|
US4235871A
(en)
|
1978-02-24 |
1980-11-25 |
Papahadjopoulos Demetrios P |
Method of encapsulating biologically active materials in lipid vesicles
|
|
US4722848A
(en)
|
1982-12-08 |
1988-02-02 |
Health Research, Incorporated |
Method for immunizing animals with synthetically modified vaccinia virus
|
|
US4501728A
(en)
|
1983-01-06 |
1985-02-26 |
Technology Unlimited, Inc. |
Masking of liposomes from RES recognition
|
|
GB8311018D0
(en)
|
1983-04-22 |
1983-05-25 |
Amersham Int Plc |
Detecting mutations in dna
|
|
US6090406A
(en)
|
1984-04-12 |
2000-07-18 |
The Liposome Company, Inc. |
Potentiation of immune responses with liposomal adjuvants
|
|
US5019369A
(en)
|
1984-10-22 |
1991-05-28 |
Vestar, Inc. |
Method of targeting tumors in humans
|
|
US4837028A
(en)
|
1986-12-24 |
1989-06-06 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5223427A
(en)
|
1987-03-31 |
1993-06-29 |
The Scripps Research Institute |
Hybridomas producing monoclonal antibodies reactive with human tissue-factor glycoprotein heavy chain
|
|
US5217879A
(en)
|
1989-01-12 |
1993-06-08 |
Washington University |
Infectious Sindbis virus vectors
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
FR2650840B1
(fr)
|
1989-08-11 |
1991-11-29 |
Bertin & Cie |
Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
|
|
EP0452457B1
(en)
|
1989-11-03 |
1997-08-20 |
Vanderbilt University |
Method of in vivo delivery of functioning foreign genes
|
|
US5670488A
(en)
*
|
1992-12-03 |
1997-09-23 |
Genzyme Corporation |
Adenovirus vector for gene therapy
|
|
US5279833A
(en)
|
1990-04-04 |
1994-01-18 |
Yale University |
Liposomal transfection of nucleic acids into animal cells
|
|
US5204253A
(en)
|
1990-05-29 |
1993-04-20 |
E. I. Du Pont De Nemours And Company |
Method and apparatus for introducing biological substances into living cells
|
|
US6770283B1
(en)
|
1990-12-13 |
2004-08-03 |
Bioption Ab |
DNA expression systems based on alphaviruses
|
|
US6004744A
(en)
|
1991-03-05 |
1999-12-21 |
Molecular Tool, Inc. |
Method for determining nucleotide identity through extension of immobilized primer
|
|
US6037135A
(en)
|
1992-08-07 |
2000-03-14 |
Epimmune Inc. |
Methods for making HLA binding peptides and their uses
|
|
EP0646178A1
(en)
|
1992-06-04 |
1995-04-05 |
The Regents Of The University Of California |
expression cassette with regularoty regions functional in the mammmlian host
|
|
US5662907A
(en)
|
1992-08-07 |
1997-09-02 |
Cytel Corporation |
Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes
|
|
US9340577B2
(en)
|
1992-08-07 |
2016-05-17 |
Epimmune Inc. |
HLA binding motifs and peptides and their uses
|
|
US20050271676A1
(en)
|
1993-03-05 |
2005-12-08 |
Epimmune Inc. |
Inducing cellular immune responses to human immunodeficiency virus-1 using peptide and nucleic acid compositions
|
|
DE69435171D1
(de)
|
1993-09-14 |
2009-01-08 |
Pharmexa Inc |
Pan dr-bindeproteinen zur erhöhung der immunantwort
|
|
US6413935B1
(en)
|
1993-09-14 |
2002-07-02 |
Epimmune Inc. |
Induction of immune response against desired determinants
|
|
US6015686A
(en)
|
1993-09-15 |
2000-01-18 |
Chiron Viagene, Inc. |
Eukaryotic layered vector initiation systems
|
|
DK0814154T3
(da)
|
1993-09-15 |
2009-08-31 |
Novartis Vaccines & Diagnostic |
Rekombinante alfavirusvektorer
|
|
PT728214E
(pt)
|
1993-11-09 |
2004-11-30 |
Ohio Med College |
Linhas celulares estaveis capazes de expressar o gene de replicacao do virus adeno-associado
|
|
US5505947A
(en)
|
1994-05-27 |
1996-04-09 |
The University Of North Carolina At Chapel Hill |
Attenuating mutations in Venezuelan Equine Encephalitis virus
|
|
US5851806A
(en)
|
1994-06-10 |
1998-12-22 |
Genvec, Inc. |
Complementary adenoviral systems and cell lines
|
|
DE69534166T2
(de)
|
1994-10-28 |
2006-03-09 |
Trustees Of The University Of Pennsylvania |
Rekombinanter adenovirus und methoden zu dessen verwendung
|
|
FR2726285B1
(fr)
|
1994-10-28 |
1996-11-29 |
Centre Nat Rech Scient |
Adenovirus depourvus de particules contaminantes viables, preparation et utilisation
|
|
US5552350A
