ATE313256T1 - Transgene schweine - Google Patents
Transgene schweineInfo
- Publication number
- ATE313256T1 ATE313256T1 AT98929756T AT98929756T ATE313256T1 AT E313256 T1 ATE313256 T1 AT E313256T1 AT 98929756 T AT98929756 T AT 98929756T AT 98929756 T AT98929756 T AT 98929756T AT E313256 T1 ATE313256 T1 AT E313256T1
- Authority
- AT
- Austria
- Prior art keywords
- organs
- tissues
- transgenic pigs
- transgenic
- regulator
- Prior art date
Links
- 230000009261 transgenic effect Effects 0.000 title abstract 3
- 241000282887 Suidae Species 0.000 title 1
- 210000000056 organ Anatomy 0.000 abstract 2
- 102100025680 Complement decay-accelerating factor Human genes 0.000 abstract 1
- 241000282412 Homo Species 0.000 abstract 1
- 101000856022 Homo sapiens Complement decay-accelerating factor Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 210000003556 vascular endothelial cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Environmental Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Confectionery (AREA)
- Seasonings (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20523597 | 1997-07-14 | ||
PCT/JP1998/002927 WO1999003336A1 (fr) | 1997-07-14 | 1998-06-30 | Mammiferes transgeniques |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE313256T1 true ATE313256T1 (de) | 2006-01-15 |
Family
ID=16503653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98929756T ATE313256T1 (de) | 1997-07-14 | 1998-06-30 | Transgene schweine |
Country Status (7)
Country | Link |
---|---|
US (1) | US6825395B1 (de) |
EP (1) | EP1004238B1 (de) |
AT (1) | ATE313256T1 (de) |
AU (1) | AU7935598A (de) |
CA (1) | CA2297105A1 (de) |
DE (1) | DE69832883T2 (de) |
WO (1) | WO1999003336A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE474590T1 (de) * | 1999-05-10 | 2010-08-15 | Paolo Brenner | Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen |
US7560279B2 (en) * | 2002-03-25 | 2009-07-14 | Hiroshima Industrial Promotion Organization | Method of proliferating human hepatocytes and method for obtaining human hepatocytes |
US20070113297A1 (en) * | 2005-09-13 | 2007-05-17 | Yongguang Yang | Methods and compositions for inhibition of immune responses |
US9420770B2 (en) | 2009-12-01 | 2016-08-23 | Indiana University Research & Technology Corporation | Methods of modulating thrombocytopenia and modified transgenic pigs |
WO2012078968A2 (en) | 2010-12-10 | 2012-06-14 | Lifeline Scientific, Inc. | Machine perfusion with complement inhibitors |
EP3229586A4 (de) | 2014-12-10 | 2018-10-24 | Regents of the University of Minnesota | Genetisch modifizierte zellen, gewebe und organe zur behandlung von krankheiten |
CN116555353A (zh) | 2017-04-20 | 2023-08-08 | E开创生物技术股份有限公司 | 产生基因修改的动物的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0495852T3 (da) | 1989-10-12 | 1996-07-15 | Imutran Ltd | Modificeret biologisk materiale |
CA2113089C (en) | 1991-07-15 | 2007-11-06 | Peter J. Sims | Universal donor cells |
DE69634731D1 (de) * | 1995-06-20 | 2005-06-16 | Nippon Meat Packers | Dna, die für einen komplement inhibitor vom schwein kodiert |
US6166288A (en) * | 1995-09-27 | 2000-12-26 | Nextran Inc. | Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor |
ATE314466T1 (de) * | 1996-05-17 | 2006-01-15 | Nippon Meat Packers | Promotoren von komplementinhibitoren des schweines. |
-
1998
- 1998-06-30 US US09/462,740 patent/US6825395B1/en not_active Expired - Lifetime
- 1998-06-30 CA CA002297105A patent/CA2297105A1/en not_active Abandoned
- 1998-06-30 WO PCT/JP1998/002927 patent/WO1999003336A1/ja active IP Right Grant
- 1998-06-30 AU AU79355/98A patent/AU7935598A/en not_active Abandoned
- 1998-06-30 DE DE69832883T patent/DE69832883T2/de not_active Expired - Lifetime
- 1998-06-30 AT AT98929756T patent/ATE313256T1/de not_active IP Right Cessation
- 1998-06-30 EP EP98929756A patent/EP1004238B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6825395B1 (en) | 2004-11-30 |
AU7935598A (en) | 1999-02-10 |
DE69832883T2 (de) | 2006-08-24 |
WO1999003336A1 (fr) | 1999-01-28 |
DE69832883D1 (de) | 2006-01-26 |
EP1004238A4 (de) | 2000-12-06 |
EP1004238A1 (de) | 2000-05-31 |
EP1004238B1 (de) | 2005-12-21 |
CA2297105A1 (en) | 1999-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |