MX2015007575A - Construcciones de anticuerpos de adn y metodo para utilizarlas. - Google Patents

Construcciones de anticuerpos de adn y metodo para utilizarlas.

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Publication number
MX2015007575A
MX2015007575A MX2015007575A MX2015007575A MX2015007575A MX 2015007575 A MX2015007575 A MX 2015007575A MX 2015007575 A MX2015007575 A MX 2015007575A MX 2015007575 A MX2015007575 A MX 2015007575A MX 2015007575 A MX2015007575 A MX 2015007575A
Authority
MX
Mexico
Prior art keywords
same
antibody constructs
dna antibody
subject
composition
Prior art date
Application number
MX2015007575A
Other languages
English (en)
Inventor
David B Weiner
Niranjan Sardesai
Karuppiah Muthumani
Seleeke Flingai
Original Assignee
Univ Pennsylvania
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Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of MX2015007575A publication Critical patent/MX2015007575A/es

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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
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    • C12N2740/10011—Retroviridae
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    • C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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Abstract

En la presente se describen composiciones que incluyen secuencias de ácidos nucleicos optimizadas que codifican anticuerpos y fragmentos funcionales de estos, para expresar anticuerpos sintéticos in vivo y métodos para generar anticuerpos sintéticos en un sujeto; la descripción también proporciona métodos para prevenir y/o tratar una enfermedad en un sujeto usando dichas composiciones y métodos.
MX2015007575A 2012-12-13 2013-12-13 Construcciones de anticuerpos de adn y metodo para utilizarlas. MX2015007575A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261737094P 2012-12-13 2012-12-13
US201361881376P 2013-09-23 2013-09-23
US201361896646P 2013-10-28 2013-10-28
PCT/US2013/075137 WO2014093894A2 (en) 2012-12-13 2013-12-13 Dna antibody constructs and method of using same

Publications (1)

Publication Number Publication Date
MX2015007575A true MX2015007575A (es) 2016-03-15

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Application Number Title Priority Date Filing Date
MX2015007575A MX2015007575A (es) 2012-12-13 2013-12-13 Construcciones de anticuerpos de adn y metodo para utilizarlas.
MX2016007722A MX2016007722A (es) 2012-12-13 2014-12-13 Construcciones de anticuerpos de adn y metodo para utilizarlas.
MX2022016002A MX2022016002A (es) 2012-12-13 2015-06-12 Construcciones de anticuerpos de adn y metodo para utilizarlas.
MX2021015971A MX2021015971A (es) 2012-12-13 2016-06-13 Construcciones de anticuerpos de adn y metodo para utilizarlas.

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MX2016007722A MX2016007722A (es) 2012-12-13 2014-12-13 Construcciones de anticuerpos de adn y metodo para utilizarlas.
MX2022016002A MX2022016002A (es) 2012-12-13 2015-06-12 Construcciones de anticuerpos de adn y metodo para utilizarlas.
MX2021015971A MX2021015971A (es) 2012-12-13 2016-06-13 Construcciones de anticuerpos de adn y metodo para utilizarlas.

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US (4) US9994629B2 (es)
EP (1) EP2931318A4 (es)
JP (6) JP6898060B2 (es)
KR (4) KR20150093834A (es)
CN (1) CN104853782A (es)
AU (7) AU2013358944B2 (es)
BR (2) BR112015013700A8 (es)
CA (1) CA2889723A1 (es)
EA (1) EA201591131A1 (es)
HK (1) HK1213481A1 (es)
MX (4) MX2015007575A (es)
MY (1) MY175708A (es)
SG (1) SG10202002718RA (es)
WO (1) WO2014093894A2 (es)
ZA (1) ZA201503583B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11208470B2 (en) 2012-12-13 2021-12-28 The Trustees Of The University Of Pennsylvania DNA antibody constructs and method of using same
US11278619B2 (en) 2014-12-01 2022-03-22 The Trustees Of The University Of Pennsylvania DNA antibody constructs and method of using same

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7078350B2 (ja) 2013-10-28 2022-05-31 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア Ｄｎａ抗体構築物及びその使用方法
WO2015089492A2 (en) 2013-12-13 2015-06-18 The Trustees Of The University Of Pennsylvania Dna antibody constructs and method of using same
AU2015323944B2 (en) * 2014-10-01 2018-11-29 Inovio Pharmaceuticals, Inc. Vaccines having an antigen and interleukin-21 as an adjuvant
AU2016347058B2 (en) 2015-10-25 2023-11-09 Sanofi Trispecific and/or trivalent binding proteins for prevention or treatment of HIV infection
US20180363000A1 (en) * 2015-12-14 2018-12-20 The Trustees Of The University Of Pennsylvania Aav-anti pcsk9 antibody constructs and uses thereof
SG11201808152PA (en) * 2016-03-21 2018-10-30 David Weiner Dna antibody constructs and method of using same
SI3443006T1 (sl) 2016-04-13 2024-01-31 Sanofi Trispecifični in/ali trivalentni vezni proteini
SG10202011027QA (en) * 2016-05-05 2020-12-30 Univ Pennsylvania Dna monoclonal antibodies targeting checkpoint molecules
MX2018013523A (es) * 2016-05-05 2019-06-10 Univ Pennsylvania Anticuerpos monoclonales de adn dirigidos a il-6 y cd126.
CA3023093A1 (en) * 2016-05-05 2017-11-09 The Trustees Of The University Of Pennysylvania Dna monoclonal antibodies targeting influenza virus
SG11201809778TA (en) * 2016-05-05 2018-12-28 Univ Pennsylvania Dna antibody constructs for use against pseudomonas aeruginosa
AU2017329044B2 (en) * 2016-09-19 2023-09-14 Inovio Pharmaceuticals, Inc. Combination of novel vaccines against Zika virus and DNA antibody constructs for use against Zika virus
TWI778985B (zh) 2016-10-20 2022-10-01 法商賽諾菲公司 抗chikv抗體及其用途
KR20190116975A (ko) * 2016-11-07 2019-10-15 더 위스타 인스티튜트 오브 아나토미 앤드 바이올로지 라임병에 사용하기 위한 dna 항체 작제물
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