JP2014503206A5 - - Google Patents
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- Publication number
- JP2014503206A5 JP2014503206A5 JP2013544747A JP2013544747A JP2014503206A5 JP 2014503206 A5 JP2014503206 A5 JP 2014503206A5 JP 2013544747 A JP2013544747 A JP 2013544747A JP 2013544747 A JP2013544747 A JP 2013544747A JP 2014503206 A5 JP2014503206 A5 JP 2014503206A5
- Authority
- JP
- Japan
- Prior art keywords
- recombinant
- adenoviral
- adenoviral vector
- vector
- antigen protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000013598 vector Substances 0.000 claims 22
- 241000711950 Filoviridae Species 0.000 claims 9
- 102000036639 antigens Human genes 0.000 claims 9
- 108091007433 antigens Proteins 0.000 claims 9
- 241000701161 unidentified adenovirus Species 0.000 claims 5
- 108090000565 Capsid Proteins Proteins 0.000 claims 4
- 102100023321 Ceruloplasmin Human genes 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 241001115402 Ebolavirus Species 0.000 claims 3
- 241000894007 species Species 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 241001115401 Marburgvirus Species 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 230000037452 priming Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42295410P | 2010-12-14 | 2010-12-14 | |
| US61/422,954 | 2010-12-14 | ||
| PCT/US2011/064944 WO2012082918A1 (en) | 2010-12-14 | 2011-12-14 | Adenovirus serotype 26 and serotype 35 filovirus vaccines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016206679A Division JP6268258B2 (ja) | 2010-12-14 | 2016-10-21 | アデノウイルス血清型２６および血清型３５のフィロウイルスワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014503206A JP2014503206A (ja) | 2014-02-13 |
| JP2014503206A5 true JP2014503206A5 (enExample) | 2015-01-29 |
| JP6054876B2 JP6054876B2 (ja) | 2016-12-27 |
Family
ID=46245095
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013544747A Active JP6054876B2 (ja) | 2010-12-14 | 2011-12-14 | アデノウイルス血清型２６および血清型３５のフィロウイルスワクチン |
| JP2016206679A Active JP6268258B2 (ja) | 2010-12-14 | 2016-10-21 | アデノウイルス血清型２６および血清型３５のフィロウイルスワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016206679A Active JP6268258B2 (ja) | 2010-12-14 | 2016-10-21 | アデノウイルス血清型２６および血清型３５のフィロウイルスワクチン |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9701718B2 (enExample) |
| EP (1) | EP2655604B1 (enExample) |
| JP (2) | JP6054876B2 (enExample) |
| KR (1) | KR101879892B1 (enExample) |
| CN (1) | CN103370411B (enExample) |
| AU (1) | AU2011343798B2 (enExample) |
| BR (1) | BR112013014712B1 (enExample) |
| CA (1) | CA2821289C (enExample) |
| DK (1) | DK2655604T3 (enExample) |
| EA (1) | EA029504B1 (enExample) |
| ES (1) | ES2676196T3 (enExample) |
| PL (1) | PL2655604T3 (enExample) |
| WO (1) | WO2012082918A1 (enExample) |
| ZA (1) | ZA201304260B (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012082918A1 (en) | 2010-12-14 | 2012-06-21 | The Goverment Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Adenovirus serotype 26 and serotype 35 filovirus vaccines |
| ZA201608812B (en) | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| EP3160999B1 (en) | 2014-06-26 | 2018-11-28 | Janssen Vaccines & Prevention B.V. | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| MY183072A (en) * | 2014-09-03 | 2021-02-10 | Bavarian Nordic As | Methods and compositions for inducing protective immunity against filovirus infection |
| KR20190062617A (ko) | 2014-09-03 | 2019-06-05 | 버베리안 노딕 에이/에스 | 면역 반응을 증대시키기 위한 방법 및 조성물 |
| ES2865150T3 (es) | 2014-09-26 | 2021-10-15 | Beth Israel Deaconess Medical Ct Inc | Métodos y composiciones para inducir inmunidad protectora contra la infección por el virus de la inmunodeficiencia humana |
| US20180052173A1 (en) | 2015-03-18 | 2018-02-22 | Janssen Vaccines & Prevention B.V. | Assays for recombinant expression systems |
| EP3584252B1 (en) | 2015-12-15 | 2021-08-25 | Janssen Vaccines & Prevention B.V. | Human immunodeficiency virus antigens, vectors, compositions, and methods of use thereof |
| WO2018053356A1 (en) | 2016-09-16 | 2018-03-22 | International Flavors & Fragrances Inc. | Microcapsule compositions stabilized with viscosity control agents |
| BR112018016806B1 (pt) | 2016-02-18 | 2021-11-16 | International Flavors & Fragrances Inc. | Composiqao de microcapsula, e, produtos de consumidor |
| ES2876160T3 (es) | 2016-03-18 | 2021-11-12 | Int Flavors & Fragrances Inc | Microcápsulas de sílice y métodos para prepararlas |
| WO2017216288A1 (en) | 2016-06-16 | 2017-12-21 | Janssen Vaccines & Prevention B.V. | Hiv vaccine formulation |
| WO2018006089A1 (en) | 2016-07-01 | 2018-01-04 | International Flavors & Fragrances Inc. | Stable microcapsule compositions |
| EP3484507A1 (en) | 2016-07-15 | 2019-05-22 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against a marburg virus infection |
| US10925955B2 (en) | 2016-07-15 | 2021-02-23 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against a Marburg virus infection |
| US20180085291A1 (en) | 2016-09-28 | 2018-03-29 | International Flavors & Fragrances Inc. | Microcapsule compositions containing amino silicone |
| EP3606553A1 (en) | 2017-04-06 | 2020-02-12 | Janssen Vaccines & Prevention B.V. | Mva-bn and ad26.zebov or ad26.filo prime-boost regimen |
| US20180346648A1 (en) | 2017-05-30 | 2018-12-06 | International Flavors & Fragrances Inc. | Branched polyethyleneimine microcapsules |
| US11229693B2 (en) | 2017-06-15 | 2022-01-25 | Janssen Vaccines & Prevention B.V. | Poxvirus vectors encoding HIV antigens, and methods of use thereof |
| WO2019018724A1 (en) | 2017-07-21 | 2019-01-24 | Janssen Vaccines & Prevention B.V. | METHODS FOR SAFE INDUCTION OF MULTICLADED CROSS-IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN HUMAN BEINGS |
| US11235051B2 (en) | 2017-07-28 | 2022-02-01 | Janssen Vaccines & Prevention B.V. | Methods and compositions for heterologous repRNA immunizations |
| WO2019099970A1 (en) | 2017-11-20 | 2019-05-23 | Janssen Pharmaceuticals Inc. | Method of providing safe administration of adenoviral vectors encoding a zika virus antigen |
| BR112020012273A2 (pt) | 2017-12-19 | 2020-11-24 | Janssen Sciences Ireland Unlimited Company | métodos e composições para induzir uma resposta imune contra o vírus da hepatite b (hbv) |
| EP3784707B1 (en) | 2018-04-27 | 2025-12-24 | International Flavors & Fragrances Inc. | Stable polyurea microcapsule compositions |
| CN112437684A (zh) | 2018-07-20 | 2021-03-02 | 扬森疫苗与预防公司 | 以提高的生产率表达寨卡抗原的重组腺病毒载体 |
| CN112770770A (zh) | 2018-09-25 | 2021-05-07 | 扬森疫苗与预防公司 | 共定位施用疫苗组分诱导针对人类免疫缺陷病毒的免疫应答的方法 |
| EP3897955B1 (en) | 2018-12-18 | 2024-02-07 | International Flavors & Fragrances Inc. | Hydroxyethyl cellulose microcapsules |
| MX2021013950A (es) | 2019-05-14 | 2022-01-04 | Janssen Biotech Inc | Eliminacion eficaz de impurezas usando un proceso de diafiltracion. |
| US20230075527A1 (en) | 2020-01-31 | 2023-03-09 | Janssen Pharmaceuticals, Inc | Compositions and Methods for Preventing and Treating Coronavirus Infection - Sars-Cov-2 Vaccines |
| EP4150061A1 (en) | 2020-05-11 | 2023-03-22 | Janssen Pharmaceuticals, Inc. | Stabilized coronavirus spike protein fusion proteins |
| KR20230028517A (ko) | 2020-06-29 | 2023-02-28 | 얀센 백신스 앤드 프리벤션 비.브이. | 호흡기 세포융합 바이러스 감염에 대한 백신 조합물 |
| IL299459A (en) | 2020-07-06 | 2023-02-01 | Janssen Pharmaceuticals Inc | Stabilized corona virus spike protein fusion proteins |
| TW202216190A (zh) | 2020-07-08 | 2022-05-01 | 愛爾蘭商健生科學愛爾蘭無限公司 | 抗hbv之rna複製子疫苗 |
| CN114845733A (zh) * | 2020-08-22 | 2022-08-02 | 俄罗斯联邦卫生部的联邦国家预算机构“以名誉院士N.F.加马列亚命名的国家流行病学和微生物学研究中心” | 抗严重急性呼吸综合征病毒SARS-CoV-2的表达载体 |
| AU2022221983A1 (en) | 2021-02-19 | 2023-08-17 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv fb antigens |
| WO2022175479A1 (en) | 2021-02-19 | 2022-08-25 | Janssen Vaccines & Prevention B.V. | Vaccine combinations against respiratory syncytial virus strain a and b infections |
| MX2023011629A (es) | 2021-04-01 | 2023-10-13 | Janssen Vaccines & Prevention Bv | Proteinas piv3 f prefusion estabilizadas. |
| EP4124383A1 (en) | 2021-07-27 | 2023-02-01 | International Flavors & Fragrances Inc. | Biodegradable microcapsules |
| WO2023020939A1 (en) | 2021-08-17 | 2023-02-23 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| WO2023026182A1 (en) | 2021-08-24 | 2023-03-02 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| EP4154974A1 (en) | 2021-09-23 | 2023-03-29 | International Flavors & Fragrances Inc. | Biodegradable microcapsules |
| WO2023047348A1 (en) | 2021-09-24 | 2023-03-30 | Janssen Pharmaceuticals, Inc. | Stabilized corona virus spike protein fusion proteins |
| WO2023047349A1 (en) | 2021-09-24 | 2023-03-30 | Janssen Pharmaceuticals, Inc. | Stabilized coronavirus spike protein fusion proteins |
| WO2023111725A1 (en) | 2021-12-14 | 2023-06-22 | Janssen Pharmaceuticals, Inc. | Sars-cov-2 vaccines |
| WO2023110618A1 (en) | 2021-12-16 | 2023-06-22 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion hmpv fusion proteins |
| WO2023198815A1 (en) | 2022-04-14 | 2023-10-19 | Janssen Vaccines & Prevention B.V. | Sequential administration of adenoviruses |
| EP4590690A1 (en) | 2022-09-23 | 2025-07-30 | Janssen Vaccines & Prevention B.V. | Pre-fusion human piv1 f proteins |
| WO2024061759A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Stabilized coronavirus s proteins |
| WO2024061753A1 (en) | 2022-09-23 | 2024-03-28 | Janssen Vaccines & Prevention B.V. | Stabilized trimeric class i fusion proteins |
| AU2023355822A1 (en) | 2022-10-06 | 2025-04-17 | Msd International Business Gmbh | Stabilized pre-fusion piv3 f proteins |
| EP4406641A1 (en) | 2023-01-26 | 2024-07-31 | International Flavors & Fragrances Inc. | Biodegradable microcapsules containing low log p fragrance |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6852324B1 (en) * | 1997-12-23 | 2005-02-08 | The United States Of America As Represented By The Department Of Health And Human Services | Immunization for ebola virus infection |
