JP2016539172A5 - - Google Patents
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- Publication number
- JP2016539172A5 JP2016539172A5 JP2016536849A JP2016536849A JP2016539172A5 JP 2016539172 A5 JP2016539172 A5 JP 2016539172A5 JP 2016536849 A JP2016536849 A JP 2016536849A JP 2016536849 A JP2016536849 A JP 2016536849A JP 2016539172 A5 JP2016539172 A5 JP 2016539172A5
- Authority
- JP
- Japan
- Prior art keywords
- ganglioside
- carbohydrate
- cancer
- pharmaceutical composition
- multimer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- -1 ganglioside carbohydrate Chemical class 0.000 claims 33
- 206010028980 Neoplasm Diseases 0.000 claims 13
- 201000011510 cancer Diseases 0.000 claims 12
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 125000003118 aryl group Chemical group 0.000 claims 3
- 125000000041 C6-C10 aryl group Chemical group 0.000 claims 2
- 125000002421 ganglioside group Chemical group 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 208000032612 Glial tumor Diseases 0.000 claims 1
- 206010018338 Glioma Diseases 0.000 claims 1
- 206010029260 Neuroblastoma Diseases 0.000 claims 1
- 206010041067 Small cell lung cancer Diseases 0.000 claims 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 claims 1
- 150000002270 gangliosides Chemical class 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 230000005847 immunogenicity Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 229920001542 oligosaccharide Polymers 0.000 claims 1
- 150000002482 oligosaccharides Chemical class 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims 1
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361912684P | 2013-12-06 | 2013-12-06 | |
| US61/912,684 | 2013-12-06 | ||
| PCT/CA2014/051165 WO2015081438A1 (en) | 2013-12-06 | 2014-12-04 | Anti-ganglioside compound for targeting cancer and generating antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016539172A JP2016539172A (ja) | 2016-12-15 |
| JP2016539172A5 true JP2016539172A5 (enExample) | 2017-03-09 |
Family
ID=53272688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536849A Pending JP2016539172A (ja) | 2013-12-06 | 2014-12-04 | 癌標的化及び抗体作製のための抗ガングリオシド化合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10363305B2 (enExample) |
| EP (2) | EP3077405B1 (enExample) |
| JP (1) | JP2016539172A (enExample) |
| CN (1) | CN106414472A (enExample) |
| CA (1) | CA2968995A1 (enExample) |
| ES (1) | ES2904533T3 (enExample) |
| WO (1) | WO2015081438A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018112669A1 (en) * | 2016-12-23 | 2018-06-28 | Realist Pharma, Inc. | Ganglioside carbohydrate structures and uses thereof |
| KR20230155419A (ko) * | 2020-10-05 | 2023-11-10 | 에이오에이 디엑스 | 암 진단을 위한 조성물 및 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU221420B1 (en) * | 1993-01-22 | 2002-09-28 | Sloan Kettering Inst Cancer | Ganglioside-protein conjugate vaccines |
| US7422733B2 (en) * | 2000-11-29 | 2008-09-09 | Bracco International B.V. | Linkable sialyl Lewis X analogs |
| JP2004534088A (ja) * | 2001-07-06 | 2004-11-11 | スローン−ケッタリング・インスティテュート・フォア・キャンサー・リサーチ | 癌のための多価コンジュゲートワクチン |
| JP2003073397A (ja) | 2001-08-30 | 2003-03-12 | Wakamoto Pharmaceut Co Ltd | 合成ムチン |
| WO2004041310A1 (en) * | 2002-11-08 | 2004-05-21 | Danmarks Fødevareforskning | Preparation of chemically well-defined carbohydrate dendrimer conjugates |
| JP4742339B2 (ja) | 2005-06-14 | 2011-08-10 | 独立行政法人産業技術総合研究所 | シアル酸含有３糖化合物、それを用いるサーズウイルスまたはサーズスパイク蛋白質の検出 |
| US20090181362A1 (en) * | 2005-09-02 | 2009-07-16 | Yasuo Suzuki | Method for determination of recognition specificity of virus for receptor sugar chain |
| JP2008031156A (ja) | 2006-07-07 | 2008-02-14 | National Univ Corp Shizuoka Univ | 抗ウイルス剤 |
-
2014
- 2014-12-04 JP JP2016536849A patent/JP2016539172A/ja active Pending
- 2014-12-04 WO PCT/CA2014/051165 patent/WO2015081438A1/en not_active Ceased
- 2014-12-04 EP EP14868142.2A patent/EP3077405B1/en active Active
- 2014-12-04 CN CN201480073838.1A patent/CN106414472A/zh active Pending
- 2014-12-04 CA CA2968995A patent/CA2968995A1/en not_active Abandoned
- 2014-12-04 US US15/101,428 patent/US10363305B2/en active Active
- 2014-12-04 ES ES14868142T patent/ES2904533T3/es active Active
- 2014-12-04 EP EP21199178.1A patent/EP3957327A1/en active Pending
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