JP2020502070A5 - - Google Patents

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JP2020502070A5
JP2020502070A5 JP2019528506A JP2019528506A JP2020502070A5 JP 2020502070 A5 JP2020502070 A5 JP 2020502070A5 JP 2019528506 A JP2019528506 A JP 2019528506A JP 2019528506 A JP2019528506 A JP 2019528506A JP 2020502070 A5 JP2020502070 A5 JP 2020502070A5
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refractory
disease
syndrome
corticosteroid
dermatomyositis
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JP2019528506A
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JP2020502070A (ja
JP7595413B2 (ja
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Priority claimed from PCT/US2017/063959 external-priority patent/WO2018102552A1/en
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JP2019528506A 2016-11-30 2017-11-30 15-pgdh阻害剤とコルチコステロイドおよび/またはtnf阻害剤との組み合わせならびにその使用 Active JP7595413B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662428259P 2016-11-30 2016-11-30
US62/428,259 2016-11-30
US201762510166P 2017-05-23 2017-05-23
US62/510,166 2017-05-23
PCT/US2017/063959 WO2018102552A1 (en) 2016-11-30 2017-11-30 Combinations of 15-pgdh inhibitors with corcosteroids and/or tnf inhibitors and uses thereof

Publications (3)

Publication Number Publication Date
JP2020502070A JP2020502070A (ja) 2020-01-23
JP2020502070A5 true JP2020502070A5 (https=) 2021-01-28
JP7595413B2 JP7595413B2 (ja) 2024-12-06

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JP2019528506A Active JP7595413B2 (ja) 2016-11-30 2017-11-30 15-pgdh阻害剤とコルチコステロイドおよび/またはtnf阻害剤との組み合わせならびにその使用

Country Status (4)

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US (2) US11690847B2 (https=)
EP (1) EP3548035A4 (https=)
JP (1) JP7595413B2 (https=)
WO (1) WO2018102552A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11690847B2 (en) 2016-11-30 2023-07-04 Case Western Reserve University Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof
US11718589B2 (en) 2017-02-06 2023-08-08 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase
US12336982B2 (en) 2018-11-21 2025-06-24 Rodeo Therapeutics Corporation Compositions and methods of modulating short-chain dehydrogenase activity
US12616681B2 (en) 2022-08-22 2026-05-05 Case Western Reserve University Compositions and methods for treating renal injury

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AU2014342811B2 (en) 2013-10-15 2019-01-03 Board Of Regents Of The University Of Texas System Compositions and methods of modulating short-chain dehydrogenase activity
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CN107921025A (zh) 2015-03-08 2018-04-17 卡斯西部储备大学 用于治疗纤维症的短链脱氢酶活性的抑制剂
WO2018187810A1 (en) 2017-04-07 2018-10-11 Case Western Reserve University Inhibitors of short-chain dehydrogenase activity for treating coronary disorders
US20220023266A1 (en) 2018-12-07 2022-01-27 Neurocrine Biosciences, Inc. Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia
TWI834795B (zh) * 2019-01-08 2024-03-11 日商杏林製藥股份有限公司 15-pgdh抑制劑
JP7623365B2 (ja) 2019-09-27 2025-01-28 ニューロクライン バイオサイエンシーズ,インコーポレイテッド Crf受容体アンタゴニストおよび使用方法
KR20220146458A (ko) 2020-01-23 2022-11-01 마이오포르테 테라퓨틱스 인코포레이티드 Pgdh 억제제 및 그의 제조 및 사용 방법
AU2021275122A1 (en) 2020-05-20 2022-12-15 Board Of Regents Of The University Of Texas System Compositions and methods of modulating short-chain dehydrogenase activity
CA3200394A1 (en) * 2020-12-09 2022-06-16 Helen M. Blau Inhibition of prostaglandin degrading enzyme 15-pgdh to improve joint structure and function
WO2025148611A1 (zh) * 2024-01-12 2025-07-17 新牛(郑州)生物科技有限公司 肿瘤抗原肽融合蛋白及其组合物的基因工程化递送和应用

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