FR2873715B1 - Utilisation de dendrimeres pour stimuler la croissance cellulaire - Google Patents

Utilisation de dendrimeres pour stimuler la croissance cellulaire

Info

Publication number
FR2873715B1
FR2873715B1 FR0408426A FR0408426A FR2873715B1 FR 2873715 B1 FR2873715 B1 FR 2873715B1 FR 0408426 A FR0408426 A FR 0408426A FR 0408426 A FR0408426 A FR 0408426A FR 2873715 B1 FR2873715 B1 FR 2873715B1
Authority
FR
France
Prior art keywords
dendrimeres
cell growth
stimulating cell
stimulating
growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0408426A
Other languages
English (en)
Other versions
FR2873715A1 (fr
Inventor
Jean Pierre Majoral
Anne Marie Jeannine J Caminade
Jean Jacques Fournie
Laurent Griffe
Marsan Mary Poupot
Remy Poupot
Cedric Olivier Turrin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Solvay Solutions UK Ltd
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Rhodia Consumer Specialties Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0408426A priority Critical patent/FR2873715B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Sante et de la Recherche Medicale INSERM, Rhodia Consumer Specialties Ltd filed Critical Centre National de la Recherche Scientifique CNRS
Priority to JP2007523122A priority patent/JP2008508244A/ja
Priority to US11/658,858 priority patent/US8815834B2/en
Priority to CN2009102534500A priority patent/CN101724599B/zh
Priority to PCT/FR2005/002003 priority patent/WO2006024769A1/fr
Priority to EP05793666A priority patent/EP1771548B1/fr
Priority to BRPI0513972-4A priority patent/BRPI0513972A/pt
Priority to CN2005800330049A priority patent/CN101031638B/zh
Priority to ES05793666T priority patent/ES2389772T3/es
Priority to CA2576721A priority patent/CA2576721C/fr
Publication of FR2873715A1 publication Critical patent/FR2873715A1/fr
Application granted granted Critical
Publication of FR2873715B1 publication Critical patent/FR2873715B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4613—Natural-killer cells [NK or NK-T]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
    • C07F9/65815—Cyclic phosphazenes [P=N-]n, n>=3 n = 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
    • C07F9/65817—Cyclic phosphazenes [P=N-]n, n>=3 n = 4
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C09B69/109—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing other specific dyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
FR0408426A 2004-07-30 2004-07-30 Utilisation de dendrimeres pour stimuler la croissance cellulaire Expired - Fee Related FR2873715B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR0408426A FR2873715B1 (fr) 2004-07-30 2004-07-30 Utilisation de dendrimeres pour stimuler la croissance cellulaire
ES05793666T ES2389772T3 (es) 2004-07-30 2005-07-29 Utilización de dendrímeros para estimular el crecimiento celular
CN2009102534500A CN101724599B (zh) 2004-07-30 2005-07-29 树枝状聚合物刺激细胞生长的用途
PCT/FR2005/002003 WO2006024769A1 (fr) 2004-07-30 2005-07-29 Utilisation de dendrimeres pour stimuler la croissance cellulaire
EP05793666A EP1771548B1 (fr) 2004-07-30 2005-07-29 Utilisation de dendrimeres pour stimuler la croissance cellulaire
BRPI0513972-4A BRPI0513972A (pt) 2004-07-30 2005-07-29 uso de dendrìmeros para estimular o crescimento celular
JP2007523122A JP2008508244A (ja) 2004-07-30 2005-07-29 細胞成長を促進するデンドリマーの使用
US11/658,858 US8815834B2 (en) 2004-07-30 2005-07-29 Use of dendrimers to stimulate cell growth
CA2576721A CA2576721C (fr) 2004-07-30 2005-07-29 Utilisation de dendrimeres pour stimuler la croissance cellulaire
CN2005800330049A CN101031638B (zh) 2004-07-30 2005-07-29 树枝状聚合物刺激细胞生长的用途

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0408426A FR2873715B1 (fr) 2004-07-30 2004-07-30 Utilisation de dendrimeres pour stimuler la croissance cellulaire

Publications (2)

Publication Number Publication Date
FR2873715A1 FR2873715A1 (fr) 2006-02-03
FR2873715B1 true FR2873715B1 (fr) 2006-11-17

Family

ID=34947253

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0408426A Expired - Fee Related FR2873715B1 (fr) 2004-07-30 2004-07-30 Utilisation de dendrimeres pour stimuler la croissance cellulaire

Country Status (9)

Country Link
US (1) US8815834B2 (fr)
EP (1) EP1771548B1 (fr)
JP (1) JP2008508244A (fr)
CN (2) CN101031638B (fr)
BR (1) BRPI0513972A (fr)
CA (1) CA2576721C (fr)
ES (1) ES2389772T3 (fr)
FR (1) FR2873715B1 (fr)
WO (1) WO2006024769A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10106565B2 (en) 2008-08-01 2018-10-23 Centre National De La Recherche Scientifique Phosphorylated dendrimers as antiinflammatory drugs
WO2010013086A1 (fr) * 2008-08-01 2010-02-04 Centre National De La Recherche Scientifique Dendrimères phosphorylés en tant que médicaments anti-inflammatoires
KR20130033354A (ko) * 2010-02-08 2013-04-03 가부시키가이샤 니혼 바이오세라피 켄큐쇼 Ｎｋ세포 강화형 혈액제제의 제조 방법
WO2015021079A1 (fr) 2013-08-05 2015-02-12 Pacific Biosciences Of California, Inc. Composés réactifs fluorescents protégés
WO2016126941A1 (fr) 2015-02-04 2016-08-11 Pacific Biosciences Of California, Inc. Réactifs fluorescents protégés multimères
US10781483B2 (en) 2015-11-20 2020-09-22 Pacific Biosciences Of California, Inc. Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing
WO2017087974A1 (fr) * 2015-11-20 2017-05-26 Pacific Biosciences Of California, Inc. Réactifs marqués par un colorant protégés
US10676788B2 (en) 2015-11-20 2020-06-09 Pacific Biosciences Of California, Inc. Modified nucleotide reagents
CN107337806A (zh) * 2016-05-03 2017-11-10 广东广山新材料股份有限公司 含膦酸酯基的磷腈化合物、塑封料及复合金属基板
CN108976418B (zh) * 2018-07-19 2021-01-05 中国科学院宁波材料技术与工程研究所 一种基于呋喃衍生物和环三磷腈的三维结构阻燃剂及其制备方法
CN113077043B (zh) * 2021-03-17 2022-05-20 华中科技大学 基于改进图卷积网络的机床刀尖动力学特征预测方法
CN113527702B (zh) * 2021-07-15 2023-02-03 东华大学 一种两亲性含磷树冠大分子材料及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849452B1 (en) * 1998-03-03 2005-02-01 Institut Gustave Roussy Methods for activating natural killer (NK) cells and means for carrying out said methods
FR2801592B1 (fr) * 1999-11-25 2002-02-22 Centre Nat Rech Scient Dendrimeres phosphores et leurs applications comme agents de transfection
US20040120979A1 (en) * 2000-06-02 2004-06-24 Roessler Blake J. Delivery systems comprising biocompatible and bioerodable membranes
JP2004523624A (ja) * 2001-02-26 2004-08-05 デューク ユニバーシティ 新規なデンドリティックポリマー、およびその生物医学的使用
FR2838737B1 (fr) * 2002-04-23 2006-02-03 Centre Nat Rech Scient Supports solides fonctionnalises par des dendrimeres phosphores, leur procede de preparation et applications

Also Published As

Publication number Publication date
FR2873715A1 (fr) 2006-02-03
US8815834B2 (en) 2014-08-26
CA2576721A1 (fr) 2006-03-09
JP2008508244A (ja) 2008-03-21
ES2389772T3 (es) 2012-10-31
EP1771548B1 (fr) 2012-06-27
BRPI0513972A (pt) 2008-05-27
CN101031638B (zh) 2012-09-19
CN101031638A (zh) 2007-09-05
CA2576721C (fr) 2015-10-20
EP1771548A1 (fr) 2007-04-11
CN101724599B (zh) 2013-08-14
CN101724599A (zh) 2010-06-09
US20090142316A1 (en) 2009-06-04
WO2006024769A1 (fr) 2006-03-09

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