ATE239749T1 - Phosphor-enthaltende dendrimere als transfektionsagente - Google Patents
Phosphor-enthaltende dendrimere als transfektionsagenteInfo
- Publication number
- ATE239749T1 ATE239749T1 AT00985306T AT00985306T ATE239749T1 AT E239749 T1 ATE239749 T1 AT E239749T1 AT 00985306 T AT00985306 T AT 00985306T AT 00985306 T AT00985306 T AT 00985306T AT E239749 T1 ATE239749 T1 AT E239749T1
- Authority
- AT
- Austria
- Prior art keywords
- phosphorus
- containing dendrimers
- transfection agent
- agents
- dendrimers
- Prior art date
Links
- 239000003795 chemical substances by application Substances 0.000 title abstract 3
- 239000000412 dendrimer Substances 0.000 title abstract 2
- 238000001890 transfection Methods 0.000 title 1
- 208000031295 Animal disease Diseases 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 229920000736 dendritic polymer Polymers 0.000 abstract 1
- 238000012637 gene transfection Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2479—Compounds containing the structure P(=X)n-N-acyl, P(=X)n-N-heteroatom, P(=X)n-N-CN (X = O, S, Se; n = 0, 1)
- C07F9/2491—Compounds containing the structure P(=X)n-N-acyl, P(=X)n-N-heteroatom, P(=X)n-N-CN (X = O, S, Se; n = 0, 1) containing the structure P(=X)n-N-N (X = O, S, Se; n = 0, 1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/65812—Cyclic phosphazenes [P=N-]n, n>=3
- C07F9/65815—Cyclic phosphazenes [P=N-]n, n>=3 n = 3
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Luminescent Compositions (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9914864A FR2801592B1 (fr) | 1999-11-25 | 1999-11-25 | Dendrimeres phosphores et leurs applications comme agents de transfection |
PCT/FR2000/003261 WO2001038335A1 (fr) | 1999-11-25 | 2000-11-23 | Dendrimeres phosphores comme agents de transfevtion |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE239749T1 true ATE239749T1 (de) | 2003-05-15 |
Family
ID=9552551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00985306T ATE239749T1 (de) | 1999-11-25 | 2000-11-23 | Phosphor-enthaltende dendrimere als transfektionsagente |
Country Status (9)
Country | Link |
---|---|
US (1) | US6969528B1 (de) |
EP (1) | EP1232165B1 (de) |
JP (1) | JP2003514912A (de) |
AT (1) | ATE239749T1 (de) |
CA (1) | CA2392697A1 (de) |
DE (1) | DE60002603T2 (de) |
ES (1) | ES2194794T3 (de) |
FR (1) | FR2801592B1 (de) |
WO (1) | WO2001038335A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2834988B1 (fr) * | 2002-01-21 | 2005-07-08 | Centre Nat Rech Scient | Utilisation de dendrimeres phosphores comme medicaments |
FR2838737B1 (fr) * | 2002-04-23 | 2006-02-03 | Centre Nat Rech Scient | Supports solides fonctionnalises par des dendrimeres phosphores, leur procede de preparation et applications |
FR2851565B1 (fr) * | 2003-02-26 | 2005-04-01 | Commissariat Energie Atomique | Dendrimeres phosphores, leur procede de preparation et leur utilisation pour l'extraction des actinides et des lanthanides |
FR2873715B1 (fr) | 2004-07-30 | 2006-11-17 | Centre Nat Rech Scient Cnrse | Utilisation de dendrimeres pour stimuler la croissance cellulaire |
FR2876916B1 (fr) * | 2004-10-25 | 2007-01-05 | Midi Pyrenees Incubateur | Produit implantable de surface fonctionnalisee au moyen de dendrimeres a terminaisons anioniques |
FR2896251B1 (fr) * | 2006-01-13 | 2008-04-11 | Univ Rennes 1 Etablissement Pu | Composes fluorescents dendrimeriques et utilisation de tels composes dans le cadre de procedes ou dispositifs multiphotoniques. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2211882T3 (es) * | 1993-07-14 | 2004-07-16 | The Regents Of The University Of California | Sistema de cesion de polinucleotido, automontable que comprende policationes de dendrimeros. |
DE699079T1 (de) * | 1994-03-07 | 1997-09-25 | Dendritech Inc | Bioaktive und/oder gezielte dendrimere-konjugate |
US6440405B1 (en) * | 1999-06-07 | 2002-08-27 | University Of Delaware | Quaternary ammonium functionalized dendrimers and methods of use therefor |
