ATE516345T1 - Von ibdv (infectious bursal disease virus) abgeleitete chimäre leere virusähnliche partikel, verfahren zu deren herstellung und anwendungen - Google Patents
Von ibdv (infectious bursal disease virus) abgeleitete chimäre leere virusähnliche partikel, verfahren zu deren herstellung und anwendungenInfo
- Publication number
- ATE516345T1 ATE516345T1 AT06762595T AT06762595T ATE516345T1 AT E516345 T1 ATE516345 T1 AT E516345T1 AT 06762595 T AT06762595 T AT 06762595T AT 06762595 T AT06762595 T AT 06762595T AT E516345 T1 ATE516345 T1 AT E516345T1
- Authority
- AT
- Austria
- Prior art keywords
- ibdv
- virus
- particles
- bursal disease
- infectious bursal
- Prior art date
Links
- 241000702626 Infectious bursal disease virus Species 0.000 title abstract 6
- 239000002245 particle Substances 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/045—Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10023—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200501733A ES2310062B1 (es) | 2005-07-15 | 2005-07-15 | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
| PCT/EP2006/006915 WO2007009673A1 (en) | 2005-07-15 | 2006-07-14 | Chimeric empty viral-like particles derived from the infectious bursal disease virus (ibdv), process for their production and applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE516345T1 true ATE516345T1 (de) | 2011-07-15 |
Family
ID=37662111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06762595T ATE516345T1 (de) | 2005-07-15 | 2006-07-14 | Von ibdv (infectious bursal disease virus) abgeleitete chimäre leere virusähnliche partikel, verfahren zu deren herstellung und anwendungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7476387B2 (enExample) |
| EP (1) | EP1904626B1 (enExample) |
| JP (1) | JP5713533B2 (enExample) |
| CN (1) | CN101278043A (enExample) |
| AT (1) | ATE516345T1 (enExample) |
| AU (1) | AU2006271978B2 (enExample) |
| CA (1) | CA2615468C (enExample) |
| ES (2) | ES2310062B1 (enExample) |
| WO (1) | WO2007009673A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2093281A1 (en) * | 2008-02-19 | 2009-08-26 | Kapsid Link, S.L. | Protein nanocarriers, process for obtaining them and applications |
| EP2288618B1 (en) * | 2008-05-09 | 2017-09-20 | Chimera Pharma S.l.u. | Chimeric fusion proteins and virus like particles from birnavirus vp2 |
| WO2011054995A2 (es) | 2009-11-06 | 2011-05-12 | Chimera Pharma, S. L. U. | VACUNAS PROFILACTICAS DE GRIPE A PARTIR DE CAPSIDAS VIRALES DE BIRNAVIRUS CONTENIENDO EL ANTIGENO M2e DEL VIRUS DE LA GRIPE |
| JP5795319B2 (ja) * | 2009-11-06 | 2015-10-14 | チャイメラ ファーマ エス.エル.ユー.Chimera Pharma S.L.U. | ヒトパピローマウイルス抗原を含むビルナウイルスのウイルスカプシドに基づく腫瘍形成を処置するためのワクチン |
| CN104093420B (zh) | 2011-11-03 | 2017-07-28 | 森提耐斯特治疗公司 | 针对人肠道病毒的抗原及疫苗 |
| WO2014008475A2 (en) | 2012-07-05 | 2014-01-09 | The Ohio State University | Compositions and methods related to viral vaccines |
| US10086062B2 (en) | 2012-07-05 | 2018-10-02 | Ohio State Innovation Foundation | Infectious pancreatic necrosis virus (IPNV) vaccine compositions |
| EP3089755A1 (en) * | 2014-01-03 | 2016-11-09 | Fundacion Biofisica Bizkaia | VLPs, METHODS FOR THEIR OBTENTION AND APPLICATIONS THEREOF |
| CN107034198B (zh) * | 2015-07-15 | 2021-03-09 | 长春百克生物科技股份公司 | 一种嵌合诺如病毒p颗粒及其制备和应用 |
| CN108624611A (zh) * | 2018-05-15 | 2018-10-09 | 武汉科前生物股份有限公司 | 传染性法氏囊病毒病毒样颗粒的制备及其应用 |
| WO2023062182A1 (en) * | 2021-10-15 | 2023-04-20 | Aquilón Cyl, S.L. | Vaccine compositions against bovine viral diarrhea virus |
| CN114058524A (zh) * | 2021-10-28 | 2022-02-18 | 复旦大学 | 一种法氏囊亚病毒颗粒疫苗及其制备方法 |
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| EP0174444B1 (en) | 1984-06-18 | 1992-03-11 | Chiron Corporation | Hepatitis surface antigen particle vaccine |
| US5614409A (en) | 1989-05-30 | 1997-03-25 | Commonwealth Scientific And Industrial Research Organisation | Production of IBDV VP2 in highly immunogenic form |
| US5641490A (en) | 1991-03-07 | 1997-06-24 | Virogenetics Corporation | Infectious bursal disease virus recombinant poxvirus vaccine |
| WO1992022575A1 (en) | 1991-06-19 | 1992-12-23 | Sri International | M-protein peptides of influenza virus as antiviral agents |
| JPH06509235A (ja) | 1991-07-26 | 1994-10-20 | ヴァイロジェネティクス コーポレイション | 伝染性ファブリキウス嚢病ウイルス組換えポックスウイルスワクチン |
| US5658572A (en) | 1991-07-26 | 1997-08-19 | Virogenetics Corporation | Infectious bursal disease virus recombinant poxvirus vaccine |
| US5290686A (en) | 1991-07-31 | 1994-03-01 | The United States Of America As Represented By The Department Of Health And Human Services | Expression of influenza a M2 protein in baculovirus |
| JPH05194597A (ja) | 1991-12-20 | 1993-08-03 | Nippon Seibutsu Kagaku Kenkyusho | 防御抗原性を有する伝染性ファブリキウス嚢病ウイルス(ibdv)の粒子製造法 |
| US5605792A (en) | 1993-11-04 | 1997-02-25 | The Ohio State University Research Foundation | Infectious bursal disease virus VP2 fusion protein expressed by baculovirus, use as diagnostic |
| US5788970A (en) | 1994-03-29 | 1998-08-04 | The University Of Maryland College Park | Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon |
| AT402898B (de) | 1994-08-08 | 1997-09-25 | Int Centre Genetic Eng & Bio | Molekulares präsentiersystem |
| ES2282998T3 (es) | 1996-01-02 | 2007-10-16 | Institut Pasteur | Pseudo-particularmente viricas recombinadas y aplicaciomnes vacunales y antitumorales. |
| US5871744A (en) | 1996-09-05 | 1999-02-16 | University Of Maryland-Biotechnology Inst. | Method for generating birnavirus from synthetic RNA transcripts |
| US5916879A (en) | 1996-11-12 | 1999-06-29 | St. Jude Children's Research Hospital | DNA transcription unit vaccines that protect against avian influenza viruses and methods of use thereof |
| EP0861665A1 (en) | 1997-02-03 | 1998-09-02 | Dimminaco Ag/Sa/Ltd. | Infectious bursitis vaccine |
| AU750702B2 (en) | 1997-05-01 | 2002-07-25 | Chiron Corporation | Use of virus-like particles as adjuvants |
| CA2238659C (en) | 1997-05-26 | 2010-12-14 | Akzo Nobel N.V. | Recombinant birnavirus vaccine |
| EP0887412B1 (en) | 1997-05-26 | 2003-10-15 | Akzo Nobel N.V. | Recombinant birnavirus vaccine |
| US6596280B1 (en) | 1997-07-31 | 2003-07-22 | University Of Maryland Biotechnology Institute | Method for generating birnavirus from synthetic RNA transcripts |
| US6169175B1 (en) | 1997-08-06 | 2001-01-02 | Centers For Disease Control And Prevention | Preparation and use of recombinant influenza A virus M2 construct vaccines |
| US6231868B1 (en) | 1997-09-30 | 2001-05-15 | University Of Maryland-Biotechnology Institute | Method for generating nonpathogenic infections birnavirus from synthetic RNA transcripts |
| US6171591B1 (en) | 1997-12-08 | 2001-01-09 | Pentamer Pharmaceuticals, Inc. | Recombinant nodavirus compositions and methods |
| US6406843B1 (en) | 1998-02-27 | 2002-06-18 | University Of Arkansas | Poultry virus isolates and method |
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| US6114112A (en) | 1998-05-21 | 2000-09-05 | The Ohio State University | Method of making immunogenic compositions for infectious bursal disease virus |
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| HUP9802974A1 (hu) | 1998-12-19 | 2000-09-28 | Mezőgazdasági Biotechnológiai Kutatóközpont | Fertőző bursitis elleni DNS-vakcina |
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| EP1069187A1 (en) | 1999-07-14 | 2001-01-17 | Stichting Dienst Landbouwkundig Onderzoek | Mosaic Infectious Bursal Disease Virus vaccines |
| FR2806087B1 (fr) | 2000-03-07 | 2002-10-18 | Agronomique Inst Nat Rech | Particules pseudovirales de rotavirus et leur utilisation pour vectoriser des proteines ou des acides nucleiques |
| AU5533601A (en) | 2000-04-14 | 2001-10-30 | Wisconsin Alumni Res Found | Viruses comprising mutation ion channel protein |
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| WO2001097839A1 (en) | 2000-06-19 | 2001-12-27 | Rahan Meristem | Recombinant vaccines against infectious bursal disease virus |
| EP1294892B1 (en) | 2000-06-23 | 2007-10-17 | Wyeth Holdings Corporation | Assembly of wild-type and chimeric influenza virus-like particles (vlps) |
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| US6936256B2 (en) | 2001-08-10 | 2005-08-30 | University Of Maryland Biotechnology Institute | Sub-unit vaccine for infectious pancreatic necrosis virus |
| AUPR721101A0 (en) * | 2001-08-23 | 2001-09-13 | University Of Queensland, The | Nucleic acid and polypeptide linked to breast cancer |
| ATE447967T1 (de) | 2001-09-14 | 2009-11-15 | Cytos Biotechnology Ag | Verpackung von immunstimulierendem cpg in virusähnlichen partikeln: herstellungsverfahren und verwendung |
| EP1425040A2 (en) | 2001-09-14 | 2004-06-09 | Cytos Biotechnology AG | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
| US6764684B2 (en) | 2001-09-28 | 2004-07-20 | Zeon Corporation | Avian herpesvirus-based recombinant infectious bursal disease vaccine |
| JP2005535287A (ja) * | 2002-02-11 | 2005-11-24 | アイディー バイオメディカル コーポレイション | グループb連鎖球菌抗原 |
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| PT1506222E (pt) | 2002-05-17 | 2009-06-12 | Univ Cape Town | Proteínas l1 quiméricas do papilomavírus humano 16 incluindo um péptido l2, partículas semelhantes a vírus preparadas a partir daquelas e um método de preparação das partículas |
| ATE489969T1 (de) | 2002-06-20 | 2010-12-15 | Cytos Biotechnology Ag | Verpackte virusartige partikel in kombination mit cpg zur verwendung als adjuvantien mit allergenen. herstellungsverfahren und verwendung |
| CA2490866A1 (en) | 2002-06-26 | 2004-01-08 | Advanced Bionutrition Corporation | Viruses and virus-like particles for multiple antigen and target display |
| RU2324704C2 (ru) | 2002-07-17 | 2008-05-20 | Цитос Байотекнолоджи Аг | Молекулярные массивы антигенов |
| WO2004025263A2 (en) | 2002-09-16 | 2004-03-25 | Advanced Bionutrition Corporation | Protein and peptide expression for passive immunity |
| MXPA05009580A (es) | 2003-03-07 | 2005-10-19 | Merck & Co Inc | Vacuna contra el virus de la influenza. |
| ES2217967B1 (es) | 2003-03-31 | 2006-01-01 | Consejo Sup. Investig. Cientificas | Procedimiento de produccion de particulas virales vacias (vlps) del virus inductor de la bursitis infecciosa (ibdv), composiciones necesarias para su puesta a punto y su uso en la elaboracion de vacunas frente al ibdv. |
| JP5215561B2 (ja) | 2003-05-28 | 2013-06-19 | ウィスコンシン アルムニ リサーチ ファンデイション | ワクチン及び遺伝子治療のための高力価組換えインフルエンザ・ウイルス |
| CA2527102A1 (en) | 2003-07-10 | 2005-01-20 | Cytos Biotechnology Ag | Packaged virus-like particles |
| US8592197B2 (en) | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| EP1689858B1 (en) | 2003-11-13 | 2013-05-15 | University Of Georgia Research Foundation, Inc. | Methods of characterizing infectious bursal disease virus |
| ES2307345B1 (es) | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias quimericas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
| ES2307346B1 (es) | 2004-01-21 | 2009-11-13 | Consejo Sup. Investig. Cientificas | Capsidas vacias (vlps(-vp4)) del virus causante de la enfermedad de la bursitis infecciosa (ibdv), su procedimiento de obtencion y aplicaciones. |
| ES2242542B1 (es) | 2004-04-30 | 2006-12-16 | Consejo Superior De Investigaciones Cientificas | Procedimiento para la produccion en levaduras de capsidas virales vacias compuestas por proteinas derivadas de pvp2 del virus causante de la enfermedad de la bursitis infecciosa (ibdv). |
| AU2005248361B2 (en) | 2004-05-18 | 2010-03-11 | Vical Incorporated | Influenza virus vaccine composition and methods of use |
| EP2578229B1 (en) | 2004-09-09 | 2013-07-10 | Novartis Vaccines and Diagnostics GmbH | Decreasing potential iatrogenic risks associated with vaccine antigens |
| BRPI0516953A (pt) | 2004-09-21 | 2008-09-30 | Cytos Biotechnology Ag | partìculas do tipo vìrus compreendendo uma proteìna de fusão da proteìna de revestimento de ap205 e um polipeptìdeo antigênico |
| US7244432B2 (en) | 2004-12-08 | 2007-07-17 | University Of Maryland Biotechnology Institute | Infectious bursal disease virus (IBDV) variant from Georgia |
-
2005
- 2005-07-15 ES ES200501733A patent/ES2310062B1/es not_active Expired - Fee Related
-
2006
- 2006-05-11 US US11/433,847 patent/US7476387B2/en active Active
- 2006-07-14 CA CA2615468A patent/CA2615468C/en active Active
- 2006-07-14 AU AU2006271978A patent/AU2006271978B2/en active Active
- 2006-07-14 JP JP2008520808A patent/JP5713533B2/ja not_active Expired - Fee Related
- 2006-07-14 ES ES06762595T patent/ES2371833T3/es active Active
- 2006-07-14 AT AT06762595T patent/ATE516345T1/de not_active IP Right Cessation
- 2006-07-14 CN CNA2006800342017A patent/CN101278043A/zh active Pending
- 2006-07-14 WO PCT/EP2006/006915 patent/WO2007009673A1/en not_active Ceased
- 2006-07-14 EP EP06762595A patent/EP1904626B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1904626B1 (en) | 2011-07-13 |
| ES2371833T3 (es) | 2012-01-10 |
| US20070015243A1 (en) | 2007-01-18 |
| AU2006271978A1 (en) | 2007-01-25 |
| JP2009501012A (ja) | 2009-01-15 |
| US7476387B2 (en) | 2009-01-13 |
| CA2615468C (en) | 2015-04-14 |
| CN101278043A (zh) | 2008-10-01 |
| EP1904626A1 (en) | 2008-04-02 |
| WO2007009673A1 (en) | 2007-01-25 |
| CA2615468A1 (en) | 2007-01-25 |
| ES2310062B1 (es) | 2009-11-13 |
| ES2310062A1 (es) | 2008-12-16 |
| JP5713533B2 (ja) | 2015-05-07 |
| AU2006271978B2 (en) | 2012-08-02 |
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