JP2014012688A5 - - Google Patents
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- JP2014012688A5 JP2014012688A5 JP2013168325A JP2013168325A JP2014012688A5 JP 2014012688 A5 JP2014012688 A5 JP 2014012688A5 JP 2013168325 A JP2013168325 A JP 2013168325A JP 2013168325 A JP2013168325 A JP 2013168325A JP 2014012688 A5 JP2014012688 A5 JP 2014012688A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- seq
- sequence
- recombinantly expressed
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66017705P | 2005-03-10 | 2005-03-10 | |
| US60/660,177 | 2005-03-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011290449A Division JP5378497B2 (ja) | 2005-03-10 | 2011-12-29 | 抗メソテリン抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014012688A JP2014012688A (ja) | 2014-01-23 |
| JP2014012688A5 true JP2014012688A5 (enExample) | 2014-06-19 |
| JP5788443B2 JP5788443B2 (ja) | 2015-09-30 |
Family
ID=36992268
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008500966A Expired - Lifetime JP4949373B2 (ja) | 2005-03-10 | 2006-03-09 | 抗メソテリン抗体 |
| JP2011290449A Expired - Lifetime JP5378497B2 (ja) | 2005-03-10 | 2011-12-29 | 抗メソテリン抗体 |
| JP2013168325A Expired - Lifetime JP5788443B2 (ja) | 2005-03-10 | 2013-08-13 | 抗メソテリン抗体 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008500966A Expired - Lifetime JP4949373B2 (ja) | 2005-03-10 | 2006-03-09 | 抗メソテリン抗体 |
| JP2011290449A Expired - Lifetime JP5378497B2 (ja) | 2005-03-10 | 2011-12-29 | 抗メソテリン抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US7592426B2 (enExample) |
| EP (2) | EP1861425B1 (enExample) |
| JP (3) | JP4949373B2 (enExample) |
| AU (2) | AU2006223301B2 (enExample) |
| CA (1) | CA2600505C (enExample) |
| ES (2) | ES2429340T3 (enExample) |
| WO (1) | WO2006099141A2 (enExample) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1648511A1 (en) * | 2003-07-29 | 2006-04-26 | Morphotek, Inc. | Antibodies and methods for generating genetically altered antibodies with enhanced effector function |
| EP3101034A1 (en) | 2004-02-12 | 2016-12-07 | Morphotek, Inc. | Monoclonal antibodies that specifically bind to folate receptor alpha |
| EP1861425B1 (en) | 2005-03-10 | 2012-05-16 | Morphotek, Inc. | Anti-mesothelin antibodies |
| CA2607444C (en) | 2005-04-22 | 2015-03-10 | Morphotek, Inc. | Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells |
| KR100694508B1 (ko) * | 2005-05-24 | 2007-03-13 | 울산대학교 산학협력단 | Ｈｂｂｋ４항체를 포함하는 암 질환 치료용 약학조성물및 이를 이용한 암의 면역치료 방법 |
| US7943133B2 (en) | 2006-02-02 | 2011-05-17 | Boston Biocom Llc | Mesothelin antibody protein fusions and methods of use |
| US7795411B2 (en) | 2006-10-05 | 2010-09-14 | Fred Hutchinson Cancer Research Center | Vectors for expressing in vivo biotinylated recombinant proteins |
| CN111518218A (zh) * | 2006-11-02 | 2020-08-11 | 阿塞勒隆制药公司 | Alk1受体和配体拮抗剂及其用途 |
| ES2526355T3 (es) | 2007-10-01 | 2015-01-09 | Bristol-Myers Squibb Company | Anticuerpos humanos que se adhieren a mesotelina, y usos de los mismos |
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| CA2718321A1 (en) * | 2008-03-27 | 2009-10-01 | Dimiter S. Dimitrov | Human anti-mesothelin monoclonal antibodies |
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| EP2411416A1 (en) * | 2009-03-24 | 2012-02-01 | The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services | Anti-mesothelin antibodies |
| AR076284A1 (es) * | 2009-04-29 | 2011-06-01 | Bayer Schering Pharma Ag | Inmunoconjugados de antimesotelina y usos de los mismos |
| HUE036157T2 (hu) * | 2010-03-30 | 2018-06-28 | Janssen Biotech Inc | Humanizált IL-25 ellenanyagok |
| BR112013014527A2 (pt) | 2010-12-20 | 2017-03-07 | Genentech Inc | anticorpo isolado, ácido nucleico isolado, célula hospedeira, método para produzir um anticorpo, imunoconjugado, formulação farmacêutica, uso do imunoconjugado, método para tratamento de um indivíduo que tem um câncer positivo para mesotelina, para inibição de proliferação de uma célula positiva para mesotelina, para detecção de mesotelina humana em uma amostra biológica e para detectar um câncer positivo para mesotelina |
| US10233240B1 (en) * | 2011-04-18 | 2019-03-19 | The Regents Of The University Of California | Methods for treating cholestatic liver fibrosis |
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| SG11201404354UA (en) * | 2012-02-17 | 2014-10-30 | Seattle Genetics Inc | ANTIBODIES TO INTEGRIN αVβ6 AND USE OF SAME TO TREAT CANCER |
| WO2013142300A2 (en) * | 2012-03-20 | 2013-09-26 | Biogen Idec Ma Inc. | Jcv neutralizing antibodies |
| ES2731757T3 (es) | 2012-03-20 | 2019-11-18 | Biogen Ma Inc | Anticuerpos neutralizantes de JCV |
| EP2828290B1 (en) | 2012-03-23 | 2018-08-15 | The United States of America, represented by the Secretary, Department of Health and Human Services | Anti-mesothelin chimeric antigen receptors |
| WO2014004549A2 (en) | 2012-06-27 | 2014-01-03 | Amgen Inc. | Anti-mesothelin binding proteins |
| EP3327037B1 (en) * | 2012-08-21 | 2019-10-09 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Mesothelin domain-specific monoclonal antibodies and use thereof |
| PT3221356T (pt) | 2014-11-20 | 2020-10-29 | Hoffmann La Roche | Moléculas de ligação ao antigénio biespecíficas ativadoras das células t contra folr1 e cd3 |
| DK3221357T3 (da) | 2014-11-20 | 2020-08-10 | Hoffmann La Roche | Fælles letkæder og fremgangsmåder til anvendelse |
| WO2016126608A1 (en) | 2015-02-02 | 2016-08-11 | Novartis Ag | Car-expressing cells against multiple tumor antigens and uses thereof |
| PL3298033T5 (pl) | 2015-05-18 | 2023-10-30 | TCR2 Therapeutics Inc. | Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych |
| WO2017032293A1 (zh) * | 2015-08-21 | 2017-03-02 | 科济生物医药（上海）有限公司 | 抗间皮素全人抗体以及靶向间皮素的免疫效应细胞 |
| KR101782487B1 (ko) * | 2015-09-24 | 2017-09-27 | 재단법인 목암생명과학연구소 | 신규 항-메소텔린 항체 및 이를 포함하는 조성물 |
| JP2018536389A (ja) * | 2015-10-02 | 2018-12-13 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | メソテリンとｃｄ３に結合する二重特異性細胞活性化抗原結合分子 |
| MX389194B (es) * | 2015-10-06 | 2025-03-20 | Univ Minnesota | Compuestos terapéuticos y métodos. |
| RU2018127657A (ru) | 2015-12-30 | 2020-01-31 | Новартис Аг | Виды терапии на основе иммуноэффекторных клеток с улучшенной эффективностью |
| KR20180118175A (ko) | 2016-03-04 | 2018-10-30 | 노파르티스 아게 | 다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도 |
| JP7015244B2 (ja) | 2016-03-22 | 2022-02-02 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | プロテアーゼ活性化ｔ細胞二重特異性分子 |
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| BR112019002035A2 (pt) | 2016-08-01 | 2019-05-14 | Novartis Ag | tratamento de câncer usando um receptor de antígeno quimérico em combinação com um inibidor de uma molécula pró-macrófago m2 |
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| JP7291396B2 (ja) | 2016-11-22 | 2023-06-15 | ティーシーアール２ セラピューティクス インク． | 融合タンパク質を用いたｔｃｒの再プログラミングのための組成物及び方法 |
| EP4649966A3 (en) | 2016-12-01 | 2026-02-18 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging |
| ES2912408T3 (es) | 2017-01-26 | 2022-05-25 | Novartis Ag | Composiciones de CD28 y métodos para terapia con receptores quiméricos para antígenos |
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-
2006
- 2006-03-09 EP EP06737748A patent/EP1861425B1/en not_active Expired - Lifetime
- 2006-03-09 US US11/373,546 patent/US7592426B2/en active Active
- 2006-03-09 WO PCT/US2006/008598 patent/WO2006099141A2/en not_active Ceased
- 2006-03-09 EP EP10180413.6A patent/EP2322560B1/en not_active Expired - Lifetime
- 2006-03-09 ES ES10180413T patent/ES2429340T3/es not_active Expired - Lifetime
- 2006-03-09 CA CA2600505A patent/CA2600505C/en not_active Expired - Lifetime
- 2006-03-09 JP JP2008500966A patent/JP4949373B2/ja not_active Expired - Lifetime
- 2006-03-09 ES ES06737748T patent/ES2386367T3/es not_active Expired - Lifetime
- 2006-03-09 AU AU2006223301A patent/AU2006223301B2/en not_active Expired
-
2009
- 2009-08-21 US US12/545,369 patent/US8206710B2/en active Active
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2011
- 2011-01-24 AU AU2011200251A patent/AU2011200251B2/en not_active Expired
- 2011-12-29 JP JP2011290449A patent/JP5378497B2/ja not_active Expired - Lifetime
-
2012
- 2012-05-21 US US13/476,656 patent/US8481703B2/en not_active Expired - Lifetime
-
2013
- 2013-03-13 US US13/799,766 patent/US8658173B2/en not_active Expired - Lifetime
- 2013-08-13 JP JP2013168325A patent/JP5788443B2/ja not_active Expired - Lifetime
-
2014
- 2014-01-06 US US14/148,011 patent/US9115197B2/en not_active Expired - Lifetime
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