DE60129069D1 - Hepatitis B Virus Vektoren für Gentherapie - Google Patents
Hepatitis B Virus Vektoren für GentherapieInfo
- Publication number
- DE60129069D1 DE60129069D1 DE60129069T DE60129069T DE60129069D1 DE 60129069 D1 DE60129069 D1 DE 60129069D1 DE 60129069 T DE60129069 T DE 60129069T DE 60129069 T DE60129069 T DE 60129069T DE 60129069 D1 DE60129069 D1 DE 60129069D1
- Authority
- DE
- Germany
- Prior art keywords
- hepatitis
- gene therapy
- virus vectors
- vivo
- deliver therapeutic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10141—Use of virus, viral particle or viral elements as a vector
- C12N2730/10143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2820/00—Vectors comprising a special origin of replication system
- C12N2820/60—Vectors comprising a special origin of replication system from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20000021070 | 2000-04-20 | ||
KR10-2001-0019645A KR100452718B1 (ko) | 2000-04-20 | 2001-04-12 | 유전자 치료용 재조합 b형 간염 바이러스 플라스미드 벡터 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60129069D1 true DE60129069D1 (de) | 2007-08-09 |
Family
ID=26637882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60129069T Expired - Lifetime DE60129069D1 (de) | 2000-04-20 | 2001-04-20 | Hepatitis B Virus Vektoren für Gentherapie |
Country Status (5)
Country | Link |
---|---|
US (1) | US7001760B2 (de) |
EP (1) | EP1149917B1 (de) |
JP (1) | JP3621355B2 (de) |
AT (1) | ATE365807T1 (de) |
DE (1) | DE60129069D1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7022830B2 (en) * | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
US7015317B2 (en) * | 2002-05-02 | 2006-03-21 | Abbott Laboratories | Polynucleotides for the detection and quantification of hepatitis B virus nucleic acids |
US20080096839A1 (en) * | 2005-03-09 | 2008-04-24 | Mogam Biotechnology Research Institute | Small Interfering Rna and Pharmaceutical Composition for Treatment of Hepatitis B Comprising the Same |
EP2426142A3 (de) | 2006-10-16 | 2012-06-13 | Genelux Corporation | Modifizierte Impfstoffvirusstämme zur Verwendung in einem Diagnose- und Therapieverfahren |
WO2009022236A2 (en) * | 2007-08-16 | 2009-02-19 | Tripep Ab | Immunogen platform |
US9096868B2 (en) * | 2007-09-14 | 2015-08-04 | Institut Pasteur | Polynucleotides allowing the expression and secretion of recombinant pseudo-virus containing foreign epitopes, their production, and use |
JP6486004B2 (ja) | 2011-02-10 | 2019-03-20 | ルプレヒト−カールス−ウニヴェルジテート ハイデルベルクRuprecht−Karls−Universitaet Heidelberg | 疎水性修飾ペプチドおよび肝臓特異的標的化のためのその使用 |
US10363323B2 (en) | 2011-02-10 | 2019-07-30 | Ruprecht-Karls-Universitat Heidelberg | Hydrophobic modified peptides for liver specific diagnosis |
WO2015057919A1 (en) * | 2013-10-18 | 2015-04-23 | The Johns Hopkins University | Transgenic hepatitis b virus (hbv): a new model of hbv infection identifies uqcr10 as a viral replication factor |
EP3189850A1 (de) | 2015-12-16 | 2017-07-12 | Ruprecht-Karls-Universität Heidelberg | Auf die leber gerichtete cyclische pres-peptide von hbv |
KR20220095183A (ko) * | 2019-08-29 | 2022-07-06 | 지 테크 바이오 엘엘씨 | 바이러스 감염을 치료하기 위한 조성물 및 방법 |
CN111575316A (zh) * | 2020-05-19 | 2020-08-25 | 东莞市松山湖中心医院(东莞市石龙人民医院、东莞市第三人民医院、东莞市心血管病研究所) | hKLK1重组质粒、高表达hKLK1的慢病毒颗粒及其构建方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU88257I2 (de) * | 1978-12-22 | 1994-02-03 | ||
EP0180012A1 (de) * | 1984-10-27 | 1986-05-07 | Wolfram H. Prof. Dr. Gerlich | Immunogene Polypeptidsequenz des Hepatitis B-Virus |
KR970007153B1 (ko) * | 1987-06-22 | 1997-05-03 | 메데바 홀딩스 비브이 | B형 간염 표면 항원 백신 |
FR2711670B1 (fr) * | 1993-10-22 | 1996-01-12 | Pasteur Institut | Vecteur nucléotidique, composition le contenant et vaccin pour l'immunisation à l'encontre d'une hépatite. |
US5744326A (en) * | 1996-03-11 | 1998-04-28 | The Immune Response Corporation | Use of viral CIS-acting post-transcriptional regulatory sequences to increase expression of intronless genes containing near-consensus splice sites |
US5981274A (en) | 1996-09-18 | 1999-11-09 | Tyrrell; D. Lorne J. | Recombinant hepatitis virus vectors |
GB9707221D0 (en) * | 1997-04-09 | 1997-05-28 | Univ Glasgow | Hepatitis B virus mutations |
-
2001
- 2001-04-19 US US09/837,297 patent/US7001760B2/en not_active Expired - Fee Related
- 2001-04-20 EP EP01303622A patent/EP1149917B1/de not_active Expired - Lifetime
- 2001-04-20 AT AT01303622T patent/ATE365807T1/de not_active IP Right Cessation
- 2001-04-20 JP JP2001122392A patent/JP3621355B2/ja not_active Expired - Fee Related
- 2001-04-20 DE DE60129069T patent/DE60129069D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US7001760B2 (en) | 2006-02-21 |
ATE365807T1 (de) | 2007-07-15 |
US20010049145A1 (en) | 2001-12-06 |
EP1149917A2 (de) | 2001-10-31 |
EP1149917A3 (de) | 2001-11-14 |
EP1149917B1 (de) | 2007-06-27 |
JP3621355B2 (ja) | 2005-02-16 |
JP2002320480A (ja) | 2002-11-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |