JP2018021037A5 - - Google Patents

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Publication number
JP2018021037A5
JP2018021037A5 JP2017148823A JP2017148823A JP2018021037A5 JP 2018021037 A5 JP2018021037 A5 JP 2018021037A5 JP 2017148823 A JP2017148823 A JP 2017148823A JP 2017148823 A JP2017148823 A JP 2017148823A JP 2018021037 A5 JP2018021037 A5 JP 2018021037A5
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JP
Japan
Prior art keywords
recombinant fsh
pharmaceutical composition
cell line
sialylation
sialyltransferase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017148823A
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English (en)
Japanese (ja)
Other versions
JP6762916B2 (ja
JP2018021037A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2018021037A publication Critical patent/JP2018021037A/ja
Publication of JP2018021037A5 publication Critical patent/JP2018021037A5/ja
Priority to JP2019194476A priority Critical patent/JP7316905B2/ja
Application granted granted Critical
Publication of JP6762916B2 publication Critical patent/JP6762916B2/ja
Priority to JP2021175403A priority patent/JP2022031652A/ja
Priority to JP2023215339A priority patent/JP2024038000A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017148823A 2008-04-16 2017-08-01 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ Active JP6762916B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2019194476A JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2021175403A JP2022031652A (ja) 2008-04-16 2021-10-27 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2023215339A JP2024038000A (ja) 2008-04-16 2023-12-21 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4542408P 2008-04-16 2008-04-16
US61/045,424 2008-04-16
EP08251528.9 2008-04-25
EP08251528 2008-04-25

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2016198588A Division JP6486310B2 (ja) 2008-04-16 2016-10-07 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019194476A Division JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Publications (3)

Publication Number Publication Date
JP2018021037A JP2018021037A (ja) 2018-02-08
JP2018021037A5 true JP2018021037A5 (enExample) 2018-11-08
JP6762916B2 JP6762916B2 (ja) 2020-09-30

Family

ID=39717519

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2011504527A Pending JP2011519359A (ja) 2008-04-16 2009-04-16 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2014262056A Pending JP2015120696A (ja) 2008-04-16 2014-12-25 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2016198588A Active JP6486310B2 (ja) 2008-04-16 2016-10-07 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2017148823A Active JP6762916B2 (ja) 2008-04-16 2017-08-01 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2019194476A Active JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2021175403A Pending JP2022031652A (ja) 2008-04-16 2021-10-27 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2023215339A Pending JP2024038000A (ja) 2008-04-16 2023-12-21 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2011504527A Pending JP2011519359A (ja) 2008-04-16 2009-04-16 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2014262056A Pending JP2015120696A (ja) 2008-04-16 2014-12-25 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2016198588A Active JP6486310B2 (ja) 2008-04-16 2016-10-07 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019194476A Active JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2021175403A Pending JP2022031652A (ja) 2008-04-16 2021-10-27 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2023215339A Pending JP2024038000A (ja) 2008-04-16 2023-12-21 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Country Status (29)

Country Link
US (6) US8951967B2 (enExample)
EP (7) EP3144318B1 (enExample)
JP (7) JP2011519359A (enExample)
KR (5) KR20170110741A (enExample)
CN (3) CN102066414A (enExample)
AR (1) AR071479A1 (enExample)
AU (5) AU2009237479B2 (enExample)
BR (1) BRPI0910461B8 (enExample)
CA (1) CA2725257A1 (enExample)
CY (1) CY1115413T1 (enExample)
DK (6) DK3045471T3 (enExample)
ES (5) ES2629392T3 (enExample)
FI (4) FI4015527T3 (enExample)
FR (3) FR17C1020I2 (enExample)
HR (5) HRP20250313T1 (enExample)
HU (9) HUE071059T2 (enExample)
IL (2) IL208538A (enExample)
LT (8) LT3045471T (enExample)
MX (3) MX2010011343A (enExample)
NO (4) NO2017025I1 (enExample)
NZ (1) NZ588381A (enExample)
PL (6) PL3144318T3 (enExample)
PT (6) PT3098234T (enExample)
RU (3) RU2682270C2 (enExample)
SA (1) SA109300228B1 (enExample)
SI (6) SI2268666T1 (enExample)
TW (1) TWI488640B (enExample)
WO (1) WO2009127826A1 (enExample)
ZA (1) ZA201007373B (enExample)

Families Citing this family (29)

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TWI488640B (zh) 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI604850B (zh) * 2009-10-05 2017-11-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
HUE025514T2 (en) 2010-09-29 2016-02-29 Ferring Bv Preparation for use in treating infertility
KR101898302B1 (ko) 2010-10-15 2018-09-13 제이씨알 파마 가부시키가이샤 당사슬의 비환원 말단이 만노오스 잔기인 당 단백질의 제조 방법
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
AR090095A1 (es) 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
WO2013093760A2 (en) * 2011-12-19 2013-06-27 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
JP6279466B2 (ja) * 2012-04-27 2018-02-14 Ｊｃｒファーマ株式会社 新規な発現ベクター
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
JP6652334B2 (ja) * 2014-05-31 2020-02-19 Ｊｃｒファーマ株式会社 ウリジンとｎ−アセチル−ｄ−マンノサミンとを含有する培地
JP2018500934A (ja) * 2014-12-22 2018-01-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｍｐ依存性シアリダーゼ活性
ES2879838T3 (es) 2015-04-17 2021-11-23 Ferring Bv Composición que comprende FSH para el tratamiento de la esterilidad
CN107709350A (zh) * 2015-06-26 2018-02-16 辉凌公司 纯化和/或病毒灭活的方法
EP3205719A1 (en) * 2016-02-15 2017-08-16 CEVEC Pharmaceuticals GmbH Cell lines for producing recombinant glycoproteins with di-antennary n-glycans, methods using the same, and recombinant glycoproteins
GB201603280D0 (en) 2016-02-24 2016-04-13 Ferring Bv Stable liquid gonadotropin formulation
EP3382014A1 (en) * 2017-03-29 2018-10-03 CEVEC Pharmaceuticals GmbH Recombinant glycoproteins with reduced antennary fucosylation
EP3441471A1 (en) 2017-08-08 2019-02-13 CEVEC Pharmaceuticals GmbH Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines
ES2989511T3 (es) 2017-09-01 2024-11-26 Ferring Bv Composición para la estimulación ovárica controlada
EP4534145A3 (en) 2018-04-30 2025-07-02 Ferring B.V. Composition for controlled ovarian stimulation
TWI846743B (zh) 2018-10-17 2024-07-01 荷蘭商菲林公司 用於控制性卵巢刺激之組成物及方法
US20220380785A1 (en) * 2019-11-01 2022-12-01 The University Of British Columbia Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh) 2020-12-09 2022-10-01 荷蘭商菲林公司 用於受控的卵巢刺激之組成物及方法
EP4504236A1 (en) 2022-04-01 2025-02-12 Ferring B.V. Mixed protocol for treatment of infertility
JP2025516966A (ja) 2022-05-26 2025-05-30 フェリング ベスローテン フェンノートシャップ 男性の不妊症の治療のための組成物及び方法
EP4551244A1 (en) 2022-07-08 2025-05-14 Ferring B.V. Compositions and methods for intrauterine insemination (iui)
TW202504578A (zh) 2023-07-20 2025-02-01 荷蘭商輝凌責任有限公司 緩釋載藥微粒

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US5541083A (en) 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
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TW518235B (en) * 1997-01-15 2003-01-21 Akzo Nobel Nv A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage
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JPH1111665A (ja) 1997-06-28 1999-01-19 Shibuya Kogyo Co Ltd 無菌エア搬送コンベヤ装置
TWI235158B (en) * 1997-09-01 2005-07-01 Kirin Brewery Human thrombopoietin produced by human established cell lines, processes foe preparing the same, and pharmaceutical composition comprising the same
WO2000067778A1 (en) 1999-05-07 2000-11-16 Applied Research Systems Ars Holding N.V. Gonadotrophins
JP2002011665A (ja) 2000-06-28 2002-01-15 Sintokogio Ltd ショットブラスト装置モニタシステム
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TWI488640B (zh) 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI604850B (zh) 2009-10-05 2017-11-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
WO2012016575A1 (en) 2010-08-03 2012-02-09 King Saud University Stoma coat
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
HUE025514T2 (en) 2010-09-29 2016-02-29 Ferring Bv Preparation for use in treating infertility
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
AR090095A1 (es) 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
EP3131571A1 (en) 2014-04-18 2017-02-22 Glycotope GmbH Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone

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