JP2018500897A5 - - Google Patents
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- JP2018500897A5 JP2018500897A5 JP2017530596A JP2017530596A JP2018500897A5 JP 2018500897 A5 JP2018500897 A5 JP 2018500897A5 JP 2017530596 A JP2017530596 A JP 2017530596A JP 2017530596 A JP2017530596 A JP 2017530596A JP 2018500897 A5 JP2018500897 A5 JP 2018500897A5
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- genetically modified
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- animal
- hla
- Prior art date
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462090037P | 2014-12-10 | 2014-12-10 | |
| US62/090,037 | 2014-12-10 | ||
| US201562253493P | 2015-11-10 | 2015-11-10 | |
| US62/253,493 | 2015-11-10 | ||
| PCT/US2015/065029 WO2016094679A1 (en) | 2014-12-10 | 2015-12-10 | Genetically modified cells, tissues, and organs for treating disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020026602A Division JP2020096632A (ja) | 2014-12-10 | 2020-02-19 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018500897A JP2018500897A (ja) | 2018-01-18 |
| JP2018500897A5 true JP2018500897A5 (enExample) | 2019-01-24 |
| JP6830437B2 JP6830437B2 (ja) | 2021-02-17 |
Family
ID=56108194
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017530596A Active JP6830437B2 (ja) | 2014-12-10 | 2015-12-10 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
| JP2020026602A Pending JP2020096632A (ja) | 2014-12-10 | 2020-02-19 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
| JP2021097515A Pending JP2021126129A (ja) | 2014-12-10 | 2021-06-10 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
| JP2021114775A Pending JP2021166542A (ja) | 2014-12-10 | 2021-07-12 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020026602A Pending JP2020096632A (ja) | 2014-12-10 | 2020-02-19 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
| JP2021097515A Pending JP2021126129A (ja) | 2014-12-10 | 2021-06-10 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
| JP2021114775A Pending JP2021166542A (ja) | 2014-12-10 | 2021-07-12 | 疾患を処置するための遺伝子改変された細胞、組織および臓器 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US9888673B2 (enExample) |
| EP (1) | EP3229586B1 (enExample) |
| JP (4) | JP6830437B2 (enExample) |
| KR (1) | KR102656470B1 (enExample) |
| CN (3) | CN107249318A (enExample) |
| AU (5) | AU2015360502A1 (enExample) |
| CA (1) | CA2969847A1 (enExample) |
| HK (1) | HK1245010A1 (enExample) |
| WO (1) | WO2016094679A1 (enExample) |
Families Citing this family (109)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013066438A2 (en) | 2011-07-22 | 2013-05-10 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9737604B2 (en) | 2013-09-06 | 2017-08-22 | President And Fellows Of Harvard College | Use of cationic lipids to deliver CAS9 |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US10231817B2 (en) | 2013-09-24 | 2019-03-19 | Giner Life Sciences, Inc. | System for gas treatment of a cell implant |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| CA2935960C (en) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Acoustophoresis device with dual acoustophoretic chamber |
| AU2015298571B2 (en) | 2014-07-30 | 2020-09-03 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| AU2015360502A1 (en) | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| EP3274010B1 (en) * | 2015-03-27 | 2019-10-02 | Eliaz Therapeutics, Inc. | Patient selective apheresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US12043852B2 (en) | 2015-10-23 | 2024-07-23 | President And Fellows Of Harvard College | Evolved Cas9 proteins for gene editing |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| KR20230110373A (ko) * | 2016-06-14 | 2023-07-21 | 리전츠 오브 더 유니버스티 오브 미네소타 | 질환을 치료하기 위한 유전적으로 변형된 세포, 조직,및 장기 |
| CA3028786A1 (en) | 2016-07-26 | 2018-02-01 | The University Of North Carolina At Chapel Hill | Vector-mediated immune tolerance in the eye |
| KR20250103795A (ko) | 2016-08-03 | 2025-07-07 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 아데노신 핵염기 편집제 및 그의 용도 |
| CN109804066A (zh) | 2016-08-09 | 2019-05-24 | 哈佛大学的校长及成员们 | 可编程cas9-重组酶融合蛋白及其用途 |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| AU2017342543B2 (en) | 2016-10-14 | 2024-06-27 | President And Fellows Of Harvard College | AAV delivery of nucleobase editors |
| CN110494543A (zh) | 2016-10-19 | 2019-11-22 | 弗洛设计声能学公司 | 通过声学的亲和细胞提取 |
| US11033666B2 (en) | 2016-11-15 | 2021-06-15 | Giner Life Sciences, Inc. | Percutaneous gas diffusion device suitable for use with a subcutaneous implant |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| KR20240128814A (ko) * | 2017-01-10 | 2024-08-27 | 프레시전 인코포레이티드 | 신규의 유전자 스위치 발현 시스템을 통한 폴리펩티드의 발현 조절 |
| BR112019015342A2 (pt) * | 2017-01-30 | 2020-03-10 | The Board Of Trustees Of The Leland Stanford Junior University | Regime de condicionamento não genotóxico para o transplante de células-tronco |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| EP3592381A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Cancer vaccine |
| KR20190127797A (ko) | 2017-03-10 | 2019-11-13 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 시토신에서 구아닌으로의 염기 편집제 |
| CN108467873B (zh) | 2017-03-17 | 2020-03-13 | 百奥赛图江苏基因生物技术有限公司 | 一种cd132基因缺失的免疫缺陷动物模型的制备方法及应用 |
| EP3601528A4 (en) * | 2017-03-20 | 2021-05-05 | Washington University | CELLS AND METHODS OF USE AND PRODUCTION OF THEM |
| CA3057192A1 (en) | 2017-03-23 | 2018-09-27 | President And Fellows Of Harvard College | Nucleobase editors comprising nucleic acid programmable dna binding proteins |
| WO2018177441A1 (en) | 2017-03-31 | 2018-10-04 | Beijing Biocytogen Co., Ltd | GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC SIRPα |
| CN108588126B (zh) | 2017-03-31 | 2020-04-10 | 北京百奥赛图基因生物技术有限公司 | Cd47基因人源化改造动物模型的制备方法及应用 |
| US12058986B2 (en) | 2017-04-20 | 2024-08-13 | Egenesis, Inc. | Method for generating a genetically modified pig with inactivated porcine endogenous retrovirus (PERV) elements |
| WO2018204867A1 (en) | 2017-05-04 | 2018-11-08 | Giner, Inc. | Robust, implantable gas delivery device and methods, systems and devices including same |
| WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
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