(en)
|
1994-12-12 |
1996-09-03 |
Ceramco Inc. |
Low-fusing temperature porcelain
|
|
WO1996018418A1
(en)
*
|
1994-12-12 |
1996-06-20 |
Genetic Therapy, Inc. |
Improved adenoviral vectors and producer cells
|
|
US5792462A
(en)
|
1995-05-23 |
1998-08-11 |
University Of North Carolina At Chapel Hill |
Alphavirus RNA replicon systems
|
|
US5851796A
(en)
*
|
1995-06-07 |
1998-12-22 |
Yale University |
Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes
|
|
UY24367A1
(es)
|
1995-11-23 |
2000-10-31 |
Boehringer Ingelheim Int |
Vacunas contra tumores y procedimiento para su produccion
|
|
US5849589A
(en)
|
1996-03-11 |
1998-12-15 |
Duke University |
Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells
|
|
US6451592B1
(en)
|
1996-04-05 |
2002-09-17 |
Chiron Corporation |
Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
|
|
EP0803573A1
(en)
|
1996-04-25 |
1997-10-29 |
Gesellschaft für Biotechnologische Forschung mbH (GBF) |
Polycistronic expression construct with cytokines for multivalent vaccines
|
|
US6514731B1
(en)
|
1996-05-24 |
2003-02-04 |
Chiron Corporation |
Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
|
|
CA2259179C
(en)
|
1996-07-03 |
2008-09-23 |
University Of Pittsburgh |
Emulsion formulations for hydrophilic active agents
|
|
WO1998010087A1
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
Chimpanzee adenovirus vectors
|
|
US5994132A
(en)
*
|
1996-10-23 |
1999-11-30 |
University Of Michigan |
Adenovirus vectors
|
|
US7732129B1
(en)
|
1998-12-01 |
2010-06-08 |
Crucell Holland B.V. |
Method for the production and purification of adenoviral vectors
|
|
US5849561A
(en)
|
1997-05-22 |
1998-12-15 |
Cornell Research Foundation, Inc. |
Method for the production of non-group C adenoviral vectors
|
|
ES2180258T3
(es)
|
1998-07-07 |
2003-02-01 |
Transgene Sa |
Utilizacion de pautas de lectura abierta adenovirales de e4 para mejorar la expresion de genes.
|
|
EP1000628A1
(en)
|
1998-09-28 |
2000-05-17 |
Fondation Mondiale Recherche et Prevention SIDA |
Use of antigenic complexes of HIV envelope and HLA class I antigens as HIV vaccine
|
|
US20030072767A1
(en)
|
1998-09-30 |
2003-04-17 |
Alexander Gaiger |
Compositions and methods for WT1 specific immunotherapy
|
|
US20080050393A1
(en)
|
1998-12-03 |
2008-02-28 |
Tang Y Tom |
Novel nucleic acids and polypeptides
|
|
CA2354374A1
(en)
|
1998-12-07 |
2000-06-15 |
U.S. Medical Research Institute Of Infectious Diseases |
Live attenuated venezuelan equine encephalitis vaccine
|
|
WO2000047229A2
(en)
|
1999-02-11 |
2000-08-17 |
Genzyme Corporation |
Polynucleotide encoding multimers of antigenic peptides in order to enhance presentation of the antigenic peptide by mhc molecules
|
|
US7262049B2
(en)
*
|
1999-03-16 |
2007-08-28 |
Dana-Farber Cancer Institute, Inc. |
Pseudotyped lentiviral vectors and uses thereof
|
|
DE60038011T2
(de)
|
1999-04-08 |
2009-02-12 |
Novartis Vaccines and Diagnostics, Inc., Emeryville |
Verbesserung der immunantwort als anwendung in impfstoff und gentherapie
|
|
US8647864B2
(en)
|
1999-04-14 |
2014-02-11 |
Novartis Ag |
Compositions and methods for generating an immune response utilizing alphavirus-based vector systems
|
|
DE60044125D1
(de)
|
1999-04-14 |
2010-05-20 |
Novartis Vaccines & Diagnostic |
Zusammensetzungen und verfahren zur auslösung einer immunantwort auf basis alphavirus-vektoren-systeme
|
|
WO2003104467A1
(en)
|
2002-04-25 |
2003-12-18 |
Crucell Holland B.V. |
Means and methods for the production of adenovirus vectors
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
JP2003521245A
(ja)
|
1999-12-21 |
2003-07-15 |
エピミューン， インコーポレイテッド |
ペプチドおよび核酸組成物を使用する、前立腺癌抗原に対する細胞性免疫応答の誘導
|
|
US20040248113A1
(en)
|
1999-12-28 |
2004-12-09 |
Alessandro Sette |
Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby
|
|
US7462354B2
(en)
|
1999-12-28 |
2008-12-09 |
Pharmexa Inc. |
Method and system for optimizing minigenes and peptides encoded thereby
|
|
EP1242108B1
(en)
|
1999-12-28 |
2007-07-11 |
Pharmexa Inc. |
Optimized minigenes and peptides encoded thereby
|
|
WO2001055393A2
(en)
|
2000-01-28 |
2001-08-02 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Mhc class ii restricted t cell epitopes from the cancer antigen ny-eso-1
|
|
WO2001055177A2
(en)
|
2000-01-28 |
2001-08-02 |
Statens Serum Institut |
Methods to identify ctl epitopes of hiv
|
|
US20010055596A1
(en)
|
2000-03-24 |
2001-12-27 |
Meagher Madeleine Joy |
Compositions and methods for therapy and diagnosis of colon cancer
|
|
US6436703B1
(en)
|
2000-03-31 |
2002-08-20 |
Hyseq, Inc. |
Nucleic acids and polypeptides
|
|
US20040115625A1
(en)
|
2000-10-02 |
2004-06-17 |
Reinhard Ebner |
Cancer gene determination and therapeutic screening using signature gene sets
|
|
US6783939B2
(en)
|
2000-07-07 |
2004-08-31 |
Alphavax, Inc. |
Alphavirus vectors and virosomes with modified HIV genes for use in vaccines
|
|
EP2336339A3
(en)
|
2000-09-25 |
2011-09-14 |
The Regents of the University of Michigan |
Production of viral vectors
|
|
US20020137081A1
(en)
|
2001-01-08 |
2002-09-26 |
Olga Bandman |
Genes differentially expressed in vascular tissue activation
|
|
WO2002061113A2
(en)
|
2001-02-01 |
2002-08-08 |
The Johns Hopkins University |
Nucleic acid derived vaccine that encodes an antigen linked to a polypeptide that promotes antigen presentation
|
|
CN1147587C
(zh)
*
|
2001-05-30 |
2004-04-28 |
方炳良 |
一种增强细胞特异性目的基因表达的方法
|
|
JP4608210B2
(ja)
|
2001-05-31 |
2011-01-12 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
キメラアルファウイルスレプリコン粒子
|
|
US20030232324A1
(en)
|
2001-05-31 |
2003-12-18 |
Chiron Corporation |
Chimeric alphavirus replicon particles
|
|
EP1409748B1
(en)
|
2001-06-22 |
2011-10-26 |
The Trustees of The University of Pennsylvania |
Recombinant Adenoviruses comprising simian adenovirus proteins and uses thereof.
|
|
EP1497440B1
(en)
|
2002-04-25 |
2008-08-20 |
Crucell Holland B.V. |
Stable adenoviral vectors and methods for propagation thereof
|
|
WO2004023973A2
(en)
|
2002-09-12 |
2004-03-25 |
Incyte Corporation |
Molecules for diagnostics and therapeutics
|
|
AU2003295328A1
(en)
|
2002-10-02 |
2004-04-23 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
CA2500955A1
(en)
|
2002-10-03 |
2004-04-15 |
Genencor International, Inc. |
Optimized multi-epitope constructs and uses thereof
|
|
US7078218B2
(en)
|
2002-12-13 |
2006-07-18 |
Alphavax, Inc. |
Alphavirus particles and methods for preparation
|
|
US20040208848A1
(en)
|
2002-12-13 |
2004-10-21 |
Smith Jonathan F. |
Multi-antigenic alphavirus replicon particles and methods
|
|
GB2398300A
(en)
|
2003-02-17 |
2004-08-18 |
Isis Innovation |
Method and compositions for boosting immune response
|
|
US7425328B2
(en)
|
2003-04-22 |
2008-09-16 |
Purdue Pharma L.P. |
Tissue factor antibodies and uses thereof
|
|
WO2005033265A2
(en)
|
2003-04-25 |
2005-04-14 |
Epimmune Inc. |
Optimized multi-epitope constructs and uses thereof
|
|
US7605235B2
(en)
|
2003-05-30 |
2009-10-20 |
Centocor, Inc. |
Anti-tissue factor antibodies and compositions
|
|
KR20060017635A
(ko)
|
2003-06-05 |
2006-02-24 |
와이어쓰 홀딩스 코포레이션 |
베네쥬엘라 말 뇌염 바이러스 레플리콘 벡터 및파라믹소바이러스 단백질 항원을 포함하는 면역원성 조성물
|
|
US7291498B2
(en)
|
2003-06-20 |
2007-11-06 |
The Trustees Of The University Of Pennsylvania |
Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses
|
|
DE10347710B4
(de)
|
2003-10-14 |
2006-03-30 |
Johannes-Gutenberg-Universität Mainz |
Rekombinante Impfstoffe und deren Verwendung
|
|
DE602005017743D1
(de)
|
2004-01-23 |
2009-12-31 |
Angeletti P Ist Richerche Bio |
Impfstoffträger für schimpansen-adenovirus
|
|
US8119336B2
(en)
|
2004-03-03 |
2012-02-21 |
Ibis Biosciences, Inc. |
Compositions for use in identification of alphaviruses
|
|
CA2563500C
(en)
*
|
2004-04-28 |
2016-06-28 |
The Trustees Of The University Of Pennsylvania |
Immunization regimen with e4-deleted adenovirus prime and e1-deleted adenovirus boost
|
|
ES2361000T3
(es)
*
|
2004-04-28 |
2011-06-13 |
The Trustees Of The University Of Pennsylvania |
Suministro secuencial de moléculas inmunogénicas mediante administraciones de un adenovirus y de un virus adeno-asociado.
