|
US3709898A
(en)
|
1971-02-09 |
1973-01-09 |
Upjohn Co |
Process for the production of triazolobenzodiazepines and intermediates
|
|
US3681343A
(en)
|
1971-05-11 |
1972-08-01 |
Upjohn Co |
6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines
|
|
US3812259A
(en)
|
1971-08-09 |
1974-05-21 |
Upjohn Co |
Animal feed and process
|
|
CH622019A5
(en)
|
1975-10-23 |
1981-03-13 |
Upjohn Co |
Process for the preparation of aminotriazolobenzodiazepines
|
|
FR2329668A1
(fr)
|
1975-10-27 |
1977-05-27 |
Upjohn Co |
Procede de preparation d'aminotriazolobenzodiazepines
|
|
EP0087850A1
(en)
|
1982-01-04 |
1983-09-07 |
The Upjohn Company |
Benzodiazepines for anti-hypertensive use
|
|
DE3435973A1
(de)
|
1984-10-01 |
1986-04-10 |
Boehringer Ingelheim KG, 6507 Ingelheim |
Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
|
|
DE3724164A1
(de)
|
1986-07-25 |
1988-01-28 |
Boehringer Ingelheim Kg |
Neue 1,4-benzodiazepine, ihre herstellung und verwendung
|
|
DE3878833T2
(de)
|
1987-05-28 |
1993-06-09 |
Yoshitomi Pharmaceutical |
Thieno(triazolo)diazepinverbindungen, und medizinische verwendung derselben.
|
|
JPH0676326B2
(ja)
|
1988-05-24 |
1994-09-28 |
吉富製薬株式会社 |
循環器系疾患治療薬
|
|
EP0368175A1
(de)
|
1988-11-06 |
1990-05-16 |
Boehringer Ingelheim Kg |
3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin.
|
|
EP0387613A1
(de)
|
1989-03-03 |
1990-09-19 |
Boehringer Ingelheim Kg |
Neue Thienodiazepine
|
|
EP0407955A1
(de)
|
1989-07-12 |
1991-01-16 |
Boehringer Ingelheim Kg |
Neue Hetrazepine mit PAF-antagonistischer Wirkung, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
DE4010528A1
(de)
|
1990-04-02 |
1991-10-17 |
Boehringer Ingelheim Kg |
Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
|
|
CA2120939A1
(en)
|
1991-10-11 |
1993-04-15 |
Tetsuya Tahara |
Therapeutic agent for osteoporosis and diazepine compound
|
|
WO1994006802A1
(fr)
|
1992-09-18 |
1994-03-31 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Compose de thienodiazepine et son utilisation medicinale
|
|
EP0692483A1
(en)
|
1993-03-30 |
1996-01-17 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Cell adhesion inhibitor and thienotriazolodiazepine compound
|
|
JP3001979U
(ja)
|
1994-03-14 |
1994-09-06 |
有限会社マルセ木工 |
竿掛け具
|
|
WO1995032963A1
(en)
|
1994-06-01 |
1995-12-07 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Thienylazole compound and thienotriazolodiazepine compound
|
|
EP0801651B1
(de)
|
1995-01-06 |
2001-07-11 |
F. Hoffmann-La Roche Ag |
Hydroxymethyl-imidazodiazepine und deren ester
|
|
JPH11512107A
(ja)
|
1995-09-09 |
1999-10-19 |
エフ・ホフマン−ラ ロシュ アーゲー |
チエノトリアゾロジアゼピンのアポリポタンパク質a−iレベル増加のための用途
|
|
CN1227555A
(zh)
|
1996-06-12 |
1999-09-01 |
日本烟草产业株式会社 |
细胞因子生成抑制剂、三氮䓬化合物及其中间体
|
|
US5693641A
(en)
|
1996-08-16 |
1997-12-02 |
Berlex Laboratories Inc. |
Bicyclic pyrimidine derivatives and their use as anti-coagulants
|
|
KR100338144B1
(ko)
|
1996-09-13 |
2002-05-24 |
가마쿠라 아키오 |
티에노트리아졸로디아제핀 화합물 및 그의 약제학적 용도
|
|
US6444664B1
(en)
|
1997-04-18 |
2002-09-03 |
Nederlandse Organisatie Voor Toegepast - Natuurweten Schappelijk Onderzoek (Tno) |
Method for controlling the plasma level of lipoproteins to treat alzheimeris disease
|
|
JPH11228576A
(ja)
|
1997-12-10 |
1999-08-24 |
Japan Tobacco Inc |
アポトーシス抑制剤
|
|
FR2779652B1
(fr)
|
1998-06-15 |
2001-06-08 |
Sod Conseils Rech Applic |
Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
|
|
US7589167B2
(en)
|
2000-02-22 |
2009-09-15 |
J. David Gladstone Institutes |
ZA loops of bromodomains
|
|
JP4875277B2
(ja)
|
2000-06-16 |
2012-02-15 |
田辺三菱製薬株式会社 |
放出pH域及び/又は速度制御組成物
|
|
WO2002002557A2
(en)
|
2000-06-30 |
2002-01-10 |
Neurogen Corporation |
2-phenylimidazo[1,2-a]pyridine derivatives: a new class of gaba brain receptor ligands
|
|
US20060142257A1
(en)
|
2001-01-19 |
2006-06-29 |
Eberhard Nieschlag |
Male contraceptive formulation comprising norethisterone
|
|
US6979682B2
(en)
|
2001-02-23 |
2005-12-27 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Platelet-activating factor antagonist inhibition of angiogenesis and tumor growth induced by basic fibroblast
|
|
EA007062B1
(ru)
|
2001-09-04 |
2006-06-30 |
Бёрингер Ингельхайм Фарма Гмбх Унд Ко. Кг |
Новые дигидроптеридиноны, способы их получения и их применение в качестве лекарственных средств
|
|
US6806272B2
(en)
|
2001-09-04 |
2004-10-19 |
Boehringer Ingelheim Pharma Kg |
Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
|
|
US20030216758A1
(en)
|
2001-12-28 |
2003-11-20 |
Angiotech Pharmaceuticals, Inc. |
Coated surgical patches
|
|
GB0206215D0
(en)
*
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
|
JP3096299U
(ja)
|
2003-02-20 |
2003-09-12 |
宇輪工業股▲ふん▼有限公司 |
足踏み式健康器
|
|
US6861422B2
(en)
|
2003-02-26 |
2005-03-01 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
|
|
GB0305929D0
(en)
*
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
|
WO2005002526A2
(en)
|
2003-07-01 |
2005-01-13 |
President And Fellows Of Harvard College |
Method and compositions for treatment of viral infections
|
|
US20070105839A1
(en)
|
2003-09-18 |
2007-05-10 |
Patricia Imbach |
2, 4-Di (phenylamino) pyrimidines useful in the treatment of proliferative disorders
|
|
EP1528056A1
(en)
|
2003-10-29 |
2005-05-04 |
Academisch Ziekenhuis bij de Universiteit van Amsterdam |
Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors
|
|
US20060074088A1
(en)
|
2004-08-14 |
2006-04-06 |
Boehringer Ingelheim International Gmbh |
Dihydropteridinones for the treatment of cancer diseases
|
|
US7728134B2
(en)
|
2004-08-14 |
2010-06-01 |
Boehringer Ingelheim International Gmbh |
Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
|
|
US7759485B2
(en)
|
2004-08-14 |
2010-07-20 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of dihydropteridinones
|
|
US20060035903A1
(en)
|
2004-08-14 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Storage stable perfusion solution for dihydropteridinones
|
|
US20060058311A1
(en)
|
2004-08-14 |
2006-03-16 |
Boehringer Ingelheim International Gmbh |
Combinations for the treatment of diseases involving cell proliferation
|
|
GB0419161D0
(en)
*
|
2004-08-27 |
2004-09-29 |
Novartis Ag |
Organic compounds
|
|
JP2008510771A
(ja)
|
2004-08-27 |
2008-04-10 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ジヒドロプテリジノン、その製造方法および医薬薬剤としてのその使用
|
|
CN1759834B
(zh)
|
2004-09-17 |
2010-06-23 |
中国医学科学院医药生物技术研究所 |
黄连素或其与辛伐他汀联合在制备用于预防或治疗与血脂有关疾病或症状的产品中用途
|
|
US8044042B2
(en)
|
2005-05-30 |
2011-10-25 |
Mitsubishi Tanabe Pharma Corporation |
Thienotriazolodiazepine compound and medicinal use thereof
|
|
EP1904457B1
(en)
|
2005-06-08 |
2017-09-06 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
CA2617589A1
(en)
|
2005-08-03 |
2007-02-08 |
Boehringer Ingelheim International Gmbh |
Dihydropteridinones in the treatment of respiratory diseases
|
|
US8133900B2
(en)
|
2005-11-01 |
2012-03-13 |
Targegen, Inc. |
Use of bi-aryl meta-pyrimidine inhibitors of kinases
|
|
KR101467723B1
(ko)
|
2005-11-01 |
2014-12-03 |
탈자진 인코포레이티드 |
키나제의 비-아릴 메타-피리미딘 억제제
|
|
US8604042B2
(en)
*
|
2005-11-01 |
2013-12-10 |
Targegen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
JP5140600B2
(ja)
|
2005-12-23 |
2013-02-06 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
オーロラキナーゼのアザインドール阻害薬
|
|
AU2007207053B2
(en)
|
2006-01-17 |
2012-05-24 |
F. Hoffmann-La Roche Ag |
Aryl-isoxazol-4-yl-imidazo[1,2-a]pyridine useful for the treatment of Alzheimer's disease via GABA receptors
|
|
CN101420955B
(zh)
|
2006-02-14 |
2013-07-17 |
沃泰克斯药物股份有限公司 |
可用作蛋白激酶抑制剂的二氢二氮杂*
|
|
CA2652648C
(en)
|
2006-02-14 |
2016-10-25 |
Vertex Pharmaceuticals Incorporated |
Dihydrodiazepines useful as inhibitors of protein kinases
|
|
US20070218135A1
(en)
|
2006-03-14 |
2007-09-20 |
Glenmark Pharmaceuticals Limited |
Sustained release matrix pharmaceutical composition
|
|
AU2007248112A1
(en)
|
2006-05-03 |
2007-11-15 |
Novartis Ag |
Use of organic compounds
|
|
US20090312336A1
(en)
|
2006-05-19 |
2009-12-17 |
Astrazeneca Ab |
Dihydropteridine compounds as anti proliferative agents
|
|
WO2008009909A1
(en)
|
2006-07-17 |
2008-01-24 |
Astrazeneca Ab |
Pteridimones as modulators of polo-like kinase
|
|
MX337906B
(es)
|
2006-10-19 |
2016-03-28 |
Signal Pharm Llc |
Compuestos de heteroarilo, composiciones de los mismos, y su uso como inhibidores de proteina cinasas.
|
|
BRPI0718120A2
(pt)
|
2006-10-25 |
2013-11-12 |
Chroma Therapeutics Ltd |
Derivados de pteridina como inibidores de cinase do tipo pólo úteis no tratamento de câncer
|
|
WO2008066887A2
(en)
|
2006-11-30 |
2008-06-05 |
Albert Einstein College Of Medicine Of Yeshiva University |
Small molecule inhibitors of bcl6
|
|
EP2114873B1
(en)
|
2006-12-26 |
2013-02-20 |
Lantheus Medical Imaging, Inc. |
N-[3-bromo-4-(3- [18f]fluoropropoxy)-benzyl]-guanidine for imaging cardiac innervation
|
|
JP2008156311A
(ja)
|
2006-12-26 |
2008-07-10 |
Institute Of Physical & Chemical Research |
Brd2ブロモドメイン結合剤
|
|
WO2008113711A1
(en)
|
2007-03-22 |
2008-09-25 |
F. Hoffmann-La Roche Ag |
Substituted pyrimidodiazepines useful as plk1 inhibitors
|
|
WO2008137081A1
(en)
|
2007-05-02 |
2008-11-13 |
The Trustees Of Columbia University In The City Of New York |
Substituted ( 5, 6 ) -dihydronaphraalenyl compounds as reversible male contraceptives
|
|
KR20080107050A
(ko)
|
2007-06-05 |
2008-12-10 |
울산대학교 산학협력단 |
항-cd137 단일클론 항체를 포함하는 만성이식편대숙주 질환의 예방 또는 치료용 약학적 조성물
|
|
NZ583061A
(en)
|
2007-08-15 |
2012-06-29 |
Vertex Pharma |
4-(9-(3,3-difluorocyclopentyl)-5,7,7-trimethyl-6-oxo-6,7,8,9-tetrahydro-5h-pyrimido[4,5-b[1,4]diazepin-2-ylamino)-3-methoxybenzamide derivatives as inhibitors of the human protein kinases plk1 to plk4 for the treatment of proliferative diseases
|
|
NZ584760A
(en)
|
2007-09-25 |
2012-03-30 |
Takeda Pharmaceutical |
Polo-like kinase inhibitors
|
|
WO2009040556A1
(en)
|
2007-09-28 |
2009-04-02 |
Cyclacel Limited |
Pyrimidine derivatives as protein kinase inhibitors
|
|
WO2009067547A1
(en)
|
2007-11-19 |
2009-05-28 |
Takeda Pharmaceutical Company Limited |
Polo-like kinase inhibitors
|
|
US20110028405A1
(en)
|
2007-12-20 |
2011-02-03 |
Richard John Harrison |
Sulfamides as zap-70 inhibitors
|
|
US8476260B2
(en)
|
2007-12-28 |
2013-07-02 |
Mitsubishi Tanabe Pharma Corporation |
Antitumor agent
|
|
CA2717529A1
(en)
|
2008-03-11 |
2009-09-17 |
Cellzome Limited |
Sulfonamides as zap-70 inhibitors
|
|
EP2112152A1
(en)
|
2008-04-22 |
2009-10-28 |
GPC Biotech AG |
Dihydropteridinones as Plk Inhibitors
|
|
JP2011527667A
(ja)
|
2008-06-18 |
2011-11-04 |
武田薬品工業株式会社 |
ハロ置換ピリミドジアゼピン
|
|
WO2010015340A1
(en)
|
2008-08-06 |
2010-02-11 |
Bayer Schering Pharma Aktiengesellschaft |
Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment
|
|
AU2009309691B2
(en)
|
2008-10-30 |
2015-04-02 |
Circomed Llc |
Thienotriazolodiazepine derivatives active on apo A
|
|
PT2356123E
(pt)
|
2008-11-13 |
2012-10-31 |
Hoffmann La Roche |
Espiro-5,6-di-hidro-4h-2,3,5,10b-tetra-azabenzo[ e]azulenos
|
|
WO2010080712A2
(en)
|
2009-01-06 |
2010-07-15 |
Dana Farber Cancer Institute |
Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders
|
|
SG172958A1
(en)
|
2009-01-23 |
2011-08-29 |
Takeda Pharmaceutical |
Poly (adp-ribose) polymerase (parp) inhibitors
|
|
CN102020643A
(zh)
|
2009-09-22 |
2011-04-20 |
上海恒瑞医药有限公司 |
二氢喋啶酮类衍生物、其制备方法及其在医药上的应用
|
|
RU2012116525A
(ru)
|
2009-09-25 |
2013-10-27 |
Вертекс Фармасьютикалз Инкорпорейтед |
Способы получения перемидиновых производных, пригодных в качестве ингибиторов протеинкиназ
|
|
GB0919431D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919426D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
US9102677B2
(en)
|
2009-11-05 |
2015-08-11 |
Glaxosmithkline Llc |
Benzodiazepine bromodomain inhibitor
|
|
MX2012005295A
(es)
|
2009-11-05 |
2012-06-19 |
Glaxosmithkline Llc |
Inhibidor de bromodominio de benzodiazepina.
|
|
GB0919423D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919432D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Use
|
|
GB0919434D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
US20120329803A1
(en)
|
2010-02-17 |
2012-12-27 |
Boehringer Ingelheim International Gmbh |
Dihydropteridinones, method for production and use thereof
|
|
MX362384B
(es)
|
2010-05-14 |
2019-01-15 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para tratar neoplasias, enfermedades inflamatorias y otros trastornos.
|
|
CA2799373A1
(en)
|
2010-05-14 |
2011-11-17 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for modulating metabolism
|
|
MX354217B
(es)
|
2010-05-14 |
2018-02-19 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para el tratamiento de leucemia.
|
|
CA2799381A1
(en)
|
2010-05-14 |
2011-11-17 |
Dana-Farber Cancer Institute, Inc. |
Male contraceptive compositions and methods of use
|
|
US9085582B2
(en)
|
2010-06-22 |
2015-07-21 |
Glaxosmithkline Llc |
Benzotriazolodiazepine compounds inhibitors of bromodomains
|
|
US20120014979A1
(en)
|
2010-07-16 |
2012-01-19 |
Alexander Dent |
Use of bcl6 inhibitors for treating autoimmune diseases
|
|
US9358233B2
(en)
|
2010-11-29 |
2016-06-07 |
Boehringer Ingelheim International Gmbh |
Method for treating acute myeloid leukemia
|
|
AR084070A1
(es)
|
2010-12-02 |
2013-04-17 |
Constellation Pharmaceuticals Inc |
Inhibidores del bromodominio y usos de los mismos
|
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
|
CA2828212A1
(en)
|
2011-02-23 |
2012-08-30 |
Shiraz Mujtaba |
Inhibitors of bromodomains as modulators of gene expression
|
|
EP2681216B1
(en)
|
2011-02-28 |
2017-09-27 |
Epizyme, Inc. |
Substituted 6,5-fused bicyclic heteroaryl compounds
|
|
JP2014513925A
(ja)
*
|
2011-03-07 |
2014-06-19 |
フォンダッツィオーネ・テレソン |
Tfeb変異体およびその使用
|
|
WO2013033270A2
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution, and methods of using same
|
|
WO2013033269A1
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bioorthogonal monomers capable of dimerizing and targeting bromodomains and methods of using same
|
|
DE102011082013A1
(de)
|
2011-09-01 |
2013-03-07 |
Bayer Pharma AG |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
|
|
WO2013097052A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
|
CN104203267A
(zh)
|
2012-02-17 |
2014-12-10 |
安迅生物制药公司 |
用于治疗流感和副流感患者的方法、化合物和组合物
|
|
WO2013148197A1
(en)
|
2012-03-28 |
2013-10-03 |
The J. David Gladstone Institutes |
Compositions and methods for reactivating latent immunodeficiency virus
|
|
RU2635856C2
(ru)
|
2012-08-08 |
2017-11-16 |
Новоматик Аг |
Способ и система для отслеживания игровой активности
|
|
EP2900221B1
(en)
|
2012-09-28 |
2019-03-06 |
Oncoethix GmbH |
Pharmaceutical formulation containing thienotriazolodiazepine compounds
|
|
US9567301B2
(en)
|
2012-11-02 |
2017-02-14 |
Dana-Farber Cancer Institute, Inc. |
Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors
|
|
CN105229002A
(zh)
|
2012-12-20 |
2016-01-06 |
拜耳医药股份有限公司 |
抑制bet蛋白的二氢吡啶并吡嗪酮
|
|
US20140254659A1
(en)
|
2013-03-11 |
2014-09-11 |
Mediatek Inc. |
Video coding method using at least evaluated visual quality and related video coding apparatus
|
|
BR112015022674A2
(pt)
|
2013-03-11 |
2017-07-18 |
Abbvie Inc |
inibidores de bromodomínio
|
|
US10035800B2
(en)
|
2013-03-12 |
2018-07-31 |
Abbvie Inc. |
Substituted 1,4,10-triazadibenzo[cd,f]azulenes, substituted 1,4,5,10-tetraazadibenzo[cd,f]azulenes and substituted 1,4,5,7,10-pentaazadibenzo[cd,f]azulenes as bromodomain inhibitors
|
|
WO2014159392A1
(en)
|
2013-03-14 |
2014-10-02 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
|
KR20160034379A
(ko)
|
2013-07-25 |
2016-03-29 |
다나-파버 캔서 인스티튜트 인크. |
전사 인자의 억제제 및 그의 용도
|
|
JP6663852B2
(ja)
|
2013-09-19 |
2020-03-13 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
Bh3プロファイリングの方法
|
|
WO2015081280A1
(en)
|
2013-11-26 |
2015-06-04 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution
|
|
WO2015081284A1
(en)
|
2013-11-26 |
2015-06-04 |
Coferon, Inc. |
Bivalent bromodomain ligands, and methods of using same
|
|
EP3080132A4
(en)
|
2013-12-10 |
2017-08-02 |
AbbVie Inc. |
Bromodomain inhibitors
|
|
RU2016134947A
(ru)
|
2014-01-31 |
2018-03-01 |
Дана-Фарбер Кансер Институт, Инк. |
Производные диаминопиримидин бензолсульфона и их применение
|
|
KR20160111520A
(ko)
|
2014-01-31 |
2016-09-26 |
다나-파버 캔서 인스티튜트 인크. |
디히드로프테리디논 유도체 및 그의 용도
|
|
EP3099696A4
(en)
|
2014-01-31 |
2017-07-05 |
Dana-Farber Cancer Institute, Inc. |
Diazepane derivatives and uses thereof
|
|
WO2015117087A1
(en)
|
2014-01-31 |
2015-08-06 |
Dana-Farber Cancer Institute, Inc. |
Uses of diazepane derivatives
|
|
US20170008888A1
(en)
|
2014-02-26 |
2017-01-12 |
Kyorin Pharmaceutical Co., Ltd. |
Heterocyclic compounds
|
|
AU2015222805B2
(en)
|
2014-02-28 |
2020-05-21 |
Tensha Therapeutics, Inc. |
Treatment of conditions associated with hyperinsulinaemia
|
|
US20180228907A1
(en)
|
2014-04-14 |
2018-08-16 |
Arvinas, Inc. |
Cereblon ligands and bifunctional compounds comprising the same
|
|
BR112017002190A2
(pt)
|
2014-08-08 |
2017-11-21 |
Dana Farber Cancer Inst Inc |
derivados de di-hidropteridinona e usos dos mesmos
|
|
EP3177626A4
(en)
|
2014-08-08 |
2017-12-27 |
Dana Farber Cancer Institute, Inc. |
Diazepane derivatives and uses thereof
|
|
CN107223057A
(zh)
|
2014-12-05 |
2017-09-29 |
H·李·莫菲特癌症中心研究所公司 |
布罗莫结构域抑制剂作为癌症免疫治疗的补充剂
|
|
US9694084B2
(en)
|
2014-12-23 |
2017-07-04 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce targeted protein degradation through bifunctional molecules
|
|
JP6815318B2
(ja)
|
2014-12-23 |
2021-01-20 |
ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド |
二官能性分子によって標的化タンパク質分解を誘導する方法
|
|
HK1249058A1
(zh)
|
2015-03-18 |
2018-10-26 |
Arvinas, Inc. |
用於增强靶向蛋白质降解的化合物和方法
|
|
AU2016276963C1
(en)
|
2015-06-12 |
2021-08-05 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
|
WO2017007612A1
(en)
|
2015-07-07 |
2017-01-12 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce targeted protein degradation through bifunctional molecules
|
|
CA2994969A1
(en)
|
2015-08-06 |
2017-02-09 |
Dana-Farber Cancer Institute, Inc. |
Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses
|
|
EP3337476A4
(en)
|
2015-08-19 |
2019-09-04 |
Arvinas, Inc. |
Compounds and methods for the targeted degradation of bromodomain-containing proteins
|
|
CA2992889A1
(en)
|
2015-09-04 |
2017-03-09 |
F. Hoffmann-La Roche Ag |
Phenoxymethyl derivatives
|
|
PT3347356T
(pt)
|
2015-09-09 |
2021-06-28 |
Jubilant Biosys Ltd |
Derivados tricíclicos de piridinaa-2-ona fundidos e a sua utilização como inibidores brd4
|
|
US10881668B2
(en)
|
2015-09-11 |
2021-01-05 |
Dana-Farber Cancer Institute, Inc. |
Acetamide thienotriazolodiazepines and uses thereof
|
|
JP6868011B2
(ja)
|
2015-09-11 |
2021-05-12 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ピラゾリル置換ヘテロアリール及び医薬としてのその使用
|
|
CN108472300A
(zh)
|
2015-09-11 |
2018-08-31 |
达纳-法伯癌症研究所股份有限公司 |
氰基噻吩并三唑并二氮杂环庚三烯及其用途
|
|
FI3888658T3
(fi)
|
2015-11-25 |
2024-03-22 |
Effector Therapeutics Inc |
eIF4A:ta inhiboivia yhdisteitä ja niihin liittyviä menetelmiä
|
|
BR112018009212B1
(pt)
|
2015-11-25 |
2022-06-14 |
Gilead Apollo, Llc |
Método para controlar patógenos fúngicos agrícolas
|
|
US20170166583A1
(en)
|
2015-11-25 |
2017-06-15 |
Gilead Apollo, Llc |
Ester acc inhibitors and uses thereof
|
|
SI3380522T1
(sl)
|
2015-11-25 |
2024-02-29 |
Visterra, Inc. |
Molekule protitelesa proti APRIL in uporabe le-teh
|
|
WO2017091617A1
(en)
|
2015-11-25 |
2017-06-01 |
Gilead Apollo, Llc |
Triazole acc inhibitors and uses thereof
|
|
MX2018006499A
(es)
|
2015-11-25 |
2018-08-01 |
Dana Farber Cancer Inst Inc |
Inhibidores de bromodominio bivalentes y usos de los mismos.
|
|
EP3380480B1
(en)
|
2015-11-25 |
2022-12-14 |
Gilead Apollo, LLC |
Pyrazole acc inhibitors and uses thereof
|
|
KR102070746B1
(ko)
|
2015-12-01 |
2020-01-29 |
니혼노야쿠가부시키가이샤 |
3h-피롤로피리딘 화합물 또는 그의 n-옥사이드, 또는 그들의 염류 및 상기 화합물을 함유하는 농원예용 살충제 및 그의 사용 방법
|
|
WO2017197046A1
(en)
|
2016-05-10 |
2017-11-16 |
C4 Therapeutics, Inc. |
C3-carbon linked glutarimide degronimers for target protein degradation
|
|
CN109790143A
(zh)
|
2016-05-10 |
2019-05-21 |
C4医药公司 |
用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体
|
|
WO2017201069A1
(en)
|
2016-05-18 |
2017-11-23 |
Biotheryx, Inc. |
Oxoindoline derivatives as protein function modulators
|
|
GB201608797D0
(en)
|
2016-05-19 |
2016-07-06 |
Ucb Biopharma Sprl |
Therapeutic use
|