JP2020125349A5 - - Google Patents
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- JP2020125349A5 JP2020125349A5 JP2020081156A JP2020081156A JP2020125349A5 JP 2020125349 A5 JP2020125349 A5 JP 2020125349A5 JP 2020081156 A JP2020081156 A JP 2020081156A JP 2020081156 A JP2020081156 A JP 2020081156A JP 2020125349 A5 JP2020125349 A5 JP 2020125349A5
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- lymphoma
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- cancer
- leukemia
- agents
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- 206010028980 Neoplasm Diseases 0.000 claims 26
- 201000011510 cancer Diseases 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 11
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 150000003839 salts Chemical class 0.000 claims 10
- 206010025323 Lymphomas Diseases 0.000 claims 8
- 208000024891 symptom Diseases 0.000 claims 7
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- 229960005486 vaccine Drugs 0.000 claims 5
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 4
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- 125000000582 cycloheptyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1419570.5A GB201419570D0 (en) | 2014-11-03 | 2014-11-03 | Pharmaceutical compound |
| GB1419570.5 | 2014-11-03 | ||
| GBGB1507883.5A GB201507883D0 (en) | 2015-05-08 | 2015-05-08 | Pharmaceutical compound |
| GB1507883.5 | 2015-05-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017542315A Division JP6701214B2 (ja) | 2014-11-03 | 2015-11-02 | 医薬化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020125349A JP2020125349A (ja) | 2020-08-20 |
| JP2020125349A5 true JP2020125349A5 (https=) | 2020-10-15 |
| JP6994538B2 JP6994538B2 (ja) | 2022-01-14 |
Family
ID=54476948
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017542315A Active JP6701214B2 (ja) | 2014-11-03 | 2015-11-02 | 医薬化合物 |
| JP2020081156A Active JP6994538B2 (ja) | 2014-11-03 | 2020-05-01 | 医薬化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017542315A Active JP6701214B2 (ja) | 2014-11-03 | 2015-11-02 | 医薬化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10590086B2 (https=) |
| EP (1) | EP3215156B1 (https=) |
| JP (2) | JP6701214B2 (https=) |
| KR (1) | KR102602947B1 (https=) |
| CN (2) | CN107108556B (https=) |
| AU (1) | AU2015341913B2 (https=) |
| CA (1) | CA2965741C (https=) |
| ES (1) | ES3055013T3 (https=) |
| MX (1) | MX390081B (https=) |
| RU (1) | RU2719446C2 (https=) |
| WO (1) | WO2016071293A2 (https=) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20131167T1 (hr) | 2007-06-18 | 2014-01-03 | Merck Sharp & Dohme B.V. | Antitijela za humani receptor programirane smrti pd-1 |
| RU2719446C2 (ru) * | 2014-11-03 | 2020-04-17 | Айомет Фарма Лтд | Фармацевтическое соединение |
| JO3637B1 (ar) | 2015-04-28 | 2020-08-27 | Janssen Sciences Ireland Uc | مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv |
| EA201792573A1 (ru) | 2015-05-21 | 2018-04-30 | Харпун Терапьютикс, Инк. | Триспецифические связанные белки и способы их применения |
| CA3005766A1 (en) | 2015-12-17 | 2017-06-22 | Merck Patent Gmbh | Polycyclic tlr7/8 antagonists and use thereof in the treatment of immune disorders |
| CN107840826B (zh) * | 2016-09-19 | 2021-07-09 | 西华大学 | 1h-吲唑类衍生物及其作为ido抑制剂的用途 |
| CN107619392B (zh) * | 2016-07-15 | 2021-01-01 | 西华大学 | 1h-吲唑-4-醚类化合物及其作为ido抑制剂的用途 |
| CN107033087B (zh) * | 2016-02-04 | 2020-09-04 | 西华大学 | 1h-吲唑-4-胺类化合物及其作为ido抑制剂的用途 |
| WO2017133258A1 (zh) * | 2016-02-04 | 2017-08-10 | 西华大学 | 1h-吲唑类衍生物及其作为ido抑制剂的用途 |
| BR112018071602B1 (pt) | 2016-04-29 | 2024-02-27 | Iomet Pharma Ltd. | Compostos de imidazopiridina substituídos, sua composição e seus usos como inibidores da indolamina 2,3-dioxigenase e/ou triptofano-2,3- dioxigenase |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| CN107556244B (zh) * | 2016-07-01 | 2021-09-03 | 上海迪诺医药科技有限公司 | 并环化合物、其药物组合物及应用 |
| EP3269714A1 (en) | 2016-07-13 | 2018-01-17 | Netherlands Translational Research Center B.V. | Inhibitors of tryptophan 2,3-dioxygenase |
| CN107674029A (zh) * | 2016-08-02 | 2018-02-09 | 上海迪诺医药科技有限公司 | 多环化合物、其药物组合物及应用 |
| JP7125385B2 (ja) | 2016-08-08 | 2022-08-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｔｌｒ７／８アンタゴニストおよびそれらの使用 |
| EP3505517A4 (en) * | 2016-08-23 | 2020-01-15 | Beijing InnoCare Pharma Tech Co., Ltd. | Fused heterocyclic derivative, preparation method therefor and medical use thereof |
| TW201815766A (zh) | 2016-09-22 | 2018-05-01 | 美商普雷辛肯公司 | 用於ｉｄｏ及ｔｄｏ調節之化合物及方法以及其適應症 |
| EP3515914A4 (en) * | 2016-09-24 | 2020-04-15 | BeiGene, Ltd. | INNOVATIVE 5- OR 8-SUBSTITUTED IMIDAZO [1,5-A] PYRIDINE AS SELECTIVE INHIBITORS OF INDOLEAMINE AND / OR TRYPTOPHANE-2,3-DIOXYGENASES |
| WO2018078360A1 (en) * | 2016-10-26 | 2018-05-03 | E-Therapeutics Plc | Modulators of hedgehog (hh) signalling pathway |
| JP2020506895A (ja) | 2017-01-17 | 2020-03-05 | ボード オブ レジェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | インドールアミン２，３−ジオキシゲナーゼおよび／またはトリプトファンジオキシゲナーゼの阻害剤として有用な化合物 |
| KR102294129B1 (ko) * | 2017-03-16 | 2021-08-27 | 국제약품 주식회사 | N-벤질-n-페녹시카르보닐-페닐설폰아마이드 유도체 및 그를 포함하는 약제학적 조성물 |
| CN108689938B (zh) * | 2017-04-10 | 2021-07-30 | 西华大学 | 多取代的吲唑类化合物及其作为ido抑制剂的用途 |
| CN108689937B (zh) * | 2017-04-10 | 2021-09-17 | 西华大学 | 吲唑类化合物及其在制备ido抑制剂类药物上的用途 |
| CN108689936B (zh) * | 2017-04-10 | 2021-09-10 | 西华大学 | 含氮取代基的吲唑类化合物及其作为ido抑制剂的用途 |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| AU2018265856B2 (en) | 2017-05-12 | 2023-04-27 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
| US20210340250A1 (en) | 2017-05-30 | 2021-11-04 | Bristol-Myers Squibb Company | Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent |
| US10906924B2 (en) | 2017-06-28 | 2021-02-02 | Glaxosmithkline Intellectual Property Development Limited | Modulators of indoleamine 2,3-dioxygenase |
| MY200629A (en) | 2017-08-01 | 2024-01-06 | Theravance Biopharma R&D Ip Llc | Pyrazolo and triazolo bicyclic compounds as jak kinase inhibitors |
| HRP20241268T1 (hr) | 2017-10-13 | 2024-12-06 | Harpoon Therapeutics, Inc. | Trispecifični proteini i postupci primjene |
| IL315737A (en) | 2017-10-13 | 2024-11-01 | Harpoon Therapeutics Inc | B-cell maturation antigen-binding proteins |
| WO2019078246A1 (ja) | 2017-10-19 | 2019-04-25 | 一般社団法人ファルマバレープロジェクト支援機構 | Ｉｄｏ／ｔｄｏ阻害剤 |
| JP7301390B2 (ja) * | 2017-10-19 | 2023-07-03 | ジェイエス・イノファーム・（シャンハイ）・リミテッド | ヘテロ環式化合物、ヘテロ環式化合物を含む組成物、及びその使用方法 |
| US11759461B2 (en) | 2017-10-30 | 2023-09-19 | The Scripps Research Institute | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types |
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