JP2016519107A5 - - Google Patents

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Publication number
JP2016519107A5
JP2016519107A5 JP2016507634A JP2016507634A JP2016519107A5 JP 2016519107 A5 JP2016519107 A5 JP 2016519107A5 JP 2016507634 A JP2016507634 A JP 2016507634A JP 2016507634 A JP2016507634 A JP 2016507634A JP 2016519107 A5 JP2016519107 A5 JP 2016519107A5
Authority
JP
Japan
Prior art keywords
hypoxia
predetermined value
cancer
degree
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016507634A
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English (en)
Japanese (ja)
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JP2016519107A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/033491 external-priority patent/WO2014169035A1/en
Publication of JP2016519107A publication Critical patent/JP2016519107A/ja
Publication of JP2016519107A5 publication Critical patent/JP2016519107A5/ja
Pending legal-status Critical Current

Links

JP2016507634A 2013-04-10 2014-04-09 Ｔｈ−３０２抗癌療法のための予測および応答のバイオマーカー Pending JP2016519107A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361810643P 2013-04-10 2013-04-10
US61/810,643 2013-04-10
PCT/US2014/033491 WO2014169035A1 (en) 2013-04-10 2014-04-09 Predictive and response biomarker for th-302 anti-cancer therapy

Publications (2)

Publication Number Publication Date
JP2016519107A JP2016519107A (ja) 2016-06-30
JP2016519107A5 true JP2016519107A5 (enExample) 2017-06-01

Family

ID=51689977

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016507634A Pending JP2016519107A (ja) 2013-04-10 2014-04-09 Ｔｈ−３０２抗癌療法のための予測および応答のバイオマーカー

Country Status (4)

Country Link
US (1) US20160296538A1 (enExample)
EP (1) EP2983591A4 (enExample)
JP (1) JP2016519107A (enExample)
WO (1) WO2014169035A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10071109B2 (en) 2013-11-06 2018-09-11 Molecular Templates, Inc. Predictive biomarker for hypoxia-activated prodrug therapy
EP3226869A4 (en) * 2014-12-03 2018-07-18 Auckland UniServices, Ltd. Kinase inhibitor prodrug for the treatment of cancer
US11504075B2 (en) * 2017-12-20 2022-11-22 University Health Network System, methods, and devices for calculating hypoxic fraction and equilibration rate of small molecular weight tracers using dynamic imaging
WO2023025291A1 (zh) 2021-08-27 2023-03-02 深圳艾欣达伟医药科技有限公司 冻干制剂溶液及冻干制剂、方法和用途
JP7762796B2 (ja) 2021-08-27 2025-10-30 アセンタウィッツ ファーマシューティカルズ リミテッド Ｐａｒｐ阻害剤に耐性のある患者のｔｈ－３０２による治療
CN118829436A (zh) 2022-03-15 2024-10-22 深圳艾欣达伟医药科技有限公司 治疗brca突变癌症患者的方法
US20250295677A1 (en) 2022-04-15 2025-09-25 Ascentawits Pharmaceuticals, Ltd. Method for treating cancer by using th-302 alone or in combination with parp inhibitor
WO2023226959A1 (zh) 2022-05-23 2023-11-30 深圳艾欣达伟医药科技有限公司 烷化剂前药与细胞周期抑制剂联用治疗癌症的方法
WO2024061346A1 (zh) 2022-09-22 2024-03-28 深圳艾欣达伟医药科技有限公司 乏氧激活的化合物在制备治疗癌症患者的药物中的用途
WO2024179467A1 (zh) * 2023-02-27 2024-09-06 深圳艾欣达伟医药科技有限公司 溶液、冻干制剂、冻干制剂单位包装、注射液及注射液配制方法
AU2024317010A1 (en) 2023-07-28 2026-02-26 Ascentawits Pharmaceuticals, Ltd. Treatment of p53 gene mutation or defect negative cancer and tumor patients

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2441228A1 (en) * 2001-03-23 2002-10-03 Aphton Corporation Combination treatment of pancreatic cancer
US20070117784A1 (en) * 2005-03-04 2007-05-24 Novacea, Inc. Treatment of hyperproliferative diseases with anthraquinones
WO2010048330A1 (en) * 2008-10-21 2010-04-29 Threshold Pharmaceuticals, Inc. Treatment of cancer using hypoxia activated prodrugs
AU2011276590A1 (en) * 2010-06-28 2013-01-31 Threshold Pharmaceuticals, Inc. Treatment of blood cancer
MX2012014428A (es) * 2010-07-12 2013-03-05 Threshold Pharmaceuticals Inc Administracion de profarmacos activados por hipoxia y de agentes antiangiogenicos para el tratamiento de cancer.
US10357577B2 (en) * 2010-07-16 2019-07-23 Auckland Uniservices Limited Bacterial nitroreductase enzymes and methods relating thereto

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