|
|
EP2848692B1
(en)
|
2004-05-21 |
2017-08-16 |
Novartis Vaccines and Diagnostics, Inc. |
Alphavirus vectors for influenza virus vaccines
|
|
JP5689576B2
(ja)
|
2004-05-25 |
2015-03-25 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド |
αウイルスレプリコンパッケージング構築物
|
|
US20060051405A1
(en)
|
2004-07-19 |
2006-03-09 |
Protiva Biotherapeutics, Inc. |
Compositions for the delivery of therapeutic agents and uses thereof
|
|
CN101056977B
(zh)
|
2004-10-04 |
2013-01-30 |
拜欧瓦克西姆有限公司 |
用于治疗hiv感染患者的亚型匹配的灭活全病毒疫苗
|
|
US20060198854A1
(en)
|
2004-12-28 |
2006-09-07 |
Peter Pushko |
Vector platforms derived from the alphavirus vaccines
|
|
US7220549B2
(en)
|
2004-12-30 |
2007-05-22 |
Helicos Biosciences Corporation |
Stabilizing a nucleic acid for nucleic acid sequencing
|
|
FR2882557A1
(fr)
|
2005-02-25 |
2006-09-01 |
Centre Nat Rech Scient |
Epitopes de vih et composition pharmaceutique les contenant
|
|
US7283337B2
(en)
|
2005-03-04 |
2007-10-16 |
Headway Technologies, Inc. |
Abutted exchange bias design for sensor stabilization
|
|
CA2609142C
(en)
*
|
2005-05-27 |
2016-02-09 |
Fondazione Centro San Raffaele Del Monte Tabor |
Therapeutic gene vectors comprising mirna target sequences
|
|
PL2578685T3
(pl)
|
2005-08-23 |
2020-01-31 |
The Trustees Of The University Of Pennsylvania |
Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania
|
|
CA2626253A1
(en)
|
2005-10-18 |
2007-04-26 |
Novartis Vaccines And Diagnostics, Inc. |
Mucosal and systemic immunizations with alphavirus replicon particles
|
|
KR101499750B1
(ko)
|
2006-02-27 |
2015-03-06 |
더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 |
가감염성 플라비바이러스 및 이들의 용도
|
|
CA2663295C
(en)
|
2006-09-12 |
2020-03-10 |
Alphavax, Inc. |
Alphavirus replicon particles matched to protein antigens as immunological adjuvants
|
|
US9085638B2
(en)
|
2007-03-07 |
2015-07-21 |
The Johns Hopkins University |
DNA vaccine enhancement with MHC class II activators
|
|
GB0706914D0
(en)
|
2007-04-10 |
2007-05-16 |
Isis Innovation |
Novel adenovirus vectors
|
|
EP2162540A2
(en)
|
2007-05-22 |
2010-03-17 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
|
US8969542B2
(en)
|
2007-05-31 |
2015-03-03 |
Genimmune N.V. |
HPV polyepitope constructs and uses thereof
|
|
US8460913B2
(en)
|
2007-06-21 |
2013-06-11 |
Alpha Vax, Inc. |
Promoterless cassettes for expression of alpha virus structural proteins
|
|
US20100015179A1
(en)
|
2007-08-16 |
2010-01-21 |
Frolov Ilya V |
Attenuation of encephalitogenic alphavirus and uses thereof
|
|
WO2009034190A2
(en)
|
2007-09-14 |
2009-03-19 |
Genimmune N.V. |
Affinity tag
|
|
US20100285050A1
(en)
|
2007-10-05 |
2010-11-11 |
Isis Innovation Limited |
Compositions and Methods
|
|
GB0719526D0
(en)
|
2007-10-05 |
2007-11-14 |
Isis Innovation |
Compositions and methods
|
|
AU2008338803B2
(en)
|
