JP4610192B2 - インピーダンス・センサ - Google Patents
インピーダンス・センサ Download PDFInfo
- Publication number
- JP4610192B2 JP4610192B2 JP2003539744A JP2003539744A JP4610192B2 JP 4610192 B2 JP4610192 B2 JP 4610192B2 JP 2003539744 A JP2003539744 A JP 2003539744A JP 2003539744 A JP2003539744 A JP 2003539744A JP 4610192 B2 JP4610192 B2 JP 4610192B2
- Authority
- JP
- Japan
- Prior art keywords
- needle
- skin
- impedance
- fine needle
- reservoir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- BEWKWPGEQDECPX-UHFFFAOYSA-N CCC(C1)C(C)CCC1=C Chemical compound CCC(C1)C(C)CCC1=C BEWKWPGEQDECPX-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M2005/1401—Functional features
- A61M2005/1405—Patient controlled analgesia [PCA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1581—Right-angle needle-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/65—Impedance, e.g. conductivity, capacity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Medical Informatics (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Surgical Instruments (AREA)
Description
2H2O(l)→O2(g)+4H+(aq)+4e−
他方は以下に示す陰極で生じる還元反応である。
2H2O(l)+2e−→H2(g)+OH−
電子数の釣り合いを保つため、陰極での還元反応は陽極での酸化反応の2倍生じなければならない。したがって、陰極での還元反応を2倍して2つの酸化および還元反応を足し合わせると、全体としての反応は、
6H2O(l)+4e−
→2H2(g)+O2(g)+4H+(aq)+4OH−(aq)+4e−
となる。H+とOH−がH2Oを形成し、さらに等式の両辺に現れるイオン種を相殺すると、全体として正味の反応は、
6H2O(l)→2H2(g)+O2(g)
となる。
ngc=nge/(eNA)=7.784×10−6mol/C
ここで、ngeは、上記反応系に投入された電子1個当たりに生成される気体のモル数、すなわち4分の3(3/4)であり、eは1個の電子の電荷であり、NAはアボガドロ定数である。この変換は、例えば3桁を超える大きな体積変化を引き起こし、この体積変化が、リザーバ46から薬を吐出するために利用される。水の水素および酸素への変換が生じると、体積膨張によってフレキシブル膜48が押されて、リザーバ46から薬および任意の担体あるいはその他の化合物や溶媒が、微細針14を通して放出される。
11 接続具
12 投薬器
14 微細針
16 電池
18 プロセッサ
20 ハウジング
22 表示器
24 通信カード
26 電磁石
28 真空ポンプ
30 アクチュエータ
32 インピーダンス・センサ
34 スピーカ
37 圧力センサ
62 先端
Claims (4)
- 特定成分の物質を収容するリザーバと、
前記リザーバと生体の目標部位との間で前記物質が輸送される際に通過するボアを有する第1および第2の針を含む少なくとも2本の針と、
前記第1および第2の針の間で前記目標部位の一部分におけるインピーダンスを、この2本の針が前記目標部位に貫入したときに測定するインピーダンス・センサとを備え、
前記インピーダンスは前記針が前記目標部位の深さまで貫入したことを表し、
前記インピーダンスの変化が自動制御ユニットにより監視され、所望のインピーダンスに達したときに前記自動制御ユニットが前記針の貫入を停止させる経皮的輸送装置。 - 請求項1において、前記針が皮膚を貫通した後で測定されたインピーダンスは、前記針が皮膚を貫通する前に測定されたインピーダンスよりも1桁以上小さい経皮的輸送装置。
- 請求項2において、前記針が適切な深さまで貫入したとき、前記インピーダンスが3桁以上大きく低下する経皮的輸送装置。
- 生体の目標部位へおよび生体の目標部位から特定成分の物質が輸送される際に通過するボアを有する第1および第2の針を含む2本以上の針からなるアレイを前記目標部位内に貫入する手段と、
前記アレイの内の2本の針が前記目標部位に貫入したとき、その2本の針の間で前記目標部位の一部分におけるインピーダンスを測定する手段とを備え、
前記インピーダンスが、前記針が前記目標部位の深さまで貫入したことを表し、
前記インピーダンスの変化を監視して、所望のインピーダンスに達したときに前記針の貫入を停止させる経皮的輸送装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33842501P | 2001-10-26 | 2001-10-26 | |
US39948902P | 2002-07-29 | 2002-07-29 | |
PCT/US2002/033823 WO2003037405A1 (en) | 2001-10-26 | 2002-10-22 | Impedance sensor |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009114991A Division JP2009219887A (ja) | 2001-10-26 | 2009-05-11 | インピーダンス・センサ |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005507714A JP2005507714A (ja) | 2005-03-24 |
JP4610192B2 true JP4610192B2 (ja) | 2011-01-12 |
Family
ID=26991185
Family Applications (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003539742A Pending JP2005525141A (ja) | 2001-10-26 | 2002-10-18 | 微細針輸送装置 |
JP2003539743A Expired - Fee Related JP4612304B2 (ja) | 2001-10-26 | 2002-10-21 | 微細針経皮的輸送装置 |
JP2003539746A Expired - Fee Related JP4610193B2 (ja) | 2001-10-26 | 2002-10-22 | 吸引機構を有する経皮的輸送装置 |
JP2003539745A Pending JP2005507715A (ja) | 2001-10-26 | 2002-10-22 | 電気分解式アクチュエータを有する経皮的輸送装置 |
JP2003539744A Expired - Fee Related JP4610192B2 (ja) | 2001-10-26 | 2002-10-22 | インピーダンス・センサ |
JP2005304325A Pending JP2006081918A (ja) | 2001-10-26 | 2005-10-19 | 蒸気発生式アクチュエータを有する経皮的輸送装置 |
JP2009114992A Pending JP2009219888A (ja) | 2001-10-26 | 2009-05-11 | 吸引機構を有する経皮的輸送装置 |
JP2009114989A Pending JP2009219886A (ja) | 2001-10-26 | 2009-05-11 | 微細針輸送装置 |
JP2009114991A Pending JP2009219887A (ja) | 2001-10-26 | 2009-05-11 | インピーダンス・センサ |
JP2009114990A Pending JP2009240790A (ja) | 2001-10-26 | 2009-05-11 | 微細針経皮的輸送装置 |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003539742A Pending JP2005525141A (ja) | 2001-10-26 | 2002-10-18 | 微細針輸送装置 |
JP2003539743A Expired - Fee Related JP4612304B2 (ja) | 2001-10-26 | 2002-10-21 | 微細針経皮的輸送装置 |
JP2003539746A Expired - Fee Related JP4610193B2 (ja) | 2001-10-26 | 2002-10-22 | 吸引機構を有する経皮的輸送装置 |
JP2003539745A Pending JP2005507715A (ja) | 2001-10-26 | 2002-10-22 | 電気分解式アクチュエータを有する経皮的輸送装置 |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005304325A Pending JP2006081918A (ja) | 2001-10-26 | 2005-10-19 | 蒸気発生式アクチュエータを有する経皮的輸送装置 |
JP2009114992A Pending JP2009219888A (ja) | 2001-10-26 | 2009-05-11 | 吸引機構を有する経皮的輸送装置 |
JP2009114989A Pending JP2009219886A (ja) | 2001-10-26 | 2009-05-11 | 微細針輸送装置 |
JP2009114991A Pending JP2009219887A (ja) | 2001-10-26 | 2009-05-11 | インピーダンス・センサ |
JP2009114990A Pending JP2009240790A (ja) | 2001-10-26 | 2009-05-11 | 微細針経皮的輸送装置 |
Country Status (8)
Country | Link |
---|---|
US (7) | US7429258B2 (ja) |
EP (5) | EP1439871B1 (ja) |
JP (10) | JP2005525141A (ja) |
AT (3) | ATE420680T1 (ja) |
AU (3) | AU2002353840B2 (ja) |
CA (5) | CA2464483C (ja) |
DE (3) | DE60230896D1 (ja) |
WO (5) | WO2003037403A1 (ja) |
Families Citing this family (396)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6482145B1 (en) | 2000-02-14 | 2002-11-19 | Obtech Medical Ag | Hydraulic anal incontinence treatment |
US6471635B1 (en) | 2000-02-10 | 2002-10-29 | Obtech Medical Ag | Anal incontinence disease treatment with controlled wireless energy supply |
US6464628B1 (en) | 1999-08-12 | 2002-10-15 | Obtech Medical Ag | Mechanical anal incontinence |
US6450173B1 (en) | 1999-08-12 | 2002-09-17 | Obtech Medical Ag | Heartburn and reflux disease treatment with controlled wireless energy supply |
CN1202784C (zh) | 2000-02-10 | 2005-05-25 | 波滕西亚医疗公司 | 控制小便失禁的治疗 |
ATE306233T1 (de) | 2000-02-10 | 2005-10-15 | Potencia Medical Ag | Behandlung der harninkontinenz mit kabelloser energiezufuhr |
ATE391468T1 (de) | 2000-02-10 | 2008-04-15 | Potencia Medical Ag | Mechanische vorrichtung zur impotenzbehandlung |
MX339106B (es) | 2000-02-11 | 2016-05-12 | Potentica Ag | Aparato para tratamiento de impotencia con medio de transformacion de energia. |
BR0108142B1 (pt) * | 2000-02-11 | 2009-01-13 | aparelho para tratamento controlado da impotência. | |
BR0108307B1 (pt) | 2000-02-14 | 2009-12-01 | aparelho de prótese para o tratamento de impotência sexual masculina com dispositivo de suprimento de energia sem fio. | |
US7442165B2 (en) | 2000-02-14 | 2008-10-28 | Obtech Medical Ag | Penile prosthesis |
US20030100929A1 (en) | 2000-02-14 | 2003-05-29 | Peter Forsell | Controlled penile prosthesis |
US7419481B2 (en) * | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
EP1227094B1 (en) * | 2001-01-30 | 2005-12-14 | Nissan Chemical Industries Ltd. | Isocyanurate compound and method for producing the same |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US7041068B2 (en) * | 2001-06-12 | 2006-05-09 | Pelikan Technologies, Inc. | Sampling module device and method |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US6966880B2 (en) * | 2001-10-16 | 2005-11-22 | Agilent Technologies, Inc. | Universal diagnostic platform |
US7429258B2 (en) | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
US7858112B2 (en) * | 2002-02-28 | 2010-12-28 | Lintec Corporation | Percutaneous absorption system and percutaneous absorption method |
US7115108B2 (en) * | 2002-04-02 | 2006-10-03 | Becton, Dickinson And Company | Method and device for intradermally delivering a substance |
US6912417B1 (en) | 2002-04-05 | 2005-06-28 | Ichor Medical Systmes, Inc. | Method and apparatus for delivery of therapeutic agents |
US8784335B2 (en) * | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7713214B2 (en) | 2002-04-19 | 2010-05-11 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US20040039289A1 (en) * | 2002-04-30 | 2004-02-26 | Christensen Lars Hofmann | Needle insertion sensor |
CN1655834A (zh) * | 2002-05-06 | 2005-08-17 | 贝克顿·迪金森公司 | 用于控制药代动力学的方法和装置 |
EP1389476A1 (fr) * | 2002-08-14 | 2004-02-18 | Precimedix S.A. | Dispositif de programmation d'une pompe pour l'injection de medicaments |
WO2004020014A2 (en) * | 2002-08-30 | 2004-03-11 | Becton, Dickinson And Company | Method of controlling pharmacokinetics of immunomodulatory compounds |
US20120296233A9 (en) * | 2002-09-05 | 2012-11-22 | Freeman Dominique M | Methods and apparatus for an analyte detecting device |
WO2004022138A2 (en) | 2002-09-06 | 2004-03-18 | Massachusetts Institute Of Technology | Needless drug injection device |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
MXPA04010963A (es) * | 2003-03-06 | 2005-06-08 | Johnson & Johnson | Sistema y metodo para perforar tejido dermico. |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
CA2529528A1 (en) | 2003-06-20 | 2004-12-29 | Ronald Aung-Din | Topical therapy for the treatment of migraines, muscle sprains, muscle spasm, spasticity and related conditions |
US20050049549A1 (en) * | 2003-08-04 | 2005-03-03 | Wong Patrick S.L. | Method and device for enhancing transdermal agent flux |
EP1671096A4 (en) | 2003-09-29 | 2009-09-16 | Pelikan Technologies Inc | METHOD AND APPARATUS FOR PROVIDING IMPROVED SAMPLE CAPTURING DEVICE |
US9351680B2 (en) | 2003-10-14 | 2016-05-31 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a variable user interface |
EP1527792A1 (en) | 2003-10-27 | 2005-05-04 | Novo Nordisk A/S | Medical injection device mountable to the skin |
US20070191815A1 (en) | 2004-09-13 | 2007-08-16 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
US7097631B2 (en) * | 2003-10-31 | 2006-08-29 | Alza Corporation | Self-actuating applicator for microprojection array |
US7361182B2 (en) | 2003-12-19 | 2008-04-22 | Lightnix, Inc. | Medical lancet |
CN100591265C (zh) | 2003-12-22 | 2010-02-24 | 保罗·哈德瓦里 | 附着皮肤的传感器装置 |
WO2005065765A1 (en) * | 2003-12-29 | 2005-07-21 | 3M Innovative Properties Company | Medical devices and kits including same |
WO2005065414A2 (en) | 2003-12-31 | 2005-07-21 | Pelikan Technologies, Inc. | Method and apparatus for improving fluidic flow and sample capture |
US9364664B2 (en) * | 2004-03-08 | 2016-06-14 | Ichor Medical Systems, Inc. | Apparatus for electrically mediated delivery of therapeutic agents |
EP3251710A1 (en) * | 2004-04-12 | 2017-12-06 | Allergan, Inc. | Multi-site injection system |
WO2005118060A2 (en) * | 2004-04-30 | 2005-12-15 | Boston Scientific Limited | Apparatus with partially insulated needle for measuring tissue impedance and method using same |
US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
US9820684B2 (en) * | 2004-06-03 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US9775553B2 (en) * | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US7872396B2 (en) * | 2004-06-14 | 2011-01-18 | Massachusetts Institute Of Technology | Electrochemical actuator |
US7541715B2 (en) | 2004-06-14 | 2009-06-02 | Massachusetts Institute Of Technology | Electrochemical methods, devices, and structures |
US8247946B2 (en) | 2004-06-14 | 2012-08-21 | Massachusetts Institute Of Technology | Electrochemical actuator |
US7722579B2 (en) | 2004-06-29 | 2010-05-25 | Spine Wave, Inc. | Devices for injecting a curable biomaterial into a intervertebral space |
US20060030811A1 (en) * | 2004-08-03 | 2006-02-09 | Wong Patrick S | Method and device for enhancing transdermal agent flux |
US8696619B2 (en) * | 2004-08-10 | 2014-04-15 | Robert P. Schnall | Drug delivery devices |
EP1786580B1 (en) | 2004-08-16 | 2010-12-01 | Functional Microstructures Limited | Method of producing a microneedle or microimplant |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
EP1827564B1 (en) * | 2004-11-18 | 2015-07-29 | 3M Innovative Properties Company | Masking method for coating a microneedle array |
JP5015787B2 (ja) | 2004-11-18 | 2012-08-29 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイの接触コーティング法 |
US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
JP4927752B2 (ja) | 2004-11-18 | 2012-05-09 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイアプリケーターおよび保持装置 |
EP1833547A1 (en) | 2004-11-18 | 2007-09-19 | 3M Innovative Properties Company | Low-profile microneedle array applicator |
US20080009800A1 (en) * | 2004-12-02 | 2008-01-10 | Nickel Janice H | Transdermal drug delivery device |
CN100367906C (zh) * | 2004-12-08 | 2008-02-13 | 圣美迪诺医疗科技(湖州)有限公司 | 皮下植入式生物传感器 |
US7833189B2 (en) * | 2005-02-11 | 2010-11-16 | Massachusetts Institute Of Technology | Controlled needle-free transport |
US7850645B2 (en) * | 2005-02-11 | 2010-12-14 | Boston Scientific Scimed, Inc. | Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power |
EP1709989A1 (de) * | 2005-04-04 | 2006-10-11 | Christoph Burckhardt AG | Tätowierpistolenspitze |
EP1871459B1 (en) * | 2005-04-07 | 2019-06-19 | 3M Innovative Properties Company | System for tool feedback sensing |
EP1709906A1 (de) * | 2005-04-07 | 2006-10-11 | F. Hoffmann-La Roche Ag | Verfahren und Vorrichtung zur Entnahme von Körperflüssigkeit |
US8298172B2 (en) | 2005-04-13 | 2012-10-30 | Novo Nordisk A/S | Medical skin mountable device and system |
US8372040B2 (en) | 2005-05-24 | 2013-02-12 | Chrono Therapeutics, Inc. | Portable drug delivery device including a detachable and replaceable administration or dosing element |
EP1885341B8 (en) * | 2005-05-24 | 2015-02-18 | Chrono Therapeutics, Inc. | Portable drug delivery device including a detachable and replaceable administration or dosing element |
WO2006128034A1 (en) * | 2005-05-25 | 2006-11-30 | Georgia Tech Research Corporation | Microneedles and methods for microinfusion |
US8021357B2 (en) * | 2005-05-27 | 2011-09-20 | Olympus Corporation | Body-insertable apparatus |
US8505544B2 (en) * | 2005-05-31 | 2013-08-13 | The Board Of Trustees Of The Leland Stanford Junior University | Optically-implemented microsurgery system and approach |
EP1893256B1 (en) | 2005-06-16 | 2012-09-26 | Novo Nordisk A/S | Method and apparatus for assisting patients in self administration of medication |
WO2007002523A2 (en) | 2005-06-24 | 2007-01-04 | 3M Innovative Properties Company | Collapsible patch with microneedle array |
EP2474338B1 (en) | 2005-06-27 | 2013-07-24 | 3M Innovative Properties Company | Microneedle array applicator device |
AU2006264300B2 (en) | 2005-07-06 | 2012-03-08 | Vascular Pathways Inc. | Intravenous catheter insertion device and method of use |
IL175460A (en) | 2006-05-07 | 2011-05-31 | Doron Aurbach | Drug delivery device |
US9687186B2 (en) | 2005-07-21 | 2017-06-27 | Steadymed Ltd. | Drug delivery device |
US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
US8518069B2 (en) | 2005-09-07 | 2013-08-27 | Cabochon Aesthetics, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
US20070185432A1 (en) * | 2005-09-19 | 2007-08-09 | Transport Pharmaceuticals, Inc. | Electrokinetic system and method for delivering methotrexate |
US20070066934A1 (en) * | 2005-09-19 | 2007-03-22 | Transport Pharmaceuticals, Inc. | Electrokinetic delivery system and methods therefor |
JP4935286B2 (ja) * | 2005-10-12 | 2012-05-23 | パナソニック株式会社 | 血液センサ |
CN101291697B (zh) | 2005-10-17 | 2011-05-18 | 诺沃-诺迪斯克有限公司 | 有通气孔的药物贮存单元 |
EP2441486B1 (en) * | 2005-11-02 | 2013-12-11 | Injectica AG | Implantable infusion device |
US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
US7885793B2 (en) | 2007-05-22 | 2011-02-08 | International Business Machines Corporation | Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution |
US9636035B2 (en) * | 2005-12-14 | 2017-05-02 | Scibase Ab | Medical apparatus for determination of biological conditions using impedance measurements |
JP4402648B2 (ja) * | 2005-12-16 | 2010-01-20 | オリンパス株式会社 | 被検体内導入装置 |
US7736310B2 (en) | 2006-01-30 | 2010-06-15 | Abbott Diabetes Care Inc. | On-body medical device securement |
EP1815790A1 (de) * | 2006-02-04 | 2007-08-08 | Roche Diagnostics GmbH | Stechgerät mit Impedanzmesseinrichtung |
CA3213521A1 (en) | 2006-02-09 | 2007-08-16 | Deka Products Limited Partnership | Peripheral systems |
US11318249B2 (en) | 2006-02-09 | 2022-05-03 | Deka Products Limited Partnership | Infusion pump assembly |
ATE532553T1 (de) * | 2006-02-10 | 2011-11-15 | Hisamitsu Pharmaceutical Co | Transdermales arzneiverabreichungsgerät mit mikronadeln |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US7981034B2 (en) | 2006-02-28 | 2011-07-19 | Abbott Diabetes Care Inc. | Smart messages and alerts for an infusion delivery and management system |
EP2319558B1 (en) | 2006-03-14 | 2014-05-21 | University Of Southern California | Mems device for delivery of therapeutic agents |
WO2007124411A1 (en) * | 2006-04-20 | 2007-11-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
US7918814B2 (en) * | 2006-05-02 | 2011-04-05 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
US7621895B2 (en) * | 2006-05-17 | 2009-11-24 | Abbott Cardiovascular Systems Inc. | Needle array devices and methods |
US20070276318A1 (en) * | 2006-05-26 | 2007-11-29 | Mit, Llp | Iontosonic-microneedle applicator apparatus and methods |
US20090171269A1 (en) * | 2006-06-29 | 2009-07-02 | Abbott Diabetes Care, Inc. | Infusion Device and Methods Therefor |
US9119582B2 (en) | 2006-06-30 | 2015-09-01 | Abbott Diabetes Care, Inc. | Integrated analyte sensor and infusion device and methods therefor |
US20090326441A1 (en) * | 2006-08-01 | 2009-12-31 | Agency For Science ,Technology And Research | Ultrasonic Enhanced Microneedles |
US8932216B2 (en) | 2006-08-07 | 2015-01-13 | Abbott Diabetes Care Inc. | Method and system for providing data management in integrated analyte monitoring and infusion system |
US8206296B2 (en) | 2006-08-07 | 2012-06-26 | Abbott Diabetes Care Inc. | Method and system for providing integrated analyte monitoring and infusion system therapy management |
EP2073888A4 (en) * | 2006-08-28 | 2011-01-19 | Agency Science Tech & Res | MICRONED NEEDLES AND METHOD FOR PRODUCING MICRONED NEEDLES |
JP2010502270A (ja) * | 2006-08-29 | 2010-01-28 | アルザ・コーポレーシヨン | 水和可能な貯蔵器の水和測定付きの薬品電気輸送 |
WO2008036043A1 (en) * | 2006-09-18 | 2008-03-27 | Agency For Science, Technology And Research | Needle structures and methods for fabricating needle structures |
AU2007303821B9 (en) | 2006-10-05 | 2013-06-20 | Technion Research & Development Foundation Ltd. | Microtubes and methods of producing same |
JP2010508006A (ja) * | 2006-10-25 | 2010-03-11 | エフ.ホフマン−ラ ロシュ アーゲー | 医療用電気機器用の無停電電力供給装置 |
EP2076172A4 (en) * | 2006-10-27 | 2012-03-21 | Aretais Inc | USE OF COHERENT RAMAN PROCEDURES FOR MEDICAL DIAGNOSTIC AND THERAPEUTIC PURPOSES AND CALIBRATION METHOD THEREFOR |
US10525246B2 (en) * | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
US8845530B2 (en) * | 2007-01-02 | 2014-09-30 | Isense Corporation | Resposable biosensor assembly and method of sensing |
FR2912919B1 (fr) * | 2007-02-22 | 2009-05-01 | Bernard Perriere | Dispositif d'injection miniaturise a usage medical |
US20080249469A1 (en) * | 2007-03-22 | 2008-10-09 | Ponnambalam Selvaganapathy | Method and apparatus for active control of drug delivery using electro-osmotic flow control |
WO2008130587A2 (en) | 2007-04-16 | 2008-10-30 | Corium International, Inc. | Solvent-cast microneedle arrays containing active |
GB2448493B (en) * | 2007-04-16 | 2009-10-14 | Dewan Fazlul Hoque Chowdhury | Microneedle transdermal delivery device |
ATE489989T1 (de) | 2007-05-07 | 2010-12-15 | Vascular Pathways Inc | Einführung eines intravenösen katheters und blutentnahmevorrichtung und anwendungsverfahren |
US20090069830A1 (en) * | 2007-06-07 | 2009-03-12 | Piezo Resonance Innovations, Inc. | Eye surgical tool |
KR101500022B1 (ko) * | 2007-06-21 | 2015-03-06 | 가부시키가이샤 후지모토 코포레이션 | 경피 또는 경점막 투여용 조성물 |
US8641618B2 (en) | 2007-06-27 | 2014-02-04 | Abbott Diabetes Care Inc. | Method and structure for securing a monitoring device element |
US8085151B2 (en) | 2007-06-28 | 2011-12-27 | Abbott Diabetes Care Inc. | Signal converting cradle for medical condition monitoring and management system |
US10219832B2 (en) | 2007-06-29 | 2019-03-05 | Actuated Medical, Inc. | Device and method for less forceful tissue puncture |
US8328738B2 (en) | 2007-06-29 | 2012-12-11 | Actuated Medical, Inc. | Medical tool for reduced penetration force with feedback means |
US9987468B2 (en) | 2007-06-29 | 2018-06-05 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US8043229B2 (en) * | 2007-06-29 | 2011-10-25 | Actuated Medical, Inc. | Medical tool for reduced penetration force |
US8160900B2 (en) | 2007-06-29 | 2012-04-17 | Abbott Diabetes Care Inc. | Analyte monitoring and management device and method to analyze the frequency of user interaction with the device |
WO2009015389A2 (en) * | 2007-07-26 | 2009-01-29 | Entra Pharmaceuticals Inc. | Skin-patch pump comprising a changing-volume electrochemical actuator |
EP2178585B1 (en) * | 2007-08-14 | 2021-04-07 | Fred Hutchinson Cancer Research Center | Needle array assembly and method for delivering therapeutic agents |
US11154698B2 (en) * | 2007-08-24 | 2021-10-26 | Deka Products Limited Partnership | Microneedle systems and apparatus |
WO2009029044A1 (en) * | 2007-08-24 | 2009-03-05 | Agency For Science, Technology And Research | A system and method for detecting skin penetration |
US9096845B2 (en) * | 2007-08-29 | 2015-08-04 | Technion Research & Development Foundation Limited | Encapsulation of bacteria and viruses in electrospun fibers |
US20090088682A1 (en) * | 2007-09-28 | 2009-04-02 | Seattle Medical Technologies | Wearable infusion device |
US8439940B2 (en) | 2010-12-22 | 2013-05-14 | Cabochon Aesthetics, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
CN101970030B (zh) * | 2007-12-17 | 2014-04-16 | 新世界药品有限公司 | 整合的真皮内递送、诊断和通讯系统 |
EP2666510B1 (en) | 2007-12-20 | 2017-10-18 | University Of Southern California | Apparatus for controlled delivery of therapeutic agents |
FI20075978A0 (fi) * | 2007-12-31 | 2007-12-31 | Katja Paassilta | Järjestely ja menetelmä |
EP2244765B1 (en) | 2007-12-31 | 2019-08-14 | DEKA Products Limited Partnership | Infusion pump assembly |
BR122020005551B1 (pt) | 2007-12-31 | 2021-08-10 | Deka Products Limited Partnership | Conjunto de bomba de infusão |
US11357910B2 (en) | 2007-12-31 | 2022-06-14 | Deka Products Limited Partnership | Pump assembly with switch |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
EP2244760B8 (en) * | 2008-01-28 | 2022-07-20 | Implantica Patent Ltd. | An implantable drainage device |
US9877859B2 (en) | 2008-01-29 | 2018-01-30 | Peter Forsell | Methods and instruments for treating obesity and gastroesophageal reflux disease |
WO2009104174A2 (en) * | 2008-02-21 | 2009-08-27 | Technion Research & Development Foundation Ltd . | A method of attaching a cell-of-interest to a microtube |
WO2009108836A1 (en) * | 2008-02-29 | 2009-09-03 | Path Scientific, Llc | Unitized painfree blood glucose measuring device |
JP2009222474A (ja) * | 2008-03-14 | 2009-10-01 | Panasonic Corp | 微量液体供給装置および微量液体供給方法 |
WO2009137785A2 (en) | 2008-05-08 | 2009-11-12 | Replenish Pumps, Llc | Drug-delivery pumps and methods of manufacture |
JP5719767B2 (ja) | 2008-05-08 | 2015-05-20 | ミニパンプス, エルエルシー | 埋込型ポンプおよびそのためのカニューレ |
US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
US9381680B2 (en) | 2008-05-21 | 2016-07-05 | Theraject, Inc. | Method of manufacturing solid solution perforator patches and uses thereof |
US8924159B2 (en) | 2008-05-30 | 2014-12-30 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
US8591410B2 (en) | 2008-05-30 | 2013-11-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
CA2729346A1 (en) | 2008-06-30 | 2010-01-14 | Afgin Pharma, Llc | Topical regional neuro-affective therapy |
WO2010004721A1 (ja) * | 2008-07-08 | 2010-01-14 | パナソニック株式会社 | 導電性高分子を用いた流体搬送装置 |
US8868176B2 (en) * | 2008-07-22 | 2014-10-21 | New York University | Microelectrode-equipped subdural therapeutic agent delivery strip |
WO2010023666A2 (en) * | 2008-08-28 | 2010-03-04 | Medingo Ltd. | Device and method for enhanced subcutaneous insulin absorption |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
AU2009293019A1 (en) | 2008-09-19 | 2010-03-25 | Tandem Diabetes Care Inc. | Solute concentration measurement device and related methods |
WO2010042011A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding Sa | Heart help device, system, and method |
WO2010042014A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding Sa | Heart help device, system, and method |
US10219898B2 (en) | 2008-10-10 | 2019-03-05 | Peter Forsell | Artificial valve |
US8874215B2 (en) | 2008-10-10 | 2014-10-28 | Peter Forsell | System, an apparatus, and a method for treating a sexual dysfunctional female patient |
WO2010042032A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding S.A. | Fastening means for implantable medcial control assembly |
ES2962384T3 (es) | 2008-10-10 | 2024-03-18 | Implantica Patent Ltd | Aparato para el tratamiento de la disfunción sexual femenina |
WO2010052692A1 (en) * | 2008-11-04 | 2010-05-14 | Janisys Limited | A transfer device for transferring a substance between the device and a subject |
SI2384210T1 (en) | 2008-12-02 | 2018-02-28 | Allergan, Inc. | Injection device |
US20110301628A1 (en) * | 2008-12-05 | 2011-12-08 | Yossi Gross | Techniques for use with a nail penetration device |
WO2010070628A1 (en) * | 2008-12-19 | 2010-06-24 | Janisys Limited | A fluid transfer device and an active substance cartridge for the fluid transfer device, and a method for controlling the pressure at which an active substance is delivered to a subject from a fluid transfer device |
US20100187132A1 (en) * | 2008-12-29 | 2010-07-29 | Don Alden | Determination of the real electrochemical surface areas of screen printed electrodes |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
EP3566649B1 (en) | 2009-03-02 | 2023-06-07 | YourBio Health, Inc. | Devices for blood sampling |
US9119578B2 (en) | 2011-04-29 | 2015-09-01 | Seventh Sense Biosystems, Inc. | Plasma or serum production and removal of fluids under reduced pressure |
US20110105951A1 (en) * | 2009-10-30 | 2011-05-05 | Seventh Sense Biosystems, Inc. | Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin |
US8781576B2 (en) * | 2009-03-17 | 2014-07-15 | Cardiothrive, Inc. | Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current |
CN102427851B (zh) | 2009-03-17 | 2015-04-15 | 卡迪欧思莱夫公司 | 体外除颤器 |
DE102009002019A1 (de) * | 2009-03-31 | 2010-10-07 | Robert Bosch Gmbh | Applikator zur Behandlung von Haut |
EP2425209A4 (en) | 2009-04-29 | 2013-01-09 | Abbott Diabetes Care Inc | METHOD AND SYSTEM FOR REAL-TIME CALIBRATION OF AN ANALYTICAL SENSOR WITH RETROACTIVE FILLING |
US20120130207A1 (en) * | 2009-04-29 | 2012-05-24 | Janisys Limited | micro-needle device and apparatus and a method for applying a micro-needle element to a site on the skin of a subject |
EP2432525A1 (en) * | 2009-05-20 | 2012-03-28 | Sanofi-Aventis Deutschland GmbH | Drug delivery device |
US10952836B2 (en) | 2009-07-17 | 2021-03-23 | Peter Forsell | Vaginal operation method for the treatment of urinary incontinence in women |
US9949812B2 (en) | 2009-07-17 | 2018-04-24 | Peter Forsell | Vaginal operation method for the treatment of anal incontinence in women |
US8758323B2 (en) | 2009-07-30 | 2014-06-24 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
AU2010276511B2 (en) | 2009-07-31 | 2013-09-19 | Kindeva Drug Delivery L.P. | Hollow microneedle arrays |
US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
JP5758388B2 (ja) | 2009-08-18 | 2015-08-05 | ミニパンプス, エルエルシー | 適応制御を有する電解質薬物送達ポンプ |
WO2011028719A2 (en) | 2009-09-01 | 2011-03-10 | Massachusetts Institute Of Technology | Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties |
US20110060202A1 (en) * | 2009-09-08 | 2011-03-10 | Seth Adrian Miller | Dehydration detector using micro-needles |
DK2475408T3 (en) * | 2009-09-10 | 2015-05-26 | Sanofi Aventis Deutschland | Drug container |
US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
US8685038B2 (en) | 2009-12-07 | 2014-04-01 | Incube Labs, Llc | Iontophoretic apparatus and method for marking of the skin |
WO2011075535A1 (en) | 2009-12-15 | 2011-06-23 | Massachusetts Institute Of Technology | Plaque removal and differentiation of tooth and gum |
US20110172637A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Drug delivery device including tissue support structure |
CN107115115B (zh) * | 2010-01-13 | 2021-03-30 | 第七感生物系统有限公司 | 输送和/或抽出流体的装置 |
EP2523603A2 (en) * | 2010-01-13 | 2012-11-21 | Seventh Sense Biosystems, Inc. | Sampling device interfaces |
WO2011088214A2 (en) * | 2010-01-13 | 2011-07-21 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or withdrawal of fluids |
WO2011094573A1 (en) | 2010-01-28 | 2011-08-04 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
US8366667B2 (en) * | 2010-02-11 | 2013-02-05 | Baxter International Inc. | Flow pulsatility dampening devices |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US20120041427A1 (en) | 2010-04-20 | 2012-02-16 | Minipumps, Llc | Electrolytically driven drug pump devices |
CN102958556B (zh) | 2010-04-28 | 2017-02-15 | 金伯利-克拉克环球有限公司 | 细胞相互作用增强的纳米图案化医疗装置 |
CN102985131B (zh) | 2010-04-28 | 2016-06-29 | 金伯利-克拉克环球有限公司 | 用于递送siRNA的医疗装置 |
US9629979B2 (en) * | 2010-04-28 | 2017-04-25 | Sanovas, Inc. | Pressure/Vacuum actuated catheter drug delivery probe |
WO2012046149A1 (en) | 2010-04-28 | 2012-04-12 | Kimberly-Clark Worldwide, Inc. | Method for increasing permeability of an epithelial barrier |
CN102971037B (zh) | 2010-04-28 | 2016-05-25 | 金伯利-克拉克环球有限公司 | 用于递送类风湿性关节炎药物的装置 |
US9687641B2 (en) | 2010-05-04 | 2017-06-27 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
WO2011140359A2 (en) * | 2010-05-05 | 2011-11-10 | Springleaf Therapeutics, Inc. | Systems and methods for delivering a therapeutic agent |
US8932258B2 (en) | 2010-05-14 | 2015-01-13 | C. R. Bard, Inc. | Catheter placement device and method |
US10384039B2 (en) | 2010-05-14 | 2019-08-20 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
US9950139B2 (en) | 2010-05-14 | 2018-04-24 | C. R. Bard, Inc. | Catheter placement device including guidewire and catheter control elements |
US9872971B2 (en) | 2010-05-14 | 2018-01-23 | C. R. Bard, Inc. | Guidewire extension system for a catheter placement device |
US11925779B2 (en) | 2010-05-14 | 2024-03-12 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
WO2011156095A2 (en) | 2010-06-10 | 2011-12-15 | The Regents Of The University Of California | Textile-based printable electrodes for electrochemical sensing |
WO2011163347A2 (en) | 2010-06-23 | 2011-12-29 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
US9227021B2 (en) | 2010-06-29 | 2016-01-05 | Genesis Biosystems, Inc. | Microneedle roller (MNR) infusion system |
JP2013538069A (ja) | 2010-07-16 | 2013-10-10 | セブンス センス バイオシステムズ,インコーポレーテッド | 流体移動デバイスのための低圧環境 |
US20130158482A1 (en) | 2010-07-26 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
US8814792B2 (en) | 2010-07-27 | 2014-08-26 | Carefusion 303, Inc. | System and method for storing and forwarding data from a vital-signs monitor |
US9357929B2 (en) | 2010-07-27 | 2016-06-07 | Carefusion 303, Inc. | System and method for monitoring body temperature of a person |
US9420952B2 (en) | 2010-07-27 | 2016-08-23 | Carefusion 303, Inc. | Temperature probe suitable for axillary reading |
US9055925B2 (en) | 2010-07-27 | 2015-06-16 | Carefusion 303, Inc. | System and method for reducing false alarms associated with vital-signs monitoring |
US9017255B2 (en) | 2010-07-27 | 2015-04-28 | Carefusion 303, Inc. | System and method for saving battery power in a patient monitoring system |
US9585620B2 (en) | 2010-07-27 | 2017-03-07 | Carefusion 303, Inc. | Vital-signs patch having a flexible attachment to electrodes |
US9615792B2 (en) | 2010-07-27 | 2017-04-11 | Carefusion 303, Inc. | System and method for conserving battery power in a patient monitoring system |
DE102010038733A1 (de) | 2010-07-30 | 2012-02-02 | Robert Bosch Gmbh | Modulare Mikronadel-Transportvorrichtung |
US20120039809A1 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
US9173994B2 (en) * | 2010-08-20 | 2015-11-03 | Purdue Research Foundation | Touch-actuated micropump for transdermal drug delivery and method of use |
ES2701019T3 (es) * | 2010-09-27 | 2019-02-20 | Steadymed Ltd | Dispositivo de administración de fármacos con un tamaño eficiente |
US8821434B2 (en) | 2010-10-07 | 2014-09-02 | Massachusetts Institute Of Technology | Delivery of a solid body and/or a fluid using a linear Lorentz-force actuated needle-free jet injection system |
EP2915552A1 (en) | 2010-10-07 | 2015-09-09 | Massachusetts Institute of Technology | Injection methods using a servo-controlled needle-free injector |
JP5996544B2 (ja) | 2010-10-15 | 2016-09-21 | クリアサイド・バイオメディカル・インコーポレーテッドClearside Biomedical Incorporated | 眼球アクセス用装置 |
WO2012058192A1 (en) * | 2010-10-26 | 2012-05-03 | 7944942 Canada Inc. | Automatic medication injection device |
US9017289B2 (en) | 2010-11-03 | 2015-04-28 | Covidien Lp | Transdermal fluid delivery device |
US8808202B2 (en) | 2010-11-09 | 2014-08-19 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
US8368285B2 (en) | 2010-12-17 | 2013-02-05 | Massachusette Institute Of Technology | Electrochemical actuators |
US8690833B2 (en) | 2011-01-31 | 2014-04-08 | Vascular Pathways, Inc. | Intravenous catheter and insertion device with reduced blood spatter |
CA2826822C (en) | 2011-02-09 | 2018-10-02 | Gary Searle | Improvements in infusion systems |
EP2678065B1 (en) | 2011-02-25 | 2019-09-11 | C.R. Bard Inc. | Medical component insertion device including a retractable needle |
US8696637B2 (en) | 2011-02-28 | 2014-04-15 | Kimberly-Clark Worldwide | Transdermal patch containing microneedles |
US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
WO2012139593A2 (en) * | 2011-04-15 | 2012-10-18 | Rigshospitalet Copenhagen University Hospital | System and method for injecting a substance into a human body |
AU2012245372A1 (en) * | 2011-04-19 | 2013-11-14 | Invisiderm, Llc | Method of producing substances with supersaturated gas,transdermal delivery device thereof, and uses thereof |
BR112013027010A2 (pt) * | 2011-04-19 | 2016-12-27 | Invisiderm Llc | método de produzir substâncias com gás supersaturado, dispositivo para sua entrega trasdérmica, e seus usos |
US20130158468A1 (en) * | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
KR102237667B1 (ko) * | 2011-04-29 | 2021-04-12 | 세븐쓰 센스 바이오시스템즈, 인크. | 유체들의 전달 및/또는 수용 |
WO2012149155A1 (en) | 2011-04-29 | 2012-11-01 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
USD903101S1 (en) | 2011-05-13 | 2020-11-24 | C. R. Bard, Inc. | Catheter |
US8636696B2 (en) | 2011-06-10 | 2014-01-28 | Kimberly-Clark Worldwide, Inc. | Transdermal device containing microneedles |
WO2013006643A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
