JP2009501012A5 - - Google Patents

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Publication number
JP2009501012A5
JP2009501012A5 JP2008520808A JP2008520808A JP2009501012A5 JP 2009501012 A5 JP2009501012 A5 JP 2009501012A5 JP 2008520808 A JP2008520808 A JP 2008520808A JP 2008520808 A JP2008520808 A JP 2008520808A JP 2009501012 A5 JP2009501012 A5 JP 2009501012A5
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JP
Japan
Prior art keywords
region
fusion protein
pvp2
residues
amino acid
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JP2008520808A
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English (en)
Japanese (ja)
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JP5713533B2 (ja
JP2009501012A (ja
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Priority claimed from ES200501733A external-priority patent/ES2310062B1/es
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Publication of JP2009501012A publication Critical patent/JP2009501012A/ja
Publication of JP2009501012A5 publication Critical patent/JP2009501012A5/ja
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Publication of JP5713533B2 publication Critical patent/JP5713533B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2008520808A 2005-07-15 2006-07-14 伝染性ファブリキウス嚢病ウイルス（ｉｂｄｖ）に由来する中空キメラ性ウイルス様粒子、これらの製造および応用 Expired - Fee Related JP5713533B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP200501733 2005-07-15
ES200501733A ES2310062B1 (es) 2005-07-15 2005-07-15 Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones.
PCT/EP2006/006915 WO2007009673A1 (en) 2005-07-15 2006-07-14 Chimeric empty viral-like particles derived from the infectious bursal disease virus (ibdv), process for their production and applications

Publications (3)

Publication Number Publication Date
JP2009501012A JP2009501012A (ja) 2009-01-15
JP2009501012A5 true JP2009501012A5 (enExample) 2009-08-13
JP5713533B2 JP5713533B2 (ja) 2015-05-07

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ID=37662111

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008520808A Expired - Fee Related JP5713533B2 (ja) 2005-07-15 2006-07-14 伝染性ファブリキウス嚢病ウイルス（ｉｂｄｖ）に由来する中空キメラ性ウイルス様粒子、これらの製造および応用

Country Status (9)

Country Link
US (1) US7476387B2 (enExample)
EP (1) EP1904626B1 (enExample)
JP (1) JP5713533B2 (enExample)
CN (1) CN101278043A (enExample)
AT (1) ATE516345T1 (enExample)
AU (1) AU2006271978B2 (enExample)
CA (1) CA2615468C (enExample)
ES (2) ES2310062B1 (enExample)
WO (1) WO2007009673A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2093281A1 (en) * 2008-02-19 2009-08-26 Kapsid Link, S.L. Protein nanocarriers, process for obtaining them and applications
ES2659586T3 (es) * 2008-05-09 2018-03-16 Chimera Pharma S.L.U. Proteínas de fusión quiméricas y partículas similares a virus de VP2 de Birnavirus
WO2011054995A2 (es) 2009-11-06 2011-05-12 Chimera Pharma, S. L. U. VACUNAS PROFILACTICAS DE GRIPE A PARTIR DE CAPSIDAS VIRALES DE BIRNAVIRUS CONTENIENDO EL ANTIGENO M2e DEL VIRUS DE LA GRIPE
JP5795319B2 (ja) * 2009-11-06 2015-10-14 チャイメラ ファーマ エス．エル．ユー．Ｃｈｉｍｅｒａ Ｐｈａｒｍａ Ｓ．Ｌ．Ｕ． ヒトパピローマウイルス抗原を含むビルナウイルスのウイルスカプシドに基づく腫瘍形成を処置するためのワクチン
SG11201401998VA (en) 2011-11-03 2014-05-29 Sentinext Therapeutics Sdn Bhd Vaccines directed against human enteroviruses
US10086062B2 (en) 2012-07-05 2018-10-02 Ohio State Innovation Foundation Infectious pancreatic necrosis virus (IPNV) vaccine compositions
US9732144B2 (en) 2012-07-05 2017-08-15 Ohio State Innovation Foundation Infectious bursal disease (IBDV) vaccine compositions
WO2015101666A1 (en) * 2014-01-03 2015-07-09 Fundación Biofísica Bizkaia VLPs, METHODS FOR THEIR OBTENTION AND APPLICATIONS THEREOF
CN107034198B (zh) * 2015-07-15 2021-03-09 长春百克生物科技股份公司 一种嵌合诺如病毒p颗粒及其制备和应用
CN108624611A (zh) * 2018-05-15 2018-10-09 武汉科前生物股份有限公司 传染性法氏囊病毒病毒样颗粒的制备及其应用
WO2023062182A1 (en) * 2021-10-15 2023-04-20 Aquilón Cyl, S.L. Vaccine compositions against bovine viral diarrhea virus
CN114058524A (zh) * 2021-10-28 2022-02-18 复旦大学 一种法氏囊亚病毒颗粒疫苗及其制备方法

