 JP5679997 B2 JP 5679997B2 JP 2011548664 A JP2011548664 A JP 2011548664A JP 2011548664 A JP2011548664 A JP 2011548664A JP 5679997 B2 JP5679997 B2 JP 5679997B2
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alkyl
alkoxy
cycloalkyl
hydroxy
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JP2012516871A5 (enExample
JP2012516871A (ja
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エクハルト，マティアス
ヒンメルスバッハ，フランク
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ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • C07—ORGANIC CHEMISTRY
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2011548664A 2009-02-04 2010-02-03 １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤 Active JP5679997B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20681809P 2009-02-04 2009-02-04
US61/206,818 2009-02-04
PCT/EP2010/051262 WO2010089303A1 (en) 2009-02-04 2010-02-03 CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1

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JP2012516871A JP2012516871A (ja) 2012-07-26
JP2012516871A5 JP2012516871A5 (enExample) 2013-03-21
JP5679997B2 true JP5679997B2 (ja) 2015-03-04

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US (1) US8637505B2 (enExample)
EP (1) EP2393807B1 (enExample)
JP (1) JP5679997B2 (enExample)
CA (1) CA2744946A1 (enExample)
WO (1) WO2010089303A1 (enExample)

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