LT3872085T - Viruso prototipo sekos ir jų panaudojimas - Google Patents
Viruso prototipo sekos ir jų panaudojimasInfo
- Publication number
- LT3872085T LT3872085T LTEP21161372.4T LT21161372T LT3872085T LT 3872085 T LT3872085 T LT 3872085T LT 21161372 T LT21161372 T LT 21161372T LT 3872085 T LT3872085 T LT 3872085T
- Authority
- LT
- Lithuania
- Prior art keywords
- aav sequences
- ancestral aav
- ancestral
- sequences
- aav
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14151—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562199059P | 2015-07-30 | 2015-07-30 | |
| US201562203002P | 2015-08-10 | 2015-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3872085T true LT3872085T (lt) | 2023-05-10 |
Family
ID=57885044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP21161372.4T LT3872085T (lt) | 2015-07-30 | 2016-07-29 | Viruso prototipo sekos ir jų panaudojimas |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10738087B2 (lt) |
| EP (3) | EP4134375A1 (lt) |
| JP (2) | JP7166168B2 (lt) |
| CN (1) | CN108603235A (lt) |
| AU (1) | AU2016298394C1 (lt) |
| CA (2) | CA3126951A1 (lt) |
| DK (1) | DK3872085T3 (lt) |
| ES (1) | ES2945427T3 (lt) |
| FI (1) | FI3872085T3 (lt) |
| HK (1) | HK1254848A1 (lt) |
| HU (1) | HUE061388T2 (lt) |
| LT (1) | LT3872085T (lt) |
| PL (1) | PL3872085T3 (lt) |
| PT (1) | PT3872085T (lt) |
| WO (1) | WO2017019994A2 (lt) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2359867T3 (en) * | 2005-04-07 | 2015-01-05 | Univ Pennsylvania | A method for increasing an AAV vector function |
| WO2015191508A1 (en) | 2014-06-09 | 2015-12-17 | Voyager Therapeutics, Inc. | Chimeric capsids |
| BR112017009497A2 (pt) | 2014-11-05 | 2018-02-06 | Voyager Therapeutics, Inc. | polinucleotídeos de aadc para o tratamento da doença de parkinson |
| KR20230145206A (ko) | 2014-11-14 | 2023-10-17 | 보이저 테라퓨틱스, 인크. | 조절성 폴리뉴클레오티드 |
| BR112017010087A2 (pt) | 2014-11-14 | 2018-06-05 | Voyager Therapeutics, Inc. | composições e métodos para tratar esclerose lateral amiotrófica (ela) |
| EP3230441A4 (en) | 2014-12-12 | 2018-10-03 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scaav |
| CN108603235A (zh) * | 2015-07-30 | 2018-09-28 | 马萨诸塞眼科耳科诊所 | 祖先病毒序列及其用途 |
| SG10202107733QA (en) | 2015-09-28 | 2021-09-29 | Univ North Carolina Chapel Hill | Methods and compositions for antibody-evading virus vectors |
| AU2016362477A1 (en) | 2015-12-02 | 2018-06-14 | Voyager Therapeutics, Inc. | Assays for the detection of AAV neutralizing antibodies |
| EP3448987A4 (en) | 2016-04-29 | 2020-05-27 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR THE TREATMENT OF DISEASES |
| WO2017189959A1 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| MX2018014154A (es) | 2016-05-18 | 2019-05-06 | Voyager Therapeutics Inc | Polinucleotidos moduladores. |
| RU2764587C2 (ru) | 2016-05-18 | 2022-01-18 | Вояджер Терапьютикс, Инк. | Способы и композиции для лечения хореи гентингтона |
| MX2019000962A (es) | 2016-07-26 | 2019-08-01 | Biomarin Pharm Inc | Novedosas proteinas de la capside del virus adenoasociado. |
| JP2019530737A (ja) | 2016-08-23 | 2019-10-24 | アコーオス インコーポレイテッド | ヒト対象において非加齢性聴力障害を治療するための組成物および方法 |
| EP3831281A1 (en) | 2016-08-30 | 2021-06-09 | The Regents of The University of California | Methods for biomedical targeting and delivery and devices and systems for practicing the same |
| EP3619308A4 (en) | 2017-05-05 | 2021-01-27 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS OF TREATMENT FOR HUNTINGTON'S MORBUS |
| AU2018261790A1 (en) | 2017-05-05 | 2019-11-28 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (ALS) |
| JP7330899B2 (ja) | 2017-05-10 | 2023-08-22 | マサチューセッツ アイ アンド イヤー インファーマリー | ウイルスのアセンブリ活性化タンパク質（ａａｐ）依存性を改変する方法および組成物 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| WO2019018342A1 (en) | 2017-07-17 | 2019-01-24 | Voyager Therapeutics, Inc. | NETWORK EQUIPMENT TRACK GUIDE SYSTEM |
| WO2019028306A2 (en) | 2017-08-03 | 2019-02-07 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR ADMINISTRATION OF ADENO-ASSOCIATED VIRUSES |
| US20200231986A1 (en) * | 2017-09-29 | 2020-07-23 | Massachusetts Eye And Ear Infirmary | Production of adeno-associated viruses in insect cells |
| WO2019079242A1 (en) | 2017-10-16 | 2019-04-25 | Voyager Therapeutics, Inc. | TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
| EP4124658A3 (en) | 2017-10-16 | 2023-04-19 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
| WO2019195449A1 (en) | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Antibody-evading virus vectors |
| AU2019265560A1 (en) | 2018-05-09 | 2020-11-26 | Biomarin Pharmaceutical Inc. | Methods of treating phenylketonuria |
| KR20210010491A (ko) | 2018-05-11 | 2021-01-27 | 매사추세츠 아이 앤드 이어 인퍼머리 | 아데노-연관 바이러스의 간-특이적 향성 |
| TW202005978A (zh) | 2018-05-14 | 2020-02-01 | 美商拜奧馬林製藥公司 | 新穎肝靶向腺相關病毒載體 |
| UY38407A (es) | 2018-10-15 | 2020-05-29 | Novartis Ag | Anticuerpos estabilizadores de trem2 |
| MX2021011468A (es) | 2019-03-21 | 2021-12-15 | Vectores de virus adenoasociados recombinantes. | |
| JP2022530633A (ja) * | 2019-04-29 | 2022-06-30 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 新規ａａｖカプシドおよびそれを含む組成物 |
| CN110423778B (zh) * | 2019-07-26 | 2023-04-21 | 上海科技大学 | 一种逆行性重组2型腺相关病毒在感染螺旋神经元中的应用 |
| WO2021073567A1 (en) * | 2019-10-16 | 2021-04-22 | Wuxi Apptec (Shanghai) Co., Ltd. | Novel aav library |
| WO2021073568A1 (en) * | 2019-10-16 | 2021-04-22 | Wuxi Apptec (Shanghai) Co., Ltd. | A novel aav variant |
| WO2021076925A1 (en) | 2019-10-17 | 2021-04-22 | Stridebio, Inc. | Adeno-associated viral vectors for treatment of niemann-pick disease type c |
| BR112022016596A2 (pt) | 2020-02-21 | 2022-11-16 | Akouos Inc | Composições e métodos para o tratamento de debilitação auditiva não associada à idade em um indivíduo humano |
| EP4244209A1 (en) | 2020-11-11 | 2023-09-20 | European Molecular Biology Laboratory | Modified viral particles for gene therapy |
| JP2024517957A (ja) | 2021-05-12 | 2024-04-23 | フォンダツィオーネ テレトン | ベクター系 |
| WO2023214346A1 (en) | 2022-05-06 | 2023-11-09 | Novartis Ag | Novel recombinant aav vp2 fusion polypeptides |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US242997A (en) * | 1881-06-14 | Reversible seat | ||
| US368925A (en) * | 1887-08-30 | Feed mechanism for sewing-machines | ||
| US5037384B2 (en) | 1988-01-12 | 1995-12-26 | Cornell Res Foundation Inc | Method and apparatus for the treatment of complicated retinal detachments |
| US20040115621A1 (en) | 2000-02-18 | 2004-06-17 | Allen Rodrigo | Ancestral viruses and vaccines |
