JP2017528158A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017528158A5 JP2017528158A5 JP2017524110A JP2017524110A JP2017528158A5 JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5 JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- lentiviral vector
- vector
- antigen receptor
- chimeric antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020156063A JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028889P | 2014-07-25 | 2014-07-25 | |
| US62/028,889 | 2014-07-25 | ||
| US201562155811P | 2015-05-01 | 2015-05-01 | |
| US62/155,811 | 2015-05-01 | ||
| EP15306036 | 2015-06-29 | ||
| EP15306036.3 | 2015-06-29 | ||
| PCT/EP2015/067090 WO2016012623A1 (en) | 2014-07-25 | 2015-07-24 | Lentiviral vectors for regulated expression of a chimeric antigen receptor molecule |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Division JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017528158A JP2017528158A (ja) | 2017-09-28 |
| JP2017528158A5 true JP2017528158A5 (enExample) | 2018-08-30 |
| JP6940406B2 JP6940406B2 (ja) | 2021-09-29 |
Family
ID=53514131
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524110A Expired - Fee Related JP6940406B2 (ja) | 2014-07-25 | 2015-07-24 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10752668B2 (enExample) |
| EP (2) | EP3172228B1 (enExample) |
| JP (3) | JP6940406B2 (enExample) |
| CN (2) | CN107531800B (enExample) |
| CA (1) | CA2956385A1 (enExample) |
| WO (1) | WO2016012623A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201404991YA (en) | 2012-02-23 | 2014-09-26 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| RU2761555C2 (ru) * | 2015-10-22 | 2021-12-09 | Джуно Терапьютикс Гмбх | Способы, наборы, средства и устройства для трансдукции |
| WO2017180587A2 (en) * | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| CN108276493B (zh) * | 2016-12-30 | 2023-11-14 | 南京传奇生物科技有限公司 | 一种嵌合抗原受体及其应用 |
| AU2018260380B2 (en) | 2017-04-27 | 2025-02-13 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| IL270361B2 (en) | 2017-05-01 | 2025-04-01 | Univ Pennsylvania | Monoclonal antibodies against alpha-synuclein fibrils |
| EP3697811A1 (en) | 2017-10-20 | 2020-08-26 | Institut Curie | Hook fusion protein for regulating the cellular trafficking of a target protein |
| EP3697809A1 (en) | 2017-10-20 | 2020-08-26 | Institut Curie | Dap10/12 based cars adapted for rush |
| KR20200076732A (ko) | 2017-11-03 | 2020-06-29 | 소렌토 쎄라퓨틱스, 인코포레이티드 | Cd38-지시된 키메라 항원 수용체 작제물 |
| WO2019145796A2 (en) | 2018-01-17 | 2019-08-01 | Aratinga Bio Tnp | Polymer-encapsulated viral vectors for genetic therapy |
| EP3549597A1 (en) * | 2018-04-06 | 2019-10-09 | Heinrich-Heine-Universität Düsseldorf | Synthetic signalling constructs and its use |
| EP3781176A4 (en) * | 2018-04-09 | 2022-05-25 | The Trustees of the University of Pennsylvania | METHODS AND COMPOSITIONS USING A VIRAL VECTOR FOR THE EXPRESSION OF A TRANSGENE AND AN EFFECTOR |
| SG11202009975TA (en) * | 2018-04-12 | 2020-11-27 | Umoja Biopharma Inc | Viral vectors and packaging cell lines |
| BR112021002390A2 (pt) | 2018-08-09 | 2021-05-11 | Juno Therapeutics Inc | processos para gerar células modificadas e suas composições |
| WO2020089343A1 (en) | 2018-10-31 | 2020-05-07 | Juno Therapeutics Gmbh | Methods for selection and stimulation of cells and apparatus for same |
| WO2021009263A1 (en) | 2019-07-16 | 2021-01-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies having specificity for cd38 and uses thereof |
| CN114651003A (zh) | 2019-09-10 | 2022-06-21 | 黑曜石疗法公司 | 用于可调调节的ca2-il15融合蛋白 |