2007-11-26 |
2015-02-05 |
Glaxosmithkline Biologicals S.A. |
Methods of generating alphavirus particles
|
|
WO2009092113A2
(en)
|
2008-01-19 |
2009-07-23 |
Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods and compositions for the delivery of vaccines to disrupted epithelium
|
|
US20090253184A1
(en)
|
2008-01-23 |
2009-10-08 |
Introgen Therapeutics, Inc. |
Compositions and methods related to an adenoviral trans-complementing cell line
|
|
KR101668849B1
(ko)
|
2008-01-24 |
2016-10-24 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
모기에서 복제 불가능한 약독화된 재조합 알파바이러스 및 그의 용도
|
|
WO2009120947A1
(en)
|
2008-03-28 |
2009-10-01 |
Virxsys Corporation |
Lentivirus-based immunogenic vectors
|
|
WO2009146902A1
(en)
|
2008-06-03 |
2009-12-10 |
Okairòs Ag |
A vaccine for the prevention and therapy of hcv infections
|
|
US8093021B2
(en)
|
2008-06-13 |
2012-01-10 |
New York University |
Defective sindbis viral vectors
|
|
ES2544702T3
(es)
|
2008-07-17 |
2015-09-02 |
Medigen, Inc. |
Vacunas en forma de ADNi y métodos para utilizarlas
|
|
RS53782B1
(sr)
|
2008-10-01 |
2015-06-30 |
Immatics Biotechnologies Gmbh |
Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera
|
|
WO2010037402A1
(en)
|
2008-10-02 |
2010-04-08 |
Dako Denmark A/S |
Molecular vaccines for infectious disease
|
|
US8807362B2
(en)
|
2008-10-17 |
2014-08-19 |
Jeong-min Lee |
Bottle cap
|
|
EP2370455B1
(en)
|
2008-11-26 |
2019-07-03 |
Government of the United States of America, as represented by the Secretary, Department of Health and Human Services |
Virus like particle compositions and methods of use
|
|
US8680258B2
(en)
|
2008-12-01 |
2014-03-25 |
Alphavax, Inc. |
Use of microRNAs to control virus helper nucleic acids
|
|
DE102008061522A1
(de)
|
2008-12-10 |
2010-06-17 |
Biontech Ag |
Verwendung von Flt3-Ligand zur Verstärkung von Immunreaktionen bei RNA-Immunisierung
|
|
PL2391638T3
(pl)
|
2009-02-02 |
2018-11-30 |
Glaxosmithkline Biologicals Sa |
Sekwencje nukleotydowe i aminokwasowe małpiego adenowirusa, zawierające je wektory i ich zastosowania
|
|
CN101579528B
(zh)
|
2009-06-24 |
2011-06-29 |
中国人民解放军军事医学科学院军事兽医研究所 |
一种hiv复合多表位dna疫苗及其应用
|
|
GB0918154D0
(en)
|
2009-10-16 |
2009-12-02 |
Isis Innovation |
Mycobacterial vaccines
|
|
ES2647662T3
(es)
|
2009-12-31 |
2017-12-26 |
Medigen, Inc. |
Vacunas de ADN infeccioso frente al virus chikungunya
|
|
GB201006405D0
(en)
|
2010-04-16 |
2010-06-02 |
Isis Innovation |
Poxvirus expression system
|
|
EP2569633B1
(en)
|
2010-05-14 |
2016-02-10 |
The General Hospital Corporation |
Compositions and methods of identifying tumor specific neoantigens
|
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
|
MX342608B
(es)
|
2010-07-06 |
2016-10-06 |
Novartis Ag * |
Particulas de suministro similares a viriones para moleculas de arn de autorreplicacion.
