DE60002603D1 - Phosphor-enthaltende dendrimere als transfektionsagente - Google Patents
Phosphor-enthaltende dendrimere als transfektionsagenteInfo
- Publication number
- DE60002603D1 DE60002603D1 DE60002603T DE60002603T DE60002603D1 DE 60002603 D1 DE60002603 D1 DE 60002603D1 DE 60002603 T DE60002603 T DE 60002603T DE 60002603 T DE60002603 T DE 60002603T DE 60002603 D1 DE60002603 D1 DE 60002603D1
- Authority
- DE
- Germany
- Prior art keywords
- phosphorus
- transfection agents
- containing dendrimers
- agents
- dendrimers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2479—Compounds containing the structure P(=X)n-N-acyl, P(=X)n-N-heteroatom, P(=X)n-N-CN (X = O, S, Se; n = 0, 1)
- C07F9/2491—Compounds containing the structure P(=X)n-N-acyl, P(=X)n-N-heteroatom, P(=X)n-N-CN (X = O, S, Se; n = 0, 1) containing the structure P(=X)n-N-N (X = O, S, Se; n = 0, 1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
- C07F9/65815—Cyclic phosphazenes [P=N-]n, n>=3 n = 3
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9914864 | 1999-11-25 | ||
FR9914864A FR2801592B1 (fr) | 1999-11-25 | 1999-11-25 | Dendrimeres phosphores et leurs applications comme agents de transfection |
PCT/FR2000/003261 WO2001038335A1 (fr) | 1999-11-25 | 2000-11-23 | Dendrimeres phosphores comme agents de transfevtion |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60002603D1 true DE60002603D1 (de) | 2003-06-12 |
DE60002603T2 DE60002603T2 (de) | 2004-02-26 |
Family
ID=9552551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60002603T Expired - Lifetime DE60002603T2 (de) | 1999-11-25 | 2000-11-23 | Phosphor-enthaltende dendrimere als transfektionsagente |
Country Status (9)
Country | Link |
---|---|
US (1) | US6969528B1 (de) |
EP (1) | EP1232165B1 (de) |
JP (1) | JP2003514912A (de) |
AT (1) | ATE239749T1 (de) |
CA (1) | CA2392697A1 (de) |
DE (1) | DE60002603T2 (de) |
ES (1) | ES2194794T3 (de) |
FR (1) | FR2801592B1 (de) |
WO (1) | WO2001038335A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2834988B1 (fr) * | 2002-01-21 | 2005-07-08 | Centre Nat Rech Scient | Utilisation de dendrimeres phosphores comme medicaments |
FR2838737B1 (fr) | 2002-04-23 | 2006-02-03 | Centre Nat Rech Scient | Supports solides fonctionnalises par des dendrimeres phosphores, leur procede de preparation et applications |
FR2851565B1 (fr) * | 2003-02-26 | 2005-04-01 | Commissariat Energie Atomique | Dendrimeres phosphores, leur procede de preparation et leur utilisation pour l'extraction des actinides et des lanthanides |
FR2873715B1 (fr) * | 2004-07-30 | 2006-11-17 | Centre Nat Rech Scient Cnrse | Utilisation de dendrimeres pour stimuler la croissance cellulaire |
FR2876916B1 (fr) * | 2004-10-25 | 2007-01-05 | Midi Pyrenees Incubateur | Produit implantable de surface fonctionnalisee au moyen de dendrimeres a terminaisons anioniques |
FR2896251B1 (fr) * | 2006-01-13 | 2008-04-11 | Univ Rennes 1 Etablissement Pu | Composes fluorescents dendrimeriques et utilisation de tels composes dans le cadre de procedes ou dispositifs multiphotoniques. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE258434T1 (de) * | 1993-07-14 | 2004-02-15 | Univ California | Sich selbst zusammensetzendes polynukleotid- abgabesystem, das dendrimer-polykationen enthält |
MX9504664A (es) * | 1994-03-07 | 1997-05-31 | Dow Chemical Co | Conjugados de dendrimeros bioactivos y/o dirigidos. |
US6440405B1 (en) * | 1999-06-07 | 2002-08-27 | University Of Delaware | Quaternary ammonium functionalized dendrimers and methods of use therefor |
-
1999
- 1999-11-25 FR FR9914864A patent/FR2801592B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-23 CA CA002392697A patent/CA2392697A1/en not_active Abandoned