KR101542549B1 (ko) | 2011-09-02 | 2015-08-06 | 산디아 코포레이션 | 바이오센싱 및 약물 전달을 위한 마이크로니들 어레이 |
US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
CN103906549A (zh) | 2011-10-27 | 2014-07-02 | 金伯利-克拉克环球有限公司 | 用于递送生物活性剂的可植入装置 |
RU2630610C2 (ru) | 2011-10-27 | 2017-09-11 | Кимберли-Кларк Ворлдвайд, Инк. | Трансдермальная доставка высоковязких биоактивных агентов |
EP2771043A4 (en) | 2011-10-28 | 2015-04-29 | Presage Biosciences Inc | METHODS OF DRUG DELIVERY |
US9317656B2 (en) | 2011-11-23 | 2016-04-19 | Abbott Diabetes Care Inc. | Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof |
DE12858350T1 (de) | 2011-12-16 | 2021-10-07 | Modernatx, Inc. | Modifizierte mrna zusammensetzungen |
DE102011089723A1 (de) * | 2011-12-23 | 2013-06-27 | Robert Bosch Gmbh | Mikronadelarray-Applikator und Verfahren zur Applikation eines Mikronadelarrays |
US10130800B2 (en) | 2012-01-27 | 2018-11-20 | Invisiderm, Llc | Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof |
EP2825106B1 (en) | 2012-03-13 | 2019-05-08 | Becton Dickinson France | Injection device having a miniaturized drug delivery portion |
WO2013136327A1 (en) | 2012-03-15 | 2013-09-19 | Steadymed Ltd. | Enhanced infusion-site pain-reduction for drug-delivery devices |
US9724462B2 (en) | 2012-03-19 | 2017-08-08 | Steadymed Ltd. | Fluid-connection mechanism for patch-pumps |
KR20130114996A (ko) * | 2012-04-10 | 2013-10-21 | 삼성디스플레이 주식회사 | 표시 장치 및 그 제조방법 |
CN104703651A (zh) | 2012-05-01 | 2015-06-10 | 高等教育联邦系统-匹兹堡大学 | 用于经皮插入的尖端负载的微针阵列 |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
US20150173991A1 (en) * | 2012-07-06 | 2015-06-25 | The General Hospital Corporation | Method and apparatus for dermatological treatment |
WO2019135244A2 (en) * | 2018-01-07 | 2019-07-11 | Avraham Amir | High-load microneedles and compositions for skin augmentation |
US9782538B2 (en) | 2012-09-27 | 2017-10-10 | Becton, Dickinson And Company | Angled inserter for drug infusion |
MX2015005839A (es) | 2012-11-08 | 2015-12-17 | Clearside Biomedical Inc | Metodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos. |
US9597380B2 (en) | 2012-11-26 | 2017-03-21 | Modernatx, Inc. | Terminally modified RNA |
MX2015008157A (es) | 2012-12-21 | 2016-02-22 | Corium Int Inc | Microarreglo para la entrega de agente terapeutico y metodos de uso. |
EP2946014A2 (en) | 2013-01-17 | 2015-11-25 | Moderna Therapeutics, Inc. | Signal-sensor polynucleotides for the alteration of cellular phenotypes |
US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
WO2014120741A1 (en) | 2013-01-30 | 2014-08-07 | Vascular Pathways, Inc. | Systems and methods for venipuncture and catheter placement |
KR102370538B1 (ko) * | 2013-02-28 | 2022-03-07 | 소렌토 쎄라퓨틱스, 인코포레이티드 | 경피 약물 전달 장치 |
BR112015022253B1 (pt) | 2013-03-12 | 2022-03-15 | Corium, Inc | Aplicador de microprojeções |
WO2014159813A1 (en) | 2013-03-13 | 2014-10-02 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
US10080839B2 (en) | 2013-03-14 | 2018-09-25 | Becton, Dickinson And Company | Angled inserter for drug infusion |
JP6098250B2 (ja) * | 2013-03-14 | 2017-03-22 | セイコーエプソン株式会社 | 液体輸送装置 |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
AU2014237279B2 (en) | 2013-03-15 | 2018-11-22 | Corium Pharma Solutions, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
US9821113B2 (en) | 2013-03-15 | 2017-11-21 | Becton, Dickinson And Company | Automatic angled infusion set assembly |
BR112015022625B1 (pt) | 2013-03-15 | 2023-01-31 | Corium, Inc | Aparelho de microestrutura para entrega de agente terapêutico |
CA2903459C (en) * | 2013-03-15 | 2024-02-20 | Corium International, Inc. | Multiple impact microprojection applicators and methods of use |
EP2968736A4 (en) * | 2013-03-15 | 2016-11-09 | Amgen Inc | ADJUSTABLE TO A BODY SHAPE AUTO INJECTOR DEVICE |
US9603995B2 (en) | 2013-03-15 | 2017-03-28 | Tandem Diabetes Care. Inc. | Device and method for setting therapeutic parameters for an infusion device |
CN110302004B (zh) | 2013-05-03 | 2023-04-28 | 科尼尔赛德生物医学公司 | 用于眼部注射的设备和方法 |
US20140350518A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Syringe extrusion accessory |
US20140350516A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Mechanical syringe accessory |
EP3003454B1 (en) | 2013-06-03 | 2020-01-08 | Clearside Biomedical, Inc. | Apparatus for drug delivery using multiple reservoirs |
US9833630B2 (en) | 2013-06-14 | 2017-12-05 | Cardiothrive, Inc. | Biphasic or multiphasic pulse waveform and method |
US10149973B2 (en) | 2013-06-14 | 2018-12-11 | Cardiothrive, Inc. | Multipart non-uniform patient contact interface and method of use |
US9616243B2 (en) | 2013-06-14 | 2017-04-11 | Cardiothrive, Inc. | Dynamically adjustable multiphasic defibrillator pulse system and method |
US9656094B2 (en) | 2013-06-14 | 2017-05-23 | Cardiothrive, Inc. | Biphasic or multiphasic pulse generator and method |
US10279189B2 (en) | 2013-06-14 | 2019-05-07 | Cardiothrive, Inc. | Wearable multiphasic cardioverter defibrillator system and method |
US9907970B2 (en) | 2013-06-14 | 2018-03-06 | Cardiothrive, Inc. | Therapeutic system and method using biphasic or multiphasic pulse waveform |
CN105324147B (zh) * | 2013-06-18 | 2018-03-02 | 久光制药株式会社 | 施放器 |
ES2753423T3 (es) | 2013-06-19 | 2020-04-08 | Hisamitsu Pharmaceutical Co | Aplicador |
US20150027241A1 (en) * | 2013-07-23 | 2015-01-29 | Diba Industries, Inc. | Piercing probes with offset conical piercing tip and fluid-sampling systems comprising the piercing probes |
US10299793B2 (en) | 2013-10-23 | 2019-05-28 | Valtech Cardio, Ltd. | Anchor magazine |
WO2015095351A1 (en) | 2013-12-19 | 2015-06-25 | Novartis Ag | LEPTIN mRNA COMPOSITIONS AND FORMULATIONS |
WO2015119906A1 (en) | 2014-02-05 | 2015-08-13 | Amgen Inc. | Drug delivery system with electromagnetic field generator |
GB201403773D0 (en) * | 2014-03-04 | 2014-04-16 | Univ Cardiff | Microneedle based cell delivery |
US10279106B1 (en) | 2014-05-08 | 2019-05-07 | Tandem Diabetes Care, Inc. | Insulin patch pump |
US10029048B2 (en) | 2014-05-13 | 2018-07-24 | Allergan, Inc. | High force injection devices |
CN112237662B (zh) | 2014-06-03 | 2022-10-21 | 安姆根有限公司 | 药物递送系统和使用方法 |
MX2016017028A (es) | 2014-06-20 | 2017-08-07 | Clearside Biomedical Inc | Canula de diametro variable y metodos para el control de la profundidad de insercion para administracion de medicamentos. |
US10321858B2 (en) | 2014-08-18 | 2019-06-18 | Proteadx, Inc. | Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems |
WO2016036866A1 (en) | 2014-09-04 | 2016-03-10 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
WO2016037127A1 (en) | 2014-09-05 | 2016-03-10 | C.R. Bard, Inc. | Catheter insertion device including retractable needle |
US10485925B2 (en) * | 2014-09-15 | 2019-11-26 | Sanofi | Medicament delivery device with rotatable housing on a base |
DE102014219719B4 (de) * | 2014-09-29 | 2018-05-03 | Ipr Intelligente Peripherien Für Roboter Gmbh | Nadelgreifer |
US10226585B2 (en) | 2014-10-01 | 2019-03-12 | Allergan, Inc. | Devices for injection and dosing |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
ES2894735T3 (es) * | 2014-10-27 | 2022-02-15 | Glutalor Medical Inc | Aparatos de recolección continua de glucosa |
JP6716566B2 (ja) | 2014-12-19 | 2020-07-01 | アムジエン・インコーポレーテツド | 近接センサ付き薬物送達装置 |
ES2785311T3 (es) | 2014-12-19 | 2020-10-06 | Amgen Inc | Dispositivo de administración de fármacos con botón móvil o campo de interfaz de usuario |
WO2016105478A1 (en) | 2014-12-23 | 2016-06-30 | Axell Wireless Ltd. | Harmonizing noise aggregation and noise management in distributed antenna system |
EP3045185A1 (en) * | 2015-01-16 | 2016-07-20 | Sanofi-Aventis Deutschland GmbH | Connector for a container filled with a liquid medicament |
AU2016211330A1 (en) | 2015-01-28 | 2017-08-03 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
CA2976935C (en) * | 2015-02-17 | 2020-03-10 | Amgen Inc. | Drug delivery device with vacuum assisted securement and/or feedback |
EP3268063A4 (en) | 2015-03-10 | 2018-10-31 | Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company | Multiple needle injector |
AU2016228779A1 (en) | 2015-03-12 | 2017-09-07 | Chrono Therapeutics Inc. | Craving input and support system |
US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
USD903100S1 (en) | 2015-05-01 | 2020-11-24 | C. R. Bard, Inc. | Catheter placement device |
JP6784352B2 (ja) * | 2015-05-11 | 2020-11-11 | 国立大学法人 東京医科歯科大学 | インスリン送達用デバイス |
ES2910665T3 (es) | 2015-05-15 | 2022-05-13 | Bard Inc C R | Dispositivo de inserción de catéter |
US10463847B2 (en) | 2015-06-11 | 2019-11-05 | Steadymed Ltd. | Infusion set |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
US10940292B2 (en) | 2015-07-08 | 2021-03-09 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US11793543B2 (en) | 2015-09-18 | 2023-10-24 | Obvius Robotics, Inc. | Device and method for automated insertion of penetrating member |
US11684763B2 (en) | 2015-10-16 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices |
WO2017120322A1 (en) | 2016-01-05 | 2017-07-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
WO2017139375A1 (en) | 2016-02-10 | 2017-08-17 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
EP3416621B1 (en) * | 2016-02-19 | 2023-12-20 | North Carolina State University | Physiologically responsive microneedle delivery systems |
CA3018223A1 (en) | 2016-03-28 | 2017-10-05 | Ichor Medical Systems, Inc. | Method and apparatus for delivery of therapeutic agents |
BR112018070642A2 (pt) | 2016-04-08 | 2019-02-05 | Allergan Inc | dispositivo de aspiração e injeção |
CA3062845A1 (en) | 2016-05-02 | 2017-11-09 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
US20200306518A1 (en) * | 2016-05-20 | 2020-10-01 | Uprax Microsolutions B.V. | System and method for applying microneedles |
NL2016807B1 (en) * | 2016-05-20 | 2017-11-27 | Uprax | System and method for applying microneedles |
US10220195B2 (en) * | 2016-06-08 | 2019-03-05 | Eclipse Medcorp, Llc | Radio frequency needling device for use with disposable needle cartridges |
US10973681B2 (en) | 2016-08-12 | 2021-04-13 | Clearside Biomedical, Inc. | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
CA3034478A1 (en) | 2016-09-12 | 2018-03-15 | C.R. Bard, Inc. | Blood control for a catheter insertion device |
US11241563B2 (en) | 2016-12-22 | 2022-02-08 | Johnson & Johnson Consumer Inc. | Microneedle arrays and methods for making and using |
EP3338832A1 (en) * | 2016-12-23 | 2018-06-27 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device |
JP2020503950A (ja) | 2017-01-06 | 2020-02-06 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | 経皮薬剤送達の装置及び方法 |
JP6953541B2 (ja) | 2017-03-01 | 2021-10-27 | シー・アール・バード・インコーポレーテッドC R Bard Incorporated | カテーテル挿入装置 |
USD867582S1 (en) | 2017-03-24 | 2019-11-19 | Allergan, Inc. | Syringe device |
AU2018251786B2 (en) | 2017-04-13 | 2020-08-27 | Teleflex Medical Incorporated | Catheter insertion device |
US11045142B1 (en) | 2017-04-29 | 2021-06-29 | Biolinq, Inc. | Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry |
CN109833562B (zh) * | 2017-11-27 | 2024-03-15 | 苏州纳通生物纳米技术有限公司 | 一种一次性自毁式振动头组件以及应用该组件的促渗仪 |
US10828500B2 (en) | 2017-12-22 | 2020-11-10 | Cardiothrive, Inc. | External defibrillator |
EP3762084B1 (en) | 2018-03-07 | 2024-04-24 | Bard Access Systems, Inc. | Guidewire advancement and blood flashback systems for a medical device insertion system |
US11090506B2 (en) * | 2018-05-15 | 2021-08-17 | Omm Imports, Inc. | Disposable product cap and assembly having a manually usable thermo-optical device for skin care |
JP7420797B2 (ja) | 2018-05-29 | 2024-01-23 | モーニングサイド ベンチャー インベストメンツ リミテッド | 薬剤送達の方法及びシステム |
US11413440B2 (en) * | 2018-06-29 | 2022-08-16 | Johnson & Johnson Consumer Inc. | Three-dimensional microfluidics devices for the delivery of actives |
USD921884S1 (en) | 2018-07-27 | 2021-06-08 | Bard Access Systems, Inc. | Catheter insertion device |
FR3084578B1 (fr) * | 2018-08-03 | 2024-01-12 | Pkvitality | Gestion enfoncement de microaiguilles |
CN113646023B (zh) | 2019-02-22 | 2023-07-21 | 德卡产品有限公司 | 输液器以及插入物组件系统和方法 |
WO2020188484A1 (en) * | 2019-03-19 | 2020-09-24 | King Abdullah University Of Science And Technology | Miniaturized delivery system and method |
US11590332B2 (en) * | 2019-04-17 | 2023-02-28 | Path Scientific, Llc | Precision microneedling device and methods of use |
GB201908043D0 (en) * | 2019-06-05 | 2019-07-17 | Lekkos Vasileios | Transdermal patch for therapeutic uses |
KR102279603B1 (ko) * | 2019-06-11 | 2021-07-20 | (주)비올 | 바늘 조립체, 이를 포함하는 피부 자극기 및 그 제조 방법 |
EP3997452A4 (en) * | 2019-07-12 | 2023-08-16 | Qulab Medical Ltd. | ELECTROCHEMICAL FET SENSOR |
WO2021020730A2 (ko) * | 2019-07-26 | 2021-02-04 | 주식회사 림사이언스 | 의료용 니들을 가압하는 장치 |
JP2022545447A (ja) | 2019-08-19 | 2022-10-27 | ベクトン・ディキンソン・アンド・カンパニー | 正中線カテーテル配置デバイス |
EP4051337A4 (en) * | 2019-10-30 | 2023-11-01 | Thermalin Inc. | DRUG RELEASE SYSTEMS, DEVICES AND METHODS |
US20230191099A1 (en) * | 2020-02-20 | 2023-06-22 | Jubilee Biotech Co., Ltd. | Applicator for drug delivery and microneedle patch used therefor |
US20220031244A1 (en) | 2020-07-29 | 2022-02-03 | Biolinq Inc. | Continuous analyte monitoring system with microneedle array |
CN112370653B (zh) * | 2020-11-12 | 2022-08-30 | 深圳市圣通生物科技有限公司 | 一种喷淋消毒式纳米微针中胚层导入美容仪 |
WO2022187821A1 (en) * | 2021-03-01 | 2022-09-09 | Bluexthermal, Inc. | Device and method for thermal modulation of tissue |
US11964121B2 (en) | 2021-10-13 | 2024-04-23 | Satio, Inc. | Mono dose dermal patch for pharmaceutical delivery |
US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
US11510602B1 (en) | 2021-11-08 | 2022-11-29 | Satio, Inc. | Dermal patch for collecting a physiological sample |
US11452474B1 (en) | 2021-04-14 | 2022-09-27 | Satio, Inc. | Dual lever dermal patch system |
US12023156B2 (en) | 2021-10-13 | 2024-07-02 | Satio, Inc. | Dermal patch for collecting a physiological sample |
SE545874C2 (en) | 2021-05-08 | 2024-02-27 | Biolinq Incorporated | Fault detection for microneedle array based continuous analyte monitoring device |
EP4295873A1 (en) * | 2022-06-21 | 2023-12-27 | National University of Ireland Galway | An infusion catheter system |
Family Cites Families (144)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US447225A (en) * | 1891-02-24 | Machine for attaching stays to the corners of boxes | ||
US3659A (en) * | 1844-07-11 | Machine for hulling and pearling rice | ||
US3537A (en) | 1844-04-13 | X g gupping instrument | ||
US1934043A (en) | 1929-05-17 | 1933-11-07 | Standard Oil Dev Co | Process of improvement of lubricating oils |
DE596981C (de) | 1931-10-30 | 1934-05-12 | Mario Demarchi Dr | Injektionsspritze |
FR757501A (fr) | 1932-09-23 | 1933-12-28 | Dispositif automatique pour la manceuvre des seringues d'injection | |
US2088780A (en) | 1936-10-09 | 1937-08-03 | Sigurd E Follese | Massage device |
US2763935A (en) | 1954-06-11 | 1956-09-25 | Purdne Res Foundation | Determining depth of layers of fat and of muscle on an animal body |
US2945496A (en) | 1958-08-18 | 1960-07-19 | Fosdal Alfred | Dental instrument for immobilizing tissue |
DE1115722B (de) | 1960-04-30 | 1961-10-26 | Hoechst Ag | Metallanode fuer die elektrolytische Abscheidung von Chlor |
GB1128329A (en) | 1964-12-23 | 1968-09-25 | Nat Res Dev | Electrodes for making electrical contact to the living body of a mammal |
US3568735A (en) * | 1968-06-26 | 1971-03-09 | Cooke Eng Co | Laboratory microtitration dispensing apparatus |
US3568732A (en) | 1969-02-28 | 1971-03-09 | Kelly James A Jun | Splice straightener for aerial conductors |
US3659600A (en) | 1970-02-24 | 1972-05-02 | Estin Hans H | Magnetically operated capsule for administering drugs |
US3727614A (en) | 1971-05-13 | 1973-04-17 | Merck & Co Inc | Multiple dosage inoculator |
US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3738493A (en) | 1971-09-24 | 1973-06-12 | Analytical Instr Spec | Apparatus for simultaneous application of samples to thin layer chromatography plates |
BE795384A (fr) | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
CH557178A (de) | 1972-08-10 | 1974-12-31 | Siemens Ag | Geraet fuer die zufuehrung von medikamenten. |
US3923060A (en) | 1974-04-23 | 1975-12-02 | Jr Everett H Ellinwood | Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means |
US4140109A (en) | 1977-10-17 | 1979-02-20 | Savic Michael I | Impedance-based method and apparatus for monitoring cryodestruction in controlled cryosurgery |
FR2460343A1 (fr) | 1979-06-29 | 1981-01-23 | Solvay | Cathode pour la production electrolytique d'hydrogene |
JPS5683360A (en) * | 1979-12-10 | 1981-07-07 | Olympus Optical Co | Pneumoperitoneum needle |
US4447225A (en) | 1982-03-22 | 1984-05-08 | Taff Barry E | Multidose jet injector |
US4619652A (en) | 1982-12-23 | 1986-10-28 | Alza Corporation | Dosage form for use in a body mounted pump |
US4505710A (en) | 1983-05-13 | 1985-03-19 | Collins Earl R | Implantable fluid dispensing system |
DE3502913C1 (de) | 1985-01-29 | 1986-07-03 | Günter Prof. Dr.rer.nat. 5100 Aachen Rau | Messaufnehmer zur nichtinvasiven Erfassung elektrophysiologischer Groessen |
US4777599A (en) | 1985-02-26 | 1988-10-11 | Gillette Company | Viscoelastometry of skin using shear wave propagation |
FR2594341B1 (fr) * | 1986-02-14 | 1990-08-10 | Charton Jean Pierre | Appareil injecteur pour la pratique de la mesotherapie |