|
|
ES2557382T3
(es)
|
2010-07-06 |
2016-01-25 |
Glaxosmithkline Biologicals Sa |
Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN
|
|
ES2646669T3
(es)
|
2010-07-06 |
2017-12-14 |
Glaxosmithkline Biologicals Sa |
Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN
|
|
NZ606591A
(en)
|
2010-07-06 |
2015-02-27 |
Novartis Ag |
Cationic oil-in-water emulsions
|
|
US9770463B2
(en)
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
|
EP2591114B1
(en)
|
2010-07-06 |
2016-06-08 |
GlaxoSmithKline Biologicals SA |
Immunisation of large mammals with low doses of rna
|
|
BR112013003579A2
(pt)
|
2010-08-16 |
2016-06-07 |
Salk Inst For Biological Studi |
adenovírus, células, e, métodos para tratar câncer
|
|
LT4226941T
(lt)
|
2010-08-31 |
2025-01-10 |
Glaxosmithkline Biologicals Sa |
Pegilintos liposomos, skirtos imunogeną koduojančios rnr pristatymui
|
|
SI4043040T1
(sl)
|
2010-08-31 |
2023-04-28 |
Glaxosmithkline Biologicals Sa |
Mali liposomi za dostavo imunogen-kodirajoče RNA
|
|
MX2013002332A
(es)
|
2010-08-31 |
2013-03-18 |
Novartis Ag |
Lipidos apropiados para suministro liposomal del arn que codifica la proteina.
|
|
KR102759126B1
(ko)
|
2010-12-30 |
2025-01-24 |
파운데이션 메디신 인코포레이티드 |
종양 샘플의 다유전자 분석의 최적화
|
|
US9487563B2
(en)
|
2011-01-31 |
2016-11-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Virus-like particles and methods of use
|
|
US8722044B2
(en)
|
2011-03-15 |
2014-05-13 |
Janssen Biotech, Inc. |
Human tissue factor antibody and uses thereof
|
|
CA2835644C
(en)
|
2011-05-13 |
2021-06-15 |
Novartis Ag |
Pre-fusion rsv f antigens
|
|
PL3892295T3
(pl)
|
2011-05-24 |
2023-07-24 |
BioNTech SE |
Zindywidualizowane szczepionki przeciwnowotworowe
|
|
GB201108879D0
(en)
|
2011-05-25 |
2011-07-06 |
Isis Innovation |
Vector
|
|
WO2012171541A1
(en)
|
2011-06-15 |
2012-12-20 |
Scil Proteins Gmbh |
Human fusion proteins comprising interferons and hetero-dimeric modified ubiquitin proteins
|
|
EP4115875A1
(en)
|
2011-07-06 |
2023-01-11 |
GlaxoSmithKline Biologicals S.A. |
Liposomes having useful n:p ratio for delivery of rna molecules
|
|
EP2729165B1
(en)
|
2011-07-06 |
2017-11-08 |
GlaxoSmithKline Biologicals SA |
Immunogenic combination compositions and uses thereof
|
|
CA2841047A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Immunogenic compositions and uses thereof
|
|
EP2559441B1
(en)
|
2011-08-16 |
2021-07-21 |
Samsung Electronics Co., Ltd. |
Protein complex for intracellular delivery and uses thereof
|
|
MX366055B
(es)
|
2011-08-31 |
2019-06-26 |
Novartis Ag |
Liposomas pegilados para admistracion de acido ribonucleico (arn) que codifica para inmunogeno.
|
|
RU2014118727A
(ru)
|
2011-10-11 |
2015-11-20 |
Новартис Аг |
Рекомбинантные самореплицирующиеся полицистронные молекулы рнк
|
|
KR102181258B1
(ko)
|
2012-02-16 |
2020-11-20 |
브이엘피 테라퓨틱스 엘엘씨 |
바이러스 유사 입자 조성물
|
|
US20160289674A1
(en)
|
2012-04-02 |
2016-10-06 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of membrane proteins
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
SG11201407343XA
(en)
|
2012-05-18 |
2014-12-30 |
Univ Pennsylvania |
Subfamily e simian adenoviruses a1302, a1320, a1331 and a1337 and uses thereof
|
|
EP2870236B1
(en)
|
2012-07-04 |
2018-01-10 |
Sirion Biotech GmbH |
Means and methods to increase adenovirus production
|
|
US20150140068A1
(en)
|
2012-07-06 |
2015-05-21 |
Novartis Ag |
