JP2022516401A - Ｉｒａｋ分解剤およびそれらの使用 - Google Patents
Ｉｒａｋ分解剤およびそれらの使用 Download PDFInfo
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| CA3116347A1 (en) | 2018-10-31 | 2020-05-07 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity |
| US11352350B2 (en) | 2018-11-30 | 2022-06-07 | Kymera Therapeutics, Inc. | IRAK degraders and uses thereof |
| MA55565A (fr) | 2019-04-05 | 2022-02-09 | Kymera Therapeutics Inc | Agents de dégradation de stat et leurs utilisations |
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| EP4076524A4 (en) | 2019-12-17 | 2023-11-29 | Kymera Therapeutics, Inc. | IRAQ DEGRADERS AND USES THEREOF |
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| US11857535B2 (en) | 2020-07-30 | 2024-01-02 | Kymera Therapeutics, Inc. | Methods of treating mutant lymphomas |
| CN113512025B (zh) * | 2020-07-31 | 2023-01-06 | 四川大学 | 一种吲唑酯类化合物及其制药用途 |
| KR20230050375A (ko) | 2020-08-05 | 2023-04-14 | 상하이 리딩택 파마슈티컬 코., 엘티디. | 단백질 표적화 및 분해용 화합물, 이의 제조방법 및 용도 |
| WO2022088551A1 (zh) | 2020-10-26 | 2022-05-05 | 上海领泰生物医药科技有限公司 | 吲唑类衍生物及其制备方法和应用 |
| KR20230143632A (ko) * | 2020-12-30 | 2023-10-12 | 카이메라 쎄라퓨틱스 인코포레이티드 | Irak 분해제 및 이의 용도 |
| CN116648248A (zh) * | 2021-01-26 | 2023-08-25 | 成都茵创园医药科技有限公司 | 芳香化合物、含其的药物组合物及其应用 |
| EP4291187A1 (en) * | 2021-02-15 | 2023-12-20 | Kymera Therapeutics, Inc. | Irak4 degraders and uses thereof |
| KR20230145446A (ko) * | 2021-02-15 | 2023-10-17 | 카이메라 쎄라퓨틱스 인코포레이티드 | Irak4 분해제 및 이의 용도 |
| IL307465A (en) * | 2021-04-08 | 2023-12-01 | Curis Inc | Combined therapies for cancer treatment |
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| CN115504963A (zh) * | 2021-06-22 | 2022-12-23 | 苏州开拓药业股份有限公司 | 一种c-Myc蛋白降解剂 |
| TW202321219A (zh) | 2021-08-11 | 2023-06-01 | 大陸商四川海思科製藥有限公司 | 雜環衍生物及其組合物和藥學上的應用 |
| AU2022334530A1 (en) | 2021-08-23 | 2024-04-04 | Shanghai Leadingtac Pharmaceutical Co. Ltd. | Irak4 degradation agent, and preparation method therefor and use thereof |
| CN115772180A (zh) * | 2021-09-08 | 2023-03-10 | 南京明德新药研发有限公司 | 戊二酰亚胺类化合物与其应用 |
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| AR127505A1 (es) * | 2021-10-29 | 2024-01-31 | Kymera Therapeutics Inc | Degradadores irak-4 y síntesis de los mismos |
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| TW202333670A (zh) * | 2022-01-04 | 2023-09-01 | 大陸商海思科醫藥集團股份有限公司 | 抑制並降解irak4的化合物及其藥物组合物和藥學上的應用 |
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| US20210323952A1 (en) | 2021-10-21 |
| US11807636B2 (en) | 2023-11-07 |
| CN113423427A (zh) | 2021-09-21 |
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