AT384737B (de) | 1986-04-04 | 1987-12-28 | Thoma Dipl Ing Dr Techn Herwig | Vorrichtung zur stroemungskonstanten abgabe fluessiger arzneimittel |
EP0260953B1 (en) * | 1986-09-18 | 1994-03-30 | Paul G. Yock | Device for use in the cannulation of blood vessels |
CA1283827C (en) | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Appliance for injection of liquid formulations |
US4808156A (en) | 1987-03-09 | 1989-02-28 | Dean Consuelo M | Cannular instrument and method for inserting a cannular instrument into a vein |
US6056716A (en) | 1987-06-08 | 2000-05-02 | D'antonio Consultants International Inc. | Hypodermic fluid dispenser |
DD262803A1 (de) | 1987-08-05 | 1988-12-14 | Transform Roentgen Matern Veb | Injektionseinrichtung |
US5312486A (en) | 1987-12-24 | 1994-05-17 | Frank Meyer | Water-containing, hardenable foam compositions with inorganic components and process for their preparation |
US4989614A (en) | 1988-02-23 | 1991-02-05 | Vance Products Incorporated | Fine-needle aspiration cell sampling methods |
CA2008262A1 (en) * | 1989-01-30 | 1990-07-30 | John A. Gilly | Clinical applicator |
US5062834A (en) | 1989-02-24 | 1991-11-05 | Product Development (S.G.Z.) Ltd | Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate |
US5425706A (en) | 1989-02-24 | 1995-06-20 | S. I. Scientific Innovations Ltd. | Dispensing device particularly useful for dispensing nutritional liquids |
JPH0648975B2 (ja) | 1989-10-02 | 1994-06-29 | 俊郎 樋口 | 微小インジェクション装置及びそのインジェクション制御方法 |
US5262128A (en) | 1989-10-23 | 1993-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Array-type multiple cell injector |
EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US6090790A (en) | 1989-12-14 | 2000-07-18 | Eriksson; Elof | Gene delivery by microneedle injection |
US5697901A (en) | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
US5092901A (en) | 1990-06-06 | 1992-03-03 | The Royal Institution For The Advancement Of Learning (Mcgill University) | Shape memory alloy fibers having rapid twitch response |
US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
US5156591A (en) | 1990-12-13 | 1992-10-20 | S. I. Scientific Innovations Ltd. | Skin electrode construction and transdermal drug delivery device utilizing same |
US5279544A (en) * | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
TW279133B (ja) | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
US5279547A (en) | 1991-01-03 | 1994-01-18 | Alcon Surgical Inc. | Computer controlled smart phacoemulsification method and apparatus |
SE9101022D0 (sv) * | 1991-01-09 | 1991-04-08 | Paal Svedman | Medicinsk suganordning |
US5312456A (en) | 1991-01-31 | 1994-05-17 | Carnegie Mellon University | Micromechanical barb and method for making the same |
ATE155045T1 (de) | 1991-11-13 | 1997-07-15 | Elan Corp Plc | Vorrichtung zur verabreichung von heilmitteln |
US6048337A (en) | 1992-01-07 | 2000-04-11 | Principal Ab | Transdermal perfusion of fluids |
EP0623008A1 (en) | 1992-01-21 | 1994-11-09 | Valleylab, Inc. | Electrosurgical control for a trocar |
US5252023A (en) * | 1992-02-10 | 1993-10-12 | Kelly Kevin M | Lifting apparatus |
JP2572823Y2 (ja) | 1992-02-13 | 1998-05-25 | 株式会社アドバンス | 簡易採血器 |
AU4282793A (en) | 1992-04-10 | 1993-11-18 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | A microneedle for injection of ocular blood vessels |
US5478328A (en) | 1992-05-22 | 1995-12-26 | Silverman; David G. | Methods of minimizing disease transmission by used hypodermic needles, and hypodermic needles adapted for carrying out the method |
JPH0698920A (ja) * | 1992-09-21 | 1994-04-12 | Hayashi Shigetada | 鍼灸精密測定器 |
US5354273A (en) | 1992-12-14 | 1994-10-11 | Mallinckrodt Medical, Inc. | Delivery apparatus with pressure controlled delivery |
US5478323A (en) * | 1993-04-02 | 1995-12-26 | Eli Lilly And Company | Manifold for injection apparatus |
IE68890B1 (en) | 1993-04-08 | 1996-07-24 | Elan Med Tech | Intradermal delivery device |
US5335668A (en) * | 1993-04-30 | 1994-08-09 | Medical Scientific, Inc. | Diagnostic impedance measuring system for an insufflation needle |
JP3494183B2 (ja) * | 1993-08-10 | 2004-02-03 | 株式会社アドバンス | 簡易採血装置 |
EP0746365A4 (en) | 1993-09-14 | 1997-05-21 | North Shore Lab Pty Ltd | INJECTION DEVICE |
US5389222A (en) | 1993-09-21 | 1995-02-14 | The United States Of America As Represented By The United States Department Of Energy | Spring-loaded polymeric gel actuators |
US5599346A (en) | 1993-11-08 | 1997-02-04 | Zomed International, Inc. | RF treatment system |
US5997501A (en) | 1993-11-18 | 1999-12-07 | Elan Corporation, Plc | Intradermal drug delivery device |
CA2149836C (en) | 1994-05-23 | 1999-07-06 | Sang Bae Choi | Perforating device for dermal administration |
US5611806A (en) | 1994-05-23 | 1997-03-18 | Samsung Electro-Mechanics Co., Ltd. | Skin perforating device for transdermal medication |
US5591139A (en) | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
DE4420232A1 (de) | 1994-06-07 | 1995-12-14 | Robert Waltereit | Vorrichtung zur Prüfung der Eindringtiefe einer Kanüle oder Sonde in den Körper eines Patienten |
US5649423A (en) | 1994-06-07 | 1997-07-22 | Sandia Corporation | Micromechanism linear actuator with capillary force sealing |
US5478315A (en) | 1994-08-08 | 1995-12-26 | Brothers Family Investments, L.C. | Local anesthetic injection system |
US5432098A (en) | 1994-10-31 | 1995-07-11 | Dynatech Precision Sampling Corporation | Apparatus, and process, for automatically sampling solids and semi-solids materials for analysis |
IE72524B1 (en) * | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
GB9508606D0 (en) | 1995-04-27 | 1995-06-14 | Svedman Paul | Suction blister sampling |
WO1996037155A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical device and method for enhancing delivery of compounds through the skin |
AU5869796A (en) | 1995-05-22 | 1996-12-11 | Ned A. Godshall | Micromechanical patch for enhancing the delivery of compound s through the skin |
US5827216A (en) | 1995-06-07 | 1998-10-27 | Cormedics Corp. | Method and apparatus for accessing the pericardial space |
ZA9610374B (en) * | 1995-12-11 | 1997-06-23 | Elan Med Tech | Cartridge-based drug delivery device |
JPH09192218A (ja) * | 1996-01-16 | 1997-07-29 | Hitachi Ltd | 血糖値管理システム |
JPH09239031A (ja) * | 1996-03-09 | 1997-09-16 | Honda Electron Co Ltd | 超音波振動子を装着した注射器 |
US5843016A (en) | 1996-03-18 | 1998-12-01 | Physion S.R.L. | Electromotive drug administration for treatment of acute urinary outflow obstruction |
US6117155A (en) | 1996-05-01 | 2000-09-12 | Lee; Young H. | Coated needle for use with an intramuscular stimulation treatment device |
US5785688A (en) | 1996-05-07 | 1998-07-28 | Ceramatec, Inc. | Fluid delivery apparatus and method |
US5954668A (en) | 1996-06-14 | 1999-09-21 | Medrad, Inc. | Extravasation detector using microwave radiometry |
CA2253549C (en) | 1996-06-18 | 2005-10-25 | Alza Corporation | Device for enhancing transdermal agent delivery or sampling |
ES2200187T3 (es) | 1996-07-03 | 2004-03-01 | Altea Therapeutics Corporation | Microporacion mecanica multiple de la piel o de la mucosa. |
JPH1043296A (ja) * | 1996-08-05 | 1998-02-17 | Terumo Corp | 薬液注入器具 |
WO1998011937A1 (en) | 1996-09-17 | 1998-03-26 | Deka Products Limited Partnership | System for delivery of drugs by transport |
US6093156A (en) | 1996-12-06 | 2000-07-25 | Abbott Laboratories | Method and apparatus for obtaining blood for diagnostic tests |
SE9604564D0 (sv) | 1996-12-12 | 1996-12-12 | Paal Svedman | Sätt och anordning vid avledning av elektriska strömmar |
US6246904B1 (en) | 1996-12-17 | 2001-06-12 | Alza Corporation | Electrotransport drug delivery reservoirs containing inert fillers |
US5928194A (en) | 1997-04-07 | 1999-07-27 | Maget; Henri J. R. | Self-contained liquid microdispenser |
US5928207A (en) | 1997-06-30 | 1999-07-27 | The Regents Of The University Of California | Microneedle with isotropically etched tip, and method of fabricating such a device |
US5972013A (en) | 1997-09-19 | 1999-10-26 | Comedicus Incorporated | Direct pericardial access device with deflecting mechanism and method |
JPH11137684A (ja) * | 1997-11-12 | 1999-05-25 | Hiroshi Oya | 無痛安全注射器 |
EP1032441B1 (en) * | 1997-11-26 | 2004-03-03 | E-Z-Em, Inc. | Extravasation detection device |
US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
AU739616B2 (en) | 1997-12-11 | 2001-10-18 | Alza Corporation | Device for enhancing transdermal agent flux |
KR100561892B1 (ko) | 1997-12-11 | 2006-03-16 | 알자 코포레이션 | 경피성 작용제 유동률을 증진시키기 위한 장치 |
US6126629A (en) | 1997-12-18 | 2000-10-03 | Bausch & Lomb Surgical, Inc. | Multiple port phaco needle |
