US4039388A
(en)
|
1976-06-04 |
1977-08-02 |
The United States Of America As Represented By The Government |
Diagnostic test for Niemann-Pick disease
|
US4501729A
(en)
|
1982-12-13 |
1985-02-26 |
Research Corporation |
Aerosolized amiloride treatment of retained pulmonary secretions
|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
EP0322417A1
(en)
|
1986-09-08 |
1989-07-05 |
Applied Biotechnology, Inc. |
Empty viral capsid vaccines
|
US4968603A
(en)
|
1986-12-31 |
1990-11-06 |
The Regents Of The University Of California |
Determination of status in neoplastic disease
|
JPH04501719A
(ja)
|
1988-11-10 |
1992-03-26 |
インペリアル・キヤンサー・リサーチ・テクノロジー・リミテツド |
ポリペプチド
|
US5916563A
(en)
|
1988-11-14 |
1999-06-29 |
United States Of America |
Parvovirus protein presenting capsids
|
US5328470A
(en)
|
1989-03-31 |
1994-07-12 |
The Regents Of The University Of Michigan |
Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
|
US5399346A
(en)
|
1989-06-14 |
1995-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Gene therapy
|
ES2026826A6
(es)
|
1991-03-26 |
1992-05-01 |
Ercros Sa |
Procedimiento para la produccion de una vacuna subunidad contra el parvovirus canino y otros virus relacionados.
|
US5773278A
(en)
|
1991-05-03 |
1998-06-30 |
Mount Sinai Medical Center |
Acid sphingomyelinase gene
|
US5858784A
(en)
|
1991-12-17 |
1999-01-12 |
The Regents Of The University Of California |
Expression of cloned genes in the lung by aerosol- and liposome-based delivery
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
DK0733103T3
(da)
|
1993-11-09 |
2004-07-12 |
Univ Johns Hopkins |
Fremstilling af höje titre af rekombinante AAV vektorer
|
US5869248A
(en)
|
1994-03-07 |
1999-02-09 |
Yale University |
Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences
|
EP0755454B1
(en)
|
1994-04-13 |
2008-02-13 |
The Rockefeller University |
Aav-mediated delivery of dna to cells of the nervous system
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
US5599706A
(en)
|
1994-09-23 |
1997-02-04 |
Stinchcomb; Dan T. |
Ribozymes targeted to apo(a) mRNA
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
ATE452981T1
(de)
|
1995-06-07 |
2010-01-15 |
Univ North Carolina |
Die transduktion von myoblasten mittels vektoren aus adenoassoziierten viren
|
US6040183A
(en)
|
1995-06-07 |
2000-03-21 |
University Of North Carloina At Chapel Hill |
Helper virus-free AAV production
|
US6083702A
(en)
|
1995-12-15 |
2000-07-04 |
Intronn Holdings Llc |
Methods and compositions for use in spliceosome mediated RNA trans-splicing
|
US6013487A
(en)
|
1995-12-15 |
2000-01-11 |
Mitchell; Lloyd G. |
Chimeric RNA molecules generated by trans-splicing
|
US5962313A
(en)
|
1996-01-18 |
1999-10-05 |
Avigen, Inc. |
Adeno-associated virus vectors comprising a gene encoding a lyosomal enzyme
|
CA2265460A1
(en)
|
1996-09-11 |
1998-03-19 |
The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services |
Aav4 vector and uses thereof
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
US6426198B1
(en)
|
1997-07-03 |
2002-07-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Genes for Niemann-Pick type C disease
|
US6984517B1
(en)
|
1998-05-28 |
2006-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector and uses thereof
|
CA2329060C
(en)
|
1998-05-28 |
2011-09-13 |
John A. Chiorini |
Aav5 vector and uses thereof
|
US6562958B1
(en)
|
1998-06-09 |
2003-05-13 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to Acinetobacter baumannii for diagnostics and therapeutics
|
US8299321B2
(en)
|
1998-06-16 |
2012-10-30 |
Monsanto Technology Llc |
Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
|
US20100293663A2
(en)
|
1998-06-16 |
2010-11-18 |
Thomas La Rosa |
Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
|
US6544785B1
(en)
|
1998-09-14 |
2003-04-08 |
Mount Sinai School Of Medicine Of New York University |
Helper-free rescue of recombinant negative strand RNA viruses
|
EP1115880A2
(en)
|
1998-09-22 |
2001-07-18 |
University of Florida |
Methods for large-scale production of recombinant aav vectors
|
GB9822763D0
(en)
|
1998-10-20 |
1998-12-16 |
Univ Sheffield |
Immunoglobin variant
|
EP1127150B1
(en)
|
1998-11-05 |
2007-05-16 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
US6759237B1
(en)
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
US6491907B1
(en)
|
1998-11-10 |
2002-12-10 |
The University Of North Carolina At Chapel Hill |
Recombinant parvovirus vectors and method of making
|
US6822071B1
(en)
|
1998-11-12 |
2004-11-23 |
The Regents Of The University Of California |
Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease
|
EP1887081A2
(en)
|
1999-02-25 |
2008-02-13 |
Ceres Incorporated |
DNA Sequences
|
EP1033405A3
(en)
|
1999-02-25 |
2001-08-01 |
Ceres Incorporated |
Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
|
US20110093981A9
(en)
|
1999-05-06 |
2011-04-21 |
La Rosa Thomas J |
Nucleic acid molecules and other molecules associated with transcription in plants and uses thereof for plant improvement
|
US20080229439A1
(en)
|
1999-05-06 |
2008-09-18 |
La Rosa Thomas J |
Nucleic acid molecules and other molecules associated with transcription in plants and uses thereof for plant improvement
|
US20040031072A1
(en)
|
1999-05-06 |
2004-02-12 |
La Rosa Thomas J. |
Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
|
US20130326723A1
(en)
|
1999-05-06 |
2013-12-05 |
Thomas J. La Rosa |
Soy nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
|
US20090087878A9
(en)
|
1999-05-06 |
2009-04-02 |
La Rosa Thomas J |
Nucleic acid molecules associated with plants
|
US20110214206A1
(en)
|
1999-05-06 |
2011-09-01 |
La Rosa Thomas J |
Nucleic acid molecules and other molecules associated with plants
|
US6498244B1
(en)
|
1999-05-28 |
2002-12-24 |
Cell Genesys, Inc. |
Adeno-associated virus capsid immunologic determinants
|
US7314912B1
(en)
|
1999-06-21 |
2008-01-01 |
Medigene Aktiengesellschaft |
AAv scleroprotein, production and use thereof
|
DE19933288A1
(de)
|
1999-07-15 |
2001-01-18 |
Medigene Ag |
Strukturprotein von Adeno-assoziiertem Virus mit veränderter Antigenität, seine Herstellung und Verwendung
|
DK1916258T3
(da)
|
1999-08-09 |
2014-07-28 |
Genzyme Corp |
Forøgelse af ekspression af en enkeltstrenget, heterolog nukleotidsekvens fra rekombinante, virale vektorer ved en sådan udformning af sekvensen at den danner intrastrengbasepar
|
AU2138601A
(en)
|
1999-12-22 |
2001-07-03 |
Aventis Pasteur Limited |
Chlamydia antigens and corresponding DNA fragments and uses thereof
|
US6468524B1
(en)
|
2000-03-22 |
2002-10-22 |
The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
AAV4 vector and uses thereof
|
US20110131679A2
(en)
|
2000-04-19 |
2011-06-02 |
Thomas La Rosa |
Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
|
US20140130203A1
(en)
|
2000-04-19 |
2014-05-08 |
Thomas J. La Rosa |
Rice nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
|
WO2001081581A2
(en)
|
2000-04-21 |
2001-11-01 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of acne vulgaris
|
US7465583B2
(en)
|
2000-06-01 |
2008-12-16 |
The University Of North Carolina At Chapel Hill |
Duplexed parvovirus vectors
|
US7201898B2
(en)
|
2000-06-01 |
2007-04-10 |
The University Of North Carolina At Chapel Hill |
Methods and compounds for controlled release of recombinant parvovirus vectors
|
US7214786B2
(en)
|
2000-12-14 |
2007-05-08 |
Kovalic David K |
Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
WO2002053703A2
(en)
|
2001-01-05 |
2002-07-11 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
CA2445969A1
(en)
|
2001-04-30 |
2002-11-07 |
Cell Genesys, Inc. |
Viral-mediated delivery and in vivo expression of polynucleotides encoding anti-angiogenic proteins
|
AU2002341541A1
(en)
|
2001-06-22 |
2003-03-03 |
Syngenta Participations Ag |
Abiotic stress responsive polynucleotides and polypeptides
|
US7777097B2
(en)
|
2001-06-22 |
2010-08-17 |
Syngenta Participations Ag |
Plant disease resistance genes
|
US6623729B2
(en)
|
2001-07-09 |
2003-09-23 |
Korea Advanced Institute Of Science And Technology |
Process for preparing sustained release micelle employing conjugate of anticancer drug and biodegradable polymer
|
AU2001289843A1
(en)
|
2001-08-28 |
2002-02-13 |
Bayer Cropscience Ag |
Polypeptides for identifying herbicidally active compounds
|
WO2003033515A1
(en)
|
2001-10-15 |
2003-04-24 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of acne vulgaris
|
WO2003042361A2
(en)
|
2001-11-09 |
2003-05-22 |
Government Of The United States Of America, Department Of Health And Human Services |
Production of adeno-associated virus in insect cells
|
CA2406745C
(en)
|
2001-11-13 |
2006-01-10 |
The Trustees Of The University Of Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
|
FI3517134T3
(fi)
|
2001-12-17 |
2024-04-03 |
Univ Pennsylvania |
Adeno-assosioituneen viruksen (aav) serotyypin 8 sekvenssejä, niitä sisältäviä vektoreita ja niiden käyttöjä
|
EP3339430A1
(en)
|
2001-12-17 |
2018-06-27 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses thereof
|
WO2003093295A2
(en)
|
2002-04-30 |
2003-11-13 |
University Of North Carolina At Chapel Hill |
Secretion signal vectors
|
NZ561656A
(en)
|
2002-05-01 |
2009-03-31 |
Univ Florida |
Improved rAAV expression systems for genetic modification of specific capsid proteins
|
ITRM20020253A1
(it)
|
2002-05-08 |
2003-11-10 |
Univ Roma |
Molecole chimeriche di snrna con sequenze antisenso per le giunzioni di splicing del gene della distrofina e applicazioni terapeutiche.
|
JP2005185101A
(ja)
|
2002-05-30 |
2005-07-14 |
National Institute Of Agrobiological Sciences |
植物の全長cDNAおよびその利用
|
US20070015238A1
(en)
|
2002-06-05 |
2007-01-18 |
Snyder Richard O |
Production of pseudotyped recombinant AAV virions
|
WO2004058990A2
(en)
|
2002-12-20 |
2004-07-15 |
Applera Corporation |
Genetic polymorphisms associated with stenosis, methods of detection and uses thereof
|
PL215171B1
(pl)
|
2002-12-24 |
2013-10-31 |
Rinat Neuroscience Corp |
Przeciwcialo przeciw czynnikowi wzrostu nerwów (NGF) lub jego fragment, kompozycja farmaceutyczna, zestaw, sposób wytwarzania przeciwciala lub jego fragmentu, zastosowanie skutecznej ilosci antagonistycznego przeciwciala anty-NGF lub jego fragmentu, zastosowanie antagonistycznego przeciwciala anty-NGF lub jego fragmentu, izolowany polinukleotyd zawierajacy sekwencje nukleotydowa kodujaca przeciwcialo lub jego fragment, wektor oraz komórka gospodarza zawierajaca polinukleotyd
|
AU2004248136B2
(en)
|
2003-06-02 |
2011-09-15 |
University Of Massachusetts |
Methods and compositions for controlling efficacy of RNA silencing
|
EP2657248B1
(en)
|
2003-06-19 |
2017-03-22 |
Genzyme Corporation |
AAV virions with decreased immunoreactivity and uses therefor
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
US7473531B1
(en)
|
2003-08-08 |
2009-01-06 |
Colora Corporation |
Pancreatic cancer targets and uses thereof
|
US20060107345A1
(en)
|
2003-09-30 |
2006-05-18 |
Nickolai Alexandrov |
Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
|
EP3211085B1
(en)
|
2003-09-30 |
2021-03-31 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
CA2562024C
(en)
|
2004-04-07 |
2014-05-27 |
Rinat Neuroscience Corp. |
Methods for treating bone cancer pain by administering a nerve growth factor antagonist
|
US20060171926A1
(en)
|
2004-04-30 |
2006-08-03 |
Passini Marco A |
Gene therapy for neurometabolic disorders
|
FR2874384B1
(fr)
|
2004-08-17 |
2010-07-30 |
Genethon |
Vecteur viral adeno-associe pour realiser du saut d'exons dans un gene codant une proteine a domaines dispensables
|
JP4346526B2
(ja)
|
2004-08-31 |
2009-10-21 |
株式会社東芝 |
半導体集積回路装置
|
AU2005282352B2
(en)
|
2004-09-09 |
2011-12-01 |
The General Hospital Corporation |
Modulating phosphatase activity in cardiac cells
|
EP1828390B1
(en)
|
2004-12-15 |
2012-06-13 |
The University Of North Carolina At Chapel Hill |
Chimeric vectors
|
JP4798663B2
(ja)
|
2005-01-05 |
2011-10-19 |
塩野義製薬株式会社 |
新規血管新生抑制因子
|
US20140199313A1
(en)
|
2005-03-02 |
2014-07-17 |
Metanomics Gmbh |
Process for the Production of Fine Chemicals
|
EP2194140A2
(en)
|
2005-03-02 |
2010-06-09 |
Metanomics GmbH |
Process for the production of fine chemicals
|
US20100196335A1
(en)
|
2005-04-29 |
2010-08-05 |
Samulski Richard J |
Methods and Compositions for Regulated Expressions of Nucleic Acid at Post-Transcriptional Level
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
WO2006138005A2
(en)
|
2005-05-10 |
2006-12-28 |
Monsanto Technology, Llc |
Genes and uses for plant improvement
|
US20100095387A1
(en)
|
2005-07-15 |
2010-04-15 |
Martin Smith |
Methods and reagents for screening new drugs and for treating ion pump associated disorders and diseases
|
EP1981548A4
(en)
|
2006-01-20 |
2010-03-24 |
Univ North Carolina |
ENHANCED PRODUCTION OF INFECTIOUS VECTORS OF PARVOVIRUS IN INSECT CELLS
|
WO2007089632A2
(en)
|
2006-01-27 |
2007-08-09 |
The University Of North Carolina At Chapel Hill |
Heparin and heparan sulfate binding chimeric vectors
|
HUE041928T2
(hu)
|
2006-02-08 |
2019-06-28 |
Genzyme Corp |
Génterápia A-típusú Niemann-Pick-betegségre
|
EP1994043A4
(en)
|
2006-02-10 |
2009-05-20 |
Univ Cincinnati |
PROTEIN-A PHOSPHATASE INHIBITOR AS REGULATOR OF CARDIAC FUNCTION
|
EP2007795B1
(en)
|
2006-03-30 |
2016-11-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Aav capsid proteins
|
ES2400235T3
(es)
|
2006-04-28 |
2013-04-08 |
The Trustees Of The University Of Pennsylvania |
Método de producción escalable de AAV
|
JP2009535339A
(ja)
|
2006-04-28 |
2009-10-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
低下されたキャプシド免疫原性を有する改変aavベクターおよびその使用
|
KR101589259B1
(ko)
|
2006-06-21 |
2016-02-01 |
유니큐어 아이피 비.브이. |
곤충세포 내 aav의 생산에 유용한 aav-rep78의 번역을 위한 변형된 개시 코돈을 갖는 벡터
|
EP2125006B1
(en)
|
2007-01-18 |
2013-10-16 |
University of Missouri-Columbia |
Synthetic mini/micro-dystrophin genes to restore nnos to the sarcolemma
|
US20120322861A1
(en)
|
2007-02-23 |
2012-12-20 |
Barry John Byrne |
Compositions and Methods for Treating Diseases
|
US9725485B2
(en)
|
2012-05-15 |
2017-08-08 |
University Of Florida Research Foundation, Inc. |
AAV vectors with high transduction efficiency and uses thereof for gene therapy
|
US9611302B2
(en)
|
2007-04-09 |
2017-04-04 |
University Of Florida Research Foundation, Inc. |
High-transduction-efficiency RAAV vectors, compositions, and methods of use
|
EP2623605B1
(en)
|
2007-04-09 |
2018-11-28 |
University of Florida Research Foundation, Inc. |
RAAV vector compositions having tyrosine-modified capsid proteins and methods for use
|
KR100911624B1
(ko)
|
2007-05-14 |
2009-08-12 |
연세대학교 산학협력단 |
Il-12 및 il-23의 효율적인 공동발현 방법
|
US8664475B2
(en)
|
2007-09-18 |
2014-03-04 |
Basf Plant Science Gmbh |
Plants with increased yield
|
EP2058401A1
(en)
|
2007-10-05 |
2009-05-13 |
Genethon |
Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
|
US10526627B2
(en)
|
2007-11-30 |
2020-01-07 |
Corn Products Development, Inc |
Method for producing high molecular weight reduced viscosity starch pastes
|
US20090221620A1
(en)
|
2008-02-20 |
2009-09-03 |
Celera Corporation |
Gentic polymorphisms associated with stroke, methods of detection and uses thereof
|
CN102007214A
(zh)
|
2008-02-20 |
2011-04-06 |
塞瑞斯公司 |
赋予植物提高的氮利用效率特性的核苷酸序列和相应的多肽
|
WO2009108274A2
(en)
|
2008-02-26 |
2009-09-03 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
CA2762118A1
(en)
|
2008-05-20 |
2010-01-28 |
Eos Neuroscience, Inc. |
Vectors for delivery of light-sensitive proteins and methods of use
|
JP2010002479A
(ja)
|
2008-06-18 |
2010-01-07 |
Crossfor:Kk |
メガネレンズ用装飾体およびメガネ用装飾体装着具
|
US9415121B2
(en)
|
2008-12-19 |
2016-08-16 |
Nationwide Children's Hospital |
Delivery of MECP2 polynucleotide using recombinant AAV9
|
US8889641B2
(en)
*
|
2009-02-11 |
2014-11-18 |
The University Of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
US8679837B2
(en)
|
2009-04-02 |
2014-03-25 |
University Of Florida Research Foundation, Inc. |
Inducible system for highly efficient production of recombinant Adeno-associated virus (rAAV) vectors
|
HUE039345T2
(hu)
|
2009-05-02 |
2018-12-28 |
Genzyme Corp |
Génterápia neurodegeneratív rendellenességekre
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
US20120252877A1
(en)
|
2009-08-14 |
2012-10-04 |
Theramind Research, Llc |
Methods and compositions for treatment of tuberous sclerosis complex
|
EP2292781A1
(en)
|
2009-08-17 |
2011-03-09 |
Genethon |
Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions
|
WO2011122950A1
(en)
|
2010-04-01 |
2011-10-06 |
Amsterdam Molecular Therapeutics (Amt) Ip B.V. |
Monomeric duplex aav vectors
|
EP2826860B1
(en)
|
2010-04-23 |
2018-08-22 |
University of Massachusetts |
CNS targeting AAV vectors and methods of use thereof
|
US8628966B2
(en)
|
2010-04-30 |
2014-01-14 |
City Of Hope |
CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer
|
US8927514B2
(en)
|
2010-04-30 |
2015-01-06 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
US9839696B2
(en)
|
2010-04-30 |
2017-12-12 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
JP5704361B2
(ja)
|
2010-10-27 |
2015-04-22 |
学校法人自治医科大学 |
神経系細胞への遺伝子導入のためのアデノ随伴ウイルスビリオン
|
ES2684307T3
(es)
|
2010-11-05 |
2018-10-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Proteínas estabilizadas de tipo opsina de función escalonada y métodos de uso de las mismas
|
WO2012064960A2
(en)
|
2010-11-10 |
2012-05-18 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for generating adeno-associated viral vectors with undetectable capsid gene contamination
|
WO2012109570A1
(en)
|
2011-02-10 |
2012-08-16 |
The University Of North Carolina At Chapel Hill |
Viral vectors with modified transduction profiles and methods of making and using the same
|
US10392632B2
(en)
|
2011-02-14 |
2019-08-27 |
The Children's Hospital Of Philadelphia |
AAV8 vector with enhanced functional activity and methods of use thereof
|
WO2012159006A2
(en)
|
2011-05-18 |
2012-11-22 |
University Of Florida Research Foundation, Inc. |
Polypeptides and vectors for targeting her2/neu expressing cells and uses thereof
|
WO2013016315A1
(en)
|
2011-07-28 |
2013-01-31 |
Trustees Of Dartmouth College |
Methods for treating niemann-pick type c disease
|
CA3177742A1
(en)
|
2011-08-23 |
2013-02-28 |
Evogene Ltd. |
Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics
|
WO2013078400A1
(en)
|
2011-11-22 |
2013-05-30 |
The Children's Hospital Of Philadelphia |
Virus vectors for highly efficient transgene delivery
|
FI124176B
(en)
|
2011-12-01 |
2014-04-15 |
Helsingin Yliopisto |
Polypeptide, polynucleotide, expression cassette, vector, host cell, plant and uses
|
US20140350087A9
(en)
|
2012-03-22 |
2014-11-27 |
Halozyme, Inc. |
Oncovector Nucleic Acid Molecules and Methods of Use
|
CN104321432B
(zh)
|
2012-03-27 |
2018-08-10 |
库瑞瓦格股份公司 |
包含5′top utr的人工核酸分子
|
BR122021020419B1
(pt)
|
2012-04-18 |
2023-01-17 |
The Children's Hospital Of Philadelphia |
Vetor de vírus adeno-associado (aav) que compreende uma proteína de capsídeo vp1, composições farmacêuticas compreendendo o mesmo, e seus usos
|
US20140162319A2
(en)
|
2012-05-02 |
2014-06-12 |
Sangeetha Hareendran |
Nucleotide sequences, methods, kit and a recombinant cell thereof
|
EP3470523A1
(en)
|
2012-05-09 |
2019-04-17 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
US10294281B2
(en)
|
2012-05-15 |
2019-05-21 |
University Of Florida Research Foundation, Incorporated |
High-transduction-efficiency rAAV vectors, compositions, and methods of use
|
EP2492347A1
(en)
|
2012-05-22 |
2012-08-29 |
Laboratorios Del. Dr. Esteve, S.A. |
Methods for the production of vectors
|
CA2877428A1
(en)
|
2012-06-21 |
2013-12-27 |
Association Institut De Myologie |
Widespread gene delivery of gene therapy vectors
|
CN104619832B
(zh)
|
2012-07-06 |
2021-03-16 |
衣阿华大学研究基金会 |
经修饰的腺伴随病毒载体组合物
|
DK3444342T3
(da)
|
2012-07-11 |
2020-08-24 |
Sangamo Therapeutics Inc |
Fremgangsmåder og sammensætninger til behandlingen af lysosomale aflejringssygdomme
|
US9683268B2
(en)
|
2012-09-19 |
2017-06-20 |
Beth Israel Deaconess |
Viruses associated with immunodeficiency and enteropathy and methods using same
|
WO2014045674A1
(ja)
|
2012-09-19 |
2014-03-27 |
国立大学法人東京大学 |
神経活動依存的プロモータ活性を有するdna、及びこれを含むベクター
|
CN111621507A
(zh)
|
2012-09-28 |
2020-09-04 |
北卡罗来纳-查佩尔山大学 |
靶向少突胶质细胞的aav载体
|
US9066966B2
(en)
|
2013-02-01 |
2015-06-30 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods and pharmaceutical compositions for the treatment of cardiomyopathy due to friedreich ataxia
|
DK2954051T3
(da)
|
2013-02-08 |
2019-07-08 |
Univ Pennsylvania |
Modificeret kapsid til genoverførsel til behandling af nethinden
|
US10266845B2
(en)
|
2013-02-08 |
2019-04-23 |
The Trustees Of The University Of Pennsylvania |
Enhanced AAV-mediated gene transfer for retinal therapies
|
WO2014153083A1
(en)
|
2013-03-14 |
2014-09-25 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for predicting age of onset of a lysosomal storage disease or a disease associated with a lysosomal defect
|
DK2968605T3
(da)
|
2013-03-15 |
2022-09-26 |
Univ North Carolina Chapel Hill |
Fremgangsmåder og sammensætninger til dobbelte glycanbindende aav-vektorer
|
SG10201709552XA
(en)
|
2013-05-21 |
2018-01-30 |
Univ Florida |
Capsid-modified, raav3 vector compositions and uses in gene therapy of human liver cancer
|
JP6600624B2
(ja)
|
2013-05-31 |
2019-10-30 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
アデノ随伴ウイルス変異体及びその使用方法
|
US9840719B2
(en)
|
2013-07-22 |
2017-12-12 |
The Children's Hospital Of Philadelphia |
Variant AAV and compositions, methods and uses for gene transfer to cells, organs and tissues
|
DE102013215817A1
(de)
|
2013-08-09 |
2015-02-12 |
Universitätsklinikum Hamburg-Eppendorf |
Neue peptide mit spezifität für die lunge
|
EP3561062A1
(en)
*
|
2013-09-13 |
2019-10-30 |
California Institute of Technology |
Selective recovery
|
US9710484B2
(en)
*
|
2013-09-17 |
2017-07-18 |
Here Global B.V. |
Method and apparatus for associating physical locations to online entities
|
WO2015048534A1
(en)
|
2013-09-26 |
2015-04-02 |
University Of Florida Research Foundation, Inc. |
Synthetic combinatorial aav capsid library for targeted gene therapy
|
US20160256571A1
(en)
|
2013-09-30 |
2016-09-08 |
Sanofi |
Invention
|
EP3744730A1
(en)
|
2013-10-11 |
2020-12-02 |
Massachusetts Eye & Ear Infirmary |
Methods of predicting ancestral virus sequences and uses thereof
|
CN104592364B
(zh)
*
|
2013-10-30 |
2018-05-01 |
北京大学 |
定点突变和定点修饰的腺相关病毒、其制备方法及应用
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
WO2015127128A2
(en)
|
2014-02-19 |
2015-08-27 |
University Of Massachusetts |
Recombinant aavs having useful transcytosis properties
|
WO2015126972A1
(en)
|
2014-02-21 |
2015-08-27 |
University Of Florida Research Foundation, Inc. |
Methods and compositions for gene delivery to on bipolar cells
|
WO2015134643A1
(en)
|
2014-03-04 |
2015-09-11 |
University Of Florida Research Foundation, Inc. |
Improved raav vectors and methods for transduction of photoreceptors and rpe cells
|
WO2015164757A1
(en)
|
2014-04-25 |
2015-10-29 |
Oregon Health & Science University |
Methods of viral neutralizing antibody epitope mapping
|
SI3137497T1
(sl)
|
2014-05-02 |
2021-08-31 |
Genzyme Corporation |
Vektorji AAV za gensko terapijo mrežnice in centralnega živčnega sistema
|
AU2015265412B2
(en)
|
2014-05-28 |
2021-03-25 |
Evogene Ltd. |
Isolated polynucleotides, polypeptides and methods of using same for increasing abiotic stress tolerance, biomass and yield of plants
|
EP3151866B1
(en)
|
2014-06-09 |
2023-03-08 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
CA2953341C
(en)
|
2014-06-25 |
2023-01-24 |
Acuitas Therapeutics Inc. |
Lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
US9818383B2
(en)
|
2014-07-28 |
2017-11-14 |
University Of Connecticut |
Methods and systems for non-destructive analysis of objects and production of replica objects
|
CN113667696A
(zh)
|
2014-09-24 |
2021-11-19 |
希望之城 |
用于高效基因组编辑的腺相关病毒载体变异体和其方法
|
JP6842410B2
(ja)
|
2014-10-03 |
2021-03-17 |
ユニバーシティ オブ マサチューセッツ |
新規の高効率ライブラリーにより同定されるaavベクター
|
CN107073051B
(zh)
|
2014-10-21 |
2021-08-24 |
马萨诸塞大学 |
重组aav变体及其用途
|
AU2016206624B2
(en)
|
2015-01-14 |
2020-08-06 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeted gene transfer
|
EP3245221A4
(en)
|
2015-01-16 |
2018-06-13 |
Voyager Therapeutics, Inc. |
Central nervous system targeting polynucleotides
|
WO2016126857A1
(en)
|
2015-02-03 |
2016-08-11 |
University Of Florida Research Foundation, Inc. |
Recombinant aav1, aav5, and aav6 capsid mutants and uses thereof
|
GB201502306D0
(en)
|
2015-02-12 |
2015-04-01 |
Hansa Medical Ab |
Protein
|
GB201502305D0
(en)
|
2015-02-12 |
2015-04-01 |
Hansa Medical Ab |
Protein
|
WO2016134338A1
(en)
|
2015-02-19 |
2016-08-25 |
University Of Florida Research Foundation, Inc. |
Recombinant aav vectors for gene therapy of human hematopoietic disorders
|
EP3265178A4
(en)
|
2015-03-02 |
2018-09-05 |
Adverum Biotechnologies, Inc. |
Compositions and methods for intravitreal delivery of polynucleotides to retinal cones
|
EP3273999A1
(en)
|
2015-03-23 |
2018-01-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment and the prevention of neurological phenotype associated with friedreich ataxia
|
MX2017012097A
(es)
|
2015-03-24 |
2018-06-15 |
Univ California |
Variantes de virus adenoasociado y métodos de uso de estas.
|
US10081659B2
(en)
|
2015-04-06 |
2018-09-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Adeno-associated vectors for enhanced transduction and reduced immunogenicity
|
ES2755725T3
(es)
|
2015-04-08 |
2020-04-23 |
Us Health |
Terapia génica viral como tratamiento para una enfermedad o un trastorno por almacenamiento de colesterol
|
US11020443B2
(en)
|
2015-04-23 |
2021-06-01 |
University Of Massachusetts |
Modulation of AAV vector transgene expression
|
US11046955B2
(en)
|
2015-04-24 |
2021-06-29 |
University Of Massachusetts |
Modified AAV constructs and uses thereof
|
US11104917B2
(en)
|
2015-05-08 |
2021-08-31 |
Children's Medical Research Institute |
Promoters for expression of heterologous genes
|
GB201508026D0
(en)
*
|
2015-05-11 |
2015-06-24 |
Ucl Business Plc |
Capsid
|
GB201508025D0
(en)
|
2015-05-11 |
2015-06-24 |
Ucl Business Plc |
Fabry disease gene therapy
|
JP6805174B2
(ja)
|
2015-05-12 |
2020-12-23 |
アメリカ合衆国 |
神経成長因子シグナルペプチド及び副甲状腺ホルモンを含むaav分離株及び融合タンパク質
|
WO2017015102A1
(en)
|
2015-07-17 |
2017-01-26 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for achieving high levels of transduction in human liver cells
|
WO2017013648A1
(en)
|
2015-07-19 |
2017-01-26 |
Yeda Research And Development Co. Ltd. |
SELECTIVE INHIBITORS OF Alpha2-CONTAINING ISOFORMS OF Na,K-ATPase AND USE THEREOF FOR REDUCTION OF INTRAOCULAR PRESSURE
|
WO2017019876A1
(en)
|
2015-07-28 |
2017-02-02 |
University Of Massachusetts |
Transgenic expression of dnase i in vivo delivered by an adeno-associated virus vector
|
LT3872085T
(lt)
|
2015-07-30 |
2023-05-10 |
Massachusetts Eye & Ear Infirmary |
Viruso prototipo sekos ir jų panaudojimas
|
JP7064214B2
(ja)
|
2015-09-28 |
2022-05-10 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
抗体回避性ウイルスベクターのための方法および組成物
|
WO2017066764A2
(en)
|
2015-10-16 |
2017-04-20 |
William Marsh Rice University |
Modification of n-terminal region of capsid proteins for enhanced properties of adeno-associated viruses
|
CA3002980A1
(en)
|
2015-10-22 |
2017-04-27 |
University Of Massachusetts |
Prostate-targeting adeno-associated virus serotype vectors
|
WO2017077451A1
(en)
|
2015-11-05 |
2017-05-11 |
Bamboo Therapeutics, Inc. |
Modified friedreich ataxia genes and vectors for gene therapy
|
CA3006309A1
(en)
|
2015-12-01 |
2017-06-08 |
Spark Therapeutics, Inc. |
Scalable methods for producing recombinant adeno-associated viral (aav) vector in serum-free suspension cell culture system suitable for clinical use
|
US10406244B2
(en)
|
2015-12-02 |
2019-09-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
AAV vectors with expanded packaging capacity
|
US10385320B2
(en)
|
2015-12-02 |
2019-08-20 |
The Board Of Trustees Of The Leland Stanford Junior University |
Recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism
|
SG11201804713VA
(en)
|
2015-12-11 |
2018-07-30 |
California Inst Of Techn |
TARGETING PEPTIDES FOR DIRECTING ADENO-ASSOCIATED VIRUSES (AAVs)
|
MX2018007237A
(es)
|
2015-12-14 |
2018-12-11 |
Univ North Carolina Chapel Hill |
Proteinas de cápside modificadas para un suministro mejorado de vectores de parvovirus.
|
EP4094780A3
(en)
|
2016-02-12 |
2023-02-08 |
University of Massachusetts |
Anti-angiogenic mirna therapeutics for inhibiting corneal neovascularization
|
CN109415704B
(zh)
|
2016-02-16 |
2022-02-25 |
利兰斯坦福初级大学董事会 |
对先已存在的人中和抗体有抗性的新型重组腺相关病毒衣壳
|
AU2017223465A1
(en)
|
2016-02-22 |
2018-08-09 |
The University Of North Carolina At Chapel Hill |
AAV-IDUA vector for treatment of MPS I-associated blindness
|
JP7140683B2
(ja)
|
2016-04-15 |
2022-09-21 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
新規なaav8変異カプシド及びそれを含有する組成物
|
US11866462B2
(en)
|
2016-05-04 |
2024-01-09 |
Oregon Health & Science University |
Recombinant adeno-associated viral vectors
|
NZ748395A
(en)
|
2016-05-13 |
2019-12-20 |
4D Molecular Therapeutics Inc |
Adeno-associated virus variant capsids and methods of use thereof
|
KR20240056729A
(ko)
|
2016-05-18 |
2024-04-30 |
보이저 테라퓨틱스, 인크. |
조절성 폴리뉴클레오티드
|
CN109790549A
(zh)
|
2016-07-21 |
2019-05-21 |
星火治疗有限公司 |
生产高产重组腺相关病毒(rAAV)载体可扩展高回收法及其产生的重组腺相关病毒(rAAV)载体
|
JP6994018B2
(ja)
|
2016-07-26 |
2022-01-14 |
バイオマリン ファーマシューティカル インコーポレイテッド |
新規アデノ随伴ウイルスキャプシドタンパク質
|
CA3033125A1
(en)
|
2016-08-16 |
2018-02-22 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for targeted gene transfer
|
IL265045B2
(en)
|
2016-09-08 |
2023-09-01 |
Bluebird Bio Inc |
Variants of endonuclease pd-1, compositions and methods of use
|
US11078238B2
(en)
|
2016-09-29 |
2021-08-03 |
University Of Florida Research Foundation, Incorporated |
AAVrh.10 variants with host antibody escape capabilities and altered tissue targeting properties
|
EP3528785A4
(en)
|
2016-10-19 |
2020-12-02 |
Adverum Biotechnologies, Inc. |
MODIFIED AAV CASPIDS AND USES THEREOF
|
US20230048025A1
(en)
|
2016-12-22 |
2023-02-16 |
Oregon Health & Science University |
Adeno associated viral vectors
|
AU2018221738A1
(en)
|
2017-02-15 |
2019-08-22 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for gene transfer across the vasculature
|
JP7455579B2
(ja)
|
2017-02-28 |
2024-03-26 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
新規アデノ随伴ウイルス(aav)クレードfベクター及びその用途
|
IL268891B1
(en)
|
2017-03-15 |
2024-05-01 |
Univ North Carolina Chapel Hill |
Polyploid gland associated virus vectors and methods of making and using the same.
|
US10550405B2
(en)
|
2017-03-15 |
2020-02-04 |
The University Of North Carolina At Chapel Hill |
Rational polyploid adeno-associated virus vectors and methods of making and using the same
|
WO2018204764A1
(en)
|
2017-05-05 |
2018-11-08 |
Camp4 Therapeutics Corporation |
Identification and targeted modulation of gene signaling networks
|
JP7330899B2
(ja)
|
2017-05-10 |
2023-08-22 |
マサチューセッツ アイ アンド イヤー インファーマリー |
ウイルスのアセンブリ活性化タンパク質(aap)依存性を改変する方法および組成物
|
EA201992882A1
(ru)
|
2017-06-06 |
2020-05-25 |
Юниверсити Оф Массачусеттс |
САМОРЕГУЛИРУЕМЫЕ ВЕКТОРЫ НА ОСНОВЕ AAV ДЛЯ БЕЗОПАСНОЙ ЭКСПРЕССИИ MeCP2 ПРИ СИНДРОМЕ PETTA
|
WO2018237066A1
(en)
|
2017-06-20 |
2018-12-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
CODON OPTIMIZED HUMAN NPC1 GENES FOR THE TREATMENT OF C1-TYPE NIEMANN-PICK DISEASE AND ASSOCIATED STATES
|
WO2019006418A2
(en)
|
2017-06-30 |
2019-01-03 |
Intima Bioscience, Inc. |
ADENO-ASSOCIATED VIRAL VECTORS FOR GENE THERAPY
|
US20210228738A1
(en)
|
2017-07-17 |
2021-07-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
|
WO2019025984A1
(en)
|
2017-07-31 |
2019-02-07 |
Reflection Biotechnologies Limited |
CELLULAR MODELS AND THERAPIES FOR OCULAR DISEASES
|
MX2020006764A
(es)
|
2018-01-17 |
2021-01-08 |
Meiragtx Uk Ii Ltd |
Una proteína de la cápside de raav modificada para terapia génica.
|
MX2020008932A
(es)
|
2018-02-27 |
2020-10-01 |
Univ Pennsylvania |
Novedosos vectores de virus adenoasociado (aav), vectores de aav que tienen una desamidacion reducida de la capside y usos de estos.
|
CA3091806A1
(en)
|
2018-02-27 |
2019-09-06 |
The Trustees Of The University Of Pennsylvania |
Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor
|
EP3759218A4
(en)
|
2018-02-28 |
2021-12-08 |
The University of North Carolina at Chapel Hill |
METHODS AND COMPOSITIONS FOR ANTIBODY AVOIDING VIRAL VECTORS
|
US20210010028A1
(en)
|
2018-03-06 |
2021-01-14 |
Voyager Therapeutics, Inc. |
Insect cell manufactured partial self-complementary aav genomes
|
CA3092871A1
(en)
|
2018-03-06 |
2019-09-12 |
University Of Florida Research Foundation, Incorporated |
Aav chimeras
|
WO2019178412A1
(en)
|
2018-03-16 |
2019-09-19 |
Research Institute At Nationwide Children's Hospital |
Increasing tissue specific gene delivery by capsid modification
|
EP3774854A1
(en)
|
2018-04-03 |
2021-02-17 |
Stridebio, Inc. |
Antibody-evading virus vectors
|
CN112533644A
(zh)
|
2018-04-03 |
2021-03-19 |
斯特里迪比奥公司 |
靶向眼组织的病毒载体
|
CN112543766A
(zh)
*
|
2018-04-03 |
2021-03-23 |
斯特里迪比奥公司 |
抗体逃避性病毒载体
|
CN113302201A
(zh)
|
2018-11-21 |
2021-08-24 |
斯特里迪比奥公司 |
重组病毒载体和用于产生所述重组病毒载体的核酸
|
EP4269579A3
(en)
|
2019-01-04 |
2024-01-24 |
Ultragenyx Pharmaceutical Inc. |
Gene therapy constructs for treating wilson disease
|
EA202192501A1
(ru)
|
2019-03-21 |
2021-12-16 |
Страйдбайо, Инк. |
Рекомбинантные аденоассоциированные вирусные векторы
|
JP2022531809A
(ja)
|
2019-05-14 |
2022-07-11 |
デューク ユニバーシティ |
ATPase媒介性疾患の処置のための組成物および方法
|
US20240131185A1
(en)
|
2019-10-17 |
2024-04-25 |
Stridebio, Inc. |
Aav transfer cassette
|
WO2021076925A1
(en)
|
2019-10-17 |
2021-04-22 |
Stridebio, Inc. |
Adeno-associated viral vectors for treatment of niemann-pick disease type c
|
IL300717A
(en)
|
2020-08-19 |
2023-04-01 |
Sarepta Therapeutics Inc |
ADENO-related virus vectors for the treatment of RETT syndrome
|