| GB201914611D0 (en) * | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| JP2022552265A (ja) * | 2019-10-11 | 2022-12-15 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 調節可能な細胞局在化のための組換えポリペプチド |
| JP2023517011A (ja) | 2020-03-05 | 2023-04-21 | ネオティーエックス セラピューティクス リミテッド | 免疫細胞を用いて癌を治療するための方法および組成物 |
| WO2022051240A1 (en) * | 2020-09-01 | 2022-03-10 | The Trustees Of The University Of Pennsylvania | Improved generation of lentiviral vectors for t cell transduction using cocal envelope |
| JP2023554542A (ja) | 2020-11-13 | 2023-12-27 | ホーニング バイオサイエンシズ | 目的の分泌性タンパク質または細胞膜固定タンパク質の細胞内輸送を制御するための手段および方法 |
| AR125468A1 (es) * | 2021-04-27 | 2023-07-19 | Novartis Ag | Sistema de producción de vectores virales |
| IT202100011576A1 (it) * | 2021-05-06 | 2022-11-06 | Univ Degli Studi Padova | Nuova sequenza promotore per terapia genica |
| KR20240124919A (ko) | 2021-11-15 | 2024-08-19 | 떼라벡띠스 | 인유두종 바이러스 항원의 발현을 위한 렌티바이러스 벡터 및 이의 hpv 유발 암 치료에 대한 구현 |
| CN119630795A (zh) * | 2022-05-23 | 2025-03-14 | 通用医疗公司 | 用于免疫细胞crispr筛选的方法和组合物 |
| IL318598A (en) | 2022-07-27 | 2025-03-01 | Theravectys | Lentiviral vectors for the expression of human papillomavirus (HPV) antigens and their application in the treatment of HPV-induced cancer |
| US20250025158A1 (en) | 2023-07-21 | 2025-01-23 | Cilag Gmbh International | Systems and subsystems for rolling a surgical instrument |
| EP4624494A1 (en) | 2024-03-29 | 2025-10-01 | Institut Curie | Her2 single domain antibody and uses thereof |
| WO2026020171A2 (en) | 2024-07-19 | 2026-01-22 | Aera Therapeutics, Inc. | Chimeric antigen receptor constructs |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| USRE32011E (en) | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4902614A (en) | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| DE68927933T2 (de) | 1988-09-02 | 1997-08-14 | Dyax Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| DE69129154T2 (de) | 1990-12-03 | 1998-08-20 | Genentech, Inc., South San Francisco, Calif. | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
| DE69233697T2 (de) | 1991-03-01 | 2008-01-24 | Dyax Corp., Cambridge | Verfahren zur Entwicklung von bindenden Mikroproteinen |
| PT100379B (pt) | 1991-04-10 | 1999-01-29 | Scripps Research Inst | Bibliotecas de receptores heterodimericos usando fagomideos |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| DE4135543A1 (de) | 1991-10-28 | 1993-04-29 | Boehringer Mannheim Gmbh | Rekombinantes core-streptavidin |
| CN1367830A (zh) * | 1998-10-05 | 2002-09-04 | 路德维哥癌症研究院 | 癌症相关抗原及其应用 |
| ES2337429T3 (es) | 1999-10-11 | 2010-04-23 | Institut Pasteur | Vectores lentivirales para la preparacion de composiciones inmunoterapeuticas. |
| US6841359B2 (en) * | 2000-10-31 | 2005-01-11 | The General Hospital Corporation | Streptavidin-binding peptides and uses thereof |
| US7754208B2 (en) * | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| JP2005507236A (ja) * | 2001-04-03 | 2005-03-17 | キュラジェン コーポレイション | 抗原性ポリペプチドに結合する新規抗体、抗原をコードする核酸、および使用方法 |
| AU2002307625A1 (en) * | 2002-03-08 | 2003-09-22 | Cueros Industrializados Del Bajio | Method of incorporating heat-stable particles into leather |
| US20050032173A1 (en) * | 2003-08-05 | 2005-02-10 | Mauricio Rojas | Fusion proteins with a membrane translocating sequence and methods of using same to inhibit an immune response |
| US20130266551A1 (en) * | 2003-11-05 | 2013-10-10 | St. Jude Children's Research Hospital, Inc. | Chimeric receptors with 4-1bb stimulatory signaling domain |
| US7265205B2 (en) * | 2005-02-11 | 2007-09-04 | Uti Limited Partnership | Monomeric streptavidin muteins |
| DE602007009954D1 (de) * | 2006-03-22 | 2010-12-02 | Viral Logic Systems Technology | Verfahren zur identifizierung von polypeptid-targets |
| WO2008105968A1 (en) * | 2006-11-03 | 2008-09-04 | Smithkline Beecham Corporation | Novel seh inhibitors and their use |
| EP2147683A1 (en) | 2008-07-25 | 2010-01-27 | DKFZ Deutsches Krebsforschungszentrum | Construct and method for the internalization of cargo molecules into a cell |
| WO2010142785A1 (en) * | 2009-06-11 | 2010-12-16 | Institut Curie | Methods and kits for regulating intracellular trafficking of a target protein |
| JP5897035B2 (ja) * | 2010-12-14 | 2016-03-30 | ユニバーシティ オブ メリーランド,ボルチモア | 汎用の抗タグキメラ抗原受容体発現t細胞及びがんを治療する方法 |
| RU2623161C2 (ru) * | 2011-04-15 | 2017-06-22 | Компуджен Лтд. | Полипептиды и полинуклеотиды и их применение для лечения иммунологических нарушений и рака |
| US20130071414A1 (en) * | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
| EP2817330B1 (en) * | 2012-02-22 | 2020-07-08 | The Trustees of the University of Pennsylvania | Use of icos-based cars to enhance antitumor activity and car persistence |
| LT2884999T (lt) * | 2012-08-20 | 2021-04-12 | Fred Hutchinson Cancer Research Center | Ląstelinės imunoterapijos būdas ir kompozicijos |
| WO2014059173A2 (en) | 2012-10-10 | 2014-04-17 | Sangamo Biosciences, Inc. | T cell modifying compounds and uses thereof |
| NZ759969A (en) * | 2013-12-20 | 2022-12-23 | Fred Hutchinson Cancer Center | Tagged chimeric effector molecules and receptors thereof |
| EP4339287A3 (en) * | 2015-07-31 | 2024-05-22 | Regents Of The University Of Minnesota | Modified cells and methods of therapy |
-
2015
- 2015-07-24 CA CA2956385A patent/CA2956385A1/en active Pending
- 2015-07-24 CN CN201580051938.9A patent/CN107531800B/zh not_active Expired - Fee Related
- 2015-07-24 JP JP2017524110A patent/JP6940406B2/ja not_active Expired - Fee Related
- 2015-07-24 CN CN202110939899.3A patent/CN113846062B/zh not_active Expired - Fee Related
- 2015-07-24 US US15/327,517 patent/US10752668B2/en active Active
- 2015-07-24 WO PCT/EP2015/067090 patent/WO2016012623A1/en not_active Ceased
- 2015-07-24 EP EP15742027.4A patent/EP3172228B1/en not_active Not-in-force
- 2015-07-24 EP EP19159129.6A patent/EP3511413B1/en active Active
-
2020
- 2020-07-17 US US16/931,986 patent/US20210009653A1/en not_active Abandoned
- 2020-09-17 JP JP2020156063A patent/JP7341110B2/ja active Active
-
2023
- 2023-05-10 JP JP2023078059A patent/JP2023113656A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017537622A5 (enExample) | ||
| JP2019527055A5 (enExample) | ||
| JP2016512557A5 (ja) | 二重特異性分子及びそれを用いた方法 | |
| JP2011530309A5 (enExample) | ||
| EP4609876A3 (en) | Anti-human papillomavirus 16 e7 t cell receptors | |
| JP2015529678A5 (enExample) | ||
| JP2019514373A5 (enExample) | ||
| JP2015533841A5 (enExample) | ||
| JP2019509063A5 (enExample) | ||
| JP2016538830A5 (enExample) | ||
| JP2020517635A5 (enExample) | ||
| JP2017538401A5 (enExample) | ||
| JP2013521789A5 (enExample) | ||
| FI3872085T3 (fi) | Esimuotoiset virussekvenssit ja niiden käytöt | |
| RU2015155821A (ru) | Вакцины против малярии | |
| JP2019519529A5 (enExample) | ||
| JP2012095652A5 (enExample) | ||
| JP2014237714A5 (enExample) | ||
| JP2013507907A5 (enExample) | ||
| EA202090738A1 (ru) | Способ безопасного индуцирования иммунитета против rsv | |
| JP2019508044A5 (enExample) | ||
| RU2015135890A (ru) | Композиция вакцины | |
| JP2014532402A5 (enExample) | ||
| JP2024073653A (ja) | 遺伝子改変リンパ球の製造方法 | |
| JP2016520534A5 (enExample) |