| US6913922B1 (en) | 1999-05-18 | 2005-07-05 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
| WO2003028632A2 (en) * | 2001-10-01 | 2003-04-10 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The | Development of a preventive vaccine for filovirus infection in primates |
| BR0308783A (pt) | 2002-04-25 | 2005-01-04 | Crucell Holland Bv | Vetor de adenovìrus recombinante, método para produzir um vetor de adenovìrus recombinante, composição farmacêutica, método para tratar um corpo humano, e, kit de partes |
| PL208588B1 (pl) | 2002-04-25 | 2011-05-31 | Crucell Holland Bv | Rekombinowane adenowirusy, wyizolowane kwasy nukleinowe, komórki pakujące oraz sposoby zwiększania stabilności i/lub pojemności upakowania rekombinowanego adenowirusa |
| WO2004037294A2 (en) * | 2002-10-23 | 2004-05-06 | Crucell Holland B.V. | New settings for recombinant adenoviral-based vaccines |
| WO2005012538A2 (en) * | 2003-08-01 | 2005-02-10 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Accelerated vaccination |
| WO2006037038A1 (en) * | 2004-09-27 | 2006-04-06 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Optimized vaccines to provide protection against ebola and other viruses |
| AP2351A (en) | 2004-10-13 | 2012-01-25 | Crucell Holland Bv | Improved adenoviral vectors and uses thereof. |
| ES2358523T3 (es) * | 2004-10-13 | 2011-05-11 | Crucell Holland B.V. | Vectores adenovirales mejorados y usos de los mismos. |
| MX2007004031A (es) * | 2004-10-14 | 2007-11-08 | Crucell Holland Bv | Vacunas de cebado/refuerzo contra el paludismo. |
| WO2007104792A2 (en) * | 2006-03-16 | 2007-09-20 | Crucell Holland B.V. | Recombinant adenoviruses based on serotype 26 and 48, and use thereof |
| EP1998804B1 (en) * | 2006-03-27 | 2014-04-16 | Crucell Holland B.V. | Compositions comprising a recombinant adenovirus and an adjuvant |
| US20110091496A1 (en) * | 2008-01-19 | 2011-04-21 | Graham Barney S | Methods and compositions for the delivery of vaccines to disrupted epithelium |
| WO2012082918A1 (en) | 2010-12-14 | 2012-06-21 | The Goverment Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Adenovirus serotype 26 and serotype 35 filovirus vaccines |
-
2011
- 2011-12-14 WO PCT/US2011/064944 patent/WO2012082918A1/en not_active Ceased
- 2011-12-14 JP JP2013544747A patent/JP6054876B2/ja active Active
- 2011-12-14 EP EP11849865.8A patent/EP2655604B1/en active Active
- 2011-12-14 PL PL11849865T patent/PL2655604T3/pl unknown
- 2011-12-14 CA CA2821289A patent/CA2821289C/en active Active
- 2011-12-14 BR BR112013014712-1A patent/BR112013014712B1/pt not_active IP Right Cessation
- 2011-12-14 US US13/994,532 patent/US9701718B2/en active Active
- 2011-12-14 DK DK11849865.8T patent/DK2655604T3/en active
- 2011-12-14 AU AU2011343798A patent/AU2011343798B2/en not_active Ceased
- 2011-12-14 EA EA201390866A patent/EA029504B1/ru not_active IP Right Cessation
- 2011-12-14 KR KR1020137016833A patent/KR101879892B1/ko not_active Expired - Fee Related
- 2011-12-14 ES ES11849865.8T patent/ES2676196T3/es active Active
- 2011-12-14 CN CN201180067429.7A patent/CN103370411B/zh active Active
-
2013
- 2013-06-10 ZA ZA2013/04260A patent/ZA201304260B/en unknown
-
2016
- 2016-10-21 JP JP2016206679A patent/JP6268258B2/ja active Active
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