|
WO2006110689A2
(en)
*
|
2005-04-07 |
2006-10-19 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an aav vector
|
|
US9255154B2
(en)
|
2012-05-08 |
2016-02-09 |
Alderbio Holdings, Llc |
Anti-PCSK9 antibodies and use thereof
|
|
KR20240090694A
(ko)
*
|
2013-07-22 |
2024-06-21 |
더 칠드런스 호스피탈 오브 필라델피아 |
변종 aav 및 조성물, 세포, 기관 및 조직으로의 유전자 전이를 위한 방법 및 용도
|
|
ES2744565T3
(es)
|
2014-04-25 |
2020-02-25 |
Genethon |
Tratamiento de la hiperbilirrubinemia
|
|
WO2015191508A1
(en)
|
2014-06-09 |
2015-12-17 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
SG11201703148TA
(en)
|
2014-11-05 |
2017-05-30 |
Voyager Therapeutics Inc |
Aadc polynucleotides for the treatment of parkinson's disease
|
|
GB201420139D0
(en)
|
2014-11-12 |
2014-12-24 |
Ucl Business Plc |
Factor IX gene therapy
|
|
CA3193811A1
(en)
|
2014-11-14 |
2016-05-19 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
CN119876138A
(zh)
|
2014-11-14 |
2025-04-25 |
沃雅戈治疗公司 |
调节性多核苷酸
|
|
HK1245326A1
(zh)
|
2014-12-12 |
2018-08-24 |
Voyager Therapeutics, Inc. |
用於生产scaav的组合物和方法
|
|
US10081659B2
(en)
|
2015-04-06 |
2018-09-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Adeno-associated vectors for enhanced transduction and reduced immunogenicity
|
|
GB201508026D0
(en)
|
2015-05-11 |
2015-06-24 |
Ucl Business Plc |
Capsid
|
|
WO2016183422A1
(en)
*
|
2015-05-14 |
2016-11-17 |
St. Jude Children's Research Hospital, Inc. |
Nucleic acid molecules containing spacers and methods of use thereof
|
|
WO2016210170A1
(en)
*
|
2015-06-23 |
2016-12-29 |
The Children's Hospital Of Philadelphia |
Modified factor ix, and compositions, methods and uses for gene transfer to cells, organs and tissues
|
|
BR112018003665A2
(en)
|
2015-09-28 |
2018-09-25 |
The University Of North Carolina At Chapel Hill |
methods and compositions for antibody evasion viral vectors
|
|
PE20231949A1
(es)
*
|
2015-10-30 |
2023-12-05 |
Spark Therapeutics Inc |
VARIANTES DEL FACTOR VIII REDUCIDO CON CpG, COMPOSICIONES Y METODOS Y USOS PARA EL TRATAMIENTO DE TRASTORNOS DE LA HEMOSTASIA
|
|
RU2021102893A
(ru)
|
2015-11-05 |
2021-03-03 |
Бамбу Терапьютикс, Инк. |
Модифицированные гены атаксии фридрейха и векторы для генной терапии
|
|
AU2016362317B2
(en)
*
|
2015-12-01 |
2023-03-16 |
Spark Therapeutics, Inc. |
Scalable methods for producing recombinant Adeno-Associated Viral (AAV) vector in serum-free suspension cell culture system suitable for clinical use
|
|
WO2017096162A1
(en)
|
2015-12-02 |
2017-06-08 |
Voyager Therapeutics, Inc. |
Assays for the detection of aav neutralizing antibodies
|
|
US10385320B2
(en)
|
2015-12-02 |
2019-08-20 |
The Board Of Trustees Of The Leland Stanford Junior University |
Recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism
|
|
US10406244B2
(en)
|
2015-12-02 |
2019-09-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
AAV vectors with expanded packaging capacity
|
|
CA3007330A1
(en)
|
2015-12-14 |
2017-06-22 |
The Trustees Of The University Of Pennsylvania |
Composition for treatment of crigler-najjar syndrome
|
|
US20180363000A1
(en)
*
|
2015-12-14 |
2018-12-20 |
The Trustees Of The University Of Pennsylvania |
Aav-anti pcsk9 antibody constructs and uses thereof
|
|
US10179176B2
(en)
|
2016-02-16 |
2019-01-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Recombinant adeno-associated virus capsids resistant to pre-existing human neutralizing antibodies
|
|
MX2018011928A
(es)
*
|
2016-03-30 |
2019-03-28 |
Spark Therapeutics Inc |
Linea celular para produccion de proteina recombinante y/o vector viral.
|
|
EP3448987A4
(en)
|
2016-04-29 |
2020-05-27 |
Voyager Therapeutics, Inc. |
COMPOSITIONS FOR TREATING A DISEASE
|
|
EP3448874A4
(en)
|
2016-04-29 |
2020-04-22 |
Voyager Therapeutics, Inc. |
COMPOSITIONS FOR TREATING A DISEASE
|
|
CA3024448C
(en)
|
2016-05-18 |
2025-09-09 |
Voyager Therapeutics, Inc. |
MODULATING POLYNUCLEOTIDES
|
|
CA3024449A1
(en)
|
2016-05-18 |
2017-11-23 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating huntington's disease
|
|
CA2971303C
(en)
|
2016-06-21 |
2026-03-03 |
Bamboo Therapeutics, Inc. |
Optimized mini-dystrophin genes and expression cassettes and their use
|
|
PE20190401A1
(es)
|
2016-07-26 |
2019-03-13 |
Biomarin Pharm Inc |
Novedosas proteinas de la capside del virus adenoasociado
|
|
WO2018044933A1
(en)
|
2016-08-30 |
2018-03-08 |
The Regents Of The University Of California |
Methods for biomedical targeting and delivery and devices and systems for practicing the same
|
|
EP3293260A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
MX2019002842A
(es)
|
2016-09-12 |
2019-08-29 |
Genethon |
Variantes de alfa-glucosidasa acida y usos de las mismas.
|
|
EP3293203A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
EP3293259A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
EP3534892A4
(en)
*
|
2016-11-04 |
2020-05-27 |
The Children's Hospital of Philadelphia |
GENE TRANSFER COMPOSITIONS, METHODS AND USE FOR TREATING NEURODEGENERATIVE DISEASES
|
|
US20230190958A1
(en)
|
2017-01-13 |
2023-06-22 |
Jichi Medical University |
AAV Vector for Disrupting Coagulation Factor-Related Gene on Liver Genome
|
|
US11541131B2
(en)
|
2017-03-10 |
2023-01-03 |
Genethon |
Treatment of glycogen storage disease III
|
|
US10550405B2
(en)
|
2017-03-15 |
2020-02-04 |
The University Of North Carolina At Chapel Hill |
Rational polyploid adeno-associated virus vectors and methods of making and using the same
|
|
CN110770346B
(zh)
*
|
2017-03-15 |
2024-01-12 |
北卡罗来纳-查佩尔山大学 |
多倍体腺相关病毒载体及其制备和使用方法
|
|
JP2020518259A
(ja)
|
2017-05-05 |
2020-06-25 |
ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. |
ハンチントン病治療組成物および方法
|
|
EP3618839A4
(en)
|
2017-05-05 |
2021-06-09 |
Voyager Therapeutics, Inc. |
COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
|
|
US20200172927A1
(en)
*
|
2017-05-15 |
2020-06-04 |
The Trustees Of Columbia University In The City Of New York |
Reprogramming metabolism by inhibiting vhl for treatment of neurodegeneration
|
|
AU2018281306B2
(en)
|
2017-06-07 |
2025-04-17 |
Spark Therapeutics, Inc. |
Enhancing agents for improved cell transfection and/or rAAV vector production
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
US20210228738A1
(en)
|
2017-07-17 |
2021-07-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
|
|
MX2020000713A
(es)
*
|
2017-07-17 |
2020-08-31 |
Spark Therapeutics Inc |
Metodos de aferesis y sus usos.
|
|
JP7229989B2
(ja)
|
2017-07-17 |
2023-02-28 |
ボイジャー セラピューティクス インコーポレイテッド |
軌道アレイガイドシステム
|
|
MX2020002148A
(es)
*
|
2017-08-25 |
2020-07-20 |
Ovid Therapeutics Inc |
Vectores adenoasociados recombinantes.
|
|
US20200263199A1
(en)
|
2017-09-29 |
2020-08-20 |
Voyager Therapeutics, Inc. |
Rescue of central and peripheral neurological phenotype of friedreich's ataxia by intravenous delivery
|
|
WO2019079242A1
(en)
|
2017-10-16 |
2019-04-25 |
Voyager Therapeutics, Inc. |
TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
|
|
TW202413649A
(zh)
|
2017-10-16 |
2024-04-01 |
美商航海家醫療公司 |
肌萎縮性脊髓側索硬化症(als)之治療
|
|
JP7569216B2
(ja)
|
2018-01-17 |
2024-10-17 |
アドリーナス セラピューティクス, インコーポレイテッド |
21-ヒドロキシラーゼ欠損症のためのアデノ随伴ウイルス遺伝子療法
|
|
US10610606B2
(en)
|
2018-02-01 |
2020-04-07 |
Homology Medicines, Inc. |
Adeno-associated virus compositions for PAH gene transfer and methods of use thereof
|
|
CN111902164A
(zh)
|
2018-02-01 |
2020-11-06 |
同源药物公司 |
用于恢复pah基因功能的腺相关病毒组合物及其使用方法
|
|
EP3749771A1
(en)
|
2018-02-07 |
2020-12-16 |
Genethon |
Hybrid regulatory elements
|
|
CN112041437A
(zh)
|
2018-02-19 |
2020-12-04 |
同源药物公司 |
用于恢复f8基因功能的腺相关病毒组合物和其使用方法
|
|
IL276859B2
(en)
*
|
2018-02-27 |
2025-12-01 |
Univ Pennsylvania |
Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor
|
|
CN118373887A
(zh)
*
|
2018-03-16 |
2024-07-23 |
国家儿童医院研究所 |
通过衣壳修饰增加组织特异性的基因递送
|
|
US11608510B2
(en)
|
2018-03-30 |
2023-03-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Recombinant adeno-associated virus capsids with enhanced human pancreatic tropism
|
|
US20210363191A1
(en)
|
2018-04-03 |
2021-11-25 |
Stridebio, Inc. |
Antibody-evading virus vectors
|
|
CN112543766A
(zh)
|
2018-04-03 |
2021-03-23 |
斯特里迪比奥公司 |
抗体逃避性病毒载体
|
|
CA3094465A1
(en)
|
2018-04-03 |
2019-10-10 |
Stridebio, Inc. |
Virus vectors for targeting ophthalmic tissues
|
|
EP3775173A1
(en)
|
2018-04-05 |
2021-02-17 |
Genethon |
Hybrid recombinant adeno-associated virus serotype between aav9 and aavrh74 with reduced liver tropism
|
|
US12054724B2
(en)
|
2018-04-10 |
2024-08-06 |
President And Fellows Of Harvard College |
AAV vectors encoding clarin-1 or GJB2 and uses thereof
|
|
WO2019210267A2
(en)
*
|
2018-04-27 |
2019-10-31 |
Spark Therapeutics, Inc. |
Engineered aav capsids with increased tropism and aav vectors comprising the engineered capsids and methods of making and using same
|
|
WO2019212922A1
(en)
|
2018-04-29 |
2019-11-07 |
Regenxbio Inc. |
Systems and methods of spectrophotometry for the determination of genome content, capsid content and full/empty ratios of adeno-associated virus particles
|
|
WO2019212921A1
(en)
|
2018-04-29 |
2019-11-07 |
Regenxbio Inc. |
Scalable clarification process for recombinant aav production
|
|
WO2019216932A1
(en)
*
|
2018-05-07 |
2019-11-14 |
The University Of North Carolina At Chapel Hill |
Rational polyploid adeno-associated virus vectors and methods of making and using the same
|
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
|
SG11202011296VA
(en)
|
2018-05-15 |
2020-12-30 |
Voyager Therapeutics Inc |
Compositions and methods for the treatment of parkinson's disease
|
|
WO2019241535A2
(en)
|
2018-06-14 |
2019-12-19 |
Regenxbio Inc. |
Anion exchange chromatography for recombinant aav production
|
|
CA3107572A1
(en)
|
2018-08-08 |
2020-02-13 |
Genethon |
Mini-gde for the treatment of glycogen storage disease iii
|
|
EP3833745A1
(en)
|
2018-08-10 |
2021-06-16 |
REGENXBIO Inc. |
Scalable method for recombinant aav production
|
|
GB201813528D0
(en)
|
2018-08-20 |
2018-10-03 |
Ucl Business Plc |
Factor IX encoding nucleotides
|
|
US10842885B2
(en)
|
2018-08-20 |
2020-11-24 |
Ucl Business Ltd |
Factor IX encoding nucleotides
|
|
US12281321B2
(en)
|
2018-09-28 |
2025-04-22 |
Voyager Therapeutics, Inc. |
Frataxin expression constructs having engineered promoters and methods of use thereof
|
|
JP2022514112A
(ja)
|
2018-10-15 |
2022-02-09 |
リジェネクスバイオ インコーポレイテッド |
複製欠損型ウイルスベクター及びウイルスの感染性を測定するための方法
|
|
EP3870148A4
(en)
*
|
2018-10-25 |
2022-11-09 |
Takeda Pharmaceutical Company Limited |
AAV TRIPLE PLASMID SYSTEM
|
|
WO2020102667A2
(en)
*
|
2018-11-16 |
2020-05-22 |
Asklepios Biopharmaceutical, Inc. |
Vectors comprising a nucleic acid encoding lysosomal enzymes fused to a lysosomal targeting sequence
|
|
BR112021018776A2
(pt)
|
2019-03-21 |
2021-11-30 |
Stridebio Inc |
Vetores de vírus adenoassociado recombinante
|
|
MX2021011701A
(es)
*
|
2019-03-28 |
2021-12-10 |
Massachusetts Gen Hospital |
Vectores adenoasociados fabricados por ingenieria (aav) para expresion transgenica.
|
|
TW202102526A
(zh)
|
2019-04-04 |
2021-01-16 |
美商銳進科斯生物股份有限公司 |
重組腺相關病毒及其用途
|
|
HUE064411T2
(hu)
|
2019-04-11 |
2024-03-28 |
Regenxbio Inc |
Méretkizárásos kromatográfiás módszerek rekombináns adeno-asszociált víruskészítmények jellemzésére
|
|
BR112021020888A2
(pt)
|
2019-04-19 |
2021-12-21 |
Genethon |
Terapia gênica de doenças hipofosfatêmicas relacionadas a fator de crescimento fibroblástico 23
|
|
US20220143115A1
(en)
|
2019-04-19 |
2022-05-12 |
Regenxbio Inc. |
Adeno-Associated Virus Vector Formulations and Methods
|
|
KR20220012231A
(ko)
|
2019-04-24 |
2022-02-03 |
리젠엑스바이오 인크. |
완전-인간 번역 후 변형된 항체 치료제
|
|
PE20220014A1
(es)
*
|
2019-04-29 |
2022-01-11 |
Univ Pennsylvania |
Nuevas capsides de aav y composiciones que las contienen
|
|
EP3967706A4
(en)
*
|
2019-05-08 |
2022-12-28 |
Center For Excellence In Brain Science And Intelligence Technology, Chinese Academy Of Sciences |
AAV MUTANT FOR EFFICIENT INFECTION OF SUPPORT CELLS
|
|
CN110205297A
(zh)
*
|
2019-05-15 |
2019-09-06 |
华北理工大学 |
一种重组脂肪干细胞及其重组方法
|
|
EP3990030A1
(en)
|
2019-06-27 |
2022-05-04 |
Pfizer Inc. |
Methods of treating duchenne muscular dystrophy using aav mini-dystrophin gene therapy
|
|
EP3996696A1
(en)
|
2019-07-09 |
2022-05-18 |
Genethon |
Treatment of glycogen storage disease (gsd)
|
|
US20220251567A1
(en)
|
2019-07-10 |
2022-08-11 |
Inserm (Institut National De La Santè Et De La Recherche Médicale) |
Methods for the treatment of epilepsy
|
|
WO2021009805A1
(ja)
|
2019-07-12 |
2021-01-21 |
株式会社遺伝子治療研究所 |
ヒト肝臓への遺伝子導入のためのアデノ随伴ウイルスビリオン
|
|
JP2022544004A
(ja)
|
2019-07-26 |
2022-10-17 |
リジェネックスバイオ インコーポレイテッド |
操作された核酸調節エレメントならびにその使用方法
|
|
RU2751592C2
(ru)
*
|
2019-08-22 |
2021-07-15 |
Общество С Ограниченной Ответственностью "Анабион" |
Выделенный модифицированный белок VP1 капсида аденоассоциированного вируса 5 серотипа (AAV5), капсид и вектор на его основе
|
|
US20220298514A1
(en)
*
|
2019-09-11 |
2022-09-22 |
Aav Gene Therapeutics, Inc. |
Aav-zyme and use for infusion replacement therapy
|
|
KR20220083714A
(ko)
|
2019-10-17 |
2022-06-20 |
스트라이드바이오 인코포레이티드 |
니만-피크 질환 c형의 치료를 위한 아데노-연관 바이러스 벡터
|
|
WO2021078834A1
(en)
|
2019-10-22 |
2021-04-29 |
Genethon |
Chimeric acid-alpha glucosidase polypeptides and uses thereof
|
|
WO2021078833A1
(en)
|
2019-10-22 |
2021-04-29 |
Genethon |
Chimeric polypeptides and uses thereof
|
|
CN114829391A
(zh)
*
|
2019-11-14 |
2022-07-29 |
生物马林药物股份有限公司 |
用肝特异性基因疗法载体治疗遗传性血管性水肿
|
|
US20230016983A1
(en)
|
2019-11-19 |
2023-01-19 |
lNSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) |
Antisense oligonucleotides and thier use for the treatment of cancer
|
|
MX2022006427A
(es)
|
2019-11-28 |
2022-09-07 |
Regenxbio Inc |
"construcciones para terapia génica con microdistrofina y uso de las mismas.
|
|
EP4077684A1
(en)
|
2019-12-18 |
2022-10-26 |
Genethon |
Production of recombinant viral vectors from plant hairy roots
|
|
TW202140791A
(zh)
|
2020-01-13 |
2021-11-01 |
美商霍蒙拉奇醫藥公司 |
治療苯酮尿症之方法
|
|
AR121201A1
(es)
|
2020-01-29 |
2022-04-27 |
Regenxbio Inc |
Tratamiento de mucopolisacaridosis iva
|
|
EP3892720A1
(en)
|
2020-04-06 |
2021-10-13 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Presenting cell and use thereof in cell therapy
|
|
WO2021229255A1
(en)
|
2020-05-14 |
2021-11-18 |
Genethon |
Tools and method for preventing a a¥ neutralization by antibodies
|
|
EP3913060A1
(en)
|
2020-05-22 |
2021-11-24 |
Genethon |
Vectors encoding a glucose-6-phosphatase (g6pase-a) for gene therapy
|
|
TW202208632A
(zh)
|
2020-05-27 |
2022-03-01 |
美商同源醫藥公司 |
用於恢復pah基因功能的腺相關病毒組成物及其使用方法
|
|
KR20230031329A
(ko)
*
|
2020-06-30 |
2023-03-07 |
칠드런스 내셔널 메디컬 센터 |
골격 근섬유 복구를 개선하기 위한 재조합 인간 산성 스핑고미엘리나제의 용도
|
|
KR20230050336A
(ko)
|
2020-07-10 |
2023-04-14 |
인스티튜트 내셔널 드 라 싼테 에 드 라 리셰르셰 메디칼르 (인 썸) |
뇌전증을 치료하기 위한 방법과 조성물
|
|
EP4200408A1
(en)
|
2020-08-19 |
2023-06-28 |
Sarepta Therapeutics, Inc. |
Adeno-associated virus vectors for treatment of rett syndrome
|
|
US20230313152A1
(en)
|
2020-08-24 |
2023-10-05 |
Genethon |
C-terminal truncated gde for the treatment of glycogen storage disease iii
|
|
US12129287B2
(en)
|
2020-09-14 |
2024-10-29 |
President And Fellows Of Harvard College |
Recombinant adeno associated virus encoding clarin-1 and uses thereof
|
|
WO2022060916A1
(en)
|
2020-09-15 |
2022-03-24 |
Regenxbio Inc. |
Vectorized antibodies for anti-viral therapy
|
|
EP4213890A1
(en)
|
2020-09-15 |
2023-07-26 |
RegenxBio Inc. |
Vectorized lanadelumab and administration thereof
|
|
WO2022076750A2
(en)
|
2020-10-07 |
2022-04-14 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns or muscle delivery
|
|
US20230381341A1
(en)
|
2020-10-07 |
2023-11-30 |
Regenxbio Inc. |
Adeno-associated viruses for ocular delivery of gene therapy
|
|
JP2023548746A
(ja)
|
2020-10-13 |
2023-11-21 |
クリヤ セラピューティクス インコーポレイテッド |
サイトカインをコードする核酸を送達するためのウイルスベクターコンストラクトおよびがんを処置するためのその使用
|
|
EP4229205B1
(en)
|
2020-10-15 |
2025-05-14 |
F. Hoffmann-La Roche AG |
Nucleic acid constructs for va rna transcription
|
|
WO2022079082A1
(en)
|
2020-10-15 |
2022-04-21 |
F. Hoffmann-La Roche Ag |
Nucleic acid constructs for simultaneous gene activation
|
|
WO2022094157A1
(en)
|
2020-10-28 |
2022-05-05 |
Regenxbio Inc. |
Vectorized anti-cgrp and anti-cgrpr antibodies and administration thereof
|
|
CN116528892A
(zh)
|
2020-10-28 |
2023-08-01 |
再生生物股份有限公司 |
用于眼部适应症的载体化抗TNF-α抗体
|
|
CN116457373A
(zh)
|
2020-10-29 |
2023-07-18 |
再生生物股份有限公司 |
用于眼部适应症的载体化TNF-α拮抗剂
|
|
US20230390418A1
(en)
|
2020-10-29 |
2023-12-07 |
Regenxbio Inc. |
Vectorized factor xii antibodies and administration thereof
|
|
JP2023548816A
(ja)
|
2020-11-03 |
2023-11-21 |
ファイザー・インク |
陰イオン交換クロマトグラフィーによるaavベクターの精製方法
|
|
JP2023552841A
(ja)
|
2020-12-09 |
2023-12-19 |
ジェネトン |
ライソゾーム酸性リパーゼバリアント及びその使用
|
|
US20240052322A1
(en)
|
2020-12-15 |
2024-02-15 |
Pfizer Inc. |
HILIC UPLC-MS Method For Separating and Analyzing Intact Adeno-Associated Virus Capsid Proteins
|
|
EP4263841A1
(en)
|
2020-12-16 |
2023-10-25 |
REGENXBIO Inc. |
Method of producing a recombinant adeno-associated virus particle
|
|
JP2024503234A
(ja)
|
2020-12-23 |
2024-01-25 |
ファイザー・インク |
親和性クロマトグラフィーによるaavベクターの精製方法
|
|
WO2022147087A1
(en)
|
2020-12-29 |
2022-07-07 |
Regenxbio Inc. |
Tau-specific antibody gene therapy compositions, methods and uses thereof
|
|
EP4281568A1
(en)
|
2021-01-21 |
2023-11-29 |
RegenxBio Inc. |
Improved production of recombinant polypeptides and viruses
|
|
AR125143A1
(es)
|
2021-03-19 |
2023-06-14 |
Adrenas Therapeutics Inc |
Terapias génicas para la deficiencia de la 21-hidroxilasa
|
|
WO2022208342A1
(en)
|
2021-04-01 |
2022-10-06 |
Pfizer Inc. |
Pharmaceutical compositions containing adeno-associated viral vector
|
|
JP2024515626A
(ja)
*
|
2021-04-16 |
2024-04-10 |
アスクレピオス バイオファーマシューティカル, インコーポレイテッド |
血液脳関門を横断し低減された液性応答を惹起する合理的ポリプロイドaavビリオン
|
|
KR20240004564A
(ko)
|
2021-04-26 |
2024-01-11 |
리젠엑스바이오 인크. |
디스트로핀병증의 치료를 위한 마이크로디스트로핀 유전자 치료법 투여
|
|
CN117377500A
(zh)
|
2021-04-26 |
2024-01-09 |
阿雷克森国际制药有限公司 |
具有改善的组织向性的腺相关病毒载体衣壳
|
|
WO2022235614A2
(en)
|
2021-05-04 |
2022-11-10 |
Regenxbio Inc. |
Novel aav vectors and methods and uses thereof
|
|
WO2022241030A1
(en)
|
2021-05-11 |
2022-11-17 |
Regenxbio Inc. |
Treatment of duchenne muscular dystrophy and combinations thereof
|
|
MX2023015329A
(es)
|
2021-06-22 |
2024-01-23 |
Pfizer |
Produccion de vector de virus adeno-asociado en celulas de insecto.
|
|
AU2022313258A1
(en)
|
2021-07-19 |
2024-02-08 |
New York University |
Auf1 combination therapies for treatment of muscle degenerative disease
|
|
AR126840A1
(es)
*
|
2021-08-20 |
2023-11-22 |
Llc «Anabion» |
Proteína de la cápside vp1 modificada aislada del virus adeno-asociado de serotipo 5 (aav5), cápside y vector basado en esta
|
|
AR126839A1
(es)
*
|
2021-08-20 |
2023-11-22 |
Llc «Anabion» |
Proteína de la cápside vp1 modificada aislada del virus adeno-asociado de serotipo 9 (aav9), cápside y vector basado en esta
|
|
WO2023060113A1
(en)
|
2021-10-05 |
2023-04-13 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
CN118202060A
(zh)
|
2021-10-05 |
2024-06-14 |
再生生物股份有限公司 |
用于重组aav生产的组合物和方法
|
|
WO2023060272A2
(en)
|
2021-10-07 |
2023-04-13 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns tropic delivery
|
|
WO2023060269A1
(en)
|
2021-10-07 |
2023-04-13 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for targeted delivery
|
|
MX2024004217A
(es)
*
|
2021-10-08 |
2024-06-26 |
Dyno Therapeutics Inc |
Variantes de cápside y métodos de uso de estas.
|
|
CN118660710A
(zh)
|
2021-10-20 |
2024-09-17 |
罗切斯特大学 |
用于年龄相关白质损失的竞争性治疗的分离神经胶质祖细胞
|
|
EP4423285A1
(en)
|
2021-10-28 |
2024-09-04 |
RegenxBio Inc. |
Engineered nucleic acid regulatory elements and methods and uses thereof
|
|
EP4426331A1
(en)
|
2021-11-02 |
2024-09-11 |
University of Rochester |
Tcf7l2 mediated remyelination in the brain
|
|
WO2023114816A1
(en)
|
2021-12-14 |
2023-06-22 |
Neurogene, Inc. |
Recombinant optimized galc constructs and methods for treating galc-associated disorders
|
|
EP4215245A1
(en)
|
2022-01-19 |
2023-07-26 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Enhanced chimeric antigen receptor cells in hypoxic tumor microenvironment
|
|
MX2024009003A
(es)
|
2022-01-21 |
2024-09-17 |
Astrazeneca Ireland Ltd |
Terapia genica para la enfermedad de gaucher.
|
|
GB202201242D0
(en)
|
2022-01-31 |
2022-03-16 |
Univ Edinburgh |
Recombinant optimized mecp2 cassettes and methods for treating rett syndrome and related disorders
|
|
EP4493226A1
(en)
|
2022-03-13 |
2025-01-22 |
RegenxBio Inc. |
Modified muscle-specific promoters
|
|
WO2023183623A1
(en)
|
2022-03-25 |
2023-09-28 |
Regenxbio Inc. |
Dominant-negative tumor necrosis factor alpha adeno-associated virus gene therapy
|
|
CN118974274A
(zh)
|
2022-04-13 |
2024-11-15 |
豪夫迈·罗氏有限公司 |
用于确定aav基因组的方法
|
|
WO2023201277A1
(en)
|
2022-04-14 |
2023-10-19 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns tropic delivery
|
|
WO2023201308A1
(en)
|
2022-04-14 |
2023-10-19 |
Regenxbio Inc. |
Gene therapy for treating an ocular disease
|
|
GB202206336D0
(en)
|
2022-04-29 |
2022-06-15 |
Univ Edinburgh |
Recombinant therapeutic FMR1 constructs and methods of treating fragile X syndrome and related disorders
|
|
US20250288697A1
(en)
|
2022-05-03 |
2025-09-18 |
Regenxbio Inc. |
Vectorized anti-tnf-alpha inhibitors for ocular indications
|
|
EP4518972A2
(en)
|
2022-05-03 |
2025-03-12 |
RegenxBio Inc. |
Vectorized anti-complement antibodies and complement agents and administration thereof
|
|
CN119256220A
(zh)
|
2022-05-23 |
2025-01-03 |
豪夫迈·罗氏有限公司 |
用于区分aav颗粒血清型和aav颗粒荷载状态的基于拉曼的方法
|
|
EP4532737A1
(en)
|
2022-06-03 |
2025-04-09 |
F. Hoffmann-La Roche AG |
Method for producing recombinant aav particles
|
|
WO2023239627A2
(en)
|
2022-06-08 |
2023-12-14 |
Regenxbio Inc. |
Methods for recombinant aav production
|
|
JP2025524363A
(ja)
|
2022-06-09 |
2025-07-30 |
ジェネトン |
糖原病iiiの処置のためのn末端短縮型gde
|
|
WO2024003687A1
(en)
|
2022-06-28 |
2024-01-04 |
Pfizer Inc. |
Nucleic acids encoding acid alpha-glucosidase (gaa) and vectors for gene therapy
|
|
CA3261054A1
(en)
|
2022-07-14 |
2024-01-18 |
F. Hoffmann-La Roche Ag |
PROCESS FOR THE PRODUCTION OF RECOMBINANT ADENO-ASSOCIATED VIRUS PARTICLES
|
|
EP4558149A1
(en)
|
2022-07-21 |
2025-05-28 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating chronic pain disorders
|
|
IL317385A
(en)
|
2022-08-15 |
2025-02-01 |
Hoffmann La Roche |
Preventing or reducing side effects associated with recombinant viral vectors
|
|
WO2024038365A1
(en)
|
2022-08-16 |
2024-02-22 |
Pfizer Inc. |
Methods for purification of aav vectors by anion exchange chromatography
|
|
JP2025527658A
(ja)
|
2022-08-24 |
2025-08-22 |
リジェネックスバイオ インコーポレイテッド |
組換えアデノ随伴ウイルス及びその使用
|
|
WO2024056561A1
(en)
|
2022-09-12 |
2024-03-21 |
F. Hoffmann-La Roche Ag |
Method for separating full and empty aav particles
|
|
JP2025534666A
(ja)
|
2022-10-11 |
2025-10-17 |
リジェネックスバイオ インコーポレイテッド |
操作された核酸調節エレメントならびにその使用方法
|
|
EP4646478A1
(en)
|
2023-01-06 |
2025-11-12 |
Institut National de la Santé et de la Recherche Médicale |
Intravenous administration of antisense oligonucleotides for the treatment of pain
|
|
WO2024163747A2
(en)
|
2023-02-02 |
2024-08-08 |
University Of Rochester |
Competitive replacement of glial cells
|
|
AU2024216670A1
(en)
|
2023-02-07 |
2025-07-31 |
F. Hoffmann-La Roche Ag |
Method for the detection of anti-aav particle antibodies
|
|
EP4680741A2
(en)
|
2023-03-15 |
2026-01-21 |
RegenxBio Inc. |
Exon skipping gene therapy constructs, vectors and uses thereof
|
|
CN120835797A
(zh)
|
2023-03-21 |
2025-10-24 |
豪夫迈·罗氏有限公司 |
用于产生重组aav颗粒制备物的方法
|
|
WO2024211780A1
(en)
|
2023-04-07 |
