|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US3896111A
(en)
|
1973-02-20 |
1975-07-22 |
Research Corp |
Ansa macrolides
|
|
US4151042A
(en)
|
1977-03-31 |
1979-04-24 |
Takeda Chemical Industries, Ltd. |
Method for producing maytansinol and its derivatives
|
|
US4137230A
(en)
|
1977-11-14 |
1979-01-30 |
Takeda Chemical Industries, Ltd. |
Method for the production of maytansinoids
|
|
USRE30985E
(en)
|
1978-01-01 |
1982-06-29 |
|
Serum-free cell culture media
|
|
US4265814A
(en)
|
1978-03-24 |
1981-05-05 |
Takeda Chemical Industries |
Matansinol 3-n-hexadecanoate
|
|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
|
JPS5562090A
(en)
|
1978-10-27 |
1980-05-10 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS5566585A
(en)
|
1978-11-14 |
1980-05-20 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS55164687A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
|
JPS55164685A
(en)
|
1979-06-08 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS55164686A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
US4309428A
(en)
|
1979-07-30 |
1982-01-05 |
Takeda Chemical Industries, Ltd. |
Maytansinoids
|
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
|
US4419446A
(en)
|
1980-12-31 |
1983-12-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant DNA process utilizing a papilloma virus DNA as a vector
|
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
|
US4596792A
(en)
|
1981-09-04 |
1986-06-24 |
The Regents Of The University Of California |
Safe vaccine for hepatitis containing polymerized serum albumin
|
|
US4741900A
(en)
|
1982-11-16 |
1988-05-03 |
Cytogen Corporation |
Antibody-metal ion complexes
|
|
US4601978A
(en)
|
1982-11-24 |
1986-07-22 |
The Regents Of The University Of California |
Mammalian metallothionein promoter system
|
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
|
US4599231A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
|
US4599230A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
|
US4965199A
(en)
|
1984-04-20 |
1990-10-23 |
Genentech, Inc. |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
|
|
US4970198A
(en)
|
1985-10-17 |
1990-11-13 |
American Cyanamid Company |
Antitumor antibiotics (LL-E33288 complex)
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
US4601903A
(en)
|
1985-05-01 |
1986-07-22 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease
|
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
US5075109A
(en)
|
1986-10-24 |
1991-12-24 |
Southern Research Institute |
Method of potentiating an immune response
|
|
US6024983A
(en)
|
1986-10-24 |
2000-02-15 |
Southern Research Institute |
Composition for delivering bioactive agents for immune response and its preparation
|
|
US4886499A
(en)
|
1986-12-18 |
1989-12-12 |
Hoffmann-La Roche Inc. |
Portable injection appliance
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
US5079233A
(en)
|
1987-01-30 |
1992-01-07 |
American Cyanamid Company |
N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same
|
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
|
JP3101690B2
(ja)
|
1987-03-18 |
2000-10-23 |
エス・ビィ・２・インコーポレイテッド |
変性抗体の、または変性抗体に関する改良
|
|
US4849222A
(en)
|
1987-03-24 |
1989-07-18 |
The Procter & Gamble Company |
Mixtures for treating hypercholesterolemia
|
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
|
US4975278A
(en)
|
1988-02-26 |
1990-12-04 |
Bristol-Myers Company |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
|
|
US5004697A
(en)
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
|
US5053394A
(en)
|
1988-09-21 |
1991-10-01 |
American Cyanamid Company |
Targeted forms of methyltrithio antitumor agents
|
|
JP2670680B2
(ja)
|
1988-02-24 |
1997-10-29 |
株式会社ビーエムジー |
生理活性物質含有ポリ乳酸系微小球およびその製造法
|
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
|
JPH01287029A
(ja)
|
1988-05-13 |
1989-11-17 |
Mect Corp |
新規抗ウィルス剤
|
|
WO1990003430A1
(en)
|
1988-09-23 |
1990-04-05 |
Cetus Corporation |
Cell culture medium for enhanced cell growth, culture longevity and product expression
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
DK0479909T3
(da)
|
1989-06-29 |
1997-04-07 |
Medarex Inc |
Bispecifikke reagenser til AIDS-behandling
|
|
US5690938A
(en)
|
1989-07-07 |
1997-11-25 |
Oravax, Inc. |
Oral immunization with multiple particulate antigen delivery system
|
|
US5518725A
(en)
|
1989-09-25 |
1996-05-21 |
University Of Utah Research Foundation |
Vaccine compositions and method for induction of mucosal immune response via systemic vaccination
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5238843A
(en)
|
1989-10-27 |
1993-08-24 |
Genencor International, Inc. |
Method for cleaning a surface on which is bound a glycoside-containing substance
|
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
|
SG48759A1
(en)
|
1990-01-12 |
2002-07-23 |
Abgenix Inc |
Generation of xenogenic antibodies
|
|
US5061620A
(en)
|
1990-03-30 |
1991-10-29 |
Systemix, Inc. |
Human hematopoietic stem cell
|
|
US5112596A
(en)
|
1990-04-23 |
1992-05-12 |
Alkermes, Inc. |
Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
|
|
US5268164A
(en)
|
1990-04-23 |
1993-12-07 |
Alkermes, Inc. |
Increasing blood-brain barrier permeability with permeabilizer peptides
|
|
DK0528859T3
(da)
|
1990-04-24 |
1998-09-14 |
Flustat Pty Ltd |
Oral vaccine, som omfatter antigen knyttet til overfladen af røde blodlegemer
|
|
SK282950B6
(sk)
|
1990-04-24 |
2003-01-09 |
Biota Scientific Management Pty Ltd |
Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
JPH06500011A
(ja)
|
1990-06-29 |
1994-01-06 |
ラージ スケール バイオロジー コーポレイション |
形質転換された微生物によるメラニンの製造
|
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
ES2246502T3
(es)
|
1990-08-29 |
2006-02-16 |
Genpharm International, Inc. |
Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5714374A
(en)
|
1990-09-12 |
1998-02-03 |
Rutgers University |
Chimeric rhinoviruses
|
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
|
WO1992006691A1
(en)
|
1990-10-19 |
1992-04-30 |
Biota Scientific Management Pty. Ltd. |
Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
|
|
US5264365A
(en)
|
1990-11-09 |
1993-11-23 |
Board Of Regents, The University Of Texas System |
Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides
|
|
US5508192A
(en)
|
1990-11-09 |
1996-04-16 |
Board Of Regents, The University Of Texas System |
Bacterial host strains for producing proteolytically sensitive polypeptides
|
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
ATE158415T1
(de)
|
1991-04-30 |
1997-10-15 |
Eukarion Inc |
Kationisierte antikörper gegen intrazelluläre eiweisse
|
|
JP4124480B2
(ja)
|
1991-06-14 |
2008-07-23 |
ジェネンテック・インコーポレーテッド |
免疫グロブリン変異体
|
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
|
EP0604580A1
(en)
|
1991-09-19 |
1994-07-06 |
Genentech, Inc. |
EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab') 2? ANTIBODIES
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
CA2119930C
(en)
|
1991-09-23 |
2002-10-01 |
Hendricus R. J. M. Hoogenboom |
Production of chimeric antibodies - a combinatorial approach
|
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
US5288502A
(en)
|
1991-10-16 |
1994-02-22 |
The University Of Texas System |
Preparation and uses of multi-phase microspheres
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
DE69229880T2
(de)
|
1991-11-19 |
2000-05-04 |
The University Of Virginia Patent Foundation, Charlottesville |
Kombinierte virustatikum-antimediator-behandlung (covam) von gewöhnlichen erkältungen
|
|
JPH0826057B2
(ja)
|
1992-01-16 |
1996-03-13 |
株式会社ディ・ディ・エス研究所 |
シアル酸オリゴ糖誘導体及び微粒子キャリヤー
|
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
AU675929B2
(en)
|
1992-02-06 |
1997-02-27 |
Curis, Inc. |
Biosynthetic binding protein for cancer marker
|
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5326856A
(en)
|
1992-04-09 |
1994-07-05 |
Cytogen Corporation |
Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
JP2904647B2
(ja)
|
1992-06-12 |
1999-06-14 |
株式会社蛋白工学研究所 |
５−ブロム−４−クロロインド−３−イル−２−シアル酸の製造方法
|
|
WO1994002610A1
(en)
|
1992-07-17 |
1994-02-03 |
Dana-Farber Cancer Institute |
Method of intracellular binding of target molecules
|
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
JPH07509250A
(ja)
|
1992-07-27 |
1995-10-12 |
アメリカ合衆国 |
血液脳バリヤーへのリポソームの標的化
|
|
ATE149570T1
(de)
|
1992-08-17 |
1997-03-15 |
Genentech Inc |
Bispezifische immunoadhesine
|
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
|
WO1994009020A1
(fr)
|
1992-10-22 |
1994-04-28 |
Kirin Beer Kabushiki Kaisha |
Nouveau shingoglycolipide et son utilisation
|
|
US5807722A
(en)
|
1992-10-30 |
1998-09-15 |
Bioengineering Resources, Inc. |
Biological production of acetic acid from waste gases with Clostridium ljungdahlii
|
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
|
EP0669836B1
(en)
|
1992-11-13 |
1996-07-03 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human b lymphocyte restricted differentiation antigen for treatment of b cell lymphoma
|
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
|
US5374541A
(en)
|
1993-05-04 |
1994-12-20 |
The Scripps Research Institute |
Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides
|
|
US20020037517A1
(en)
|
1993-05-28 |
2002-03-28 |
Hutchens T. William |
Methods for sequencing biopolymers
|
|
AU691811B2
(en)
|
1993-06-16 |
1998-05-28 |
Celltech Therapeutics Limited |
Antibodies
|
|
ATE224184T1
(de)
|
1993-10-22 |
2002-10-15 |
Genentech Inc |
Verfahren zur mikroverkapselung von antigenen und verwendung der zusammensetzungen als impfstoffe
|
|
US5369017A
(en)
|
1994-02-04 |
1994-11-29 |
The Scripps Research Institute |
Process for solid phase glycopeptide synthesis
|
|
EP0746564B1
(en)
|
1994-02-25 |
1998-12-02 |
E.I. Du Pont De Nemours And Company |
4-n-substituted sialic acids and their sialosides
|
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
US5622701A
(en)
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
|
EP0771208B1
(en)
|
1994-08-12 |
2005-10-19 |
Immunomedics, Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US5639635A
(en)
|
1994-11-03 |
1997-06-17 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
|
WO1996016673A1
(en)
|
1994-12-02 |
1996-06-06 |
Chiron Corporation |
Method of promoting an immune response with a bispecific antibody
|
|
US5663149A
(en)
|
1994-12-13 |
1997-09-02 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
|
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US6673533B1
(en)
|
1995-03-10 |
2004-01-06 |
Meso Scale Technologies, Llc. |
Multi-array multi-specific electrochemiluminescence testing
|
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
WO1996036436A1
(en)
|
1995-04-25 |
1996-11-21 |
Irori |
Remotely programmable matrices with memories and uses thereof
|
|
KR20050085971A
(ko)
|
1995-04-27 |
2005-08-29 |
아브게닉스, 인크. |
면역화된 제노마우스 유래의 인간 항체
|
|
EP0823941A4
(en)
|
1995-04-28 |
2001-09-19 |
Abgenix Inc |
HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
|
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
|
US5837234A
(en)
|
1995-06-07 |
1998-11-17 |
Cytotherapeutics, Inc. |
Bioartificial organ containing cells encapsulated in a permselective polyether suflfone membrane
|
|
AU6505796A
(en)
|
1995-07-26 |
1997-02-26 |
Maxim Pharmaceuticals |
Mucosal delivery of polynucleotides
|
|
DE19544393A1
(de)
|
1995-11-15 |
1997-05-22 |
Hoechst Schering Agrevo Gmbh |
Synergistische herbizide Mischungen
|
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
|
US6027888A
(en)
|
1996-04-05 |
2000-02-22 |
Board Of Regents, The University Of Texas System |
Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells
|
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
US6340702B1
(en)
|
1996-07-22 |
2002-01-22 |
Sankyo Company, Limited |
Neuraminic acid derivatives, their preparation and their medical use
|
|
US6506564B1
(en)
|
1996-07-29 |
2003-01-14 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
|
AU732916C
(en)
|
1996-11-14 |
2002-06-06 |
Biota Scientific Management Pty Ltd |
Method and novel compounds for use therein
|
|
WO1998024893A2
(en)
|
1996-12-03 |
1998-06-11 |
Abgenix, Inc. |
TRANSGENIC MAMMALS HAVING HUMAN IG LOCI INCLUDING PLURAL VH AND Vλ REGIONS AND ANTIBODIES PRODUCED THEREFROM
|
|
TW555562B
(en)
|
1996-12-27 |
2003-10-01 |
Kirin Brewery |
Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
|
|
DE69835201T2
(de)
|
1997-04-18 |
2007-06-14 |
Novartis Ag |
Neoglycoproteine
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
US6083715A
(en)
|
1997-06-09 |
2000-07-04 |
Board Of Regents, The University Of Texas System |
Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
|
|
JPH1135593A
(ja)
|
1997-07-18 |
1999-02-09 |
Daikin Ind Ltd |
２−フルオロフコシル−ｎ−アロイルグルコサミン誘導体及びその中間物、並びにそれらの製造方法
|
|
TW480247B
(en)
|
1997-12-12 |
2002-03-21 |
Gilead Sciences Inc |
Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
|
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
|
WO1999049019A2
(en)
|
1998-03-27 |
1999-09-30 |
Prolume, Ltd. |
Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics
|
|
DE69937291T2
(de)
|
1998-04-02 |
2008-07-10 |
Genentech, Inc., South San Francisco |
Antikörpervarianten und fragmente davon
|
|
PT2180007E
(pt)
|
1998-04-20 |
2013-11-25 |
Roche Glycart Ag |
Engenharia de glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
|
|
US6455571B1
(en)
|
1998-04-23 |
2002-09-24 |
Abbott Laboratories |
Inhibitors of neuraminidases
|
|
AU760048B2
(en)
|
1998-05-06 |
2003-05-08 |
Genentech Inc. |
Protein purification by ion exchange chromatography
|
|
JP3773153B2
(ja)
|
1998-05-29 |
2006-05-10 |
独立行政法人理化学研究所 |
シアル酸誘導体
|
|
US6528286B1
(en)
|
1998-05-29 |
2003-03-04 |
Genentech, Inc. |
Mammalian cell culture process for producing glycoproteins
|
|
ATE234468T1
(de)
|
1998-09-18 |
2003-03-15 |
Massachusetts Inst Technology |
Biologische verwendungen von halbleitenden nanokristallen
|
|
FR2783523B1
(fr)
|
1998-09-21 |
2006-01-20 |
Goemar Lab Sa |
Fuco-oligosaccharides, enzyme pour leur preparation a partir des fucanes, bacterie productrice de l'enzyme et applications des fuco-oligosaccharides a la protection des plantes
|
|
US6696304B1
(en)
|
1999-02-24 |
2004-02-24 |
Luminex Corporation |
Particulate solid phase immobilized protein quantitation
|
|
AUPP913999A0
(en)
|
1999-03-12 |
1999-04-01 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
US7090973B1
(en)
|
1999-04-09 |
2006-08-15 |
Oscient Pharmaceuticals Corporation |
Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics
|
|
US7854934B2
(en)
*
|
1999-08-20 |
2010-12-21 |
Sloan-Kettering Institute For Cancer Research |
Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
AUPQ422399A0
(en)
|
1999-11-24 |
1999-12-16 |
University Of New South Wales, The |
Method of screening transformed or transfected cells
|
|
US6727356B1
(en)
|
1999-12-08 |
2004-04-27 |
Epoch Pharmaceuticals, Inc. |
Fluorescent quenching detection reagents and methods
|
|
US20020098513A1
(en)
|
2000-02-17 |
2002-07-25 |
Glycominds Ltd. |
Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
|
|
US7019129B1
(en)
|
2000-05-09 |
2006-03-28 |
Biosearch Technologies, Inc. |
Dark quenchers for donor-acceptor energy transfer
|
|
US7863020B2
(en)
|
2000-06-28 |
2011-01-04 |
Glycofi, Inc. |
Production of sialylated N-glycans in lower eukaryotes
|
|
US6514221B2
(en)
|
2000-07-27 |
2003-02-04 |
Brigham And Women's Hospital, Inc. |
Blood-brain barrier opening
|
|
AU2001286930A1
(en)
|
2000-08-30 |
2002-03-13 |
The Board Of Trustees Of The Leland Stanford Junior University |
Glucocorticoid blocking agents for increasing blood-brain barrier permeability
|
|
AUPR001000A0
(en)
|
2000-09-08 |
2000-10-05 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
US7034036B2
(en)
|
2000-10-30 |
2006-04-25 |
Pain Therapeutics, Inc. |
Inhibitors of ABC drug transporters at the blood-brain barrier
|
|
US20030083299A1
(en)
|
2000-11-04 |
2003-05-01 |
Ferguson Ian A. |
Non-invasive delivery of polypeptides through the blood-brain barrier
|
|
JP2002153272A
(ja)
|
2000-11-24 |
2002-05-28 |
Inst Of Physical & Chemical Res |
生体分子マイクロアレイ
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
AU2002338446A1
(en)
|
2001-01-23 |
2002-11-05 |
University Of Rochester Medical Center |
Methods of producing or identifying intrabodies in eukaryotic cells
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
DE10121982B4
(de)
|
2001-05-05 |
2008-01-24 |
Lts Lohmann Therapie-Systeme Ag |
Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung
|
|
JP2002371087A
(ja)
|
2001-06-15 |
2002-12-26 |
Mitsubishi Chemicals Corp |
有機ホスホン酸
|
|
DE60234057D1
(de)
|
2001-07-25 |
2009-11-26 |
Raptor Pharmaceutical Inc |
Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
|
|
AU2002327338A1
(en)
|
2001-07-25 |
2003-02-17 |
New York University |
Use of glycosylceramides as adjuvants for vaccines against infections and cancer
|
|
NZ603111A
(en)
|
2001-08-03 |
2014-05-30 |
Roche Glycart Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
|
BRPI0213207B1
(pt)
|
2001-10-10 |
2021-06-15 |
Novo Nordisk A/S |
Processo in vitro, isento de células, para a remodelagem de um peptídeo e processos para formar um conjugado entre peptídeos e um grupo de modificação
|
|
JP4763237B2
(ja)
|
2001-10-19 |
2011-08-31 |
キャボット コーポレイション |
基板上に導電性電子部品を製造する方法
|
|
AUPR879601A0
(en)
|
2001-11-09 |
2001-12-06 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
US20030229451A1
(en)
|
2001-11-21 |
2003-12-11 |
Carol Hamilton |
Methods and systems for analyzing complex biological systems
|
|
CN101914158A
(zh)
|
2002-02-14 |
2010-12-15 |
免疫医疗公司 |
抗cd 20抗体及其融合蛋白和使用方法
|
|
US20030162695A1
(en)
|
2002-02-27 |
2003-08-28 |
Schatzberg Alan F. |
Glucocorticoid blocking agents for increasing blood-brain barrier permeability
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
AU2003219277A1
(en)
|
2002-03-14 |
2003-09-29 |
Medical Research Council |
Intracellular antibodies
|
|
DE60328481D1
(de)
|
2002-05-14 |
2009-09-03 |
Novartis Vaccines & Diagnostic |
Schleimhautapplizierter impfstoff, der das adjuvanz chitosan und menigokokkenantigene enthält
|
|
CN1665831A
(zh)
|
2002-07-08 |
2005-09-07 |
普利瓦研究院有限公司 |
作为甾类/非甾类抗炎、抗肿瘤和抗病毒活性分子载体的新化合物、组合物
|
|
US20080070324A1
(en)
|
2002-07-15 |
2008-03-20 |
Floyd Alton D |
Quantity control device for microscope slide staining assays
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
US20040062682A1
(en)
|
2002-09-30 |
2004-04-01 |
Rakow Neal Anthony |
Colorimetric sensor
|
|
NZ581541A
(en)
|
2002-10-17 |
2011-07-29 |
Genmab As |
Human monoclonal antibodies against CD20
|
|
CN100386068C
(zh)
|
2002-12-03 |
2008-05-07 |
布朗歇特洛克菲勒神经科学研究所 |
传输物质穿过血脑屏障的人工低密度脂蛋白载体
|
|
RS20100366A
(sr)
|
2002-12-16 |
2011-04-30 |
Genentech, Inc. |
Varijante imunoglobulina i njihova upotreba
|
|
WO2004063351A2
(en)
|
2003-01-09 |
2004-07-29 |
Macrogenics, Inc. |
IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
AR044388A1
(es)
|
2003-05-20 |
2005-09-07 |
Applied Molecular Evolution |
Moleculas de union a cd20
|
|
US20040259142A1
(en)
|
2003-06-04 |
2004-12-23 |
Imperial College Innovations Limited |
Products and methods
|
|
KR20060031809A
(ko)
|
2003-06-09 |
2006-04-13 |
더 리젠츠 오브 더 유니버시티 오브 미시간 |
암 치료 및 진단용 조성물 및 방법
|
|
JP4148844B2
(ja)
|
2003-06-11 |
2008-09-10 |
ソニー・エリクソン・モバイルコミュニケーションズ株式会社 |
情報端末装置及び音声付画像ファイルの出力方法
|
|
EP1663239A4
(en)
|
2003-09-10 |
2008-07-23 |
Cedars Sinai Medical Center |
KALIUM CHANNEL-MEDIATED FEEDING OF MEDICINES BY THE BLOOD BRAIN BARRIER
|
|
EP1673113B1
(en)
|
2003-09-15 |
2010-12-29 |
Smart Tech LP |
Implants with attached silylated therapeutic agents
|
|
JP2007522094A
(ja)
|
2003-09-22 |
2007-08-09 |
アシドフィル エルエルシー |
小分子組成物、及びその組成物を使用して薬物効率を高めるための方法
|
|
US7019288B2
(en)
|
2003-09-30 |
2006-03-28 |
Sequenom, Inc. |
Methods of making substrates for mass spectrometry analysis and related devices
|
|
US20050221337A1
(en)
|
2003-10-02 |
2005-10-06 |
Massachusetts Institute Of Technology |
Microarrays and microspheres comprising oligosaccharides, complex carbohydrates or glycoproteins
|
|
ME01775B
(me)
|
2003-11-05 |
2011-02-28 |
Glycart Biotechnology Ag |
Cd20 antitijela sa povećanim afinitetom vezivanja za fc receptor i efektornom funkcijom
|
|
CN103394083B
(zh)
|
2003-11-06 |
2017-07-18 |
西雅图基因公司 |
能够与配体偶联的单甲基缬氨酸化合物
|
|
US20050255491A1
(en)
|
2003-11-13 |
2005-11-17 |
Lee Frank D |
Small molecule and peptide arrays and uses thereof
|
|
WO2005088310A2
(en)
|
2004-03-05 |
2005-09-22 |
The Scripps Research Institute |
High throughput glycan microarrays
|
|
US20050221397A1
(en)
|
2004-03-30 |
2005-10-06 |
Northern Advancement Center For Science & Technology |
RM2 antigen (beta1,4-GalNAc-disialyl-Lc4) as prostate cancer-associated antigen
|
|
WO2005103081A2
(en)
|
2004-04-20 |
2005-11-03 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
|
ITMI20040928A1
(it)
|
2004-05-07 |
2004-08-07 |
Uni Di Bologna Dipartiment O D |
Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata
|
|
WO2006002382A2
(en)
|
2004-06-24 |
2006-01-05 |
The Scripps Research Institute |
Arrays with cleavable linkers
|
|
SI1771482T1
(sl)
|
2004-07-22 |
2014-12-31 |
Genentech, Inc. |
Sestavek HER2 protitelesa
|
|
US8022043B2
(en)
|
2004-08-27 |
2011-09-20 |
Albert Einstein College Of Medicine Of Yeshiva University |
Ceramide derivatives as modulators of immunity and autoimmunity
|
|
WO2006055925A2
(en)
|
2004-11-19 |
2006-05-26 |
Swiss Federal Institute Of Technology |
Microarrays for analyte detection
|
|
WO2006064983A1
(en)
|
2004-12-14 |
2006-06-22 |
Korea Research Institute Of Bioscience And Biotechnology |
Monoclonal antibody specific human embryonic stem cell
|
|
AU2005322027B2
(en)
|
2004-12-28 |
2013-09-12 |
The Rockefeller University |
Glycolipids and analogues thereof as antigens for NK Tcells
|
|
US7923013B2
(en)
|
2004-12-28 |
2011-04-12 |
The Rockefeller University |
Glycolipids and analogues thereof as antigens for NKT cells
|
|
BRPI0609543B1
(pt)
|
2005-03-31 |
2021-11-09 |
Biomedics Inc |
Anticorpo monoclonal anti-cd20, hibridoma, anticorpo monoclonal anti-cd20 quimérico, anticorpo monoclonal anti-cd20 humanizado, agente de diagnóstico, e, agente terapêutico
|
|
JP2009508467A
(ja)
|
2005-05-24 |
2009-03-05 |
アベスタゲン リミテッド |
Ｂ細胞リンパ腫の治療のためのｃｄ２０に対するモノクローナル抗体を生成する方法
|
|
KR20080031001A
(ko)
|
2005-06-02 |
2008-04-07 |
아스트라제네카 아베 |
Ｃｄ20에 대한 항체 및 그의 용도
|
|
US7781203B2
(en)
|
2005-12-29 |
2010-08-24 |
Corning Incorporated |
Supports for assaying analytes and methods of making and using thereof
|
|
CA2647632C
(en)
|
2006-03-27 |
2017-06-27 |
University Of Maryland Biotechnology Institute |
Glycoprotein synthesis and remodeling by enzymatic transglycosylation
|
|
EA014533B1
(ru)
|
2006-05-18 |
2010-12-30 |
Ветеринермедицинише Универзитет Вин |
Способы обнаружения вирусов гриппа
|
|
US20100173323A1
(en)
|
2006-06-09 |
2010-07-08 |
University Of Maryland, Baltimore |
Glycosylation engineered antibody therapy
|
|
JP5215298B2
(ja)
|
2006-07-12 |
2013-06-19 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グリコシル化された基質から切断される末端単糖の固相検出
|
|
JP2008025989A
(ja)
|
2006-07-15 |
2008-02-07 |
Keio Gijuku |
局在表面プラズモン共鳴法と質量分析法によるリガンドの分析方法及びそのためのセンサー素子
|
|
US8444971B2
(en)
|
2006-11-27 |
2013-05-21 |
Diadexus, Inc. |
OVR110 antibody compositions and methods of use
|
|
CA2591496C
(en)
|
2006-12-18 |
2014-09-02 |
Japan Science And Technology Agency |
Method of measuring interaction between biomaterial and sugar chain, method of evaluating biomaterial in sugar chain selectivity, method of screening biomaterial, method of patterning biomaterials, and kits for performing these methods
|
|
US20100047827A1
(en)
|
2007-01-18 |
2010-02-25 |
Suomen Punainen Risti, Veripalvelu |
Novel specific cell binders
|
|
US20100068806A1
(en)
|
2007-01-18 |
2010-03-18 |
Suomen Punainen Risti, Veripalvelu |
Novel methods and reagents directed to production of cells
|
|
US20080220988A1
(en)
|
2007-03-07 |
2008-09-11 |
Ada Technologies, Inc. |
Preparing carbohydrate microarrays and conjugated nanoparticles
|
|
PT2123271E
(pt)
|
2007-03-07 |
2011-12-20 |
Daiichi Sankyo Co Ltd |
Fármaco para o tratamento de gripe
|
|
DK2308514T3
(da)
|
2007-03-23 |
2013-09-02 |
To Bbb Holding B V |
Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren
|
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
|
US7943330B2
(en)
|
2007-03-23 |
2011-05-17 |
Academia Sinica |
Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins
|
|
CA2683681A1
(en)
|
2007-04-13 |
2008-10-23 |
Academia Sinica |
Alpha-galactosyl ceramide analogs and their use as immunotherapies
|
|
CA2685015A1
(en)
|
2007-04-23 |
2008-11-06 |
Schering Corporation |
Anti-mdl-1 antibodies
|
|
JP5345059B2
(ja)
|
2007-08-24 |
2013-11-20 |
Ｌｓｉｐファンド運営合同会社 |
婦人科癌の検出方法
|
|
WO2009029888A2
(en)
|
2007-08-31 |
2009-03-05 |
Chi-Huey Wong |
Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity
|
|
FR2921387B1
(fr)
|
2007-09-26 |
2012-04-20 |
Sanofi Pasteur |
Procede de production du virus de la grippe
|
|
US8647626B2
(en)
|
2007-10-02 |
2014-02-11 |
Avaxia Biologics, Incorporated |
Compositions comprising TNF-specific antibodies for oral delivery
|
|
US20090123439A1
(en)
|
2007-11-09 |
2009-05-14 |
The Jackson Laboratory |
Diagnostic and prognosis methods for cancer stem cells
|
|
WO2009083246A1
(en)
|
2007-12-31 |
2009-07-09 |
Bayer Schering Pharma Aktiengesellschaft |
Antibodies to tnf alpha
|
|
RU2536256C2
(ru)
|
2008-03-21 |
2014-12-20 |
ДАНИСКО ЮЭс ИНК. |
Композиция ферментной смеси для гидролиза смеси целлюлозных и гемицеллюлозных материалов (варианты) и способы ее использования (варианты)
|
|
JP5561700B2
(ja)
|
2008-03-25 |
2014-07-30 |
独立行政法人理化学研究所 |
新規糖脂質及びその用途
|
|
US8383554B2
(en)
|
2008-04-14 |
2013-02-26 |
Academia Sinica |
Quantitative microarray of intact glycolipid CD1d interaction and correlation with cell-based cytokine production
|
|
US8906832B2
(en)
|
2008-04-30 |
2014-12-09 |
Academia Sinica |
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants
|
|
CN102036658A
(zh)
|
2008-05-23 |
2011-04-27 |
香港大学 |
治疗流感的联合疗法
|
|
WO2009154964A2
(en)
|
2008-05-30 |
2009-12-23 |
Glycome Technologies Inc. |
Methods for structural analysis of glycans
|
|
AU2009268937A1
(en)
|
2008-06-16 |
2010-01-14 |
Aj Park |
Compositions for inducing immune responses specific to Globo H and SSEA3 and uses thereof in cancer treatment
|
|
KR101324109B1
(ko)
|
2008-06-16 |
2013-10-31 |
아카데미아 시니카 |
Ｇｌｏｂｏ ｈ 및 그의 절편들에 대한 항체의 양에 따른 암 진단방법
|
|
JP2010014691A
(ja)
|
2008-06-20 |
2010-01-21 |
Igaku Seibutsugaku Kenkyusho:Kk |
腹水中のメソテリン及び／又は巨核球増強因子を検出するための方法、キット、試薬及び装置
|
|
US7928077B2
(en)
|
2008-07-11 |
2011-04-19 |
Academia Sinica |
Alpha-galactosyl ceramide analogs and their use as immunotherapies
|
|
WO2010009271A2
(en)
|
2008-07-15 |
2010-01-21 |
Academia Sinica |
Glycan arrays on ptfe-like aluminum coated glass slides and related methods
|
|
US20100022916A1
(en)
|
2008-07-24 |
2010-01-28 |
Javanbakhsh Esfandiari |
Method and Apparatus for Collecting and Preparing Biological Samples for Testing
|
|
GB0816679D0
(en)
|
2008-09-11 |
2008-10-22 |
Univ Bath |
Compounds for treating viral infections
|
|
EP2411528B1
(en)
|
2009-03-27 |
2015-09-02 |
Academia Sinica |
Alpha-selective sialyl phosphate donors for preparation of sialosides and sialoside arrays for influenza virus detection
|
|
TWI583393B
(zh)
*
|
2009-06-16 |
2017-05-21 |
中央研究院 |
免疫原性組合物、包含其之疫苗與治療劑及其用途
|
|
WO2011005756A1
(en)
|
2009-07-06 |
2011-01-13 |
Puretech Ventures, Llc |
Delivery of agents targeted to microbiota niches
|
|
BR112012001061B8
(pt)
|
2009-07-15 |
2021-05-25 |
Univ British Columbia |
glicosídeos 2,3-fluorados como inibidores de neuraminidase, seu método de preparação, composição farmacêutica que os compreende e embalagem comercial
|
|
US20120171201A1
(en)
|
2009-07-22 |
2012-07-05 |
Enzon Pharmaceuticals, Inc. |
Methods of treating her2 positive cancer with her2 receptor antagonist in combination with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
|
|
WO2011031236A1
(en)
|
2009-09-14 |
2011-03-17 |
Thailand Excellence Center For Tissue Engineering |
Phytochemical compositions including xanthones for anti-inflammatory, anti-cytokine storm, and other uses
|
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
JPWO2011074621A1
(ja)
|
2009-12-18 |
2013-04-25 |
株式会社医学生物学研究所 |
メソセリン（ｍｓｌｎ）に対する抗体及びその用途
|
|
EP2347769A1
(en)
|
2010-01-20 |
2011-07-27 |
Glycotope GmbH |
Cancer stem cell markers and uses thereof
|
|
SG182823A1
(en)
|
2010-02-11 |
2012-09-27 |
Alexion Pharma Inc |
Therapeutic methods using an ti-cd200 antibodies
|
|
BR112012020882A2
(pt)
|
2010-02-24 |
2015-11-03 |
Merck Sharp & Dohme |
métodos para produzir uma glicoproteína heteróloga e para produzir uma composição de glicoproteína, célula hospedeira, composição de glicoproteína, e, uso da pichia pastoris recombinante.
|
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
|
CA3122219A1
(en)
|
2010-04-16 |
2011-10-20 |
The Children's Hospital Corporation |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
|
AU2011250970B2
(en)
|
2010-05-10 |
2016-12-15 |
Sinica, Academia |
Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses
|
|
WO2011145957A1
(en)
|
2010-05-20 |
2011-11-24 |
Auckland Uniservices Limited |
Agents and methods for detection and/or imaging of hypoxia
|
|
JP5956982B2
(ja)
|
2010-05-27 |
2016-07-27 |
メルク・シャープ・エンド・ドーム・コーポレイション |
改善された特性を有する抗体の製造方法
|
|
GB201015569D0
(en)
|
2010-09-16 |
2010-10-27 |
Medical Res Council |
Blood assay for prions
|
|
WO2012082635A1
(en)
|
2010-12-13 |
2012-06-21 |
Ancora Pharmaceuticals, Inc. |
Synthetic oligosaccharide group a streptococcus
|
|
AU2012204336C1
(en)
|
2011-01-05 |
2017-08-03 |
National Taiwan University |
Methods for preparation of glycosphingolipids and uses thereof
|
|
US10851174B2
(en)
|
2011-03-03 |
2020-12-01 |
University Of Maryland, Baltimore |
Core fucosylated glycopeptides and glycoproteins: chemoenzymatic synthesis and uses thereof
|
|
EP2714732A4
(en)
|
2011-05-25 |
2014-12-10 |
Merck Sharp & Dohme |
PROCESS FOR PREPARING FC-CONTAINING POLYPEPTIDES WITH IMPROVED PROPERTIES
|
|
LT3418300T
(lt)
|
2011-07-18 |
2021-01-11 |
Institute For Research In Biomedicine |
Neutralizuojantys antikūnai prieš gripo virusą a ir jų panaudojimas
|
|
EP2742049A1
(en)
|
2011-08-12 |
2014-06-18 |
Nissan Chemical Industries, Ltd. |
Tricyclic heterocyclic compounds and jak inhibitors
|
|
US20140302028A1
(en)
|
2011-11-18 |
2014-10-09 |
Merck Sharp & Dohme Corp. |
Fc containing polypeptides having increased anti-inflammatory properties and increased fcrn binding
|
|
EP2604281B1
(en)
|
2011-12-14 |
2014-07-30 |
Centre National de la Recherche Scientifique (CNRS) |
Clicked somatostatin conjugated analogs for biological applications
|
|
WO2013106937A1
(en)
|
2012-01-19 |
2013-07-25 |
The University Of British Columbia |
3' equatorial-fluorine-substituted neuraminidase inhibitor compounds, compositions and methods for the use thereof as anti-virals
|
|
WO2013120066A1
(en)
|
2012-02-10 |
2013-08-15 |
University Of Maryland, Baltimore |
Chemoenzymatic glycoengineering of antibodies and fc fragments thereof
|
|
US9846160B2
(en)
|
2012-02-27 |
2017-12-19 |
Board Of Regents, The University Of Texas Systems |
Ganglioside GD2 as a marker and target on cancer stem cells
|
|
BR112014024494A2
(pt)
|
2012-04-02 |
2017-08-08 |
Merrimack Pharmaceuticals Inc |
dosagem e administração de anticorpos anti-igf-1r e anti-erbb3 monoespecíficos e biespecíficos
|
|
WO2013151649A1
(en)
|
2012-04-04 |
2013-10-10 |
Sialix Inc |
Glycan-interacting compounds
|
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
|
EP2855745A4
(en)
|
2012-06-01 |
2016-01-20 |
Momenta Pharmaceuticals Inc |
METHODS RELATING TO ADALIMUM AB
|
|
JP6302909B2
(ja)
|
2012-08-18 |
2018-03-28 |
アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ |
シアリダーゼの同定および画像化のための細胞透過性プローブ
|
|
TWI563092B
(en)
|
2012-08-20 |
2016-12-21 |
Academia Sinica |
Large scale enzymatic synthesis of oligosaccharides
|
|
US9547009B2
(en)
|
2012-08-21 |
2017-01-17 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
|
KR20210090298A
(ko)
|
2012-10-30 |
2021-07-19 |
에스퍼란스 파마슈티컬스, 인코포레이티드 |
항체/약물 컨쥬게이트 및 이의 사용 방법
|
|
US20150284452A1
(en)
|
2012-11-13 |
2015-10-08 |
Iogenetics, Llc |
Antimicrobial compositions
|
|
EP3013365B1
(en)
|
2013-06-26 |
2019-06-05 |
Academia Sinica |
Rm2 antigens and use thereof
|
|
US9981030B2
(en)
*
|
2013-06-27 |
2018-05-29 |
Academia Sinica |
Glycan conjugates and use thereof
|
|
TWI599370B
(zh)
|
2013-07-26 |
2017-09-21 |
中央研究院 |
靈芝多醣誘發之抗體介導抗腫瘤活性
|
|
WO2015035337A1
(en)
|
2013-09-06 |
2015-03-12 |
Academia Sinica |
HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS
|
|
US20160201132A1
(en)
|
2013-09-12 |
2016-07-14 |
Teva Pharmaceutical Industries Ltd. |
Gene expression biomarkers of laquinimod responsiveness
|
|
WO2015054039A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Fc CONTAINING POLYPEPTIDES HAVING INCREASED BINDING TO FcGammaRIIB
|
|
KR20160104727A
(ko)
|
2014-01-16 |
2016-09-05 |
아카데미아 시니카 |
암의 치료 및 검출을 위한 조성물 및 방법
|
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
CN106415244B
(zh)
|
2014-03-27 |
2020-04-24 |
中央研究院 |
反应性标记化合物及其用途
|
|
CA2950440A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Anti-her2 glycoantibodies and uses thereof
|
|
TWI654202B
(zh)
|
2014-05-27 |
2019-03-21 |
中央研究院 |
增進抗體功效之通用糖型之組合物及方法
|
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
KR20220151036A
(ko)
|
2014-05-27 |
2022-11-11 |
아카데미아 시니카 |
항-ｃｄ20 글리코항체 및 이의 용도
|
|
TWI732738B
(zh)
|
2014-05-28 |
2021-07-11 |
中央研究院 |
抗TNF-α醣抗體及其用途
|
|
WO2016029071A1
(en)
*
|
2014-08-22 |
2016-02-25 |
Academia Sinica |
Novel glycan conjugates and use thereof
|
|
KR102422375B1
(ko)
|
2014-09-08 |
2022-07-18 |
아카데미아 시니카 |
당지질을 사용한 인간 iNKT 세포 활성화
|
|
KR102559731B1
(ko)
|
2014-09-12 |
2023-07-25 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
대음세포작용 인간 항-cd46 항체 및 표적화된 암 치료제
|
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
|
US20170283878A1
(en)
|
2015-12-11 |
2017-10-05 |
Academia Sinica |
Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers
|