JP2011530309A5 - - Google Patents
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- Publication number
- JP2011530309A5 JP2011530309A5 JP2011523001A JP2011523001A JP2011530309A5 JP 2011530309 A5 JP2011530309 A5 JP 2011530309A5 JP 2011523001 A JP2011523001 A JP 2011523001A JP 2011523001 A JP2011523001 A JP 2011523001A JP 2011530309 A5 JP2011530309 A5 JP 2011530309A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- mammal
- polypeptide
- protein
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 4
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 2
- 230000006698 induction Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/192,015 | 2008-08-14 | ||
| US12/192,015 US7951377B2 (en) | 2005-08-23 | 2008-08-14 | Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens |
| PCT/US2009/004664 WO2010019262A2 (en) | 2008-08-14 | 2009-08-14 | Polyvalent vaccine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014120307A Division JP2014207910A (ja) | 2008-08-14 | 2014-06-11 | 多価ワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011530309A JP2011530309A (ja) | 2011-12-22 |
| JP2011530309A5 true JP2011530309A5 (enExample) | 2012-10-04 |
Family
ID=41669535
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523001A Pending JP2011530309A (ja) | 2008-08-14 | 2009-08-14 | 多価ワクチン |
| JP2014120307A Pending JP2014207910A (ja) | 2008-08-14 | 2014-06-11 | 多価ワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014120307A Pending JP2014207910A (ja) | 2008-08-14 | 2014-06-11 | 多価ワクチン |
Country Status (9)
| Country | Link |
|---|---|
| US (6) | US7951377B2 (enExample) |
| EP (2) | EP2318430A4 (enExample) |
| JP (2) | JP2011530309A (enExample) |
| CN (1) | CN102177175A (enExample) |
| AU (1) | AU2009282442B2 (enExample) |
| BR (1) | BRPI0917205A2 (enExample) |
| CA (1) | CA2733898C (enExample) |
| IL (1) | IL211184B (enExample) |
| WO (1) | WO2010019262A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7951377B2 (en) | 2005-08-23 | 2011-05-31 | Los Alamos National Security, Llc | Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens |
| CN101969996A (zh) | 2005-08-23 | 2011-02-09 | 加利福尼亚大学董事会 | 多价疫苗 |
| NZ593598A (en) | 2008-11-18 | 2013-02-22 | Beth Israel Hospital | Optimized antiviral vaccines with improved cellular immunogenicity |
| EP2739300B1 (en) | 2011-07-05 | 2019-06-19 | Duke University | N-terminal deleted gp120 immunogens |
| US10092638B2 (en) * | 2011-10-03 | 2018-10-09 | Duke University | GP120 immunogens and methods inducing neutralizing antibodies to human immunodeficiency virus |
| EP2931269B1 (en) | 2012-12-13 | 2019-05-15 | Baylor Research Institute at Dallas | Triheptanoin for the treatment of glucose transporter 1 deficiency |
| WO2015048785A2 (en) * | 2013-09-30 | 2015-04-02 | Los Alamos National Security, Llc | Mosaic conserved region hiv immunogenic polypeptides |
| EP3058065B1 (en) * | 2013-10-16 | 2018-05-02 | New England Biolabs, Inc. | Reverse transcriptase with enhanced properties |
| WO2015143193A1 (en) * | 2014-03-19 | 2015-09-24 | Duke University | Swarm immunization with envelopes from ch505 |
| JP2017512499A (ja) * | 2014-03-25 | 2017-05-25 | デューク ユニバーシティ | モザイクhiv−1配列およびその使用 |
| WO2015153638A1 (en) | 2014-03-31 | 2015-10-08 | Duke University | Compositions comprising ch848 envelopes and uses thereof |
| EP3197488A4 (en) | 2014-09-28 | 2018-03-21 | Duke University | Compositions comprising ch505 envelopes, and trimers |
| WO2017151801A1 (en) | 2016-03-01 | 2017-09-08 | Duke University | Compositions comprising hiv envelopes to induce ch235 lineage antibodies |
| US11318197B2 (en) | 2016-03-03 | 2022-05-03 | Duke University | Compositions and methods for inducing HIV-1 antibodies |
| WO2017152146A2 (en) | 2016-03-03 | 2017-09-08 | Duke University | Compositions and methods for inducing hiv-1 antibodies |
| EP3519428A4 (en) | 2016-10-03 | 2020-07-08 | Duke University | METHODS OF IDENTIFYING IMMUNOGENS BY TARGETING IMPROBABLE MUTATIONS |
| EP3526236B1 (en) * | 2016-10-17 | 2025-12-10 | Beth Israel Deaconess Medical Center, Inc. | Signature-based human immunodeficiency virus (hiv) envelope (env) trimer vaccines and methods of using the same |
| US11814413B2 (en) | 2017-05-25 | 2023-11-14 | Duke University | Compositions comprising modified HIV envelopes |
| CA3114870A1 (en) | 2018-10-01 | 2020-04-09 | Duke University | Hiv-1 envelope stabilizing mutations |
| KR20220047277A (ko) | 2019-07-16 | 2022-04-15 | 길리애드 사이언시즈, 인코포레이티드 | Hiv 백신, 및 이의 제조 및 사용 방법 |
| EP4277652A1 (en) | 2021-01-14 | 2023-11-22 | Gilead Sciences, Inc. | Hiv vaccines and methods of using |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US6139843A (en) * | 1991-04-02 | 2000-10-31 | Albert Einstein College Of Medicine Of Yeshiva University | Peptide compositions for the treatment of HIV |
| US6541011B2 (en) * | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| US6503753B1 (en) * | 1998-02-13 | 2003-01-07 | Adan Rios | Method for the development of an HIV vaccine |
| US20030180314A1 (en) * | 1998-07-10 | 2003-09-25 | Degroot Anne | Immunogenic, cross-clade, HIV peptides |
| US7935805B1 (en) * | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
| US6710173B1 (en) * | 1999-06-25 | 2004-03-23 | Progenics Pharmaceuticals, Inc. | Stabilized viral envelope proteins and uses thereof |
| US7655774B2 (en) * | 2000-02-18 | 2010-02-02 | University Of Washington | Ancestral and COT viral sequences, proteins and immunogenic compositions |
| US20040115621A1 (en) * | 2000-02-18 | 2004-06-17 | Allen Rodrigo | Ancestral viruses and vaccines |
| US6733993B2 (en) * | 2000-09-15 | 2004-05-11 | Merck & Co., Inc. | Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-gag, pol, nef and modifications |
| US7195768B2 (en) | 2001-11-07 | 2007-03-27 | Duke University | Polyvalent immunogen |
| EP1461077A4 (en) * | 2001-11-07 | 2006-01-25 | Univ Duke | MULTIPURPOSE IMMUNOGEN |
| EP1608675B1 (en) * | 2003-03-28 | 2011-08-17 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Immunogenic hiv-1 multi-clade, multivalent constructs and methods of their use |
| CA2520768A1 (en) * | 2003-03-28 | 2005-02-10 | Idm Pharma, Inc. | Methods of identifying optimal variants of peptide epitopes |
| CN1913919B (zh) * | 2003-09-15 | 2011-10-19 | 美国政府健康及人类服务部 | 基于hiv多进化枝的env的hiv疫苗 |
| CN1852734B (zh) * | 2003-09-17 | 2010-12-01 | 杜克大学 | 共有/祖先免疫原 |
| WO2005035555A1 (en) * | 2003-10-10 | 2005-04-21 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hiv/siv env chimeras that promote trimerization and maintain targets of neutralizing antibodies |
| US7951377B2 (en) | 2005-08-23 | 2011-05-31 | Los Alamos National Security, Llc | Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens |
| CN101969996A (zh) | 2005-08-23 | 2011-02-09 | 加利福尼亚大学董事会 | 多价疫苗 |
| US20110110977A1 (en) | 2005-10-17 | 2011-05-12 | Barnett Susan W | Multiclade HIV Vaccines |
| WO2012047267A2 (en) | 2010-09-28 | 2012-04-12 | Duke University | Polyvalent immunogen |
-
2008
- 2008-08-14 US US12/192,015 patent/US7951377B2/en not_active Expired - Fee Related
-
2009
- 2009-08-14 AU AU2009282442A patent/AU2009282442B2/en not_active Ceased
- 2009-08-14 CA CA2733898A patent/CA2733898C/en not_active Expired - Fee Related
- 2009-08-14 WO PCT/US2009/004664 patent/WO2010019262A2/en not_active Ceased
- 2009-08-14 CN CN2009801404211A patent/CN102177175A/zh active Pending
- 2009-08-14 EP EP09806982A patent/EP2318430A4/en not_active Withdrawn
- 2009-08-14 JP JP2011523001A patent/JP2011530309A/ja active Pending
- 2009-08-14 EP EP16184203.4A patent/EP3178842B1/en active Active
- 2009-08-14 US US12/737,761 patent/US9044445B2/en not_active Expired - Fee Related
- 2009-08-14 BR BRPI0917205A patent/BRPI0917205A2/pt not_active IP Right Cessation
-
2011
- 2011-02-10 IL IL211184A patent/IL211184B/en active IP Right Grant
- 2011-04-26 US US13/094,734 patent/US9011873B2/en not_active Expired - Fee Related
-
2014
- 2014-06-11 JP JP2014120307A patent/JP2014207910A/ja active Pending
-
2015
- 2015-04-17 US US14/689,995 patent/US9821053B2/en active Active
- 2015-05-29 US US14/726,373 patent/US9844590B2/en active Active
-
2017
- 2017-12-15 US US15/843,233 patent/US20180185471A1/en not_active Abandoned
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