2024-10-10 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
EP4694904A2
(en)
|
2023-04-13 |
2026-02-18 |
REGENXBIO Inc. |
Targeting aav capsids, methods of manufacturing and using same
|
|
WO2024213596A1
(en)
|
2023-04-13 |
2024-10-17 |
F. Hoffmann-La Roche Ag |
Improved recombinant polyadenylation signal sequences and use thereof
|
|
WO2024233099A1
(en)
*
|
2023-05-05 |
2024-11-14 |
Regeneron Pharmaceuticals, Inc. |
Labeling and anti-drug antibody assays for aav vectors
|
|
EP4709866A2
(en)
|
2023-05-07 |
2026-03-18 |
REGENXBIO Inc. |
Compositions and methods for recombinant aav production
|
|
WO2024238859A1
(en)
|
2023-05-16 |
2024-11-21 |
Regenxbio Inc. |
Vectorized c5 inhibitor agents and administration thereof
|
|
AU2024271004A1
(en)
|
2023-05-16 |
2026-01-15 |
Regenxbio Inc. |
Vectorized anti-complement antibodies and administration thereof
|
|
WO2024238853A1
(en)
|
2023-05-16 |
2024-11-21 |
Regenxbio Inc. |
Adeno-associated viruses for ocular delivery of gene therapy
|
|
CN121420060A
(zh)
|
2023-06-29 |
2026-01-27 |
吉尼松公司 |
用于治疗糖原贮积病iii的n-端截短的糖原脱支酶
|
|
WO2025008406A1
(en)
|
2023-07-04 |
2025-01-09 |
Institut National de la Santé et de la Recherche Médicale |
Antisense oligonucleotides and their use for the treatment of cancer
|
|
WO2025082618A1
(en)
|
2023-10-20 |
2025-04-24 |
Fuse Vectors Aps |
In vitro parvovirus capsid manufacturing
|
|
WO2025090427A1
(en)
|
2023-10-23 |
2025-05-01 |
University Of Rochester |
Glial-targeted relief of hyperexcitability in neurodegenerative diseases
|
|
WO2025090962A1
(en)
|
2023-10-25 |
2025-05-01 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
WO2025108407A2
(en)
|
2023-11-23 |
2025-05-30 |
Neuexcell Therapeutics (Suzhou) Co., Ltd. |
Gene therapy compositions and methods for treating glioma
|
|
WO2025113676A1
(en)
|
2023-11-29 |
2025-06-05 |
Neuexcell Therapeutics (Suzhou) Co., Ltd. |
Compositions and methods for treating stroke in primates
|
|
WO2025168663A1
(en)
|
2024-02-09 |
2025-08-14 |
F. Hoffmann-La Roche Ag |
Method for producing recombinant adeno-associated viral particles
|
|
WO2025217214A2
(en)
|
2024-04-08 |
2025-10-16 |
Regenxbio Inc. |
Recombinant adeno-associated viruses and uses thereof
|
|
WO2025217230A1
(en)
|
2024-04-08 |
2025-10-16 |
Regenxbio Inc. |
Vectorized anti-complement antibodies and complement agents and administration thereof
|
|
WO2025237990A1
(en)
|
2024-05-14 |
2025-11-20 |
Institut National de la Santé et de la Recherche Médicale |
Antisense oligonucleotides and their use for the treatment of pulmonary fibrosis
|
|
WO2025250457A1
(en)
|
2024-05-28 |
2025-12-04 |
University Of Rochester |
Enhanced brain transduction by gene therapeutics
|
|
WO2025252480A1
(en)
|
2024-06-07 |
2025-12-11 |
F. Hoffmann-La Roche Ag |
Method for purifying plasmid dna
|
|
WO2026006341A1
(en)
|
2024-06-24 |
2026-01-02 |
Regenxbio Inc. |
Microdystrophin gene therapy administration for treatment of dystrophinopathies
|
|
WO2026017965A1
(en)
|
2024-07-19 |
2026-01-22 |
The University Court Of The University Of Edinburgh |
Recombinant therapeutic fxn constructs and methods of treating friedreich ataxia and related conditions
|
|
US20260022401A1
(en)
|
2024-07-22 |
2026-01-22 |
Hoffmann-La Roche Inc. |
Novel AAV rep ORFs and Rep polypeptides
|
|
WO2026037757A1
(en)
|
2024-08-13 |
2026-02-19 |
F. Hoffmann-La Roche Ag |
Modified aav particles
|