-
1999
- 1999-11-25 FR FR9914864A patent/FR2801592B1/fr not_active Expired - Fee Related
-
2000
- 2000-11-23 US US10/130,739 patent/US6969528B1/en not_active Expired - Fee Related
- 2000-11-23 WO PCT/FR2000/003261 patent/WO2001038335A1/fr active IP Right Grant
- 2000-11-23 EP EP00985306A patent/EP1232165B1/de not_active Expired - Lifetime
- 2000-11-23 ES ES00985306T patent/ES2194794T3/es not_active Expired - Lifetime
- 2000-11-23 DE DE60002603T patent/DE60002603T2/de not_active Expired - Lifetime
- 2000-11-23 AT AT00985306T patent/ATE239749T1/de not_active IP Right Cessation
- 2000-11-23 JP JP2001540098A patent/JP2003514912A/ja active Pending
- 2000-11-23 CA CA002392697A patent/CA2392697A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1232165A1 (de) | 2002-08-21 |
ES2194794T3 (es) | 2003-12-01 |
FR2801592A1 (fr) | 2001-06-01 |
JP2003514912A (ja) | 2003-04-22 |
DE60002603T2 (de) | 2004-02-26 |
EP1232165B1 (de) | 2003-05-07 |
US6969528B1 (en) | 2005-11-29 |
DE60002603D1 (de) | 2003-06-12 |
FR2801592B1 (fr) | 2002-02-22 |
CA2392697A1 (en) | 2001-05-31 |
WO2001038335A1 (fr) | 2001-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE340560T1 (de) | Verfahren und zusammensetzungen für nichtvirale gentherapie zur behandlung von hyperproliferativen krankheiten | |
JP2023011696A (ja) | 核酸産物およびその投与方法 | |
CY1121447T1 (el) | Συνθεσεις για αυξηση δραστηριοτητας τελομερασης | |
BRPI0510206A (pt) | método de identificação de fenótipo, célula isolada, métodos de identificação de agentes, agentes, agentes terapêuticos, método de avaliação de agente terapêutico, composição farmacêutica, métodos de tratamento, prevenção ou melhoria de disfunções e métodos de modulação | |
ATE445417T1 (de) | Ex vivo verfahren und zusammensetzungen zur nukleinsäureverabreichung | |
MX2007006524A (es) | Metodos para el suministro dirigido de material genetico al higado. | |
WO2004011624A3 (en) | Double stranded rna structures and constructs, and methods for generating and using the same | |
WO2004035765A3 (en) | Double-stranded rna structures and constructs, and methods for generating and using the same | |
DE69922933D1 (de) | Anwendungen für humane nicht autologe, mesenchymale stammzellen | |
WO2002020722A3 (en) | Methods and compositions for in vitro targeting | |
WO2005030083A3 (en) | Methods and products which utilize n-acyl-l-aspartic acid | |
WO1999040197A3 (en) | Variants of the angiogenic factor vascular endothelial cell growth factor: vegf | |
BR9914643A (pt) | Vetores adeno-associados para expressão dofator viii por células alvo | |
HK1020756A1 (en) | Use of angiogenic factor vegf145 in treating cardiovascular disease | |
WO1999064576A3 (en) | Human genes differentially expressed in colon cancer | |
DK1526840T3 (da) | Nanopartikler til DNA administration til et målorgan | |
FR2805821B1 (fr) | Sequences d'acides amines facilitant la penetration d'une substance d'interet a l'interieur des cellules et/ou des noyaux cellulaires | |
WO2005120588A3 (en) | Peptides delivered to cell nuclei | |
DK1175489T3 (da) | Oligonukleotider indeholdende en antisense-sekvens stabiliseret af en sekundær struktur og farmaceutiske præparater indeholdende disse oligonukleotider | |
ATE239749T1 (de) | Phosphor-enthaltende dendrimere als transfektionsagente | |
NZ504445A (en) | Nucleic acid sequences of genes of the high mobility group proteins and their use in treating tumours, vascular disorders and as a contraceptive | |
ATE287722T1 (de) | Mittel zur behandlung maligner erkrankungen unter verwendung des proteins yb-1 | |
ATE365807T1 (de) | Hepatitis b virus vektoren für gentherapie | |
EP1277843A3 (de) | Neue humane Gene und Genexpressionsprodukte die in Zusammenhang mit Darmkrebs stehen | |
ATE247978T1 (de) | Verwendung von ompa enterobakterproteinen um zielgerichtet antigen-präsentierende zellen anzusteuern |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |