JP2016501535A5 - - Google Patents

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Publication number
JP2016501535A5
JP2016501535A5 JP2015548014A JP2015548014A JP2016501535A5 JP 2016501535 A5 JP2016501535 A5 JP 2016501535A5 JP 2015548014 A JP2015548014 A JP 2015548014A JP 2015548014 A JP2015548014 A JP 2015548014A JP 2016501535 A5 JP2016501535 A5 JP 2016501535A5
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JP
Japan
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acid sequence
nucleic acid
composition
recombinant nucleic
subject
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JP2015548014A
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English (en)
Japanese (ja)
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JP6898060B2 (ja
JP2016501535A (ja
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Priority claimed from PCT/US2013/075137 external-priority patent/WO2014093894A2/en
Publication of JP2016501535A publication Critical patent/JP2016501535A/ja
Publication of JP2016501535A5 publication Critical patent/JP2016501535A5/ja
Application granted granted Critical
Publication of JP6898060B2 publication Critical patent/JP6898060B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015548014A 2012-12-13 2013-12-13 Ｄｎａ抗体構築物およびその使用方法 Expired - Fee Related JP6898060B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261737094P 2012-12-13 2012-12-13
US61/737,094 2012-12-13
US201361881376P 2013-09-23 2013-09-23
US61/881,376 2013-09-23
US201361896646P 2013-10-28 2013-10-28
US61/896,646 2013-10-28
PCT/US2013/075137 WO2014093894A2 (en) 2012-12-13 2013-12-13 Dna antibody constructs and method of using same

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2019061531A Division JP2019115355A (ja) 2012-12-13 2019-03-27 Ｄｎａ抗体構築物およびその使用方法
JP2021016537A Division JP2021087433A (ja) 2012-12-13 2021-02-04 Ｄｎａ抗体構築物およびその使用方法

Publications (3)

Publication Number Publication Date
JP2016501535A JP2016501535A (ja) 2016-01-21
JP2016501535A5 true JP2016501535A5 (enExample) 2017-02-02
JP6898060B2 JP6898060B2 (ja) 2021-07-07

Family

ID=50935092

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2015548014A Expired - Fee Related JP6898060B2 (ja) 2012-12-13 2013-12-13 Ｄｎａ抗体構築物およびその使用方法
JP2019061531A Pending JP2019115355A (ja) 2012-12-13 2019-03-27 Ｄｎａ抗体構築物およびその使用方法
JP2020035240A Pending JP2020108381A (ja) 2012-12-13 2020-03-02 Ｄｎａ抗体構築物及びその使用方法
JP2021016537A Withdrawn JP2021087433A (ja) 2012-12-13 2021-02-04 Ｄｎａ抗体構築物およびその使用方法
JP2023040876A Pending JP2023080085A (ja) 2012-12-13 2023-03-15 Ｄｎａ抗体構築物およびその使用方法
JP2023108341A Pending JP2023138998A (ja) 2012-12-13 2023-06-30 Ｄｎａ抗体構築物及びその使用方法

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2019061531A Pending JP2019115355A (ja) 2012-12-13 2019-03-27 Ｄｎａ抗体構築物およびその使用方法
JP2020035240A Pending JP2020108381A (ja) 2012-12-13 2020-03-02 Ｄｎａ抗体構築物及びその使用方法
JP2021016537A Withdrawn JP2021087433A (ja) 2012-12-13 2021-02-04 Ｄｎａ抗体構築物およびその使用方法
JP2023040876A Pending JP2023080085A (ja) 2012-12-13 2023-03-15 Ｄｎａ抗体構築物およびその使用方法
JP2023108341A Pending JP2023138998A (ja) 2012-12-13 2023-06-30 Ｄｎａ抗体構築物及びその使用方法

Country Status (15)

Country Link
US (4) US9994629B2 (enExample)
EP (1) EP2931318A4 (enExample)
JP (6) JP6898060B2 (enExample)
KR (4) KR20210088741A (enExample)
CN (1) CN104853782A (enExample)
AU (7) AU2013358944B2 (enExample)
BR (2) BR112015013700A8 (enExample)
CA (1) CA2889723A1 (enExample)
EA (1) EA201591131A1 (enExample)
HK (1) HK1213481A1 (enExample)
MX (4) MX2015007575A (enExample)
MY (1) MY175708A (enExample)
SG (1) SG10202002718RA (enExample)
WO (1) WO2014093894A2 (enExample)
ZA (1) ZA201503583B (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2931318A4 (en) 2012-12-13 2016-07-20 Univ Pennsylvania DNA ANTIBODY CONSTRUCTS AND METHODS FOR USE THEREOF
SG11201604719WA (en) * 2013-12-13 2016-07-28 Univ Pennsylvania Dna antibody constructs and method of using same
KR102586707B1 (ko) * 2014-10-01 2023-10-11 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 항원 및 어쥬번트로서 인터류킨-21을 갖는 백신
WO2016089862A1 (en) * 2014-12-01 2016-06-09 The Trustees Of The University Of Pennsylvania Dna antibody constructs and method of using same
ES2894304T3 (es) 2015-10-25 2022-02-14 Sanofi Sa Proteínas de unión triespecíficas y/o trivalentes para la prevención o tratamiento de infección por VIH
WO2017106326A1 (en) * 2015-12-14 2017-06-22 The Trustees Of The University Of Pennsylvania Aav-anti pcsk9 antibody constructs and uses thereof
CA3018566A1 (en) * 2016-03-21 2017-09-28 David B. Weiner Dna antibody constructs and method of using same
MY192090A (en) 2016-04-13 2022-07-26 Sanofi Sa Trispecific and/or trivalent binding proteins
US20190192692A1 (en) * 2016-05-05 2019-06-27 The Trustees Of The University Of Pennsylvania DNA Monoclonal Antibodies Targeting IL-6 and CD126
SG10202011027QA (en) * 2016-05-05 2020-12-30 Univ Pennsylvania Dna monoclonal antibodies targeting checkpoint molecules
EP3452504A4 (en) * 2016-05-05 2020-07-29 The Trustees of The University of Pennsylvania MONOCLONAL DNA ANTIBODIES TARGETING INFLUENZA VIRUS
SG11201809778TA (en) 2016-05-05 2018-12-28 Univ Pennsylvania Dna antibody constructs for use against pseudomonas aeruginosa
KR102668318B1 (ko) 2016-09-19 2024-05-22 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 지카바이러스에 대항하는 신규한 백신 및 지카바이러스에 대해 사용하기 위한 dna 항체 작제물의 조합
US11286295B2 (en) 2016-10-20 2022-03-29 Sanofi Anti-CHIKV monoclonal antibodies directed against the E2 structural protein
EP3534941A4 (en) * 2016-11-07 2020-07-08 The Wistar Institute Of Anatomy And Biology CONSTRUCTIONS OF ANTI-DNA ANTIBODIES FOR USE AGAINST LYME DISEASE
US11370830B2 (en) 2017-04-07 2022-06-28 The Rockefeller University Neutralizing antibodies that bind to the zika virus domain III envelope region
US11142567B2 (en) * 2017-05-22 2021-10-12 National Cheng Kung University Anti-dengue virus antibody, pharmaceutical composition comprising the same, and uses thereof
US11230592B2 (en) 2017-09-27 2022-01-25 The Wistar Institute Of Anatomy And Biology DNA antibody constructs for use against middle east respiratory syndrome coronavirus
WO2019152602A1 (en) * 2018-01-31 2019-08-08 The Wistar Institute Of Anatomy And Biology Structurally modified flavivirus dmabs
KR20200140799A (ko) 2018-01-31 2020-12-16 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 호흡기 세포융합 바이러스에 대하여 사용하기 위한 핵산 항체 작제물
US11613576B2 (en) 2019-04-09 2023-03-28 Sanofi Trispecific binding proteins, methods, and uses thereof
WO2021022107A1 (en) * 2019-07-31 2021-02-04 The Wistar Institute Of Anatomy And Biology Multivalent dna antibody constructs and use thereof
WO2021055760A1 (en) 2019-09-18 2021-03-25 Intergalactic Therapeutics, Inc. Synthetic dna vectors and methods of use
SE544001C2 (en) * 2020-03-17 2021-10-26 Xbrane Biopharma Ab Novel combination of tis sequences, signal peptide sequences and nucleic acid sequences encoding heavy and light chains of an antibody
SE544000C2 (en) * 2020-03-17 2021-10-26 Xbrane Biopharma Ab Novel combination of tis sequence, signal peptide sequence and nucleic acid sequence encoding a recombinant protein
US20230136960A1 (en) * 2020-03-19 2023-05-04 Nature's Toolbox, Inc. Novel MRNA-Based COVID-19 Multi-Valent Vaccine and Methods of Scaled Production of the Same
AU2021271860B2 (en) * 2020-05-14 2025-06-05 Inovio Pharmaceuticals, Inc. Vaccines for recurrent respiratory papillomatosis and methods of using the same
CN116963771A (zh) * 2020-12-02 2023-10-27 托马斯杰弗逊大学 桥粒芯蛋白2-定向嵌合抗原受体(car)构建体和使用方法
WO2026080438A1 (en) * 2024-10-07 2026-04-16 Intuitive Biosciences, Inc. Compositions and methods for detection treatment, and prevention of hiv infection

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI46572C (fi) * 1972-04-07 1973-04-10 Stroemberg Oy Ab Jännitemuuntaja.
US7276488B2 (en) 1997-06-04 2007-10-02 Oxford Biomedica (Uk) Limited Vector system
US20030039635A1 (en) 1998-09-30 2003-02-27 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
CN1334343A (zh) * 2000-07-14 2002-02-06 中国医学科学院肿瘤医院肿瘤研究所 抑制肿瘤生长的新抗体、其衍生物及其应用
US20070037165A1 (en) 2000-09-08 2007-02-15 Applera Corporation Polymorphisms in known genes associated with human disease, methods of detection and uses thereof
WO2004013278A2 (en) * 2002-08-02 2004-02-12 Yuhan Corporation Expression vectors
WO2005017149A1 (en) * 2003-06-03 2005-02-24 Cell Genesys, Inc. Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
CN1480215A (zh) 2003-07-07 2004-03-10 叶新新 Sars病毒抗原抗体复合疫苗及实验动物模型与方法
RU2381234C2 (ru) 2004-05-28 2010-02-10 Эдженсис, Инк. Антитела и родственные молекулы, связывающиеся с белками psca
KR101282396B1 (ko) * 2004-05-28 2013-07-04 어젠시스 인코포레이티드 Ｐｓｃａ 단백질에 결합하는 암 진단용 항체
EP1765846A4 (en) 2004-07-13 2010-02-17 Cell Genesys Inc AAV VECTOR COMPOSITIONS AND ITS USE IN PROCESSES FOR INCREASING IMMUNOGLOBULIN EXPRESSION
UA90480C2 (uk) * 2004-07-22 2010-05-11 Джэнэнтэк, Инк. Фармацевтична композиція, що має протипухлинну активність, яка включає антитіло до her2
JO3000B1 (ar) * 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
CA2598454C (en) 2005-02-18 2013-04-09 Medarex, Inc. Monoclonal antibodies against prostate specific membrane antigen (psma) lacking in fucosyl residues
US20060216722A1 (en) 2005-03-25 2006-09-28 Christer Betsholtz Glomerular expression profiling
CN101595228A (zh) 2005-07-21 2009-12-02 艾博特公司 包括sorf构建体的多基因表达和使用多蛋白、前体蛋白和蛋白酶解的方法
EP2185188B1 (en) 2007-08-22 2014-08-06 Medarex, L.L.C. Site-specific attachment of drugs or other agents to engineered antibodies with c-terminal extensions
CA2598966A1 (en) 2007-09-07 2009-03-07 Institut Pasteur Anti-chikungunya monoclonal antibodies and uses thereof
JP2009171880A (ja) 2008-01-23 2009-08-06 Yokohama City Univ アルツハイマー病における次世代遺伝子治療法・免疫治療法の開発
RU2547586C2 (ru) 2008-03-14 2015-04-10 Трансжене С.А. Антитело против csf-1r
EP2274442B1 (en) 2008-04-04 2016-06-29 The Trustees Of The University Of Pennsylvania Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same
WO2010043977A2 (en) 2008-10-13 2010-04-22 Institute For Research In Biomedicine Dengue virus neutralizing antibodies and uses thereof
US9050375B2 (en) * 2009-07-06 2015-06-09 Hoffmann-La Roche, Inc. Bi-specific digoxigenin binding antibodies
RU2553331C2 (ru) 2009-07-13 2015-06-10 Бхарат Байотек Интернэшнл Лимитед Композиция, применимая в качестве ротавирусной вакцины, и способ ее получения
US20110045534A1 (en) 2009-08-20 2011-02-24 Cell Signaling Technology, Inc. Nucleic Acid Cassette For Producing Recombinant Antibodies
US9175070B2 (en) * 2009-09-25 2015-11-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Neutralizing antibodies to HIV-1 and their use
US8580714B2 (en) * 2009-10-14 2013-11-12 Janssen Biotech, Inc. Methods of affinity maturing antibodies
US8298820B2 (en) 2010-01-26 2012-10-30 The Trustees Of The University Of Pennsylvania Influenza nucleic acid molecules and vaccines made therefrom
AU2011276109A1 (en) * 2010-07-09 2013-01-24 Jv Bio Srl Lipid-conjugated antibodies
EP2591000B1 (en) 2010-07-09 2017-05-17 Janssen Vaccines & Prevention B.V. Anti-human respiratory syncytial virus (rsv) antibodies and methods of use
US8637035B2 (en) 2010-07-16 2014-01-28 Academia Sinica Anti-dengue virus antibodies
WO2012065164A2 (en) 2010-11-12 2012-05-18 The Trustees Of The University Of Pennsylvania Consensus prostate antigens nucleic acid molecule encoding the same and vaccine and uses comprising the same
CA2826199A1 (en) 2011-01-31 2012-08-09 The Trustees Of The University Of Pennsylvania Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof
WO2012106578A1 (en) 2011-02-04 2012-08-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services HIV NEUTRALIZING ANTIBODIES HAVING MUTATIONS IN CONSTANT DOMAIN (Fc)
JP6091435B2 (ja) * 2011-02-22 2017-03-08 カリフォルニア インスティチュート オブ テクノロジー アデノ随伴ウイルス（ａａｖ）ベクターを用いたタンパク質の送達
CN102199218A (zh) * 2011-04-29 2011-09-28 中国人民解放军军事医学科学院基础医学研究所 一种抗Her2抗体-白细胞介素2融合蛋白及其用途
WO2013177533A1 (en) 2012-05-25 2013-11-28 California Institute Of Technology Expression of secreted and cell-surface polypeptides
JP7078350B2 (ja) * 2013-10-28 2022-05-31 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア Ｄｎａ抗体構築物及びその使用方法
EP2931318A4 (en) * 2012-12-13 2016-07-20 Univ Pennsylvania DNA ANTIBODY CONSTRUCTS AND METHODS FOR USE THEREOF
PL2931304T3 (pl) 2012-12-13 2021-11-08 The Trustees Of The University Of Pennsylvania Szczepionka wt1
EP2934577A1 (en) 2012-12-19 2015-10-28 Adimab, LLC Multivalent antibody analogs, and methods of their preparation and use
SG11201604719WA (en) 2013-12-13 2016-07-28 Univ Pennsylvania Dna antibody constructs and method of using same

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