SG11202006141RA - Cycloalkyl substituted pyrazolopyrimidines having activity against rsv - Google Patents

Cycloalkyl substituted pyrazolopyrimidines having activity against rsv

Info

Publication number
SG11202006141RA
SG11202006141RA SG11202006141RA SG11202006141RA SG11202006141RA SG 11202006141R A SG11202006141R A SG 11202006141RA SG 11202006141R A SG11202006141R A SG 11202006141RA SG 11202006141R A SG11202006141R A SG 11202006141RA SG 11202006141R A SG11202006141R A SG 11202006141RA
Authority
SG
Singapore
Prior art keywords
activity against
cycloalkyl substituted
against rsv
substituted pyrazolopyrimidines
pyrazolopyrimidines
Prior art date
Application number
SG11202006141RA
Inventor
David Francis Alain Lançois
Jérôme Émile Georges Guillemont
Pierre Jean-Marie Bernard Raboisson
Dirk André Emmy Roymans
Peter Rigaux
Antoine Benjamin Michaut
Original Assignee
Janssen Sciences Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Unlimited Co filed Critical Janssen Sciences Ireland Unlimited Co
Publication of SG11202006141RA publication Critical patent/SG11202006141RA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11202006141RA 2018-01-31 2019-01-30 Cycloalkyl substituted pyrazolopyrimidines having activity against rsv SG11202006141RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18154314 2018-01-31
PCT/EP2019/052209 WO2019149734A1 (en) 2018-01-31 2019-01-30 Cycloalkyl substituted pyrazolopyrimidines having activity against rsv

Publications (1)

Publication Number Publication Date
SG11202006141RA true SG11202006141RA (en) 2020-07-29

Family

ID=61132085

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202006141RA SG11202006141RA (en) 2018-01-31 2019-01-30 Cycloalkyl substituted pyrazolopyrimidines having activity against rsv

Country Status (11)

Country Link
US (1) US11491157B2 (en)
EP (1) EP3746444B1 (en)
JP (1) JP7305658B2 (en)
KR (1) KR20200116099A (en)
CN (1) CN111670189A (en)
AU (1) AU2019216260B2 (en)
CA (1) CA3087926A1 (en)
EA (1) EA202091835A1 (en)
MX (1) MX2020008061A (en)
SG (1) SG11202006141RA (en)
WO (1) WO2019149734A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202091835A1 (en) 2018-01-31 2020-10-20 Янссен Сайенсиз Айрлэнд Анлимитед Компани CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES WITH AN ACTIVITY AGAINST RSV
AU2019260109B2 (en) 2018-04-23 2023-07-13 Janssen Sciences Ireland Unlimited Company Heteroaromatic compounds having activity against RSV

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Also Published As

Publication number Publication date
US11491157B2 (en) 2022-11-08
EA202091835A1 (en) 2020-10-20
AU2019216260B2 (en) 2023-03-02
KR20200116099A (en) 2020-10-08
WO2019149734A1 (en) 2019-08-08
EP3746444B1 (en) 2023-09-27
US20200360387A1 (en) 2020-11-19
CN111670189A (en) 2020-09-15
MX2020008061A (en) 2020-09-09
EP3746444A1 (en) 2020-12-09
CA3087926A1 (en) 2019-08-08
JP7305658B2 (en) 2023-07-10
JP2021514347A (en) 2021-06-10
AU2019216260A1 (en) 2020-07-02

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