Immunogenic compositions and uses thereof
|
|
US8961995B2
(en)
|
2012-09-20 |
2015-02-24 |
Uab Research Foundation |
Methods and compositions for alphavirus replicons
|
|
GB201220119D0
(en)
|
2012-11-08 |
2012-12-26 |
Univ Cork |
Vector
|
|
US10106781B2
(en)
|
2012-11-16 |
2018-10-23 |
Beth Israel Deaconess Medical Center, Inc. |
Recombinant adenoviruses and use thereof
|
|
KR101429696B1
(ko)
*
|
2012-11-21 |
2014-08-13 |
국립암센터 |
안전성 및 항암활성이 증가된 재조합 아데노바이러스 및 이의 용도
|
|
US9402888B2
(en)
|
2013-03-14 |
2016-08-02 |
The Wistar Institute Of Anatomy And Biology |
Methods and compositions for treating cancer
|
|
EP2983702A2
(en)
|
2013-04-07 |
2016-02-17 |
The Broad Institute, Inc. |
Compositions and methods for personalized neoplasia vaccines
|
|
SG10201709917VA
(en)
|
2013-06-03 |
2017-12-28 |
Vlp Therapeutics Llc |
Malaria vaccine
|
|
TWI636065B
(zh)
|
2013-08-05 |
2018-09-21 |
伊瑪提克斯生物科技有限公司 |
新穎肽類，細胞及其用於治療多種腫瘤的用途，其製造方法及包含其等之醫藥組成物
|
|
WO2015063647A1
(en)
*
|
2013-11-01 |
2015-05-07 |
Pfizer Inc. |
Vectors for expression of prostate-associated antigens
|
|
GB201319446D0
(en)
|
2013-11-04 |
2013-12-18 |
Immatics Biotechnologies Gmbh |
Personalized immunotherapy against several neuronal and brain tumors
|
|
US20160310584A1
(en)
|
2013-12-06 |
2016-10-27 |
The Broad Institute Inc. |
Formulations for neoplasia vaccines
|
|
KR20230076867A
(ko)
|
2013-12-20 |
2023-05-31 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신생항원 백신과의 병용 요법
|
|
CA2960096A1
(en)
|
2014-09-03 |
2016-03-10 |
Bavarian Nordic A/S |
Methods and compositions for enhancing immune responses
|
|
CN118994363A
(zh)
|
2014-11-26 |
2024-11-22 |
美国卫生和人力服务部 |
抗突变的kras的t细胞受体
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
EP3234130B1
(en)
|
2014-12-19 |
2020-11-25 |
The Broad Institute, Inc. |
Methods for profiling the t-cell- receptor repertoire
|
|
EP3250233A4
(en)
|
2015-01-29 |
2018-07-25 |
Agency for Science, Technology and Research |
Nanocapsules carrying chikungunya-associated peptides
|
|
WO2016124670A1
(en)
|
2015-02-06 |
2016-08-11 |
Scil Proteins Gmbh |
Novel binding proteins comprising a ubiquitin mutein and antibodies or antibody fragments
|
|
WO2016154047A2
(en)
|
2015-03-20 |
2016-09-29 |
Memorial Sloan-Kettering Cancer Center |
Monoclonal antigen-binding proteins to intracellular oncogene products
|
|
WO2016154246A1
(en)
|
2015-03-23 |
2016-09-29 |
The Johns Hopkins University |
Hla-restricted epitopes encoded by somatically mutated genes
|
|
IL294183B2
(en)
|
2015-05-20 |
2023-10-01 |
Dana Farber Cancer Inst Inc |
shared neoantigens
|
|
CN120842296A
(zh)
|
2015-09-21 |
2025-10-28 |
垂林克生物技术有限公司 |
用于合成5’-加帽rna的组合物和方法
|
|
MX2018004544A
(es)
|
2015-10-12 |
2018-11-09 |
Nantomics Llc |
Composiciones y métodos para los neoepítopos de cáncer viral.
|
|
ES2970865T3
(es)
|
2015-12-16 |
2024-05-31 |
Gritstone Bio Inc |
Identificación, fabricación y uso de neoantígenos
|
|
CN114959918A
(zh)
|
2016-02-29 |
2022-08-30 |
基础医疗股份有限公司 |
用于评估肿瘤突变负荷的方法和系统
|
|
CA3014466A1
(en)
|
2016-03-03 |
2017-09-08 |
Cue Biopharma, Inc. |
T-cell modulatory multimeric polypeptides and methods of use thereof
|
|
JP2019513373A
(ja)
|
2016-03-31 |
2019-05-30 |
ネオン セラピューティクス， インコーポレイテッド |
ネオ抗原およびその使用方法
|
|
AU2017254477A1
(en)
|
2016-04-18 |
2018-11-01 |
Jennifer G. ABELIN |
Improved HLA epitope prediction
|
|
EP3452082A1
(en)
|
2016-05-04 |
2019-03-13 |