US6154673A (en) * | 1997-12-30 | 2000-11-28 | Agilent Technologies, Inc. | Multilingual defibrillator |
US6048204A (en) * | 1998-02-03 | 2000-04-11 | Lifecore Biomedical, Inc. | Self tapping screw type dental implant |
US5957895A (en) | 1998-02-20 | 1999-09-28 | Becton Dickinson And Company | Low-profile automatic injection device with self-emptying reservoir |
US6391005B1 (en) * | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US5971998A (en) | 1998-03-31 | 1999-10-26 | Donald G. Russell | Support device and method for controlling breast thickness during stereotactic guided needle biopsy |
PT1077636E (pt) | 1998-05-13 | 2004-06-30 | Cygnus Therapeutic Systems | Processamento de sinal para medicao de analitos fisiologicos |
CA2332112C (en) | 1998-05-13 | 2004-02-10 | Cygnus, Inc. | Monitoring of physiological analytes |
EP1082151A1 (en) | 1998-06-04 | 2001-03-14 | ELAN CORPORATION, Plc | Gas driven drug delivery device |
CA2330207C (en) | 1998-06-10 | 2005-08-30 | Georgia Tech Research Corporation | Microneedle devices and methods of manufacture and use thereof |
US6678556B1 (en) | 1998-07-13 | 2004-01-13 | Genetronics, Inc. | Electrical field therapy with reduced histopathological change in muscle |
GB9815820D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Improvements relating to micro-machining |
GB9815819D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Transferring materials into cells and a microneedle array |
US6123684A (en) | 1998-07-27 | 2000-09-26 | Medi-Ject Corporation | Loading mechanism for medical injector assembly |
EP1113832A4 (en) | 1998-09-18 | 2002-04-17 | Univ Utah Res Found | MICRO-MACHINED NEEDLES ON A SURFACE |
DE19843733A1 (de) | 1998-09-24 | 2000-03-30 | Voith Sulzer Papiertech Patent | Rakelvorrichtung |
US6148232A (en) | 1998-11-09 | 2000-11-14 | Elecsys Ltd. | Transdermal drug delivery and analyte extraction |
US6317630B1 (en) | 1999-01-29 | 2001-11-13 | Yossi Gross | Drug delivery device |
US6132449A (en) | 1999-03-08 | 2000-10-17 | Agilent Technologies, Inc. | Extraction and transportation of blood for analysis |
US6319230B1 (en) | 1999-05-07 | 2001-11-20 | Scimed Life Systems, Inc. | Lateral needle injection apparatus and method |
CA2376128C (en) | 1999-06-04 | 2009-01-06 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6611707B1 (en) | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
WO2000078212A1 (en) * | 1999-06-18 | 2000-12-28 | University Of Virginia Patent Foundation | An apparatus for fluid transport and related method thereof |
US6408204B1 (en) | 1999-07-28 | 2002-06-18 | Medrad, Inc. | Apparatuses and methods for extravasation detection |
MXPA02004863A (es) * | 1999-11-15 | 2003-01-28 | Velcro Ind | Miembro de sujecion dermica. |
PT1239775E (pt) * | 1999-12-16 | 2005-05-31 | Alza Corp | Dispositivo para aumentar o fluxo transdermal de amostras de agentes |
US7003336B2 (en) * | 2000-02-10 | 2006-02-21 | Medtronic Minimed, Inc. | Analyte sensor method of making the same |
US6572740B2 (en) | 2000-04-13 | 2003-06-03 | Elan Pharma International Limited | Electrolytic cell |
US6565532B1 (en) | 2000-07-12 | 2003-05-20 | The Procter & Gamble Company | Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup |
US6440096B1 (en) * | 2000-07-14 | 2002-08-27 | Becton, Dickinson And Co. | Microdevice and method of manufacturing a microdevice |
JP2002028247A (ja) * | 2000-07-18 | 2002-01-29 | Japan Science & Technology Corp | 穿刺針による静脈刺入の感知方法及び装置 |
AU2002241567A1 (en) | 2000-11-30 | 2002-07-24 | Biovalve Technologies, Inc. | Fluid delivery and measurement systems and methods |
DE60212837T2 (de) | 2001-06-11 | 2007-06-21 | Glaxo Group Ltd., Greenford | Medikamentenspender |
US6835193B2 (en) | 2001-07-10 | 2004-12-28 | Myocardial Therapeutics, Inc. | Methods for controlled depth injections into interior body cavities |
US7429258B2 (en) * | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
WO2003059192A2 (en) * | 2001-12-21 | 2003-07-24 | The Trustees Of Columbia University In The City Of New York | C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis |
EP1403519A1 (en) * | 2002-09-27 | 2004-03-31 | Novo Nordisk A/S | Membrane pump with stretchable pump membrane |
-
2002
- 2002-09-09 US US10/238,844 patent/US7429258B2/en not_active Expired - Fee Related
- 2002-10-18 WO PCT/US2002/033544 patent/WO2003037403A1/en active Application Filing
- 2002-10-18 DE DE60230896T patent/DE60230896D1/de not_active Expired - Lifetime
- 2002-10-18 AT AT02789233T patent/ATE420680T1/de not_active IP Right Cessation
- 2002-10-18 AU AU2002353840A patent/AU2002353840B2/en not_active Ceased
- 2002-10-18 CA CA2464483A patent/CA2464483C/en not_active Expired - Fee Related
- 2002-10-18 EP EP02789233A patent/EP1439871B1/en not_active Expired - Lifetime
- 2002-10-18 JP JP2003539742A patent/JP2005525141A/ja active Pending
- 2002-10-21 US US10/278,050 patent/US7066922B2/en not_active Expired - Lifetime
- 2002-10-21 WO PCT/US2002/033794 patent/WO2003037404A1/en active IP Right Grant
- 2002-10-21 US US10/278,049 patent/US7364568B2/en not_active Expired - Fee Related
- 2002-10-21 EP EP02782208A patent/EP1446176B1/en not_active Expired - Lifetime
- 2002-10-21 CA CA2464485A patent/CA2464485C/en not_active Expired - Fee Related
- 2002-10-21 JP JP2003539743A patent/JP4612304B2/ja not_active Expired - Fee Related
- 2002-10-21 DE DE60225172T patent/DE60225172D1/de not_active Expired - Lifetime
- 2002-10-21 US US10/277,722 patent/US7645263B2/en not_active Expired - Fee Related
- 2002-10-21 AT AT02782208T patent/ATE386561T1/de not_active IP Right Cessation
- 2002-10-21 US US10/277,724 patent/US20030083618A1/en not_active Abandoned
- 2002-10-22 AT AT02784221T patent/ATE419885T1/de not_active IP Right Cessation
- 2002-10-22 JP JP2003539746A patent/JP4610193B2/ja not_active Expired - Fee Related
- 2002-10-22 AU AU2002353855A patent/AU2002353855B2/en not_active Ceased
- 2002-10-22 EP EP02784221A patent/EP1448253B1/en not_active Expired - Lifetime
- 2002-10-22 CA CA2464673A patent/CA2464673C/en not_active Expired - Fee Related
- 2002-10-22 DE DE60230795T patent/DE60230795D1/de not_active Expired - Lifetime
- 2002-10-22 WO PCT/US2002/033823 patent/WO2003037405A1/en active Application Filing
- 2002-10-22 AU AU2002348009A patent/AU2002348009B9/en not_active Ceased
- 2002-10-22 WO PCT/US2002/033829 patent/WO2003037406A2/en not_active Application Discontinuation
- 2002-10-22 EP EP02784220A patent/EP1438092A2/en not_active Withdrawn
- 2002-10-22 JP JP2003539745A patent/JP2005507715A/ja active Pending
- 2002-10-22 CA CA002464487A patent/CA2464487A1/en not_active Abandoned
- 2002-10-22 EP EP02789250A patent/EP1443990A1/en not_active Ceased
- 2002-10-22 JP JP2003539744A patent/JP4610192B2/ja not_active Expired - Fee Related
- 2002-10-22 WO PCT/US2002/033830 patent/WO2003037407A1/en active Application Filing
- 2002-10-22 CA CA2464670A patent/CA2464670C/en not_active Expired - Fee Related
-
2005
- 2005-10-19 JP JP2005304325A patent/JP2006081918A/ja active Pending
-
2008
- 2008-01-11 US US11/972,726 patent/US7651475B2/en not_active Expired - Fee Related
- 2008-04-29 US US12/150,606 patent/US8246582B2/en not_active Expired - Fee Related
-
2009
- 2009-05-11 JP JP2009114992A patent/JP2009219888A/ja active Pending
- 2009-05-11 JP JP2009114989A patent/JP2009219886A/ja active Pending
- 2009-05-11 JP JP2009114991A patent/JP2009219887A/ja active Pending
- 2009-05-11 JP JP2009114990A patent/JP2009240790A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4610192B2 (ja) | インピーダンス・センサ | |
AU2002353855A1 (en) | Impedance sensor | |
AU2002348009A1 (en) | Transdermal transport device with suction | |
AU2002353840A1 (en) | Microneedle transport device | |
AU2002348386A1 (en) | Microneedle transdermal transport device | |
AU2002348008A1 (en) | Transdermal transport device with an electrolytic actuator |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20051019 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20081111 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20090116 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090226 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20090212 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090511 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20091013 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100105 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100113 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100413 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100914 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20101012 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20131022 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |