JP2016128513A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016128513A5 JP2016128513A5 JP2016068623A JP2016068623A JP2016128513A5 JP 2016128513 A5 JP2016128513 A5 JP 2016128513A5 JP 2016068623 A JP2016068623 A JP 2016068623A JP 2016068623 A JP2016068623 A JP 2016068623A JP 2016128513 A5 JP2016128513 A5 JP 2016128513A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- positions
- use according
- hbv
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161442204P | 2011-02-12 | 2011-02-12 | |
| US61/442,204 | 2011-02-12 | ||
| US201161496945P | 2011-06-14 | 2011-06-14 | |
| US61/496,945 | 2011-06-14 | ||
| US201161507361P | 2011-07-13 | 2011-07-13 | |
| US61/507,361 | 2011-07-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015025534A Division JP5911983B2 (ja) | 2011-02-12 | 2015-02-12 | 慢性b型肝炎感染症のための酵母系治療薬 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017043689A Division JP2017105834A (ja) | 2011-02-12 | 2017-03-08 | 慢性b型肝炎感染症のための酵母系治療薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016128513A JP2016128513A (ja) | 2016-07-14 |
| JP2016128513A5 true JP2016128513A5 (enExample) | 2016-12-22 |
| JP6109989B2 JP6109989B2 (ja) | 2017-04-05 |
Family
ID=46638950
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013553534A Active JP5745102B2 (ja) | 2011-02-12 | 2012-02-09 | 慢性b型肝炎感染症のための酵母系免疫療法組成物 |
| JP2015025534A Active JP5911983B2 (ja) | 2011-02-12 | 2015-02-12 | 慢性b型肝炎感染症のための酵母系治療薬 |
| JP2016068623A Active JP6109989B2 (ja) | 2011-02-12 | 2016-03-30 | 慢性b型肝炎感染症のための酵母系治療薬 |
| JP2017043689A Pending JP2017105834A (ja) | 2011-02-12 | 2017-03-08 | 慢性b型肝炎感染症のための酵母系治療薬 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013553534A Active JP5745102B2 (ja) | 2011-02-12 | 2012-02-09 | 慢性b型肝炎感染症のための酵母系免疫療法組成物 |
| JP2015025534A Active JP5911983B2 (ja) | 2011-02-12 | 2015-02-12 | 慢性b型肝炎感染症のための酵母系治療薬 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017043689A Pending JP2017105834A (ja) | 2011-02-12 | 2017-03-08 | 慢性b型肝炎感染症のための酵母系治療薬 |
Country Status (25)
| Country | Link |
|---|---|
| US (7) | US8877205B2 (enExample) |
| EP (2) | EP2672991B1 (enExample) |
| JP (4) | JP5745102B2 (enExample) |
| KR (1) | KR102026840B1 (enExample) |
| CN (1) | CN103476426B (enExample) |
| AP (1) | AP2013007110A0 (enExample) |
| AU (2) | AU2012214394B2 (enExample) |
| BR (1) | BR112013020425A2 (enExample) |
| CA (1) | CA2827150C (enExample) |
| CL (1) | CL2013002334A1 (enExample) |
| CO (1) | CO6791572A2 (enExample) |
| CR (1) | CR20130424A (enExample) |
| EA (1) | EA028659B1 (enExample) |
| EC (1) | ECSP13012862A (enExample) |
| ES (1) | ES2643389T3 (enExample) |
| HK (1) | HK1248120A1 (enExample) |
| IL (1) | IL227900B (enExample) |
| MA (1) | MA34956B1 (enExample) |
| PE (1) | PE20140844A1 (enExample) |
| PH (1) | PH12013501683A1 (enExample) |
| SG (1) | SG192285A1 (enExample) |
| TW (1) | TWI504608B (enExample) |
| UA (1) | UA112859C2 (enExample) |
| WO (1) | WO2012109404A1 (enExample) |
| ZA (1) | ZA201306481B (enExample) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9254320B2 (en) | 2010-12-17 | 2016-02-09 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| EA032364B1 (ru) | 2011-02-11 | 2019-05-31 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу |
| US9238679B2 (en) * | 2011-02-11 | 2016-01-19 | The Trustees Of The University Of Pennslyvania | Nucleic acid molecule encoding hepatitis B virus core protein and surface antigen protein and vaccine comprising the same |
| JP5745102B2 (ja) | 2011-02-12 | 2015-07-08 | グローブイミューン,インコーポレイテッド | 慢性b型肝炎感染症のための酵母系免疫療法組成物 |
| MX350661B (es) | 2011-03-17 | 2017-09-13 | Us Health | Composiciones inmunoterapeuticas de levadura-brachyuri. |
| CN103732250A (zh) | 2011-06-14 | 2014-04-16 | 全球免疫股份有限公司 | 基于酵母的治疗或预防丁型肝炎病毒感染的组合物和方法 |
| SG10201607663YA (en) | 2011-08-17 | 2016-11-29 | Globeimmune Inc | Yeast-muc1 immunotherapeutic compositions and uses thereof |
| MX365418B (es) | 2012-06-26 | 2019-06-03 | Biodesix Inc | Metodo por espectros de masa para la seleccion y descarte de pacientes de cancer para el tratamiento con terapias generadoras de respuestas inmunitarias. |
| ES2728243T3 (es) | 2012-11-12 | 2019-10-23 | Univ Heidelberg Ruprecht Karls | Lipopéptidos para su uso en el tratamiento de enfermedades hepáticas y enfermedades cardiovasculares |
| AU2014265873B2 (en) | 2013-03-19 | 2019-01-17 | Globeimmune, Inc. | Yeast-based immunotherapy for chordoma |
| TWI626948B (zh) | 2013-03-26 | 2018-06-21 | 環球免疫公司 | 治療或預防人類免疫缺乏病毒感染之組合物及方法 |
| US10226522B2 (en) | 2013-08-30 | 2019-03-12 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of tuberculosis |
| CA2948803A1 (en) * | 2014-04-11 | 2015-10-15 | Globeimmune, Inc. | Yeast-based immunotherapy and type i interferon sensitivity |
| CN107001429B (zh) * | 2014-11-28 | 2022-01-04 | 赛特瑞恩股份有限公司 | 乙型肝炎病毒表面抗原的表位及与其特异性结合以中和乙型肝炎病毒的结合分子 |
| AU2016205208A1 (en) | 2015-01-09 | 2017-07-06 | Etubics Corporation | Methods and compositions for ebola virus vaccination |
| US9670205B2 (en) | 2015-03-04 | 2017-06-06 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
| AU2016303525B2 (en) | 2015-08-03 | 2021-01-21 | Globeimmune, Inc. | Modified yeast-Brachyury immunotherapeutic compositions |
| US20210292327A1 (en) | 2015-08-26 | 2021-09-23 | Gilead Sciences, Inc. | Deuterated toll-like receptor modulators |
| CA3003557A1 (en) * | 2015-11-04 | 2017-05-11 | Hookipa Biotech Ag | Vaccines against hepatitis b virus |
| RS61118B1 (sr) * | 2016-01-12 | 2020-12-31 | Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh | Sredstva i postupci za lečenje hbv |
| BR102017010009A2 (pt) | 2016-05-27 | 2017-12-12 | Gilead Sciences, Inc. | Compounds for the treatment of hepatitis b virus infection |
| EP3276006A1 (en) * | 2016-07-27 | 2018-01-31 | Theravectys | Lentiviral vectors for expression of hepatitis b virus (hbv) antigens |
| WO2018045150A1 (en) | 2016-09-02 | 2018-03-08 | Gilead Sciences, Inc. | 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators |
| AU2017318601B2 (en) | 2016-09-02 | 2020-09-03 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
| CN106421774B (zh) * | 2016-09-08 | 2019-05-28 | 中国科学院生物物理研究所 | PreS1用于制备乙肝疫苗以及治疗慢性乙型肝炎的用途 |
| KR20230010826A (ko) | 2016-10-14 | 2023-01-19 | 프리시젼 바이오사이언시스 인코포레이티드 | B형 간염 바이러스 게놈 내의 인식 서열에 대해 특이적인 조작된 메가뉴클레아제 |
| TW202510891A (zh) | 2017-01-31 | 2025-03-16 | 美商基利科學股份有限公司 | 替諾福韋埃拉酚胺(tenofovir alafenamide)之晶型 |
| UY37581A (es) | 2017-02-02 | 2018-08-31 | Gilead Sciences Inc | Compuestos para el tratamiento de la infección por virus de la hepatitis b |
| GB201705765D0 (en) * | 2017-04-10 | 2017-05-24 | Univ Oxford Innovation Ltd | HBV vaccine |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| EP3607968A4 (en) * | 2017-06-05 | 2021-03-31 | Beacle Inc. | VIRAL-TYPE PARTICLES INTENDED FOR USE TO INDUCE AN IMMUNE RESPONSE AGAINST HBV |
| CN111051305A (zh) | 2017-08-22 | 2020-04-21 | 吉利德科学公司 | 治疗性杂环化合物 |
| EA202091517A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и устройство для доставки вакцин против вируса гепатита b (hbv) |
| CN111836641A (zh) * | 2017-12-19 | 2020-10-27 | 杨森科学爱尔兰无限公司 | 乙型肝炎病毒(hbv)疫苗及其用途 |
| AU2018390825A1 (en) * | 2017-12-19 | 2020-06-18 | Ichor Medical Systems, Inc. | Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines |
| EA202091516A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv) |
| US11021692B2 (en) | 2017-12-19 | 2021-06-01 | Janssen Sciences Ireland Unlimited Company | Hepatitis B virus (HBV) vaccines and uses thereof |
| WO2019123339A1 (en) | 2017-12-20 | 2019-06-27 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
| EP3728283B1 (en) | 2017-12-20 | 2023-11-22 | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. | 3'3' cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
| CR20200347A (es) | 2018-02-13 | 2020-09-23 | Gilead Sciences Inc | Inhibidores pd-1/pd-l1 |
| JP7050165B2 (ja) | 2018-02-26 | 2022-04-07 | ギリアード サイエンシーズ, インコーポレイテッド | Hbv複製阻害剤としての置換ピロリジン化合物 |
| KR20250136930A (ko) | 2018-03-06 | 2025-09-16 | 프레시전 인코포레이티드 | 사람 파필로마바이러스 백신 및 이의 용도 |
| IL277128B2 (en) * | 2018-03-06 | 2025-11-01 | Precigen Inc | Hepatitis b vaccines and uses of the same |
| US10870691B2 (en) | 2018-04-05 | 2020-12-22 | Gilead Sciences, Inc. | Antibodies and fragments thereof that bind hepatitis B virus protein X |
| TWI833744B (zh) | 2018-04-06 | 2024-03-01 | 捷克科學院有機化學與生物化學研究所 | 3'3'-環二核苷酸 |
| TWI818007B (zh) | 2018-04-06 | 2023-10-11 | 捷克科學院有機化學與生物化學研究所 | 2'3'-環二核苷酸 |
| TW202005654A (zh) | 2018-04-06 | 2020-02-01 | 捷克科學院有機化學與生物化學研究所 | 2,2,─環二核苷酸 |
| US11142750B2 (en) | 2018-04-12 | 2021-10-12 | Precision Biosciences, Inc. | Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome |
| TWI712412B (zh) | 2018-04-19 | 2020-12-11 | 美商基利科學股份有限公司 | Pd‐1/pd‐l1抑制劑 |
| US20190359645A1 (en) | 2018-05-03 | 2019-11-28 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2'3'-cyclic dinucleotides comprising carbocyclic nucleotide |
| CN119818663A (zh) | 2018-05-15 | 2025-04-15 | 全球免疫公司 | 用于诱导细胞免疫应答的重组酵母裂解物 |
| US11186579B2 (en) | 2018-07-06 | 2021-11-30 | Gilead Sciences, Inc. | Therapeutic heterocyclic compounds |
| AU2019297362B2 (en) | 2018-07-06 | 2022-05-26 | Gilead Sciences, Inc. | Therapeutic heterocyclic compounds |
| SG11202012425QA (en) | 2018-07-13 | 2021-01-28 | Gilead Sciences Inc | Pd-1/pd-l1 inhibitors |
| WO2020028097A1 (en) | 2018-08-01 | 2020-02-06 | Gilead Sciences, Inc. | Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid |
| WO2020086556A1 (en) | 2018-10-24 | 2020-04-30 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| WO2020092528A1 (en) | 2018-10-31 | 2020-05-07 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity |
| US11203591B2 (en) | 2018-10-31 | 2021-12-21 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds |
| WO2020178768A1 (en) | 2019-03-07 | 2020-09-10 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 3'3'-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator |
| EP3934757B1 (en) | 2019-03-07 | 2023-02-22 | Institute of Organic Chemistry and Biochemistry ASCR, V.V.I. | 2'3'-cyclic dinucleotides and prodrugs thereof |
| WO2020178770A1 (en) | 2019-03-07 | 2020-09-10 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 3'3'-cyclic dinucleotides and prodrugs thereof |
| TWI751516B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| TW202212339A (zh) | 2019-04-17 | 2022-04-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