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3585578D1 (de) 1984-06-18 1992-04-16 Chiron Corp Hepatitisoberflaechenantigenpartikelvakzin.
US5614409A (en) 1989-05-30 1997-03-25 Commonwealth Scientific And Industrial Research Organisation Production of IBDV VP2 in highly immunogenic form
US5641490A (en) 1991-03-07 1997-06-24 Virogenetics Corporation Infectious bursal disease virus recombinant poxvirus vaccine
JPH06508623A (ja) 1991-06-19 1994-09-29 エス・アール・アイ・インターナシヨナル 抗ウィルス剤としてのインフルエンザウィルスのｍ−蛋白質ペプチド
EP0597016A4 (en) 1991-07-26 1996-04-24 Virogenetics Corp Infectious bursal disease virus recombinant poxvirus vaccine.
US5658572A (en) 1991-07-26 1997-08-19 Virogenetics Corporation Infectious bursal disease virus recombinant poxvirus vaccine
US5290686A (en) 1991-07-31 1994-03-01 The United States Of America As Represented By The Department Of Health And Human Services Expression of influenza a M2 protein in baculovirus
JPH05194597A (ja) 1991-12-20 1993-08-03 Nippon Seibutsu Kagaku Kenkyusho 防御抗原性を有する伝染性ファブリキウス嚢病ウイルス（ｉｂｄｖ）の粒子製造法
US5605792A (en) 1993-11-04 1997-02-25 The Ohio State University Research Foundation Infectious bursal disease virus VP2 fusion protein expressed by baculovirus, use as diagnostic
US5788970A (en) 1994-03-29 1998-08-04 The University Of Maryland College Park Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon
AT402898B (de) 1994-08-08 1997-09-25 Int Centre Genetic Eng & Bio Molekulares präsentiersystem
EP0783038B1 (fr) 1996-01-02 2007-04-04 Institut Pasteur Pseudo-particules virales recombinantes et applications vaccinales et antitumorales
US5871744A (en) 1996-09-05 1999-02-16 University Of Maryland-Biotechnology Inst. Method for generating birnavirus from synthetic RNA transcripts
US5916879A (en) 1996-11-12 1999-06-29 St. Jude Children's Research Hospital DNA transcription unit vaccines that protect against avian influenza viruses and methods of use thereof
EP0861665A1 (en) 1997-02-03 1998-09-02 Dimminaco Ag/Sa/Ltd. Infectious bursitis vaccine
WO1998050071A1 (en) 1997-05-01 1998-11-12 Chiron Corporation Use of virus-like particles as adjuvants
EP0887412B1 (en) 1997-05-26 2003-10-15 Akzo Nobel N.V. Recombinant birnavirus vaccine
CA2238659C (en) 1997-05-26 2010-12-14 Akzo Nobel N.V. Recombinant birnavirus vaccine
US6596280B1 (en) 1997-07-31 2003-07-22 University Of Maryland Biotechnology Institute Method for generating birnavirus from synthetic RNA transcripts
US6169175B1 (en) 1997-08-06 2001-01-02 Centers For Disease Control And Prevention Preparation and use of recombinant influenza A virus M2 construct vaccines
US6231868B1 (en) 1997-09-30 2001-05-15 University Of Maryland-Biotechnology Institute Method for generating nonpathogenic infections birnavirus from synthetic RNA transcripts
US6171591B1 (en) 1997-12-08 2001-01-09 Pentamer Pharmaceuticals, Inc. Recombinant nodavirus compositions and methods
US6406843B1 (en) 1998-02-27 2002-06-18 University Of Arkansas Poultry virus isolates and method
WO1999050419A2 (en) 1998-03-31 1999-10-07 University Of Maryland Biotechnology Institute A method for generating nonpathogenic, infectious pancreatic necrosis virus (ipnv) from synthetic rna transcripts
US6114112A (en) 1998-05-21 2000-09-05 The Ohio State University Method of making immunogenic compositions for infectious bursal disease virus
ATE314095T1 (de) * 1998-10-21 2006-01-15 Us Health Virusähnliche partikel zur induktion von autoantikörpern
HUP9802974A1 (hu) 1998-12-19 2000-09-28 Mezőgazdasági Biotechnológiai Kutatóközpont Fertőző bursitis elleni DNS-vakcina
EP1980617A1 (en) 1998-12-31 2008-10-15 Novartis Vaccines and Diagnostics, Inc. Improved expression of HIV polypeptides and production of virus-like particles
US6528063B2 (en) * 1999-01-04 2003-03-04 Rahan Meristem Recombinant vaccines against IBDV
EP1069187A1 (en) 1999-07-14 2001-01-17 Stichting Dienst Landbouwkundig Onderzoek Mosaic Infectious Bursal Disease Virus vaccines
FR2806087B1 (fr) 2000-03-07 2002-10-18 Agronomique Inst Nat Rech Particules pseudovirales de rotavirus et leur utilisation pour vectoriser des proteines ou des acides nucleiques
US6872395B2 (en) 2000-04-14 2005-03-29 Wisconsin Alumni Research Foundation Viruses comprising mutant ion channel protein
US20020165176A1 (en) 2000-05-01 2002-11-07 Haynes Joel R. Nucleic acid immunization
WO2001085208A2 (en) * 2000-05-05 2001-11-15 Cytos Biotechnology Ag Molecular antigen arrays and vaccines
EP1296710A4 (en) 2000-06-19 2004-05-12 Rahan Meristem RECOMBINANT VACCINES AGAINST INFECTIOUS BURSITY VIRUS
DK1294892T3 (da) 2000-06-23 2008-01-28 Wyeth Corp Aggregering af vildtype- og kimære influenzaviruslignende partikler (VLP'er)
EP2088197B8 (en) * 2000-10-02 2016-07-20 ID Biomedical Corporation of Quebec Haemophilus influenzae antigens and corresponding DNA fragments
US7449188B2 (en) 2001-01-18 2008-11-11 Vlaams Interuniversitair Instituut Voor Biotechnologie Recombinant oligometric protein complexes with enhanced immunogenic potential
FR2824327B1 (fr) * 2001-05-02 2003-07-11 Agronomique Inst Nat Rech Particules pseudovirales de birnavirus
WO2002096940A2 (en) 2001-05-31 2002-12-05 Id-Lelystad, Institut Voor Dierhouderij En Diergezondheid B.V. Attenuated very virulent infectious bursal disease virus
US6936256B2 (en) 2001-08-10 2005-08-30 University Of Maryland Biotechnology Institute Sub-unit vaccine for infectious pancreatic necrosis virus
AUPR721101A0 (en) * 2001-08-23 2001-09-13 University Of Queensland, The Nucleic acid and polypeptide linked to breast cancer
CA2492823A1 (en) 2001-09-14 2003-03-27 Cytos Biotechnology Ag In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles
EP1450856B1 (en) 2001-09-14 2009-11-11 Cytos Biotechnology AG Packaging of immunostimulatory cpg into virus-like particles: method of preparation and use
US6764684B2 (en) 2001-09-28 2004-07-20 Zeon Corporation Avian herpesvirus-based recombinant infectious bursal disease vaccine
WO2003068813A2 (en) * 2002-02-11 2003-08-21 Shire Biochem Inc Group b streptococcus antigen
AU2003227026A1 (en) 2002-03-01 2003-09-16 Akzo Nobel N.V. An infectious bursal disease virus variant
DK1506222T3 (da) 2002-05-17 2009-07-06 Univ Cape Town Kimæriske, humane papillomavirus16 L1-proteiner omfattende et L2-peptid, viruslignende partikler fremstillet deraf samt en fremgangsmåde til at fremstille partiklerne
BR0311995A (pt) 2002-06-20 2005-04-05 Cytos Biotechnology Ag Partìculas semelhantes a vìrus empacotadas para o uso como adjuvantes: método de preparação e uso
WO2004003143A2 (en) 2002-06-26 2004-01-08 Advanced Bionutrition Corporation Viruses and virus-like particles for multiple antigen and target display
JP4726483B2 (ja) 2002-07-17 2011-07-20 サイトス バイオテクノロジー アーゲー 分子抗原アレイ
JP4731907B2 (ja) 2002-09-16 2011-07-27 アドバンスド バイオニュートリション コーポレーション 受動免疫のための蛋白質およびペプチド発現
BRPI0407877A (pt) 2003-03-07 2006-03-01 Merck & Co Inc conjugado de peptìdeo-proteìna, vacina para a prevenção ou melhora da infecção pelo vìrus influenza, e, método para induzir um resposta imune em um paciente
ES2217967B1 (es) 2003-03-31 2006-01-01 Consejo Sup. Investig. Cientificas Procedimiento de produccion de particulas virales vacias (vlps) del virus inductor de la bursitis infecciosa (ibdv), composiciones necesarias para su puesta a punto y su uso en la elaboracion de vacunas frente al ibdv.
EA012965B1 (ru) 2003-05-28 2010-02-26 Висконсин Эламни Рисёч Фаундэйшн Композиция для получения реассортантного рекомбинантного вируса гриппа, способ получения указанного вируса и реассортантный рекомбинантный вирус гриппа
EP1644034B1 (en) 2003-07-10 2011-01-12 Cytos Biotechnology AG Composition for enhancing an immune response comprising packaged virus-like particles
US8592197B2 (en) 2003-07-11 2013-11-26 Novavax, Inc. Functional influenza virus-like particles (VLPs)
US20050214316A1 (en) 2003-11-13 2005-09-29 Brown Thomas P Methods of characterizing infectious bursal disease virus
ES2307345B1 (es) 2004-01-21 2009-11-13 Consejo Sup. Investig. Cientificas Capsidas vacias quimericas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones.
ES2307346B1 (es) 2004-01-21 2009-11-13 Consejo Sup. Investig. Cientificas Capsidas vacias (vlps(-vp4)) del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones.
ES2242542B1 (es) 2004-04-30 2006-12-16 Consejo Superior De Investigaciones Cientificas Procedimiento para la produccion en levaduras de capsidas virales vacias compuestas por proteinas derivadas de pvp2 del virus causante de la enfermedad de la bursitis infecciosa (ibdv).
US20060024670A1 (en) 2004-05-18 2006-02-02 Luke Catherine J Influenza virus vaccine composition and methods of use
PT1789084E (pt) 2004-09-09 2011-02-22 Novartis Vaccines & Diagnostic Redução de riscos iatrogénicos pontenciais associados às vacinas contra a gripe
MX2007003171A (es) 2004-09-21 2007-05-23 Cytos Biotechnology Ag Particulas tipo virus que comprenden una proteina de fusion de la proteina de cubierta de ap205 y un polipeptido antigenico.
US7244432B2 (en) 2004-12-08 2007-07-17 University Of Maryland Biotechnology Institute Infectious bursal disease virus (IBDV) variant from Georgia

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