Fred Hutchinson Cancer Research Center |
Cell-based neoantigen vaccines and uses thereof
|
|
BE1024796B9
(fr)
|
2016-06-02 |
2019-01-08 |
Glaxosmithkline Biologicals Sa |
Constructions antigeniques du virus zika
|
|
SG11201811442UA
(en)
|
2016-06-20 |
2019-01-30 |
Isa Pharmaceuticals B V |
Formulation of a peptide vaccine
|
|
GB2549809C
(en)
|
2016-06-23 |
2022-11-30 |
Univ Oxford Innovation Ltd |
Vector
|
|
CN107698593A
(zh)
|
2016-08-09 |
2018-02-16 |
南京天印健华医药科技有限公司 |
作为fgfr抑制剂的杂环化合物
|
|
EP3500294A4
(en)
|
2016-08-22 |
2020-07-29 |
Arbutus Biopharma Corporation |
ANTI-PD-1 ANTIBODIES, OR THEIR FRAGMENTS, FOR THE TREATMENT OF HEPATITIS B
|
|
JP2020500552A
(ja)
|
2016-11-23 |
2020-01-16 |
グリットストーン オンコロジー インコーポレイテッド |
新生抗原のウイルスによる送達方法
|
|
WO2018102585A1
(en)
|
2016-11-30 |
2018-06-07 |
Advaxis, Inc. |
Personalized immunotherapy in combination with immunotherapy targeting recurrent cancer mutations
|
|
GB201620968D0
(en)
*
|
2016-12-09 |
2017-01-25 |
Glaxosmithkline Biologicals Sa |
Adenovirus polynucleotides and polypeptides
|
|
ES2959811T3
(es)
|
2016-12-09 |
2024-02-28 |
Glaxosmithkline Biologicals Sa |
Construcciones de adenovirus de chimpancé con antígenos de Lyssavirus
|
|
GB201621732D0
(en)
|
2016-12-20 |
2017-02-01 |
Agricultural Research Council |
A multi-epitope dna vaccine for heartwater
|
|
AU2017379901B2
(en)
|
2016-12-21 |
2024-02-15 |
Arbutus Biopharma Corporation |
Methods for ameliorating infusion reactions
|
|
WO2018171103A1
(zh)
*
|
2017-03-24 |
2018-09-27 |
清华大学 |
可编程的溶瘤病毒疫苗系统及其应用
|
|
CA3058807A1
(en)
|
2017-04-03 |
2018-10-11 |
Biontech Us Inc. |
Protein antigens and uses thereof
|
|
EP3634449A4
(en)
|
2017-05-08 |
2021-03-17 |
Gritstone Oncology, Inc. |
ALPHAVIRUS NEOANTIGEN VECTORS
|
|
AU2018279627B2
(en)
|
2017-06-09 |
2023-08-10 |
Seattle Project Corp. |
Neoantigen identification, manufacture, and use
|
|
AR112166A1
(es)
|
2017-06-16 |
2019-09-25 |
Arbutus Biopharma Corp |
Composiciones terapéuticas y métodos para el tratamiento de hepatitis b
|
|
JP7760242B2
(ja)
|
2017-07-21 |
2025-10-27 |
ジェネンテック， インコーポレイテッド |
がんの治療法及び診断法
|
|
CN111868260B
(zh)
|
2017-08-07 |
2025-02-21 |
约翰斯霍普金斯大学 |
用于评估和治疗癌症的方法和材料
|
|
WO2019090156A1
(en)
|
2017-11-03 |
2019-05-09 |
Guardant Health, Inc. |
Normalizing tumor mutation burden
|
|
WO2019170773A1
(en)
|
2018-03-06 |
2019-09-12 |
Cancer Research Technology Limited |
Improvements in variant detection
|
|
JP2021524247A
(ja)
|
2018-05-23 |
2021-09-13 |
グリットストーン バイオ インコーポレイテッド |
免疫チェックポイント阻害剤の共発現ベクター
|
|
AU2019275072A1
(en)
|
2018-05-23 |
2021-01-21 |
Seattle Project Corp. |
Shared antigens
|
|
AU2019374874A1
(en)
|
2018-11-07 |
2021-06-10 |
Gritstone Bio, Inc. |
Alphavirus neoantigen vectors and interferon inhibitors
|
|
MX2021014525A
(es)
*
|
2019-05-30 |
2022-03-17 |
Gritstone Bio Inc |
Adenovirus modificados.
|
|
KR20220041844A
(ko)
|
2019-07-02 |
2022-04-01 |
그릿스톤 바이오, 인코포레이티드 |
Hiv 항원 및 mhc 복합체
|
|
WO2021092095A1
(en)
|
2019-11-04 |
2021-05-14 |
Gritstone Oncology, Inc. |
Neoantigen vaccine therapy
|
|
WO2021119545A1
(en)
|
2019-12-11 |
2021-06-17 |
Gritstone Bio, Inc. |
Durable vaccination
|
|
WO2021142437A1
(en)
|
2020-01-10 |
2021-07-15 |
Gritstone Bio, Inc. |
Cell-free dna monitoring
|
|
EP4138890A4
(en)
|
2020-04-21 |
2024-07-31 |
Gritstone bio, Inc. |
ANTIGEN CODING CASSETTES
|
|
CN116438308A
(zh)
|
2020-08-06 |
2023-07-14 |
磨石生物公司 |
多表位疫苗盒
|