| EP3972695A1 (en) | 2019-05-23 | 2022-03-30 | Gilead Sciences, Inc. | Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors |
| CA3140708A1 (en) | 2019-06-18 | 2020-12-24 | Helen Horton | Combination of hepatitis b virus (hbv) vaccines and pyridopyrimidine derivatives |
| WO2020254876A1 (en) * | 2019-06-18 | 2020-12-24 | Janssen Sciences Ireland Unlimited Company | Virus-like particle delivery of hepatitis b virus (hbv) vaccines |
| WO2020263830A1 (en) | 2019-06-25 | 2020-12-30 | Gilead Sciences, Inc. | Flt3l-fc fusion proteins and methods of use |
| US20220257619A1 (en) | 2019-07-18 | 2022-08-18 | Gilead Sciences, Inc. | Long-acting formulations of tenofovir alafenamide |
| WO2021034804A1 (en) | 2019-08-19 | 2021-02-25 | Gilead Sciences, Inc. | Pharmaceutical formulations of tenofovir alafenamide |
| MX2022002270A (es) | 2019-08-29 | 2022-03-22 | Vir Biotechnology Inc | Vacunas contra el virus de la hepatitis b. |
| EP4036111A4 (en) * | 2019-09-27 | 2023-10-25 | Fujirebio Inc. | HEPATITIS B VIRUS CORE ANTIGEN IMMUNOASSAY AND KIT THEREOF |
| DK4037708T3 (da) | 2019-09-30 | 2024-09-30 | Gilead Sciences Inc | HBV-vacciner og fremgangsmåder til at behandle HBV |
| DK4069729T3 (da) | 2019-12-06 | 2025-04-07 | Prec Biosciences Inc | Optimerede, modificerede meganukleaser med specificitet for en genkendelsessekvens i hepatitis b-virusgenomet |
| JP7696909B2 (ja) | 2020-01-09 | 2025-06-23 | ビリオン セラピューティクス,リミティド ライアビリティ カンパニー | ヘルペスウイルス糖タンパク質dと融合したb型肝炎ウイルス抗原をコードするアデノウイルスベクター及びその使用方法 |
| US12285480B2 (en) | 2020-03-11 | 2025-04-29 | Nantcell, Inc. | Method of inducing immunity against SARS-CoV-2 using spike and nucleocapsid-ETSD immunogens delivered by RNA and replication-defective adenoviruses |
| US20210284716A1 (en) | 2020-03-11 | 2021-09-16 | Immunitybio, Inc. | ACE2-Fc Trap |
| US11857620B2 (en) | 2020-03-11 | 2024-01-02 | Immunitybio, Inc. | Method of inducing immunity against SARS-CoV-2 using spike (s) and nucleocapsid (N)-ETSD immunogens delivered by a replication-defective adenovirus |
| WO2021188959A1 (en) | 2020-03-20 | 2021-09-23 | Gilead Sciences, Inc. | Prodrugs of 4'-c-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same |
| WO2022006146A1 (en) * | 2020-06-29 | 2022-01-06 | The Trustees Of Columbia University In The City Of New York | Yeast-based vaccines |
| EP4192474B1 (en) | 2020-08-07 | 2025-09-10 | Gilead Sciences, Inc. | Prodrugs of phosphonamide nucleotide analogues and their pharmaceutical use |
| TW202406932A (zh) | 2020-10-22 | 2024-02-16 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
| WO2022241134A1 (en) | 2021-05-13 | 2022-11-17 | Gilead Sciences, Inc. | COMBINATION OF A TLR8 MODULATING COMPOUND AND ANTI-HBV siRNA THERAPEUTICS |
| AU2022299051B2 (en) | 2021-06-23 | 2025-03-13 | Gilead Sciences, Inc. | Diacylglyercol kinase modulating compounds |
| MX2023014762A (es) | 2021-06-23 | 2024-01-15 | Gilead Sciences Inc | Compuestos moduladores de diacilglicerol quinasa. |
| JP7651018B2 (ja) | 2021-06-23 | 2025-03-25 | ギリアード サイエンシーズ, インコーポレイテッド | ジアシルグリセロールキナーゼ調節化合物 |
| JP7686091B2 (ja) | 2021-06-23 | 2025-05-30 | ギリアード サイエンシーズ, インコーポレイテッド | ジアシルグリセロールキナーゼ調節化合物 |
| WO2023085956A1 (en) * | 2021-11-09 | 2023-05-19 | Avalia Immunotherapies Limited | Novel therapeutic vaccines |
| WO2024220982A1 (en) * | 2023-04-21 | 2024-10-24 | The Wistar Institute Of Anatomy And Biology | Compositions comprising aptamers and methods of modulating the immune response using the same |
| WO2025240246A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies with ribavirin |
| WO2025240244A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies comprising bulevirtide and lonafarnib for use in the treatment of hepatitis d virus infection |
| WO2025240243A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies with bulevirtide and an inhibitory nucleic acid targeting hepatitis b virus |
| WO2025240242A1 (en) | 2024-05-13 | 2025-11-20 | Gilead Sciences, Inc. | Combination therapies with ribavirin |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2486400B1 (fr) | 1980-07-09 | 1986-05-30 | Univablot | Medicaments a base de levures ou de leurs extraits insolubles |
| NZ199722A (en) | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| US4775622A (en) | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| US5310654A (en) | 1985-07-31 | 1994-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining virulence of Yersinia |
| US5164485A (en) | 1985-08-20 | 1992-11-17 | Takeda Chemical Industries, Ltd. | Modified hepatitis B virus surface antigen P31 and production thereof |
| US5234830A (en) | 1988-02-03 | 1993-08-10 | Suntory Limited | DNA encoding a KEX2 endoprotease without a C-terminal hydrophobic region |
| US6306625B1 (en) * | 1988-12-30 | 2001-10-23 | Smithkline Beecham Biologicals, Sa | Method for obtaining expression of mixed polypeptide particles in yeast |
| IL95019A0 (en) | 1989-08-09 | 1991-06-10 | Mycogen Corp | Process for encapsulation of biologicals |
| US6607727B1 (en) * | 1991-08-26 | 2003-08-19 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus |
| WO1994012617A1 (en) * | 1992-11-25 | 1994-06-09 | International Biotechnology Laboratories, Inc. | Hepatitis b virus vaccines |
| US5413914A (en) | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5830463A (en) | 1993-07-07 | 1998-11-03 | University Technology Corporation | Yeast-based delivery vehicles |
| US5858378A (en) | 1996-05-02 | 1999-01-12 | Galagen, Inc. | Pharmaceutical composition comprising cryptosporidium parvum oocysts antigen and whole cell candida species antigen |
| JP3713900B2 (ja) | 1996-07-19 | 2005-11-09 | ソニー株式会社 | 負極材料及びこれを用いた非水電解液二次電池 |
| CZ302092B6 (cs) * | 1998-02-12 | 2010-10-06 | Immune Complex, Corporation | Konjugát upraveného jaderného proteinu hepatitidy B, jeho cástice, inokulum a zpusob indukce protilátek |
| AU2358201A (en) * | 1999-12-03 | 2001-06-12 | Innogenetics N.V. | New hbv sequences |
| GB0216074D0 (en) * | 2002-07-11 | 2002-08-21 | Weatherford Lamb | Improving collapse resistance of tubing |
| US20020044948A1 (en) | 2000-03-15 | 2002-04-18 | Samir Khleif | Methods and compositions for co-stimulation of immunological responses to peptide antigens |
| AU1951001A (en) | 2000-04-06 | 2001-09-17 | Panacea Pharm Llc | Microbial delivery system |
| AU2002225681A1 (en) | 2000-11-15 | 2002-05-27 | Globe Immune, Inc. | Yeast-dentritic cell vaccines and uses thereof |
| CN1171636C (zh) * | 2001-06-06 | 2004-10-20 | 中国人民解放军第二军医大学 | 一种乙型肝炎dna疫苗 |
| US8029803B2 (en) * | 2002-06-20 | 2011-10-04 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| US8343502B2 (en) | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
| KR101455222B1 (ko) | 2002-12-16 | 2014-10-31 | 글로브이뮨 | 면역 요법으로서의 효모계 백신 |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| US20070054262A1 (en) * | 2003-03-28 | 2007-03-08 | Baker Denise M | Methods of identifying optimal variants of peptide epitopes |
