ES3055013T3 - Inhibitors of tryptophan-2,3-dioxygenase or indoleamine-2,3-dioxygenase - Google Patents

Inhibitors of tryptophan-2,3-dioxygenase or indoleamine-2,3-dioxygenase

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Publication number
ES3055013T3
ES3055013T3 ES15790910T ES15790910T ES3055013T3 ES 3055013 T3 ES3055013 T3 ES 3055013T3 ES 15790910 T ES15790910 T ES 15790910T ES 15790910 T ES15790910 T ES 15790910T ES 3055013 T3 ES3055013 T3 ES 3055013T3
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ES
Spain
Prior art keywords
dioxygenase
indoleamine
tryptophan
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15790910T
Other languages
English (en)
Inventor
Phillip Cowley
Alan Wise
Susan Davis
Michael Kiczun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iomet Pharma Ltd
Original Assignee
Iomet Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1419570.5A external-priority patent/GB201419570D0/en
Priority claimed from GBGB1507883.5A external-priority patent/GB201507883D0/en
Application filed by Iomet Pharma Ltd filed Critical Iomet Pharma Ltd
Application granted granted Critical
Publication of ES3055013T3 publication Critical patent/ES3055013T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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