JP2021521192A - セレブロンリガンドおよび同リガンドを含む二機能性化合物 - Google Patents

セレブロンリガンドおよび同リガンドを含む二機能性化合物 Download PDF

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JP2021521192A
JP2021521192A JP2020555835A JP2020555835A JP2021521192A JP 2021521192 A JP2021521192 A JP 2021521192A JP 2020555835 A JP2020555835 A JP 2020555835A JP 2020555835 A JP2020555835 A JP 2020555835A JP 2021521192 A JP2021521192 A JP 2021521192A
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syndrome
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optionally substituted
disease
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JP2021521192A5 (https=
JPWO2019199816A5 (https=
Inventor
アンドリュー ピー． クルー，
アンドリュー ピー． クルー，
クレイグ エム． クルーズ，
クレイグ エム． クルーズ，
ハンチン ドン，
ハンチン ドン，
キース アール． ホーンバーガー，
キース アール． ホーンバーガー，
ジン ワン，
ジン ワン，
イミン チアン，
イミン チアン，
カート ジマーマン，
カート ジマーマン，
マイケル バーリン，
マイケル バーリン，
ローレンス ビー． スナイダー，
ローレンス ビー． スナイダー，
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Arvinas Operations Inc
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Arvinas Operations Inc
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Priority claimed from US15/953,108 external-priority patent/US20180228907A1/en
Application filed by Arvinas Operations Inc filed Critical Arvinas Operations Inc
Publication of JP2021521192A publication Critical patent/JP2021521192A/ja
Publication of JP2021521192A5 publication Critical patent/JP2021521192A5/ja
Publication of JPWO2019199816A5 publication Critical patent/JPWO2019199816A5/ja
Priority to JP2023174374A priority Critical patent/JP7748432B2/ja
Priority to JP2025156045A priority patent/JP2025186428A/ja
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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JP2020555835A 2018-04-13 2019-04-09 セレブロンリガンドおよび同リガンドを含む二機能性化合物 Pending JP2021521192A (ja)

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JP2023174374A JP7748432B2 (ja) 2018-04-13 2023-10-06 セレブロンリガンドおよび同リガンドを含む二機能性化合物
JP2025156045A JP2025186428A (ja) 2018-04-13 2025-09-19 セレブロンリガンドおよび同リガンドを含む二機能性化合物

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US15/953,108 US20180228907A1 (en) 2014-04-14 2018-04-13 Cereblon ligands and bifunctional compounds comprising the same
US15/953,108 2018-04-13
PCT/US2019/026570 WO2019199816A1 (en) 2018-04-13 2019-04-09 Cereblon ligands and bifunctional compounds comprising the same

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JP2021521192A5 JP2021521192A5 (https=) 2022-04-18
JPWO2019199816A5 JPWO2019199816A5 (https=) 2022-04-18

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JP2023174374A Active JP7748432B2 (ja) 2018-04-13 2023-10-06 セレブロンリガンドおよび同リガンドを含む二機能性化合物
JP2025156045A Pending JP2025186428A (ja) 2018-04-13 2025-09-19 セレブロンリガンドおよび同リガンドを含む二機能性化合物

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JP2025156045A Pending JP2025186428A (ja) 2018-04-13 2025-09-19 セレブロンリガンドおよび同リガンドを含む二機能性化合物

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EP (1) EP3774772A1 (https=)
JP (3) JP2021521192A (https=)
KR (1) KR20210003804A (https=)
CN (2) CN118480030A (https=)
AU (3) AU2019251223A1 (https=)
CA (1) CA3095912A1 (https=)
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