JP2016501535A5 - - Google Patents
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- JP2016501535A5 JP2016501535A5 JP2015548014A JP2015548014A JP2016501535A5 JP 2016501535 A5 JP2016501535 A5 JP 2016501535A5 JP 2015548014 A JP2015548014 A JP 2015548014A JP 2015548014 A JP2015548014 A JP 2015548014A JP 2016501535 A5 JP2016501535 A5 JP 2016501535A5
- Authority
- JP
- Japan
- Prior art keywords
- acid sequence
- nucleic acid
- composition
- recombinant nucleic
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261737094P | 2012-12-13 | 2012-12-13 | |
| US61/737,094 | 2012-12-13 | ||
| US201361881376P | 2013-09-23 | 2013-09-23 | |
| US61/881,376 | 2013-09-23 | ||
| US201361896646P | 2013-10-28 | 2013-10-28 | |
| US61/896,646 | 2013-10-28 | ||
| PCT/US2013/075137 WO2014093894A2 (en) | 2012-12-13 | 2013-12-13 | Dna antibody constructs and method of using same |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019061531A Division JP2019115355A (ja) | 2012-12-13 | 2019-03-27 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2021016537A Division JP2021087433A (ja) | 2012-12-13 | 2021-02-04 | Ｄｎａ抗体構築物およびその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016501535A JP2016501535A (ja) | 2016-01-21 |
| JP2016501535A5 true JP2016501535A5 (enExample) | 2017-02-02 |
| JP6898060B2 JP6898060B2 (ja) | 2021-07-07 |
Family
ID=50935092
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015548014A Expired - Fee Related JP6898060B2 (ja) | 2012-12-13 | 2013-12-13 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2019061531A Pending JP2019115355A (ja) | 2012-12-13 | 2019-03-27 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2020035240A Pending JP2020108381A (ja) | 2012-12-13 | 2020-03-02 | Ｄｎａ抗体構築物及びその使用方法 |
| JP2021016537A Withdrawn JP2021087433A (ja) | 2012-12-13 | 2021-02-04 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2023040876A Pending JP2023080085A (ja) | 2012-12-13 | 2023-03-15 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2023108341A Pending JP2023138998A (ja) | 2012-12-13 | 2023-06-30 | Ｄｎａ抗体構築物及びその使用方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019061531A Pending JP2019115355A (ja) | 2012-12-13 | 2019-03-27 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2020035240A Pending JP2020108381A (ja) | 2012-12-13 | 2020-03-02 | Ｄｎａ抗体構築物及びその使用方法 |
| JP2021016537A Withdrawn JP2021087433A (ja) | 2012-12-13 | 2021-02-04 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2023040876A Pending JP2023080085A (ja) | 2012-12-13 | 2023-03-15 | Ｄｎａ抗体構築物およびその使用方法 |
| JP2023108341A Pending JP2023138998A (ja) | 2012-12-13 | 2023-06-30 | Ｄｎａ抗体構築物及びその使用方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US9994629B2 (enExample) |
| EP (1) | EP2931318A4 (enExample) |
| JP (6) | JP6898060B2 (enExample) |
| KR (4) | KR20230156146A (enExample) |
| CN (1) | CN104853782A (enExample) |
| AU (7) | AU2013358944B2 (enExample) |
| BR (2) | BR112015013700A8 (enExample) |
| CA (1) | CA2889723A1 (enExample) |
| EA (1) | EA201591131A1 (enExample) |
| HK (1) | HK1213481A1 (enExample) |
| MX (4) | MX2015007575A (enExample) |
| MY (1) | MY175708A (enExample) |
| SG (1) | SG10202002718RA (enExample) |
| WO (1) | WO2014093894A2 (enExample) |
| ZA (1) | ZA201503583B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015089492A2 (en) | 2013-12-13 | 2015-06-18 | The Trustees Of The University Of Pennsylvania | Dna antibody constructs and method of using same |
| WO2014093894A2 (en) * | 2012-12-13 | 2014-06-19 | The Trustees Of The University Of Pennsylvania | Dna antibody constructs and method of using same |
| KR20230145241A (ko) * | 2014-10-01 | 2023-10-17 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 항원 및 어쥬번트로서 인터류킨-21을 갖는 백신 |
| MX2017007187A (es) * | 2014-12-01 | 2018-01-30 | Univ Pennsylvania | Construcciones de anticuerpos de adn y metodo para utilizarlas. |
| RS62437B1 (sr) | 2015-10-25 | 2021-11-30 | Sanofi Sa | Trispecifični i/ili trivalentni vezujući proteini za prevenciju ili lečenje hiv infekcije |
| US20180363000A1 (en) * | 2015-12-14 | 2018-12-20 | The Trustees Of The University Of Pennsylvania | Aav-anti pcsk9 antibody constructs and uses thereof |
| KR20180138204A (ko) * | 2016-03-21 | 2018-12-28 | 데이비드 비. 웨이너 | Dna 항체 작제물 및 이의 사용 방법 |
| LT3443006T (lt) | 2016-04-13 | 2023-10-25 | Sanofi | Trispecifiniai ir (arba) trivalenčiai rišantieji baltymai |
| KR20250011241A (ko) * | 2016-05-05 | 2025-01-21 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | Il-6 및 cd126을 표적으로하는 dna 단일 클론 항체 |
| EA201892522A1 (ru) * | 2016-05-05 | 2019-05-31 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Днк-моноклональные антитела, нацеленные на молекулы контрольных точек |
| BR112018072708A2 (pt) * | 2016-05-05 | 2019-02-19 | The Trustees Of The University Of Pennsylvania | molécula de ácido nucleico, composição, e, método para tratar uma infecção por influenza em um sujeito. |
| SG11201809778TA (en) | 2016-05-05 | 2018-12-28 | Univ Pennsylvania | Dna antibody constructs for use against pseudomonas aeruginosa |
| BR112019005378A2 (pt) * | 2016-09-19 | 2019-08-27 | The Trustees Of The University Of Pennsylvania | molécula de ácido nucleico, composição, e, métodos para prevenir ou tratar uma doença e para induzir uma resposta imune |
| TW202300515A (zh) | 2016-10-20 | 2023-01-01 | 法商賽諾菲公司 | 抗ｃｈｉｋｖ抗體及其用途 |
| KR20210117359A (ko) * | 2016-11-07 | 2021-09-28 | 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 | 라임병에 사용하기 위한 dna 항체 작제물 |
| US11370830B2 (en) | 2017-04-07 | 2022-06-28 | The Rockefeller University | Neutralizing antibodies that bind to the zika virus domain III envelope region |
| WO2018217681A1 (en) * | 2017-05-22 | 2018-11-29 | National Cheng Kung University | Anti-dengue virus antibody, pharmaceutical composition comprising the same, and uses thereof |
| WO2019067671A1 (en) * | 2017-09-27 | 2019-04-04 | David Weiner | DNA ANTIBODY CONSTRUCTS FOR USE IN CORONAVIRUS RESPIRATORY SYNDROME OF THE MIDDLE EAST |
| WO2019152602A1 (en) * | 2018-01-31 | 2019-08-08 | The Wistar Institute Of Anatomy And Biology | Structurally modified flavivirus dmabs |
| US11613576B2 (en) | 2019-04-09 | 2023-03-28 | Sanofi | Trispecific binding proteins, methods, and uses thereof |
| US12606612B2 (en) | 2019-07-31 | 2026-04-21 | The Wistar Institute Of Anatomy And Biology | Multivalent DNA antibody constructs and use thereof |
| KR20220128607A (ko) | 2019-09-18 | 2022-09-21 | 인터갈락틱 테라퓨틱스, 인크. | 합성 dna 벡터 및 사용 방법 |
| SE544001C2 (en) * | 2020-03-17 | 2021-10-26 | Xbrane Biopharma Ab | Novel combination of tis sequences, signal peptide sequences and nucleic acid sequences encoding heavy and light chains of an antibody |
| SE544000C2 (en) * | 2020-03-17 | 2021-10-26 | Xbrane Biopharma Ab | Novel combination of tis sequence, signal peptide sequence and nucleic acid sequence encoding a recombinant protein |
| WO2021188906A1 (en) * | 2020-03-19 | 2021-09-23 | Nature's Toolbox, Inc. | Novel mrna-based covid-19 multi-valent vaccine and methods of scaled production of the same |
| BR112022022719A2 (pt) | 2020-05-14 | 2023-02-14 | Inovio Pharmaceuticals Inc | Vacinas para papilomatose respiratória recorrente e métodos de usar a mesma |
| CA3200609A1 (en) * | 2020-12-02 | 2022-06-09 | Adam Eugene Snook | Desmoglein 2-directed chimeric antigen receptor (car) constructs and methods of use |
Family Cites Families (42)
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| FI46572C (fi) * | 1972-04-07 | 1973-04-10 | Stroemberg Oy Ab | Jännitemuuntaja. |
| US7276488B2 (en) | 1997-06-04 | 2007-10-02 | Oxford Biomedica (Uk) Limited | Vector system |
| US20030039635A1 (en) | 1998-09-30 | 2003-02-27 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| CN1334343A (zh) * | 2000-07-14 | 2002-02-06 | 中国医学科学院肿瘤医院肿瘤研究所 | 抑制肿瘤生长的新抗体、其衍生物及其应用 |
| US20070037165A1 (en) | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| AU2003253447A1 (en) * | 2002-08-02 | 2004-02-23 | Yuhan Corporation | Expression vectors |
| WO2005017149A1 (en) * | 2003-06-03 | 2005-02-24 | Cell Genesys, Inc. | Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site |
| CN1480215A (zh) | 2003-07-07 | 2004-03-10 | 叶新新 | Sars病毒抗原抗体复合疫苗及实验动物模型与方法 |
| NZ551627A (en) | 2004-05-28 | 2010-02-26 | Agensys Inc | Antibodies and related molecules that bind to PSCA proteins |
| BR122018073034B1 (pt) * | 2004-05-28 | 2021-10-13 | Agensys, Inc | Anticorpos e moléculas relacionadas que se ligam à proteínas de psca |
| US7714119B2 (en) * | 2004-07-13 | 2010-05-11 | Biosante Pharmaceuticals, Inc. | AAV vector compositions and methods for enhanced expression of immunoglobulins using the same |
| DK1771482T3 (da) * | 2004-07-22 | 2014-10-20 | Genentech Inc | HER2-antistofsammensætning |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| CN101160324B (zh) | 2005-02-18 | 2013-04-24 | 米德列斯公司 | 缺乏岩藻糖残基的抗前列腺特异性膜抗原(psma)单克隆抗体 |
| US20060216722A1 (en) | 2005-03-25 | 2006-09-28 | Christer Betsholtz | Glomerular expression profiling |
| MX2008000985A (es) | 2005-07-21 | 2008-04-07 | Abbott Lab | Expresion de gen multiple que incluye construcciones y metodos sorf (cuadro de lectura abierta simple) con poliproteinas, pro-proteinas y proteolisis. |
| US8865875B2 (en) | 2007-08-22 | 2014-10-21 | Medarex, L.L.C. | Site-specific attachment of drugs or other agents to engineered antibodies with C-terminal extensions |
| CA2598966A1 (en) | 2007-09-07 | 2009-03-07 | Institut Pasteur | Anti-chikungunya monoclonal antibodies and uses thereof |
| JP2009171880A (ja) | 2008-01-23 | 2009-08-06 | Yokohama City Univ | アルツハイマー病における次世代遺伝子治療法・免疫治療法の開発 |
| BRPI0909044B8 (pt) | 2008-03-14 | 2021-05-25 | Transgene Sa | anticorpo que se liga especificamente ao csf-1r humano,composição farmacêutica e uso dos mesmos |
| CA2720166A1 (en) | 2008-04-04 | 2009-10-08 | David B. Weiner | Consensus sequences of chikungunya viral proteins, nucleic acid molecules encoding the same, and compositions and methods for using the same |
| CN108610416B (zh) | 2008-10-13 | 2022-01-14 | 生物医学研究所 | 登革热病毒中和抗体及其用途 |
| WO2011003780A1 (en) | 2009-07-06 | 2011-01-13 | F. Hoffmann-La Roche Ag | Bi-specific digoxigenin binding antibodies |
| CN102470170B (zh) | 2009-07-13 | 2015-03-18 | 巴拉特生物技术国际有限公司 | 用作轮状病毒疫苗的组合物及其方法 |
| US20110045534A1 (en) | 2009-08-20 | 2011-02-24 | Cell Signaling Technology, Inc. | Nucleic Acid Cassette For Producing Recombinant Antibodies |
| CA2774636C (en) * | 2009-09-25 | 2019-05-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to hiv-1 and their use |
| JP2013508287A (ja) * | 2009-10-14 | 2013-03-07 | ヤンセン バイオテツク，インコーポレーテツド | 抗体を親和性成熟する方法 |
| US8298820B2 (en) * | 2010-01-26 | 2012-10-30 | The Trustees Of The University Of Pennsylvania | Influenza nucleic acid molecules and vaccines made therefrom |
| BR112012031638B1 (pt) | 2010-07-09 | 2021-01-12 | Janssen Vaccines & Prevention B.V. | anticorpo anti-rsv ou fragmento de ligação de antígeno do mesmo, anticorpo multivalente, composição farmacêutica, uso de anticorpo ou fragmento de ligação de antígeno, método de detectar infecção por rsv, e, ácido nucleico isolado |
| CN103097413A (zh) * | 2010-07-09 | 2013-05-08 | Jv生物公司 | 脂质缀合抗体 |
| US8637035B2 (en) | 2010-07-16 | 2014-01-28 | Academia Sinica | Anti-dengue virus antibodies |
| JP6077450B2 (ja) | 2010-11-12 | 2017-02-08 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | コンセンサス前立腺抗原、それをコードする核酸分子、ならびにそれを含むワクチンおよび用途 |
| EA033467B1 (ru) * | 2011-01-31 | 2019-10-31 | Univ Pennsylvania | Молекула нуклеиновой кислоты для индукции иммунного ответа против герпесвируса и ее применение |
| WO2012106578A1 (en) | 2011-02-04 | 2012-08-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | HIV NEUTRALIZING ANTIBODIES HAVING MUTATIONS IN CONSTANT DOMAIN (Fc) |
| US8865881B2 (en) | 2011-02-22 | 2014-10-21 | California Institute Of Technology | Delivery of proteins using adeno-associated virus (AAV) vectors |
| CN102199218A (zh) * | 2011-04-29 | 2011-09-28 | 中国人民解放军军事医学科学院基础医学研究所 | 一种抗Her2抗体-白细胞介素2融合蛋白及其用途 |
| WO2013177533A1 (en) | 2012-05-25 | 2013-11-28 | California Institute Of Technology | Expression of secreted and cell-surface polypeptides |
| WO2015089492A2 (en) | 2013-12-13 | 2015-06-18 | The Trustees Of The University Of Pennsylvania | Dna antibody constructs and method of using same |
| WO2014093894A2 (en) | 2012-12-13 | 2014-06-19 | The Trustees Of The University Of Pennsylvania | Dna antibody constructs and method of using same |
| JP7078350B2 (ja) * | 2013-10-28 | 2022-05-31 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Ｄｎａ抗体構築物及びその使用方法 |
| CN104812401B (zh) | 2012-12-13 | 2017-10-13 | 宾夕法尼亚大学理事会 | Wt1疫苗 |
| EP2934577A1 (en) | 2012-12-19 | 2015-10-28 | Adimab, LLC | Multivalent antibody analogs, and methods of their preparation and use |
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2013
- 2013-12-13 WO PCT/US2013/075137 patent/WO2014093894A2/en not_active Ceased
- 2013-12-13 AU AU2013358944A patent/AU2013358944B2/en active Active
- 2013-12-13 EA EA201591131A patent/EA201591131A1/ru unknown
- 2013-12-13 CA CA2889723A patent/CA2889723A1/en active Pending
- 2013-12-13 MX MX2015007575A patent/MX2015007575A/es unknown
- 2013-12-13 KR KR1020237036307A patent/KR20230156146A/ko not_active Ceased
- 2013-12-13 KR KR1020157018712A patent/KR20150093834A/ko not_active Ceased
- 2013-12-13 BR BR112015013700A patent/BR112015013700A8/pt not_active Application Discontinuation
- 2013-12-13 US US14/651,740 patent/US9994629B2/en active Active
- 2013-12-13 KR KR1020217020972A patent/KR20210088741A/ko not_active Ceased
- 2013-12-13 HK HK16101459.4A patent/HK1213481A1/zh unknown
- 2013-12-13 EP EP13863143.7A patent/EP2931318A4/en active Pending
- 2013-12-13 CN CN201380065674.3A patent/CN104853782A/zh active Pending
- 2013-12-13 JP JP2015548014A patent/JP6898060B2/ja not_active Expired - Fee Related
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2014
- 2014-12-13 AU AU2014361811A patent/AU2014361811B2/en active Active
- 2014-12-13 MY MYPI2016702163A patent/MY175708A/en unknown
- 2014-12-13 MX MX2016007722A patent/MX388911B/es unknown
- 2014-12-13 SG SG10202002718RA patent/SG10202002718RA/en unknown
- 2014-12-13 KR KR1020167018560A patent/KR102454610B1/ko active Active
- 2014-12-13 BR BR112016013493-1A patent/BR112016013493B1/pt not_active IP Right Cessation
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2015
- 2015-05-21 ZA ZA2015/03583A patent/ZA201503583B/en unknown
- 2015-06-12 MX MX2022016002A patent/MX2022016002A/es unknown
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2016
- 2016-06-13 MX MX2021015971A patent/MX2021015971A/es unknown
- 2016-11-18 AU AU2016259451A patent/AU2016259451A1/en not_active Abandoned
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2018
- 2018-04-30 AU AU2018202997A patent/AU2018202997A1/en not_active Abandoned
- 2018-06-12 US US16/005,997 patent/US20180346554A1/en not_active Abandoned
- 2018-09-26 US US16/142,457 patent/US11208470B2/en active Active
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2019
- 2019-03-27 JP JP2019061531A patent/JP2019115355A/ja active Pending
- 2019-04-04 AU AU2019202343A patent/AU2019202343B2/en active Active
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2020
- 2020-03-02 JP JP2020035240A patent/JP2020108381A/ja active Pending
- 2020-03-13 AU AU2020201853A patent/AU2020201853B2/en active Active
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2021
- 2021-02-04 JP JP2021016537A patent/JP2021087433A/ja not_active Withdrawn
- 2021-06-03 AU AU2021203643A patent/AU2021203643A1/en not_active Abandoned
- 2021-12-17 US US17/554,642 patent/US20220112273A1/en not_active Abandoned
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2023
- 2023-03-15 JP JP2023040876A patent/JP2023080085A/ja active Pending
- 2023-06-30 JP JP2023108341A patent/JP2023138998A/ja active Pending