JP2011530309A5 - - Google Patents

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Publication number
JP2011530309A5
JP2011530309A5 JP2011523001A JP2011523001A JP2011530309A5 JP 2011530309 A5 JP2011530309 A5 JP 2011530309A5 JP 2011523001 A JP2011523001 A JP 2011523001A JP 2011523001 A JP2011523001 A JP 2011523001A JP 2011530309 A5 JP2011530309 A5 JP 2011530309A5
Authority
JP
Japan
Prior art keywords
nucleic acid
mammal
polypeptide
protein
vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011523001A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011530309A (ja
Filing date
Publication date
Priority claimed from US12/192,015 external-priority patent/US7951377B2/en
Application filed filed Critical
Publication of JP2011530309A publication Critical patent/JP2011530309A/ja
Publication of JP2011530309A5 publication Critical patent/JP2011530309A5/ja
Pending legal-status Critical Current

Links

JP2011523001A 2008-08-14 2009-08-14 多価ワクチン Pending JP2011530309A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/192,015 2008-08-14
US12/192,015 US7951377B2 (en) 2005-08-23 2008-08-14 Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens
PCT/US2009/004664 WO2010019262A2 (en) 2008-08-14 2009-08-14 Polyvalent vaccine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014120307A Division JP2014207910A (ja) 2008-08-14 2014-06-11 多価ワクチン

Publications (2)

Publication Number Publication Date
JP2011530309A JP2011530309A (ja) 2011-12-22
JP2011530309A5 true JP2011530309A5 (enExample) 2012-10-04

Family

ID=41669535

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011523001A Pending JP2011530309A (ja) 2008-08-14 2009-08-14 多価ワクチン
JP2014120307A Pending JP2014207910A (ja) 2008-08-14 2014-06-11 多価ワクチン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014120307A Pending JP2014207910A (ja) 2008-08-14 2014-06-11 多価ワクチン

Country Status (9)

Country Link
US (6) US7951377B2 (enExample)
EP (2) EP2318430A4 (enExample)
JP (2) JP2011530309A (enExample)
CN (1) CN102177175A (enExample)
AU (1) AU2009282442B2 (enExample)
BR (1) BRPI0917205A2 (enExample)
CA (1) CA2733898C (enExample)
IL (1) IL211184B (enExample)
WO (1) WO2010019262A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7951377B2 (en) 2005-08-23 2011-05-31 Los Alamos National Security, Llc Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens
CN101969996A (zh) 2005-08-23 2011-02-09 加利福尼亚大学董事会 多价疫苗
NZ593598A (en) 2008-11-18 2013-02-22 Beth Israel Hospital Optimized antiviral vaccines with improved cellular immunogenicity
EP2739300B1 (en) 2011-07-05 2019-06-19 Duke University N-terminal deleted gp120 immunogens
US10092638B2 (en) * 2011-10-03 2018-10-09 Duke University GP120 immunogens and methods inducing neutralizing antibodies to human immunodeficiency virus
EP2931269B1 (en) 2012-12-13 2019-05-15 Baylor Research Institute at Dallas Triheptanoin for the treatment of glucose transporter 1 deficiency
WO2015048785A2 (en) * 2013-09-30 2015-04-02 Los Alamos National Security, Llc Mosaic conserved region hiv immunogenic polypeptides
EP3058065B1 (en) * 2013-10-16 2018-05-02 New England Biolabs, Inc. Reverse transcriptase with enhanced properties
WO2015143193A1 (en) * 2014-03-19 2015-09-24 Duke University Swarm immunization with envelopes from ch505
JP2017512499A (ja) * 2014-03-25 2017-05-25 デューク ユニバーシティ モザイクhiv−1配列およびその使用
WO2015153638A1 (en) 2014-03-31 2015-10-08 Duke University Compositions comprising ch848 envelopes and uses thereof
EP3197488A4 (en) 2014-09-28 2018-03-21 Duke University Compositions comprising ch505 envelopes, and trimers
WO2017151801A1 (en) 2016-03-01 2017-09-08 Duke University Compositions comprising hiv envelopes to induce ch235 lineage antibodies
US11318197B2 (en) 2016-03-03 2022-05-03 Duke University Compositions and methods for inducing HIV-1 antibodies
WO2017152146A2 (en) 2016-03-03 2017-09-08 Duke University Compositions and methods for inducing hiv-1 antibodies
EP3519428A4 (en) 2016-10-03 2020-07-08 Duke University METHODS OF IDENTIFYING IMMUNOGENS BY TARGETING IMPROBABLE MUTATIONS
EP3526236B1 (en) * 2016-10-17 2025-12-10 Beth Israel Deaconess Medical Center, Inc. Signature-based human immunodeficiency virus (hiv) envelope (env) trimer vaccines and methods of using the same
US11814413B2 (en) 2017-05-25 2023-11-14 Duke University Compositions comprising modified HIV envelopes
CA3114870A1 (en) 2018-10-01 2020-04-09 Duke University Hiv-1 envelope stabilizing mutations
KR20220047277A (ko) 2019-07-16 2022-04-15 길리애드 사이언시즈, 인코포레이티드 Hiv 백신, 및 이의 제조 및 사용 방법
EP4277652A1 (en) 2021-01-14 2023-11-22 Gilead Sciences, Inc. Hiv vaccines and methods of using

Family Cites Families (21)

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Publication number Priority date Publication date Assignee Title
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US6139843A (en) * 1991-04-02 2000-10-31 Albert Einstein College Of Medicine Of Yeshiva University Peptide compositions for the treatment of HIV
US6541011B2 (en) * 1998-02-11 2003-04-01 Maxygen, Inc. Antigen library immunization
US6503753B1 (en) * 1998-02-13 2003-01-07 Adan Rios Method for the development of an HIV vaccine
US20030180314A1 (en) * 1998-07-10 2003-09-25 Degroot Anne Immunogenic, cross-clade, HIV peptides
US7935805B1 (en) * 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
US6710173B1 (en) * 1999-06-25 2004-03-23 Progenics Pharmaceuticals, Inc. Stabilized viral envelope proteins and uses thereof
US7655774B2 (en) * 2000-02-18 2010-02-02 University Of Washington Ancestral and COT viral sequences, proteins and immunogenic compositions
US20040115621A1 (en) * 2000-02-18 2004-06-17 Allen Rodrigo Ancestral viruses and vaccines
US6733993B2 (en) * 2000-09-15 2004-05-11 Merck & Co., Inc. Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-gag, pol, nef and modifications
US7195768B2 (en) 2001-11-07 2007-03-27 Duke University Polyvalent immunogen
EP1461077A4 (en) * 2001-11-07 2006-01-25 Univ Duke MULTIPURPOSE IMMUNOGEN
EP1608675B1 (en) * 2003-03-28 2011-08-17 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Immunogenic hiv-1 multi-clade, multivalent constructs and methods of their use
CA2520768A1 (en) * 2003-03-28 2005-02-10 Idm Pharma, Inc. Methods of identifying optimal variants of peptide epitopes
CN1913919B (zh) * 2003-09-15 2011-10-19 美国政府健康及人类服务部 基于hiv多进化枝的env的hiv疫苗
CN1852734B (zh) * 2003-09-17 2010-12-01 杜克大学 共有/祖先免疫原
WO2005035555A1 (en) * 2003-10-10 2005-04-21 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hiv/siv env chimeras that promote trimerization and maintain targets of neutralizing antibodies
US7951377B2 (en) 2005-08-23 2011-05-31 Los Alamos National Security, Llc Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens
CN101969996A (zh) 2005-08-23 2011-02-09 加利福尼亚大学董事会 多价疫苗
US20110110977A1 (en) 2005-10-17 2011-05-12 Barnett Susan W Multiclade HIV Vaccines
WO2012047267A2 (en) 2010-09-28 2012-04-12 Duke University Polyvalent immunogen

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