| DE10339927A1 (de) * | 2003-08-29 | 2005-03-24 | Rhein Biotech Gesellschaft für neue Biotechnologische Prozesse und Produkte mbH | Zusammensetzung zur Prophylaxe/Therapie von HBV-Infektionen und HBV-vermittelten Erkrankungen |
| EP2460533A3 (en) | 2004-10-18 | 2014-01-08 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| SG163572A1 (en) | 2005-07-11 | 2010-08-30 | Globeimmune Inc | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
| US20070172503A1 (en) | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
| US7736642B2 (en) | 2006-02-02 | 2010-06-15 | Globeimmune, Inc. | Yeast-based vaccine for inducing an immune response |
| BRPI0709340A2 (pt) | 2006-03-27 | 2013-04-16 | Globeimmune, Inc. | mutaÇço ras e composiÇÕes e mÉtodos de uso da mesma |
| KR100836745B1 (ko) * | 2007-01-31 | 2008-06-10 | (주)두비엘 | Hbv 백신 및 그의 제조 방법 |
| WO2008097863A2 (en) | 2007-02-02 | 2008-08-14 | Globeimmune, Inc. | Methods for producing yeast-based vaccines |
| CN101036784B (zh) * | 2007-03-09 | 2010-11-10 | 中国人民解放军第二军医大学 | 一种乙型肝炎治疗性细胞毒性t细胞表位疫苗及其制备方法 |
| US8501167B2 (en) | 2007-03-19 | 2013-08-06 | Globeimmune, Inc. | Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer |
| WO2010033841A1 (en) | 2008-09-19 | 2010-03-25 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis c virus infection |
| WO2010065626A1 (en) | 2008-12-02 | 2010-06-10 | Globeimmune, Inc. | Genotyping tools, methods and kits |
| MX2011010977A (es) | 2009-04-17 | 2012-02-29 | Us Health | Composiciones inmunoterapeuticas combinadas contra cancer y metodos. |
| CA2774326C (en) | 2009-09-14 | 2023-11-07 | Donald Bellgrau | Modulation of yeast-based immunotherapy products and responses |
| EP2547792A4 (en) * | 2010-03-14 | 2013-11-27 | Globeimmune Inc | PHARMACOGENOMIC TREATMENT AND ADAPTATION TO THE RESPONSE OF AN INFECTIOUS DISEASE USING YEAST IMMUNOTHERAPY |
| WO2012019127A2 (en) | 2010-08-05 | 2012-02-09 | The Regents Of The University Of Colorado | Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases |
| US9254320B2 (en) | 2010-12-17 | 2016-02-09 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| JP5745102B2 (ja) | 2011-02-12 | 2015-07-08 | グローブイミューン,インコーポレイテッド | 慢性b型肝炎感染症のための酵母系免疫療法組成物 |
| MX350661B (es) | 2011-03-17 | 2017-09-13 | Us Health | Composiciones inmunoterapeuticas de levadura-brachyuri. |
| CN103732250A (zh) | 2011-06-14 | 2014-04-16 | 全球免疫股份有限公司 | 基于酵母的治疗或预防丁型肝炎病毒感染的组合物和方法 |
| SG10201607663YA (en) | 2011-08-17 | 2016-11-29 | Globeimmune Inc | Yeast-muc1 immunotherapeutic compositions and uses thereof |
-
2012
- 2012-02-09 JP JP2013553534A patent/JP5745102B2/ja active Active
- 2012-02-09 PE PE2013001865A patent/PE20140844A1/es not_active Application Discontinuation
- 2012-02-09 ES ES12744328.1T patent/ES2643389T3/es active Active
- 2012-02-09 AU AU2012214394A patent/AU2012214394B2/en active Active
- 2012-02-09 US US13/984,888 patent/US8877205B2/en active Active
- 2012-02-09 CA CA2827150A patent/CA2827150C/en active Active
- 2012-02-09 MA MA36222A patent/MA34956B1/fr unknown
- 2012-02-09 AP AP2013007110A patent/AP2013007110A0/xx unknown
- 2012-02-09 EP EP12744328.1A patent/EP2672991B1/en active Active
- 2012-02-09 EP EP17175311.4A patent/EP3266464A3/en not_active Withdrawn
- 2012-02-09 SG SG2013060777A patent/SG192285A1/en unknown
- 2012-02-09 WO PCT/US2012/024409 patent/WO2012109404A1/en not_active Ceased
- 2012-02-09 PH PH1/2013/501683A patent/PH12013501683A1/en unknown
- 2012-02-09 CN CN201280018222.5A patent/CN103476426B/zh active Active
- 2012-02-09 KR KR1020137024018A patent/KR102026840B1/ko active Active
- 2012-02-09 BR BR112013020425A patent/BR112013020425A2/pt not_active IP Right Cessation
- 2012-02-09 EA EA201391170A patent/EA028659B1/ru not_active IP Right Cessation
- 2012-02-10 TW TW101104436A patent/TWI504608B/zh active
- 2012-09-02 UA UAA201310911A patent/UA112859C2/uk unknown
-
2013
- 2013-03-13 US US13/798,837 patent/US8722054B2/en active Active
- 2013-08-12 CL CL2013002334A patent/CL2013002334A1/es unknown
- 2013-08-28 ZA ZA2013/06481A patent/ZA201306481B/en unknown
- 2013-08-30 EC ECSP13012862 patent/ECSP13012862A/es unknown
- 2013-08-31 CR CR20130424A patent/CR20130424A/es unknown
- 2013-09-12 CO CO13216900A patent/CO6791572A2/es unknown
- 2013-09-29 IL IL227900A patent/IL227900B/en active IP Right Grant
-
2014
- 2014-02-19 US US14/184,481 patent/US8961988B2/en active Active
- 2014-09-23 US US14/494,235 patent/US9290547B2/en active Active
-
2015
- 2015-01-07 US US14/591,592 patent/US9428556B2/en active Active
- 2015-02-12 JP JP2015025534A patent/JP5911983B2/ja active Active
-
2016
- 2016-03-30 JP JP2016068623A patent/JP6109989B2/ja active Active
- 2016-07-18 US US15/212,930 patent/US9943591B2/en active Active
- 2016-11-10 AU AU2016256751A patent/AU2016256751B2/en active Active
-
2017
- 2017-03-08 JP JP2017043689A patent/JP2017105834A/ja active Pending
-
2018
- 2018-03-01 US US15/909,112 patent/US10441650B2/en active Active
- 2018-06-13 HK HK18107680.0A patent/HK1248120A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016128513A5 (enExample) | ||
| JP2015096557A5 (enExample) | ||
| Spyrou et al. | Hepatitis B: current status of therapy and future therapies | |
| Kim et al. | Toward a complete cure for chronic hepatitis B: Novel therapeutic targets for hepatitis B virus | |
| Liang et al. | Present and future therapies of hepatitis B: from discovery to cure | |
| Paladini et al. | The worldwide impact of vaccination on the control and protection of viral hepatitis B | |
| CN110612118B (zh) | 用于引起针对hbv的免疫应答的病毒样粒子 | |
| RU2749730C1 (ru) | Бисдиазабицикло-соединение для лечения и/или профилактики заболеваний или расстройств, связанных с вирусом гепатита | |
| Li et al. | Research progress of therapeutic vaccines for treating chronic hepatitis B | |
| JP2014507144A5 (ja) | 慢性b型肝炎感染症のための酵母系免疫療法組成物 | |
| JP2014527404A5 (enExample) | ||
| JP2014523878A5 (enExample) | ||
| WO2008103380A3 (en) | Hepatitis b virus compositions and methods of use | |
| JP2017515508A5 (enExample) | ||
| Yoshida et al. | Intranasal therapeutic vaccine containing HBsAg and HBcAg for patients with chronic hepatitis B; 18 months follow‐up results of phase IIa clinical study | |
| Karimkhanilouyi et al. | Nucleic acid vaccines for hepatitis B and C virus | |
| Jilg | Novel hepatitis B vaccines | |
| Tang et al. | Advances in new antivirals for chronic hepatitis B | |
| AU2017243136B2 (en) | Pharmaceutical composition that includes the surface and nucleocapsid antigens of the hepatitis B virus | |
| Pentón-Arias et al. | Cuban prophylactic and therapeutic vaccines for controlling hepatitis B | |
| CN106421774A (zh) | PreS1用于制备乙肝疫苗以及治疗慢性乙型肝炎的用途 | |
| CN101717433A (zh) | 一种多肽免疫原及其制备方法和应用 | |
| JP2014534262A5 (enExample) | ||
| Wen et al. | Vaccine therapies for chronic hepatitis B: can we go further? | |
| JP2022513438A5 (enExample) |