BRPI0513972A - uso de dendrìmeros para estimular o crescimento celular - Google Patents

uso de dendrìmeros para estimular o crescimento celular

Info

Publication number
BRPI0513972A
BRPI0513972A BRPI0513972-4A BRPI0513972A BRPI0513972A BR PI0513972 A BRPI0513972 A BR PI0513972A BR PI0513972 A BRPI0513972 A BR PI0513972A BR PI0513972 A BRPI0513972 A BR PI0513972A
Authority
BR
Brazil
Prior art keywords
stimulate cell
dendrimers
cell growth
growth
culture
Prior art date
Application number
BRPI0513972-4A
Other languages
English (en)
Inventor
Jean-Pierre Majoral
Anne-Marie Jeannine J Caminade
Jean-Jacques Fournie
Laurent Griffe
Mary Poupot-Marsan
Remy Poupot
Cedric-Olivier Turrin
Original Assignee
Centre Nat Rech Scient
Inst Nat Sante Rech Med
Rhodia Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Inst Nat Sante Rech Med, Rhodia Uk Ltd filed Critical Centre Nat Rech Scient
Publication of BRPI0513972A publication Critical patent/BRPI0513972A/pt

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4613—Natural-killer cells [NK or NK-T]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07—ORGANIC CHEMISTRY
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
    • C07F9/65815—Cyclic phosphazenes [P=N-]n, n>=3 n = 3
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
    • C07F9/65817—Cyclic phosphazenes [P=N-]n, n>=3 n = 4
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    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C09B69/109—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing other specific dyes
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

USO DE DENDRìMEROS PARA ESTIMULAR O CRESCIMENTO CELULAR. A presente invenção se relaciona com o uso de dendrímeros com terminações monofosfónicas ou bifosfónicas a fim de estimular o crescimento de culturas celulares ou para ativar as células na cultura.
BRPI0513972-4A 2004-07-30 2005-07-29 uso de dendrìmeros para estimular o crescimento celular BRPI0513972A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0408426A FR2873715B1 (fr) 2004-07-30 2004-07-30 Utilisation de dendrimeres pour stimuler la croissance cellulaire
PCT/FR2005/002003 WO2006024769A1 (fr) 2004-07-30 2005-07-29 Utilisation de dendrimeres pour stimuler la croissance cellulaire

Publications (1)

Publication Number Publication Date
BRPI0513972A true BRPI0513972A (pt) 2008-05-27

Family

ID=34947253

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513972-4A BRPI0513972A (pt) 2004-07-30 2005-07-29 uso de dendrìmeros para estimular o crescimento celular

Country Status (9)

Country Link
US (1) US8815834B2 (pt)
EP (1) EP1771548B1 (pt)
JP (1) JP2008508244A (pt)
CN (2) CN101031638B (pt)
BR (1) BRPI0513972A (pt)
CA (1) CA2576721C (pt)
ES (1) ES2389772T3 (pt)
FR (1) FR2873715B1 (pt)
WO (1) WO2006024769A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10106565B2 (en) 2008-08-01 2018-10-23 Centre National De La Recherche Scientifique Phosphorylated dendrimers as antiinflammatory drugs
US20100173871A1 (en) * 2008-08-01 2010-07-08 Centre National De La Recherche Scientifique Phosphorylated dendrimers as antiinflammatory drugs
US20120308986A1 (en) * 2010-02-08 2012-12-06 Biotherapy Institute Of Japan Method for producing nk cell-enriched blood product
EP3030683B1 (en) 2013-08-05 2022-03-02 Pacific Biosciences of California, Inc. Protected fluorescent reagent compounds
US10150872B2 (en) 2015-02-04 2018-12-11 Pacific Biosciences Of California, Inc. Multimeric protected fluorescent reagents
EP3376997A4 (en) 2015-11-20 2019-04-24 Pacific Biosciences Of California, Inc. NUCLEOTIDE ANALOGUES LABELED, REACTION MIXTURES AND METHODS AND SYSTEMS FOR SEQUENCING
US10676788B2 (en) 2015-11-20 2020-06-09 Pacific Biosciences Of California, Inc. Modified nucleotide reagents
WO2017087974A1 (en) * 2015-11-20 2017-05-26 Pacific Biosciences Of California, Inc. Protected dye-labeled reagents
CN107337806A (zh) * 2016-05-03 2017-11-10 广东广山新材料股份有限公司 含膦酸酯基的磷腈化合物、塑封料及复合金属基板
CN108976418B (zh) * 2018-07-19 2021-01-05 中国科学院宁波材料技术与工程研究所 一种基于呋喃衍生物和环三磷腈的三维结构阻燃剂及其制备方法
CN113077043B (zh) * 2021-03-17 2022-05-20 华中科技大学 基于改进图卷积网络的机床刀尖动力学特征预测方法
CN113527702B (zh) * 2021-07-15 2023-02-03 东华大学 一种两亲性含磷树冠大分子材料及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849452B1 (en) * 1998-03-03 2005-02-01 Institut Gustave Roussy Methods for activating natural killer (NK) cells and means for carrying out said methods
FR2801592B1 (fr) * 1999-11-25 2002-02-22 Centre Nat Rech Scient Dendrimeres phosphores et leurs applications comme agents de transfection
US20040120979A1 (en) * 2000-06-02 2004-06-24 Roessler Blake J. Delivery systems comprising biocompatible and bioerodable membranes
EP1370249A4 (en) * 2001-02-26 2006-05-03 Univ Duke NEW DENDRITIC POLYMERS AND ITS BIOMEDICAL APPLICATIONS
FR2838737B1 (fr) * 2002-04-23 2006-02-03 Centre Nat Rech Scient Supports solides fonctionnalises par des dendrimeres phosphores, leur procede de preparation et applications

Also Published As

Publication number Publication date
US8815834B2 (en) 2014-08-26
CA2576721A1 (fr) 2006-03-09
US20090142316A1 (en) 2009-06-04
FR2873715A1 (fr) 2006-02-03
CN101724599A (zh) 2010-06-09
CA2576721C (fr) 2015-10-20
CN101724599B (zh) 2013-08-14
JP2008508244A (ja) 2008-03-21
FR2873715B1 (fr) 2006-11-17
WO2006024769A1 (fr) 2006-03-09
CN101031638A (zh) 2007-09-05
EP1771548A1 (fr) 2007-04-11
CN101031638B (zh) 2012-09-19
EP1771548B1 (fr) 2012-06-27
ES2389772T3 (es) 2012-10-31

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements