JP2005523318A5 - - Google Patents
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- Publication number
- JP2005523318A5 JP2005523318A5 JP2003585745A JP2003585745A JP2005523318A5 JP 2005523318 A5 JP2005523318 A5 JP 2005523318A5 JP 2003585745 A JP2003585745 A JP 2003585745A JP 2003585745 A JP2003585745 A JP 2003585745A JP 2005523318 A5 JP2005523318 A5 JP 2005523318A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- viruses
- treatment
- antigen
- antigens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000700605 Viruses Species 0.000 description 12
- 239000000427 antigen Substances 0.000 description 7
- 102000036639 antigens Human genes 0.000 description 7
- 108091007433 antigens Proteins 0.000 description 7
- 238000000034 method Methods 0.000 description 4
- 210000004443 dendritic cell Anatomy 0.000 description 3
- 102000014150 Interferons Human genes 0.000 description 2
- 108010050904 Interferons Proteins 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 229940079322 interferon Drugs 0.000 description 2
- 210000000130 stem cell Anatomy 0.000 description 2
- 238000002255 vaccination Methods 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 description 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical group 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200200590 | 2002-04-19 | ||
| DKPA200200590 | 2002-04-19 | ||
| PCT/EP2003/003994 WO2003088994A2 (en) | 2002-04-19 | 2003-04-16 | Modified vaccinia virus ankara for the vaccination of neonates |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010028940A Division JP2010120955A (ja) | 2002-04-19 | 2010-02-12 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
| JP2011115564A Division JP5690214B2 (ja) | 2002-04-19 | 2011-05-24 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005523318A JP2005523318A (ja) | 2005-08-04 |
| JP2005523318A5 true JP2005523318A5 (enExample) | 2006-06-08 |
| JP4801880B2 JP4801880B2 (ja) | 2011-10-26 |
Family
ID=29225556
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003585745A Expired - Lifetime JP4801880B2 (ja) | 2002-04-19 | 2003-04-16 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
| JP2010028940A Pending JP2010120955A (ja) | 2002-04-19 | 2010-02-12 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
| JP2011115564A Expired - Lifetime JP5690214B2 (ja) | 2002-04-19 | 2011-05-24 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
| JP2014257263A Pending JP2015061876A (ja) | 2002-04-19 | 2014-12-19 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010028940A Pending JP2010120955A (ja) | 2002-04-19 | 2010-02-12 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
| JP2011115564A Expired - Lifetime JP5690214B2 (ja) | 2002-04-19 | 2011-05-24 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
| JP2014257263A Pending JP2015061876A (ja) | 2002-04-19 | 2014-12-19 | 新生仔予防接種用変異ワクシニアウイルスアンカラ |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US7897156B2 (enExample) |
| EP (4) | EP2204179A3 (enExample) |
| JP (4) | JP4801880B2 (enExample) |
| KR (2) | KR101028937B1 (enExample) |
| CN (1) | CN100540051C (enExample) |
| AT (1) | ATE366586T2 (enExample) |
| AU (1) | AU2003239805B2 (enExample) |
| BR (1) | BR0309339A (enExample) |
| CA (1) | CA2478009C (enExample) |
| CY (1) | CY1106848T1 (enExample) |
| DE (1) | DE60314823T3 (enExample) |
| DK (1) | DK1420822T4 (enExample) |
| EA (1) | EA011233B1 (enExample) |
| ES (1) | ES2288609T5 (enExample) |
| IL (1) | IL163701A0 (enExample) |
| MX (1) | MXPA04010353A (enExample) |
| NO (1) | NO336348B1 (enExample) |
| NZ (2) | NZ547776A (enExample) |
| PL (1) | PL220781B1 (enExample) |
| PT (1) | PT1420822E (enExample) |
| SG (1) | SG173216A1 (enExample) |
| UA (1) | UA85371C2 (enExample) |
| WO (1) | WO2003088994A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101676389A (zh) * | 2000-11-23 | 2010-03-24 | 巴法里安诺迪克有限公司 | 改良安卡拉痘苗病毒变体 |
| US7628980B2 (en) * | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| DK1420822T4 (en) * | 2002-04-19 | 2017-10-09 | Bavarian Nordic As | Modified vaccinia virus Ankara for vaccination of newborns |
| WO2004043490A1 (en) * | 2002-11-07 | 2004-05-27 | Government Of The United States Of America As Represented By The Sercretary Of The Department Of Health And Human Services National Institutes Of Health | Smallpox vaccine regimen |
| UA100836C2 (ru) | 2005-02-23 | 2013-02-11 | Бавариан Нордик А/С | Применение модифицированного вируса осповакцины анкара (mva) для быстрой индукции иммунитета против поксвирусных или других инфекционных агентов |
| EP1835031A1 (en) * | 2006-03-14 | 2007-09-19 | Paul-Ehrlich-Institut Bundesamt für Sera und Impfstoffe | Use of a recombinant modified vaccinia virus Ankara (MVA) for the treatment of type I hypersensitivity in a living animal including humans |
| US8268327B2 (en) * | 2007-04-27 | 2012-09-18 | Bavarian Nordic A/S | Immediate protection against pathogens via MVA |
| US20110052627A1 (en) * | 2008-06-20 | 2011-03-03 | Paul Chaplin | Recombinant modified vaccinia virus measles vaccine |
| CA2815727C (en) | 2010-11-05 | 2019-09-10 | Bavarian Nordic A/S | Modulation of immune responses by the poxviral k4 protein |
| CA2829607A1 (en) | 2011-03-11 | 2012-09-20 | Mcmaster University | A method of vaccination comprising a histone deacetylase inhibitor |
| US10973892B2 (en) * | 2012-09-04 | 2021-04-13 | Bavarian Nordic A/S | Methods and compositions for enhancing vaccine immune responses |
| CN105101993A (zh) * | 2013-03-15 | 2015-11-25 | 巴法里安诺迪克有限公司 | 单次高剂量的mva在新生儿和婴儿中诱导保护性免疫反应 |
| US10801070B2 (en) | 2013-11-25 | 2020-10-13 | The Broad Institute, Inc. | Compositions and methods for diagnosing, evaluating and treating cancer |
| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| NZ721908A (en) | 2013-12-20 | 2022-12-23 | Massachusetts Gen Hospital | Combination therapy with neoantigen vaccine |
| US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
| EP4636401A2 (en) | 2014-12-19 | 2025-10-22 | The Broad Institute, Inc. | Methods for profiling the t-cell-receptor repertoire |
| UA113442C2 (xx) | 2015-01-27 | 2017-01-25 | Ентеросорбент | |
| WO2016144564A2 (en) * | 2015-02-25 | 2016-09-15 | Memorial Sloan-Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| CN107847534B (zh) | 2015-04-17 | 2022-10-04 | 纪念斯隆凯特琳癌症中心 | Mva或mvaδe3l作为抗实体瘤的免疫治疗剂的应用 |
| CA2986235A1 (en) | 2015-05-20 | 2016-11-24 | The Broad Institute, Inc. | Shared neoantigens |
| TWI750122B (zh) | 2015-06-09 | 2021-12-21 | 美商博德研究所有限公司 | 用於贅瘤疫苗之調配物及其製備方法 |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| US10736962B2 (en) * | 2016-02-25 | 2020-08-11 | Memorial Sloan Kettering Cancer Center | Recombinant MVA or MVADELE3L expressing human FLT3L and use thereof as immuno-therapeutic agents against solid tumors |
| US10512662B2 (en) | 2016-02-25 | 2019-12-24 | Memorial Sloan Kettering Cancer Center | Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human Flt3L or GM-CSF for cancer immunotherapy |
| AU2017254477A1 (en) | 2016-04-18 | 2018-11-01 | Jennifer G. ABELIN | Improved HLA epitope prediction |
| US11549149B2 (en) | 2017-01-24 | 2023-01-10 | The Broad Institute, Inc. | Compositions and methods for detecting a mutant variant of a polynucleotide |
| US11242509B2 (en) | 2017-05-12 | 2022-02-08 | Memorial Sloan Kettering Cancer Center | Vaccinia virus mutants useful for cancer immunotherapy |
| MX2021003013A (es) | 2018-09-15 | 2021-08-11 | Memorial Sloan Kettering Cancer Center | Poxvirus recombinantes para inmunoterapia contra cáncer. |
| WO2020072700A1 (en) | 2018-10-02 | 2020-04-09 | Dana-Farber Cancer Institute, Inc. | Hla single allele lines |
| US20220062394A1 (en) | 2018-12-17 | 2022-03-03 | The Broad Institute, Inc. | Methods for identifying neoantigens |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| US12394502B2 (en) | 2019-10-02 | 2025-08-19 | The General Hospital Corporation | Method for predicting HLA-binding peptides using protein structural features |
| CN114980920A (zh) | 2019-11-18 | 2022-08-30 | 詹森生物科技公司 | 基于突变体calr和jak2的疫苗及其用途 |
| WO2022009052A2 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| EP4452305A1 (en) * | 2021-12-23 | 2024-10-30 | Bavarian Nordic A/S | Recombinant mva viruses for intraperitoneal administration for treating cancer |
| WO2024015892A1 (en) | 2022-07-13 | 2024-01-18 | The Broad Institute, Inc. | Hla-ii immunopeptidome methods and systems for antigen discovery |
| US12531162B1 (en) * | 2023-05-31 | 2026-01-20 | Northeastern University | Multi-dimensional phenotypic space for genotype to phenotype mapping and intelligent design of cancer drug therapies using a deep learning net |
| US12562256B2 (en) * | 2023-11-07 | 2026-02-24 | New York University | Systems, methods and computer-accessible medium for identifying target pairs for CAR-T therapy |
| FR3160186A1 (fr) | 2024-03-13 | 2025-09-19 | Odimma Therapeutics | Vecteur non-viral pour transcription augmentee |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3914408A (en) * | 1973-10-12 | 1975-10-21 | Univ Nebraska | Vaccine for neonatal calf diarrhea |
| DE2714665A1 (de) * | 1977-04-01 | 1978-10-05 | Mayr Anton | Praeparat zur behandlung von herpes zoster und anderen herpes-infektionen, sowie verfahren zu seiner herstellung |
| US5338683A (en) * | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
| JPS6035647A (ja) † | 1983-08-09 | 1985-02-23 | Nippon Denso Co Ltd | アンチスキツド制御装置 |
| US6248333B1 (en) * | 1990-04-04 | 2001-06-19 | Health Research Inc. | Isolated nucleic acid sequence of equine herpesvirus type 1 glycoprotein D (EHV-1 gD) |
| US5843456A (en) * | 1991-03-07 | 1998-12-01 | Virogenetics Corporation | Alvac poxvirus-rabies compositions and combination compositions and uses |
| US5403582A (en) * | 1993-01-21 | 1995-04-04 | Nippon Zeon Co., Ltd. | Vaccine comprising fowlpox virus recombinants expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus |
| US5405772A (en) * | 1993-06-18 | 1995-04-11 | Amgen Inc. | Medium for long-term proliferation and development of cells |
| US6190655B1 (en) * | 1993-12-03 | 2001-02-20 | Immunex Corporation | Methods of using Flt-3 ligand for exogenous gene transfer |
| DE4405841C1 (de) * | 1994-02-23 | 1995-01-05 | Mayr Anton Prof Dr Med Vet Dr | Multipotente Paramunitätsinducer auf der Basis von Kombinationen von Pockenviruskomponenten, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| AU694519B2 (en) * | 1994-04-29 | 1998-07-23 | Immuno Aktiengesellschaft | Recombinant poxviruses with foreign polynucleotides in essential regions |
| US5753489A (en) * | 1994-11-10 | 1998-05-19 | Immuno Ag | Method for producing viruses and vaccines in serum-free culture |
| US5756341A (en) * | 1994-11-10 | 1998-05-26 | Immuno Ag | Method for controlling the infectivity of viruses |
| UA68327C2 (en) † | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
| DE69739372D1 (de) | 1996-02-21 | 2009-06-04 | Immunity Kft. Genetic | Verfahren und zusammensetzungen zur genetisch schützenden und therapeutischen immunisierung |
| EP0951555A2 (en) * | 1996-09-24 | 1999-10-27 | Bavarian Nordic Research Institute A/S | Recombinant mva virus expressing dengue virus antigens, and the use thereof in vaccines |
| AU5091898A (en) * | 1996-10-25 | 1998-05-15 | Wistar Institute Of Anatomy And Biology, The | Method of vaccinating infants against infections |
| US6204250B1 (en) * | 1996-11-22 | 2001-03-20 | The Mount Sinai Medical Center Of The City Of New York | Immunization of infants |
| GB9711957D0 (en) * | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| GB0023203D0 (en) * | 2000-09-21 | 2000-11-01 | Isis Innovation | Vaccination method |
| AU3910097A (en) | 1997-08-05 | 1999-03-01 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Live recombinant vaccine comprising inefficiently or non-replicating vir us |
| CN1298851C (zh) | 1998-11-18 | 2007-02-07 | 牛津生物医学(英国)有限公司 | 多肽 |
| GB2370571B (en) | 1998-11-18 | 2003-05-07 | Oxford Biomedica Ltd | A modified 5t4 antigen |
| RU2280075C2 (ru) * | 2000-03-14 | 2006-07-20 | Бавариан Нордик А/С | Измененный штамм модифицированного вируса коровьей оспы ankara (mva) |
| BR0111366A (pt) | 2000-05-24 | 2003-05-20 | Merial Sas | Vacina de poxvìrus recombinante do vìrus da sìndrome respiratória e reprodutiva de porcino (prrsv) |
| CA2412050C (en) * | 2000-06-15 | 2011-03-22 | Jeffrey Schlom | A recombinant non-replicating virus expressing gm-csf and uses thereof to enhance immune responses |
| SI21122A (sl) * | 2000-07-11 | 2003-08-31 | Bayer Aktiengesellschaft | Uporaba sevov parapoksvirusa ovis za proizvodnjo antivirusnih zdravil in zdravil proti raku |
| DE10042598A1 (de) * | 2000-08-30 | 2002-03-28 | Gsf Forschungszentrum Umwelt | Rekombinantes MVA mit der Fähigkeit zur Expression des HER-2/Neu-GENS |
| US7628980B2 (en) * | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| US7097842B2 (en) * | 2000-11-23 | 2006-08-29 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| US7445924B2 (en) * | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| CN101676389A (zh) † | 2000-11-23 | 2010-03-24 | 巴法里安诺迪克有限公司 | 改良安卡拉痘苗病毒变体 |
| US20040091995A1 (en) * | 2001-06-15 | 2004-05-13 | Jeffrey Schlom | Recombinant non-replicating virus expressing gm-csf and uses thereof to enhance immune responses |
| AU2002356690B2 (en) * | 2001-12-04 | 2008-07-24 | Bavarian Nordic A/S | Flavivirus NS1 subunit vaccine |
| DK1420822T4 (en) * | 2002-04-19 | 2017-10-09 | Bavarian Nordic As | Modified vaccinia virus Ankara for vaccination of newborns |
| PL218318B1 (pl) * | 2002-05-16 | 2014-11-28 | Bavarian Nordic As | Rekombinowany wirus krowianki Ankara (MVA), zawierająca go komórka, szczepionka lub kompozycja farmaceutyczna, sposób lub zestaw do jego otrzymywania, sekwencja DNA zawierająca genom tego wirusa oraz sposób wykrywania tego wirusa lub komórek nim zainfekowanych |
| EP1664661A4 (en) * | 2003-09-10 | 2008-02-13 | Ra Brands Llc | METHOD OF PRINTING COMPOSITE VENTILATED BAND |
| WO2005046614A2 (en) * | 2003-11-12 | 2005-05-26 | Therion Biologics Corporation | System for treating and preventing breast cancer |
| US7618980B2 (en) * | 2004-07-14 | 2009-11-17 | Bristol-Myers Squibb Company | Pyrrolo(oxo)quinolines as 5HT ligands |
| EP1835031A1 (en) | 2006-03-14 | 2007-09-19 | Paul-Ehrlich-Institut Bundesamt für Sera und Impfstoffe | Use of a recombinant modified vaccinia virus Ankara (MVA) for the treatment of type I hypersensitivity in a living animal including humans |
| EP1925318A1 (en) | 2006-11-20 | 2008-05-28 | Paul-Ehrlich-Institut | Recombinant modified vaccinia virus Ankara (MVA)-based vaccine for the avian flu |
| US8613936B2 (en) * | 2009-03-13 | 2013-12-24 | Bavarian Nordic A/S | Replication deficient recombinant viruses expressing antigens regulated by transcriptional control elements comprising multiple elements |
-
2003
- 2003-04-16 DK DK03732280.7T patent/DK1420822T4/en active
- 2003-04-16 CN CNB038087863A patent/CN100540051C/zh not_active Expired - Lifetime
- 2003-04-16 MX MXPA04010353A patent/MXPA04010353A/es active IP Right Grant
- 2003-04-16 NZ NZ547776A patent/NZ547776A/xx not_active IP Right Cessation
- 2003-04-16 EP EP10158052A patent/EP2204179A3/en not_active Withdrawn
- 2003-04-16 WO PCT/EP2003/003994 patent/WO2003088994A2/en not_active Ceased
- 2003-04-16 EP EP03732280.7A patent/EP1420822B2/en not_active Expired - Lifetime
- 2003-04-16 CA CA2478009A patent/CA2478009C/en not_active Expired - Lifetime
- 2003-04-16 EA EA200401405A patent/EA011233B1/ru not_active IP Right Cessation
- 2003-04-16 KR KR1020047015645A patent/KR101028937B1/ko not_active Expired - Lifetime
- 2003-04-16 BR BR0309339-5A patent/BR0309339A/pt not_active Application Discontinuation
- 2003-04-16 NZ NZ536592A patent/NZ536592A/en not_active IP Right Cessation
- 2003-04-16 AT AT03732280T patent/ATE366586T2/de active
- 2003-04-16 JP JP2003585745A patent/JP4801880B2/ja not_active Expired - Lifetime
- 2003-04-16 PT PT03732280T patent/PT1420822E/pt unknown
- 2003-04-16 EP EP10158054A patent/EP2204180A3/en not_active Withdrawn
- 2003-04-16 SG SG2007001563A patent/SG173216A1/en unknown
- 2003-04-16 UA UA20041008381A patent/UA85371C2/ru unknown
- 2003-04-16 IL IL16370103A patent/IL163701A0/xx unknown
- 2003-04-16 KR KR1020117000242A patent/KR20110017904A/ko not_active Ceased
- 2003-04-16 AU AU2003239805A patent/AU2003239805B2/en not_active Expired
- 2003-04-16 DE DE60314823.9T patent/DE60314823T3/de not_active Expired - Lifetime
- 2003-04-16 EP EP07013067A patent/EP1839672A3/en not_active Withdrawn
- 2003-04-16 PL PL371594A patent/PL220781B1/pl unknown
- 2003-04-16 ES ES03732280.7T patent/ES2288609T5/es not_active Expired - Lifetime
-
2004
- 2004-11-12 NO NO20044941A patent/NO336348B1/no not_active IP Right Cessation
-
2007
- 2007-09-07 CY CY20071101154T patent/CY1106848T1/el unknown
-
2008
- 2008-05-12 US US12/118,841 patent/US7897156B2/en not_active Expired - Fee Related
-
2010
- 2010-02-12 JP JP2010028940A patent/JP2010120955A/ja active Pending
-
2011
- 2011-01-19 US US13/009,636 patent/US8163293B2/en not_active Expired - Fee Related
- 2011-05-24 JP JP2011115564A patent/JP5690214B2/ja not_active Expired - Lifetime
-
2012
- 2012-03-16 US US13/422,028 patent/US20120183574A1/en not_active Abandoned
-
2014
- 2014-12-19 JP JP2014257263A patent/JP2015061876A/ja active Pending
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