JP2021525076A5 - - Google Patents

Info

Publication number
JP2021525076A5
JP2021525076A5 JP2020565312A JP2020565312A JP2021525076A5 JP 2021525076 A5 JP2021525076 A5 JP 2021525076A5 JP 2020565312 A JP2020565312 A JP 2020565312A JP 2020565312 A JP2020565312 A JP 2020565312A JP 2021525076 A5 JP2021525076 A5 JP 2021525076A5
Authority
JP
Japan
Prior art keywords
sequence
antigen
nucleic acid
mhc class
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020565312A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021525076A (ja
JP7554119B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/033830 external-priority patent/WO2019226941A1/en
Publication of JP2021525076A publication Critical patent/JP2021525076A/ja
Publication of JP2021525076A5 publication Critical patent/JP2021525076A5/ja
Priority to JP2024153547A priority Critical patent/JP2024178211A/ja
Application granted granted Critical
Publication of JP7554119B2 publication Critical patent/JP7554119B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020565312A 2018-05-23 2019-05-23 共有抗原 Active JP7554119B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024153547A JP2024178211A (ja) 2018-05-23 2024-09-06 共有抗原

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862675649P 2018-05-23 2018-05-23
US201862675559P 2018-05-23 2018-05-23
US62/675,649 2018-05-23
US62/675,559 2018-05-23
PCT/US2019/033830 WO2019226941A1 (en) 2018-05-23 2019-05-23 Shared antigens

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024153547A Division JP2024178211A (ja) 2018-05-23 2024-09-06 共有抗原

Publications (3)

Publication Number Publication Date
JP2021525076A JP2021525076A (ja) 2021-09-24
JP2021525076A5 true JP2021525076A5 (enExample) 2022-05-27
JP7554119B2 JP7554119B2 (ja) 2024-09-19

Family

ID=68617213

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020565312A Active JP7554119B2 (ja) 2018-05-23 2019-05-23 共有抗原
JP2024153547A Pending JP2024178211A (ja) 2018-05-23 2024-09-06 共有抗原

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024153547A Pending JP2024178211A (ja) 2018-05-23 2024-09-06 共有抗原

Country Status (10)

Country Link
US (1) US20210196806A1 (enExample)
EP (1) EP3796927A4 (enExample)
JP (2) JP7554119B2 (enExample)
KR (1) KR20210013105A (enExample)
CN (1) CN112368386A (enExample)
AU (2) AU2019275072A1 (enExample)
CA (1) CA3099644A1 (enExample)
IL (1) IL278864B1 (enExample)
TW (1) TW202000907A (enExample)
WO (1) WO2019226941A1 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201501017D0 (en) 2014-12-23 2015-03-04 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers
MA49156A (fr) 2014-12-23 2020-03-25 Immatics Biotechnologies Gmbh Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers
LT3388075T (lt) 2015-03-27 2023-11-10 Immatics Biotechnologies Gmbh Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš įvairius navikus (seq id 25 - mrax5-003)
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
GB201604458D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
EP3634449A4 (en) 2017-05-08 2021-03-17 Gritstone Oncology, Inc. ALPHAVIRUS NEOANTIGEN VECTORS
WO2020037302A1 (en) * 2018-08-17 2020-02-20 Gritstone Oncology, Inc. Antigen-binding proteins targeting shared antigens
TWI852977B (zh) 2019-01-10 2024-08-21 美商健生生物科技公司 前列腺新抗原及其用途
WO2020186064A1 (en) * 2019-03-12 2020-09-17 The General Hospital Corporation Highly networked immunogen composition
MX2021014525A (es) 2019-05-30 2022-03-17 Gritstone Bio Inc Adenovirus modificados.
DE102019114735A1 (de) * 2019-06-02 2020-12-03 PMCR GmbH HLA-Tumorantigenpeptiden der Klasse I und II zur Behandlung von Mamma-/Brustkarzinomen
KR20220098379A (ko) * 2019-11-15 2022-07-12 그릿스톤 바이오, 인코포레이티드 공유 네오항원을 표적으로 하는 항원-결합 단백질
JP2023522512A (ja) * 2019-11-18 2023-05-31 エピヴァックス セラピューティクス インコーポレイテッド 共通のネオエピトープワクチンのための改善された組成物及び方法
CR20220220A (es) 2019-11-18 2022-09-20 Janssen Biotech Inc Vacunas basadas en calr y jak2 mutantes y sus usos
WO2021119545A1 (en) * 2019-12-11 2021-06-17 Gritstone Bio, Inc. Durable vaccination
EP4138890A4 (en) * 2020-04-21 2024-07-31 Gritstone bio, Inc. ANTIGEN CODING CASSETTES
CA3183756A1 (en) 2020-05-19 2021-11-25 Amgen Inc. Mageb2 binding constructs
EP4175664A2 (en) 2020-07-06 2023-05-10 Janssen Biotech, Inc. Prostate neoantigens and their uses
CN116438308A (zh) 2020-08-06 2023-07-14 磨石生物公司 多表位疫苗盒
JP2023541671A (ja) * 2020-09-17 2023-10-03 プロシーナ バイオサイエンシーズ リミテッド シヌクレイノパチーの処置のためのアルファ-シヌクレインワクチン
US11421015B2 (en) 2020-12-07 2022-08-23 Think Therapeutics, Inc. Method of compact peptide vaccines using residue optimization
CN116710115A (zh) 2020-11-20 2023-09-05 思维疗法股份有限公司 用于优化的肽疫苗的组合物和方法
US11058751B1 (en) 2020-11-20 2021-07-13 Think Therapeutics, Inc. Compositions for optimized RAS peptide vaccines
EP4255477A4 (en) * 2020-12-03 2024-11-06 Gritstone bio, Inc. HOMOLOGATED ADENOVIRAL VACCINATION
CN112852841A (zh) * 2021-02-03 2021-05-28 郑州大学 一种高效表达目的蛋白的顺式复制子rna构建体
CN116867799A (zh) * 2021-02-10 2023-10-10 上海吉倍生物技术有限公司 Ras G13D突变体表位肽及识别Ras G13D突变体的T细胞受体
AU2022256469A1 (en) * 2021-04-14 2023-10-12 Academisch Ziekenhuis Leiden Magec2 immunogenic peptides, binding proteins recognizing magec2 immunogenic peptides, and uses thereof
US11464842B1 (en) 2021-04-28 2022-10-11 Think Therapeutics, Inc. Compositions and method for optimized peptide vaccines using residue optimization
WO2022229966A1 (en) 2021-04-29 2022-11-03 Yeda Research And Development Co. Ltd. T cell receptors directed against ras-derived recurrent neoantigens and methods of identifying same
TWI804229B (zh) * 2021-09-27 2023-06-01 美商圖策智能科技有限公司 基於蛋白質突變預測的蛋白質結合自由能估測方法及系統
CN115785206B (zh) * 2022-06-10 2024-03-12 河北博海生物工程开发有限公司 肺癌特异性分子靶标07及其用途
CN115785208B (zh) * 2022-06-10 2024-07-12 河北博海生物工程开发有限公司 肺癌特异性分子靶标01及其用途
CN115785204B (zh) * 2022-06-10 2024-02-13 河北博海生物工程开发有限公司 肺癌特异性分子靶标08及其用途
CN115785205B (zh) * 2022-06-10 2024-08-30 河北博海生物工程开发有限公司 肺癌特异性分子靶标09及其用途
CN115785209B (zh) * 2022-06-10 2024-08-02 河北博海生物工程开发有限公司 肺癌特异性分子靶标06及其用途
CN115785203B (zh) * 2022-06-10 2024-03-12 河北博海生物工程开发有限公司 肺癌特异性分子靶标10及其用途
CN115785207B (zh) * 2022-06-10 2024-08-30 河北博海生物工程开发有限公司 肺癌特异性分子靶标02及其用途
CN115785211B (zh) * 2022-06-10 2024-09-24 河北博海生物工程开发有限公司 肺癌特异性分子靶标04及其用途
WO2024136608A1 (ko) * 2022-12-23 2024-06-27 한미약품 주식회사 복수 kras 변이 펩티드가 연결된 항원 펩티드, 이를 코딩하는 핵산 및 이의 용도
CN116183907B (zh) * 2023-03-09 2025-03-25 巴迪泰(广西)生物科技有限公司 一种基于抗原捕捉磁珠技术的抗原富集与清洗方法及系统
WO2024216073A1 (en) * 2023-04-14 2024-10-17 The Trustees Of Columbia University In The City Of New York Engineered microbes comprising tumor neoantigen vectors for cancer immunotherapy
WO2024254461A2 (en) * 2023-06-07 2024-12-12 Nutech Ventures Methods and compositions for vaccine development and delivery
GB202400424D0 (en) * 2024-01-11 2024-02-28 Cancer Research Tech Ltd Treatment and prevention of lung cancer
CN121464216A (zh) * 2024-01-17 2026-02-03 艾博生物科技(上海)有限公司 用于诱导针对kras突变细胞的抗原特异性免疫的组合物和方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
GB8311018D0 (en) 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US5019369A (en) 1984-10-22 1991-05-28 Vestar, Inc. Method of targeting tumors in humans
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US5240846A (en) 1989-08-22 1993-08-31 The Regents Of The University Of Michigan Gene therapy vector for cystic fibrosis
US5279833A (en) 1990-04-04 1994-01-18 Yale University Liposomal transfection of nucleic acids into animal cells
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
PT728214E (pt) 1993-11-09 2004-11-30 Ohio Med College Linhas celulares estaveis capazes de expressar o gene de replicacao do virus adeno-associado
DE69534166T2 (de) 1994-10-28 2006-03-09 Trustees Of The University Of Pennsylvania Rekombinanter adenovirus und methoden zu dessen verwendung
US5792462A (en) * 1995-05-23 1998-08-11 University Of North Carolina At Chapel Hill Alphavirus RNA replicon systems
US5849589A (en) 1996-03-11 1998-12-15 Duke University Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells
ES2180045T3 (es) * 1996-04-19 2003-02-01 Us Gov Sec Health Peptidos ras mutados para la generacion de linfocitos t citotoxicos cd8+.
WO1998010087A1 (en) 1996-09-06 1998-03-12 Trustees Of The University Of Pennsylvania Chimpanzee adenovirus vectors
US7462354B2 (en) * 1999-12-28 2008-12-09 Pharmexa Inc. Method and system for optimizing minigenes and peptides encoded thereby
US20040248113A1 (en) * 1999-12-28 2004-12-09 Alessandro Sette Method and system for optimizing multi-epitope nucleic acid constructs and peptides encoded thereby
EP1242108B1 (en) 1999-12-28 2007-07-11 Pharmexa Inc. Optimized minigenes and peptides encoded thereby
WO2001055393A2 (en) * 2000-01-28 2001-08-02 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Mhc class ii restricted t cell epitopes from the cancer antigen ny-eso-1
CA2500955A1 (en) 2002-10-03 2004-04-15 Genencor International, Inc. Optimized multi-epitope constructs and uses thereof
WO2005033265A2 (en) * 2003-04-25 2005-04-14 Epimmune Inc. Optimized multi-epitope constructs and uses thereof
DE602005017743D1 (de) * 2004-01-23 2009-12-31 Angeletti P Ist Richerche Bio Impfstoffträger für schimpansen-adenovirus
US7332322B2 (en) * 2004-09-14 2008-02-19 Ilya Frolov Venezuelan equine encephalitis virus replicons with adaptive mutations in the genome and uses thereof
US7220549B2 (en) 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US7283337B2 (en) 2005-03-04 2007-10-16 Headway Technologies, Inc. Abutted exchange bias design for sensor stabilization
CN101579528B (zh) * 2009-06-24 2011-06-29 中国人民解放军军事医学科学院军事兽医研究所 一种hiv复合多表位dna疫苗及其应用
EP2569633B1 (en) 2010-05-14 2016-02-10 The General Hospital Corporation Compositions and methods of identifying tumor specific neoantigens
KR102759126B1 (ko) 2010-12-30 2025-01-24 파운데이션 메디신 인코포레이티드 종양 샘플의 다유전자 분석의 최적화
TWI636065B (zh) * 2013-08-05 2018-09-21 伊瑪提克斯生物科技有限公司 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物
IL294183B2 (en) * 2015-05-20 2023-10-01 Dana Farber Cancer Inst Inc shared neoantigens
ES2970865T3 (es) * 2015-12-16 2024-05-31 Gritstone Bio Inc Identificación, fabricación y uso de neoantígenos
SG11201811442UA (en) * 2016-06-20 2019-01-30 Isa Pharmaceuticals B V Formulation of a peptide vaccine
JP2020500552A (ja) * 2016-11-23 2020-01-16 グリットストーン オンコロジー インコーポレイテッド 新生抗原のウイルスによる送達方法
GB201621732D0 (en) * 2016-12-20 2017-02-01 Agricultural Research Council A multi-epitope dna vaccine for heartwater
CA3060569A1 (en) 2017-04-19 2018-10-25 Gritstone Oncology, Inc. Neoantigen identification, manufacture, and use
EP3634449A4 (en) 2017-05-08 2021-03-17 Gritstone Oncology, Inc. ALPHAVIRUS NEOANTIGEN VECTORS
AU2018279627B2 (en) * 2017-06-09 2023-08-10 Seattle Project Corp. Neoantigen identification, manufacture, and use

Similar Documents

Publication Publication Date Title
JP2021525076A5 (enExample)
JP2023526495A5 (enExample)
JP2022512912A5 (enExample)
JP2023541108A5 (enExample)
JP2022539417A5 (enExample)
JP2021524247A5 (enExample)
EP3177720B1 (en) Virus like particle comprising modified envelope protein e3
US20230270841A1 (en) Coronavirus vaccine
JP2023523414A5 (enExample)
JP2022534282A5 (enExample)
RU2019119272A (ru) Вирусная доставка неоантигенов
JP2021525076A (ja) 共有抗原
JP2021524247A (ja) 免疫チェックポイント阻害剤の共発現ベクター
EP3423473A2 (en) Virus vectors expressing multiple epitopes of tumor associated antigens for inducing antitumor immunity
JP2022512912A (ja) アルファウイルス新生抗原ベクター及びインターフェロン阻害因子
JP2023523413A5 (enExample)
JP2023521662A5 (enExample)
Lundstrom Alphavirus vectors for vaccine production and gene therapy
CN111630060A (zh) 用于在疾病的预防和/或治疗中使用的疫苗
BR112015023524B1 (pt) Vírus vaccinia ankara modificado, composição compreendendo o dito vírus e uso do mesmo para primagem ou reforço de uma resposta imune
CN116096409A (zh) 编码稳定化的冠状病毒刺突蛋白的rna复制子
JP2004501646A5 (enExample)
CN106459997A (zh) 用于疫苗应用的高效价病毒样囊泡的进化
JP2024510610A (ja) 人工アルファウイルス由来rnaレプリコン発現系
JP2020532287A (ja) 癌の治療のためのネオアンチゲンワクチン組成物