| US6692526B1 (en) | 2000-03-15 | 2004-02-17 | Michael E. Snyder | Ophthalmological surgery colorant and delivery system |
| DK3211085T3 (da) * | 2003-09-30 | 2021-06-21 | Univ Pennsylvania | Klader af adeno-associeret virus (aav), sekvenser, vektorer indeholdende disse og anvendelser deraf |
| DK2359867T3 (en) | 2005-04-07 | 2015-01-05 | Univ Pennsylvania | A method for increasing an AAV vector function |
| US8388668B2 (en) | 2005-08-05 | 2013-03-05 | Gholam A. Peyman | Methods to regulate polarization of excitable cells |
| JP2016514152A (ja) * | 2013-03-13 | 2016-05-19 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア | アデノ随伴ウイルスベクターおよびその使用の方法 |
| CN115141260A (zh) * | 2013-10-11 | 2022-10-04 | 马萨诸塞眼科耳科诊所 | 预测祖先病毒序列的方法及其用途 |
| CN108603235A (zh) * | 2015-07-30 | 2018-09-28 | 马萨诸塞眼科耳科诊所 | 祖先病毒序列及其用途 |
| JP7330899B2 (ja) * | 2017-05-10 | 2023-08-22 | マサチューセッツ アイ アンド イヤー インファーマリー | ウイルスのアセンブリ活性化タンパク質（ａａｐ）依存性を改変する方法および組成物 |
-
2016
- 2016-07-29 CN CN201680057177.2A patent/CN108603235A/zh active Pending
- 2016-07-29 DK DK21161372.4T patent/DK3872085T3/da active
- 2016-07-29 EP EP22182170.5A patent/EP4134375A1/en not_active Withdrawn
- 2016-07-29 HU HUE21161372A patent/HUE061388T2/hu unknown
- 2016-07-29 EP EP16831443.3A patent/EP3329017B1/en not_active Withdrawn - After Issue
- 2016-07-29 CA CA3126951A patent/CA3126951A1/en not_active Abandoned
- 2016-07-29 PT PT211613724T patent/PT3872085T/pt unknown
- 2016-07-29 FI FIEP21161372.4T patent/FI3872085T3/fi active
- 2016-07-29 CA CA2994160A patent/CA2994160C/en active Active
- 2016-07-29 PL PL21161372.4T patent/PL3872085T3/pl unknown
- 2016-07-29 LT LTEP21161372.4T patent/LT3872085T/lt unknown
- 2016-07-29 US US15/748,738 patent/US10738087B2/en active Active
- 2016-07-29 AU AU2016298394A patent/AU2016298394C1/en active Active
- 2016-07-29 WO PCT/US2016/044819 patent/WO2017019994A2/en unknown
- 2016-07-29 JP JP2018504699A patent/JP7166168B2/ja active Active
- 2016-07-29 EP EP21161372.4A patent/EP3872085B1/en active Active
- 2016-07-29 ES ES21161372T patent/ES2945427T3/es active Active
-
2018
- 2018-10-31 HK HK18113943.1A patent/HK1254848A1/zh unknown
-
2020
- 2020-08-10 US US16/989,454 patent/US20210017235A1/en active Pending
-
2021
- 2021-06-16 JP JP2021099934A patent/JP7222028B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2945427T3 (es) | 2023-07-03 |
| CA3126951A1 (en) | 2017-02-02 |
| EP3872085B1 (en) | 2023-03-01 |
| HUE061388T2 (hu) | 2023-06-28 |
| CN108603235A (zh) | 2018-09-28 |
| EP3329017A2 (en) | 2018-06-06 |
| DK3872085T3 (da) | 2023-04-03 |
| FI3872085T3 (fi) | 2023-04-19 |
| JP7166168B2 (ja) | 2022-11-07 |
| EP3329017A4 (en) | 2018-12-26 |
| HK1254848A1 (zh) | 2019-07-26 |
| JP2018521670A (ja) | 2018-08-09 |
| PL3872085T3 (pl) | 2023-06-05 |
| US20190100560A1 (en) | 2019-04-04 |
| EP4134375A1 (en) | 2023-02-15 |
| AU2016298394A1 (en) | 2018-02-22 |
| AU2016298394C1 (en) | 2024-02-15 |
| CA2994160C (en) | 2021-08-10 |
| EP3872085A1 (en) | 2021-09-01 |
| AU2016298394B2 (en) | 2022-07-28 |
| EP3329017B1 (en) | 2021-03-10 |
| PT3872085T (pt) | 2023-04-13 |
| US10738087B2 (en) | 2020-08-11 |
| US20210017235A1 (en) | 2021-01-21 |
| JP7222028B2 (ja) | 2023-02-14 |
| WO2017019994A2 (en) | 2017-02-02 |
| CA2994160A1 (en) | 2017-02-02 |
| JP2021175397A (ja) | 2021-11-04 |
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