- 2000-11-23 WO PCT/FR2000/003261 patent/WO2001038335A1/fr active IP Right Grant
- 2000-11-23 AT AT00985306T patent/ATE239749T1/de not_active IP Right Cessation
- 2000-11-23 ES ES00985306T patent/ES2194794T3/es not_active Expired - Lifetime
- 2000-11-23 JP JP2001540098A patent/JP2003514912A/ja active Pending
- 2000-11-23 US US10/130,739 patent/US6969528B1/en not_active Expired - Fee Related
- 2000-11-23 EP EP00985306A patent/EP1232165B1/de not_active Expired - Lifetime
- 2000-11-23 DE DE60002603T patent/DE60002603T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2194794T3 (es) | 2003-12-01 |
DE60002603T2 (de) | 2004-02-26 |
ATE239749T1 (de) | 2003-05-15 |
US6969528B1 (en) | 2005-11-29 |
CA2392697A1 (en) | 2001-05-31 |
WO2001038335A1 (fr) | 2001-05-31 |
EP1232165A1 (de) | 2002-08-21 |
EP1232165B1 (de) | 2003-05-07 |
JP2003514912A (ja) | 2003-04-22 |
FR2801592A1 (fr) | 2001-06-01 |
FR2801592B1 (fr) | 2002-02-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE340560T1 (de) | Verfahren und zusammensetzungen für nichtvirale gentherapie zur behandlung von hyperproliferativen krankheiten | |
CY1121447T1 (el) | Συνθεσεις για αυξηση δραστηριοτητας τελομερασης | |
BRPI0510206A (pt) | método de identificação de fenótipo, célula isolada, métodos de identificação de agentes, agentes, agentes terapêuticos, método de avaliação de agente terapêutico, composição farmacêutica, métodos de tratamento, prevenção ou melhoria de disfunções e métodos de modulação | |
WO2004011624A3 (en) | Double stranded rna structures and constructs, and methods for generating and using the same | |
WO2004035765A3 (en) | Double-stranded rna structures and constructs, and methods for generating and using the same | |
ATE445417T1 (de) | Ex vivo verfahren und zusammensetzungen zur nukleinsäureverabreichung | |
DE69922933D1 (de) | Anwendungen für humane nicht autologe, mesenchymale stammzellen | |
MX2007006524A (es) | Metodos para el suministro dirigido de material genetico al higado. | |
WO1999040197A3 (en) | Variants of the angiogenic factor vascular endothelial cell growth factor: vegf | |
WO2002020722A3 (en) | Methods and compositions for in vitro targeting | |
MX357691B (es) | Il-15 y il-15r-alfa mejoradas para expresion en celulas mamiferas. | |
TW200513532A (en) | VEGF traps and therapeutic uses thereof | |
BR9914643A (pt) | Vetores adeno-associados para expressão dofator viii por células alvo | |
WO1999064576A3 (en) | Human genes differentially expressed in colon cancer | |
EA199900262A1 (ru) | Ангиогенный фактор и способ его применения в лечении сердечно-сосудистого заболевания | |
WO2005030083A3 (en) | Methods and products which utilize n-acyl-l-aspartic acid | |
DK1526840T3 (da) | Nanopartikler til DNA administration til et målorgan | |
WO2005120588A3 (en) | Peptides delivered to cell nuclei | |
DE60002603D1 (de) | Phosphor-enthaltende dendrimere als transfektionsagente | |
NZ504445A (en) | Nucleic acid sequences of genes of the high mobility group proteins and their use in treating tumours, vascular disorders and as a contraceptive | |
DE50009365D1 (de) | Mittel zur behandlung maligner erkrankungen unter verwendung des proteins yb-1 | |
DE60129069D1 (de) | Hepatitis B Virus Vektoren für Gentherapie | |
ATE247978T1 (de) | Verwendung von ompa enterobakterproteinen um zielgerichtet antigen-präsentierende zellen anzusteuern | |
EP1277843A3 (de) | Neue humane Gene und Genexpressionsprodukte die in Zusammenhang mit Darmkrebs stehen | |
MX2007015127A (es) | Oligonucleotidos estimuladores de la proliferacion de celulas madre mesenquimatosas y sus usos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |